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Volumn 13, Issue 3, 2017, Pages 174-186

The endocrine manifestations of anorexia nervosa: Mechanisms and management

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; BISPHOSPHONIC ACID DERIVATIVE; ESTROGEN; GESTAGEN; NEUROHYPOPHYSIS HORMONE; ORAL CONTRACEPTIVE AGENT; PARATHYROID HORMONE[1-34]; PRASTERONE; RECOMBINANT SOMATOMEDIN C; SOMATOMEDIN C; TESTOSTERONE; GROWTH HORMONE; LEPTIN;

EID: 84994081864     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2016.175     Document Type: Review
Times cited : (194)

References (183)
  • 1
  • 2
    • 4544357731 scopus 로고    scopus 로고
    • Preservation of neuroendocrine control of reproductive function despite severe undernutrition
    • Miller, K. K. et al. Preservation of neuroendocrine control of reproductive function despite severe undernutrition. J. Clin. Endocrinol. Metab. 89, 4434-4438 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4434-4438
    • Miller, K.K.1
  • 4
    • 84959568925 scopus 로고    scopus 로고
    • Three decades of eating disorders in Dutch primary care: Decreasing incidence of bulimia nervosa but not of anorexia nervosa
    • Smink, F. R. E. et al. Three decades of eating disorders in Dutch primary care: decreasing incidence of bulimia nervosa but not of anorexia nervosa. Psychol. Med. 46, 1189-1196 (2016).
    • (2016) Psychol. Med. , vol.46 , pp. 1189-1196
    • Smink, F.R.E.1
  • 6
    • 84904458909 scopus 로고    scopus 로고
    • Prevalence and severity of DSM-5 eating disorders in a community cohort of adolescents
    • Smink, F. R. E., van Hoeken, D., Oldehinkel, A. J. & Hoek, H. W. Prevalence and severity of DSM-5 eating disorders in a community cohort of adolescents. Int. J. Eat. Disord. 47, 610-619 (2014).
    • (2014) Int. J. Eat. Disord. , vol.47 , pp. 610-619
    • Smink, F.R.E.1    Van Hoeken, D.2    Oldehinkel, A.J.3    Hoek, H.W.4
  • 7
    • 84932137417 scopus 로고    scopus 로고
    • Classification of eating disorders: Comparison of relative prevalence rates using DSM-IV and DSM-5 criteria
    • Mancuso, S. G. et al. Classification of eating disorders: comparison of relative prevalence rates using DSM-IV and DSM-5 criteria. Br. J. Psychiatry 206, 519-520 (2015).
    • (2015) Br. J. Psychiatry , vol.206 , pp. 519-520
    • Mancuso, S.G.1
  • 8
    • 84866734407 scopus 로고    scopus 로고
    • High prevalence of eating disorders not otherwise specified in northwestern Spain: Population-based study
    • Larrañaga, A., Docet, M. F. & García-Mayor, R. V. High prevalence of eating disorders not otherwise specified in northwestern Spain: population-based study. Soc. Psychiatry Psychiatr. Epidemiol. 47, 1669-1673 (2012).
    • (2012) Soc. Psychiatry Psychiatr. Epidemiol. , vol.47 , pp. 1669-1673
    • Larrañaga, A.1    Docet, M.F.2    García-Mayor, R.V.3
  • 9
    • 0025909961 scopus 로고
    • 50-year trends in the incidence of anorexia nervosa in Rochester, Minn.: A population-based study
    • Lucas, A. R., Beard, C. M., O'Fallon, W. M. & Kurland, L. T. 50-year trends in the incidence of anorexia nervosa in Rochester, Minn.: a population-based study. Am. J. Psychiatry 148, 917-922 (1991).
    • (1991) Am. J. Psychiatry , vol.148 , pp. 917-922
    • Lucas, A.R.1    Beard, C.M.2    O'Fallon, W.M.3    Kurland, L.T.4
  • 10
    • 80053537863 scopus 로고    scopus 로고
    • Endocrine dysregulation in anorexia nervosa update
    • Miller, K. K. Endocrine dysregulation in anorexia nervosa update. J. Clin. Endocrinol. Metab. 96, 2939-2949 (2011).
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 2939-2949
    • Miller, K.K.1
  • 11
    • 0034941149 scopus 로고    scopus 로고
    • Long-term outcome of anorexia nervosa in a prospective 21-year follow-up study
    • Löwe, B. et al. Long-term outcome of anorexia nervosa in a prospective 21-year follow-up study. Psychol. Med. 31, 881-890 (2001).
    • (2001) Psychol. Med. , vol.31 , pp. 881-890
    • Löwe, B.1
  • 12
    • 32044441452 scopus 로고    scopus 로고
    • Twelve-year course and outcome predictors of anorexia nervosa
    • Fichter, M. M., Quadflieg, N. & Hedlund, S. Twelve-year course and outcome predictors of anorexia nervosa. Int. J. Eat. Disord. 39, 87-100 (2006).
    • (2006) Int. J. Eat. Disord. , vol.39 , pp. 87-100
    • Fichter, M.M.1    Quadflieg, N.2    Hedlund, S.3
  • 13
    • 0036334936 scopus 로고    scopus 로고
    • The outcome of anorexia nervosa in the 20th century
    • Steinhausen, H.-C. The outcome of anorexia nervosa in the 20th century. Am. J. Psychiatry 159, 1284-1293 (2002).
    • (2002) Am. J. Psychiatry , vol.159 , pp. 1284-1293
    • Steinhausen, H.-C.1
  • 14
    • 14844337547 scopus 로고    scopus 로고
    • Medical findings in outpatients with anorexia nerovsa
    • Miller, K. et al. Medical findings in outpatients with anorexia nerovsa. Arch. Intern. Med. 165, 561-566 (2005).
    • (2005) Arch. Intern. Med. , vol.165 , pp. 561-566
    • Miller, K.1
  • 16
    • 0016269191 scopus 로고
    • Anorexia nervosa - Immaturity of the 24-hour luteinizing hormone secretory pattern
    • Boyar, R. M. et al. Anorexia nervosa - immaturity of the 24-hour luteinizing hormone secretory pattern. N. Engl. J. Med. 291, 861-865 (1974).
    • (1974) N. Engl. J. Med. , vol.291 , pp. 861-865
    • Boyar, R.M.1
  • 17
    • 0018220003 scopus 로고
    • Weight and circadian luteinizing hormone secretory pattern in anorexia nervosa
    • Katz, J. L., Boyar, R., Roffwarg, H., Hellman, L. & Weiner, H. Weight and circadian luteinizing hormone secretory pattern in anorexia nervosa. Psychosom. Med. 40, 549-567 (1978).
    • (1978) Psychosom. Med. , vol.40 , pp. 549-567
    • Katz, J.L.1    Boyar, R.2    Roffwarg, H.3    Hellman, L.4    Weiner, H.5
  • 18
    • 0029896530 scopus 로고    scopus 로고
    • Role of leptin in the neuroendocrine response to fasting
    • Ahima, R. S. et al. Role of leptin in the neuroendocrine response to fasting. Nature 382, 250-252 (1996).
    • (1996) Nature , vol.382 , pp. 250-252
    • Ahima, R.S.1
  • 19
    • 10344238541 scopus 로고    scopus 로고
    • Serum leptin levels in women with anorexia nervosa
    • Grinspoon, S. et al. Serum leptin levels in women with anorexia nervosa. J. Clin. Endocrinol. Metab. 81, 3861-3863 (1996).
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3861-3863
    • Grinspoon, S.1
  • 20
    • 4344690525 scopus 로고    scopus 로고
    • Recombinant human leptin in women with hypothalamic amenorrhea
    • Welt, C. K. et al. Recombinant human leptin in women with hypothalamic amenorrhea. N. Engl. J. Med. 351, 987-997 (2004).
    • (2004) N. Engl. J. Med. , vol.351 , pp. 987-997
    • Welt, C.K.1
  • 21
    • 4344561363 scopus 로고    scopus 로고
    • A role for kisspeptins in the regulation of gonadotropin secretion in the mouse
    • Gottsch, M. L. et al. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Endocrinology 145, 4073-4077 (2004).
    • (2004) Endocrinology , vol.145 , pp. 4073-4077
    • Gottsch, M.L.1
  • 22
    • 0141814637 scopus 로고    scopus 로고
    • Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54
    • De Roux, N. et al. Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54. Proc. Natl Acad. Sci. USA 100, 10972-10976 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 10972-10976
    • De Roux, N.1
  • 23
    • 70449111663 scopus 로고    scopus 로고
    • Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis
    • Jayasena, C. N. et al. Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis. J. Clin. Endocrinol. Metab. 94, 4315-4323 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 4315-4323
    • Jayasena, C.N.1
  • 24
    • 78751621790 scopus 로고    scopus 로고
    • A genetic basis for functional hypothalamic amenorrhea
    • Caronia, L. M. et al. A genetic basis for functional hypothalamic amenorrhea. N. Engl. J. Med. 364, 215-225 (2011).
    • (2011) N. Engl. J. Med. , vol.364 , pp. 215-225
    • Caronia, L.M.1
  • 25
    • 34147150332 scopus 로고    scopus 로고
    • Androgens in women with anorexia nervosa and normal-weight women with hypothalamic amenorrhea
    • Miller, K. K. et al. Androgens in women with anorexia nervosa and normal-weight women with hypothalamic amenorrhea. J. Clin. Endocrinol. Metab. 92, 1334-1339 (2007).
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 1334-1339
    • Miller, K.K.1
  • 26
    • 0031014122 scopus 로고    scopus 로고
    • Resumption of menses in anorexia nervosa
    • Golden, N. H. et al. Resumption of menses in anorexia nervosa. Arch. Pediatr. Adolesc. Med. 151, 16-21 (1997).
    • (1997) Arch. Pediatr. Adolesc. Med. , vol.151 , pp. 16-21
    • Golden, N.H.1
  • 27
    • 33745803261 scopus 로고    scopus 로고
    • Amenorrhea after weight recover in anorexia nervosa: Role of body composition and endocrine abnormalities
    • Jacoangeli, F. et al. Amenorrhea after weight recover in anorexia nervosa: role of body composition and endocrine abnormalities. Eat. Weight Disord. 11, e20-e26 (2006).
    • (2006) Eat. Weight Disord. , vol.11 , pp. e20-e26
    • Jacoangeli, F.1
  • 28
    • 9144224949 scopus 로고    scopus 로고
    • Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism
    • Misra, M. et al. Alterations in growth hormone secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J. Clin. Endocrinol. Metab. 88, 5615-5623 (2003).
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 5615-5623
    • Misra, M.1
  • 29
    • 0033304527 scopus 로고    scopus 로고
    • Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: Indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis
    • Støving, R. K. et al. Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis. J. Clin. Endocrinol. Metab. 84, 2056-2063 (1999).
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 2056-2063
    • Støving, R.K.1
  • 30
    • 0000129710 scopus 로고
    • Hypoglycemia: A potent stimulus to secretion of growth hormone
    • Roth, J., Glick, S. M., Yalow, R. S. & Berson, S. A. Hypoglycemia: a potent stimulus to secretion of growth hormone. Science 140, 987-988 (1963).
    • (1963) Science , vol.140 , pp. 987-988
    • Roth, J.1    Glick, S.M.2    Yalow, R.S.3    Berson, S.A.4
  • 31
    • 0026775341 scopus 로고
    • The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins
    • Counts, D. R., Gwirtsman, H., Carlsson, L. M., Lesem, M. & Cutler, G. B. The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins. J. Clin. Endocrinol. Metab. 75, 762-767 (1992).
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 762-767
    • Counts, D.R.1    Gwirtsman, H.2    Carlsson, L.M.3    Lesem, M.4    Cutler, G.B.5
  • 32
    • 34347219031 scopus 로고    scopus 로고
    • Bioactive insulin-like growth factor (IGF) I and IGF-binding protein-1 in anorexia nervosa
    • Støving, R. K. et al. Bioactive insulin-like growth factor (IGF) I and IGF-binding protein-1 in anorexia nervosa. J. Clin. Endocrinol. Metab. 92, 2323-2329 (2007).
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 2323-2329
    • Støving, R.K.1
  • 33
    • 0028152830 scopus 로고
    • Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa
    • Golden, N. H. et al. Disturbances in growth hormone secretion and action in adolescents with anorexia nervosa. J. Pediatr. 125, 655-660 (1994).
    • (1994) J. Pediatr. , vol.125 , pp. 655-660
    • Golden, N.H.1
  • 34
    • 0037316167 scopus 로고    scopus 로고
    • Stunting of growth as a major feature of anorexia nervosa in male adolescents
    • Modan-Moses, D. et al. Stunting of growth as a major feature of anorexia nervosa in male adolescents. Pediatrics 111, 270-276 (2003).
    • (2003) Pediatrics , vol.111 , pp. 270-276
    • Modan-Moses, D.1
  • 35
    • 84866509453 scopus 로고    scopus 로고
    • Linear growth and final height characteristics in adolescent females with anorexia nervosa
    • Modan-Moses, D. et al. Linear growth and final height characteristics in adolescent females with anorexia nervosa. PLoS ONE 7, e45504 (2012).
    • (2012) PLoS ONE , vol.7
    • Modan-Moses, D.1
  • 36
    • 45549095622 scopus 로고    scopus 로고
    • Determinants of height in adolescent girls with anorexia nervosa
    • Prabhakaran, R. et al. Determinants of height in adolescent girls with anorexia nervosa. Pediatrics 121, e1517-e1523 (2008).
    • (2008) Pediatrics , vol.121 , pp. e1517-e1523
    • Prabhakaran, R.1
  • 37
    • 77952165770 scopus 로고    scopus 로고
    • Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice
    • Zhao, T.-J. et al. Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice. Proc. Natl Acad. Sci. USA 107, 7467-7472 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 7467-7472
    • Zhao, T.-J.1
  • 38
    • 84871698475 scopus 로고    scopus 로고
    • The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice
    • Gahete, M. D., Córdoba-Chacón, J., Luque, R. M. & Kineman, R. D. The rise in growth hormone during starvation does not serve to maintain glucose levels or lean mass but is required for appropriate adipose tissue response in female mice. Endocrinology 154, 263-269 (2013).
    • (2013) Endocrinology , vol.154 , pp. 263-269
    • Gahete, M.D.1    Córdoba-Chacón, J.2    Luque, R.M.3    Kineman, R.D.4
  • 39
    • 0034697846 scopus 로고    scopus 로고
    • Identification of a novel FGF, FGF-21, preferentially expressed in the liver
    • Nishimura, T., Nakatake, Y., Konishi, M. & Itoh, N. Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Biochim. Biophys. Acta 1492, 203-206 (2000).
    • (2000) Biochim. Biophys. Acta , vol.1492 , pp. 203-206
    • Nishimura, T.1    Nakatake, Y.2    Konishi, M.3    Itoh, N.4
  • 40
    • 48349146527 scopus 로고    scopus 로고
    • Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    • Zhang, X. et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes 57, 1246-1253 (2008).
    • (2008) Diabetes , vol.57 , pp. 1246-1253
    • Zhang, X.1
  • 41
    • 34249686631 scopus 로고    scopus 로고
    • Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21
    • Inagaki, T. et al. Endocrine regulation of the fasting response by PPARα-mediated induction of fibroblast growth factor 21. Cell Metab. 5, 415-425 (2007).
    • (2007) Cell Metab. , vol.5 , pp. 415-425
    • Inagaki, T.1
  • 42
    • 45649085226 scopus 로고    scopus 로고
    • Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
    • Inagaki, T. et al. Inhibition of growth hormone signaling by the fasting-induced hormone FGF21. Cell Metab. 8, 77-83 (2008).
    • (2008) Cell Metab. , vol.8 , pp. 77-83
    • Inagaki, T.1
  • 44
    • 0034489210 scopus 로고    scopus 로고
    • Insulin regulation of human hepatic growth hormone receptors: Divergent effects on biosynthesis and surface translocation
    • Leung, K.-C. Insulin regulation of human hepatic growth hormone receptors: divergent effects on biosynthesis and surface translocation. J. Clin. Endocrinol. Metab. 85, 4712-4720 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 4712-4720
    • Leung, K.-C.1
  • 45
    • 17744384713 scopus 로고    scopus 로고
    • Effects of recombinant human insulin-like growth factor I administration on spontaneous and growth hormone (GH)-releasing hormone-stimulated GH secretion in anorexia nervosa
    • Gianotti, L. et al. Effects of recombinant human insulin-like growth factor I administration on spontaneous and growth hormone (GH)-releasing hormone-stimulated GH secretion in anorexia nervosa. J. Clin. Endocrinol. Metab. 85, 2805-2809 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 2805-2809
    • Gianotti, L.1
  • 46
    • 0033540056 scopus 로고    scopus 로고
    • Ghrelin is a growth-hormone-releasing acylated peptide from stomach
    • Kojima, M. et al. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 402, 656-660 (1999).
    • (1999) Nature , vol.402 , pp. 656-660
    • Kojima, M.1
  • 47
    • 23044437723 scopus 로고    scopus 로고
    • Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents
    • Misra, M. et al. Secretory dynamics of ghrelin in adolescent girls with anorexia nervosa and healthy adolescents. Am. J. Physiol. Endocrinol. Metab. 289, E347-E356 (2005).
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289 , pp. E347-E356
    • Misra, M.1
  • 48
    • 0034455422 scopus 로고    scopus 로고
    • The relationship between bone turnover and body weight, serum insulin-like growth factor (IGF) I, and serum IGF-binding protein levels in patients with anorexia nervosa
    • Hotta, M. et al. The relationship between bone turnover and body weight, serum insulin-like growth factor (IGF) I, and serum IGF-binding protein levels in patients with anorexia nervosa. J. Clin. Endocrinol. Metab. 85, 200-206 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 200-206
    • Hotta, M.1
  • 49
    • 0030854808 scopus 로고    scopus 로고
    • Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: Effect of short-and long-term weight recuperation
    • Argente, J. et al. Multiple endocrine abnormalities of the growth hormone and insulin-like growth factor axis in patients with anorexia nervosa: effect of short-and long-term weight recuperation. J. Clin. Endocrinol. Metab. 82, 2084-2092 (1997).
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2084-2092
    • Argente, J.1
  • 50
    • 78049521759 scopus 로고    scopus 로고
    • Effects of recombinant human growth hormone in anorexia nervosa: A randomized, placebo-controlled study
    • Fazeli, P. K. et al. Effects of recombinant human growth hormone in anorexia nervosa: a randomized, placebo-controlled study. J. Clin. Endocrinol. Metab. 95, 4889-4897 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 4889-4897
    • Fazeli, P.K.1
  • 51
    • 0017331377 scopus 로고
    • Cortisol secretion and metabolism in anorexia nervosa
    • Boyar, R. et al. Cortisol secretion and metabolism in anorexia nervosa. N. Engl. J. Med. 296, 190-193 (1977).
    • (1977) N. Engl. J. Med. , vol.296 , pp. 190-193
    • Boyar, R.1
  • 52
    • 0019305409 scopus 로고
    • Relationship between weight gain and hypothalamic pituitary adrenal function in patients with anorexia nervosa
    • Doerr, P., Fichter, M., Pirke, K. & Lund, R. Relationship between weight gain and hypothalamic pituitary adrenal function in patients with anorexia nervosa. J. Steroid Biochem. 13, 529-537 (1980).
    • (1980) J. Steroid Biochem. , vol.13 , pp. 529-537
    • Doerr, P.1    Fichter, M.2    Pirke, K.3    Lund, R.4
  • 53
    • 33646674069 scopus 로고    scopus 로고
    • Role of cortisol in menstrual recovery in adolescent girls with anorexia nervosa
    • Misra, M. et al. Role of cortisol in menstrual recovery in adolescent girls with anorexia nervosa. Pediatr. Res. 59, 598-603 (2006).
    • (2006) Pediatr. Res. , vol.59 , pp. 598-603
    • Misra, M.1
  • 54
    • 0025015203 scopus 로고
    • Abnormal cortisol secretion and responses to corticotropin-releasing hormone in women with hypothalamic amenorrhea
    • Biller, B. M., Federoff, H. J., Koenig, J. I. & Klibanski, A. Abnormal cortisol secretion and responses to corticotropin-releasing hormone in women with hypothalamic amenorrhea. J. Clin. Endocrinol. Metab. 70, 311-317 (1990).
    • (1990) J. Clin. Endocrinol. Metab. , vol.70 , pp. 311-317
    • Biller, B.M.1    Federoff, H.J.2    Koenig, J.I.3    Klibanski, A.4
  • 55
    • 6344238791 scopus 로고    scopus 로고
    • Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism
    • Misra, M. et al. Alterations in cortisol secretory dynamics in adolescent girls with anorexia nervosa and effects on bone metabolism. J. Clin. Endocrinol. Metab. 89, 4972-4980 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 4972-4980
    • Misra, M.1
  • 56
    • 73249122693 scopus 로고    scopus 로고
    • Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosa
    • Lawson, E. et al. Hypercortisolemia is associated with severity of bone loss and depression in hypothalamic amenorrhea and anorexia nervosa. J. Clin. Endocrinol. Metab. 94, 4710-4716 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 4710-4716
    • Lawson, E.1
  • 57
    • 79952572943 scopus 로고    scopus 로고
    • The neuroendocrine basis of anorexia nervosa and its impact on bone metabolism
    • Misra, M. & Klibanski, A. The neuroendocrine basis of anorexia nervosa and its impact on bone metabolism. Neuroendocrinology 93, 65-73 (2011).
    • (2011) Neuroendocrinology , vol.93 , pp. 65-73
    • Misra, M.1    Klibanski, A.2
  • 58
    • 17744374270 scopus 로고    scopus 로고
    • Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: Comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone
    • Arvat, E. et al. Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone. J. Clin. Endocrinol. Metab. 86, 1169-1174 (2001).
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 1169-1174
    • Arvat, E.1
  • 59
    • 0141786987 scopus 로고    scopus 로고
    • Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin
    • Mozid, A. M. et al. Ghrelin is released from rat hypothalamic explants and stimulates corticotrophin-releasing hormone and arginine-vasopressin. Horm. Metab. Res. 35, 455-459 (2003).
    • (2003) Horm. Metab. Res. , vol.35 , pp. 455-459
    • Mozid, A.M.1
  • 60
    • 18844405938 scopus 로고    scopus 로고
    • Hormonal determinants of regional body composition in adolescent girls with anorexia nervosa and controls
    • Misra, M. et al. Hormonal determinants of regional body composition in adolescent girls with anorexia nervosa and controls. J. Clin. Endocrinol. Metab. 90, 2580-2587 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 2580-2587
    • Misra, M.1
  • 61
    • 0035046941 scopus 로고    scopus 로고
    • Changes in regional fat distribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa
    • Grinspoon, S. et al. Changes in regional fat distribution and the effects of estrogen during spontaneous weight gain in women with anorexia nervosa. Am. J. Clin. Nutr. 73, 865-869 (2001).
    • (2001) Am. J. Clin. Nutr. , vol.73 , pp. 865-869
    • Grinspoon, S.1
  • 62
    • 84885165318 scopus 로고    scopus 로고
    • Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food-motivation neurocircuitry in anorexia nervosa
    • Lawson, E. A. et al. Increased hypothalamic-pituitary-adrenal drive is associated with decreased appetite and hypoactivation of food-motivation neurocircuitry in anorexia nervosa. Eur. J. Endocrinol. 169, 639-647 (2013).
    • (2013) Eur. J. Endocrinol. , vol.169 , pp. 639-647
    • Lawson, E.A.1
  • 63
    • 21944438873 scopus 로고    scopus 로고
    • Body fat redistribution after weight gain in women with anorexia nervosa
    • Mayer, L. et al. Body fat redistribution after weight gain in women with anorexia nervosa. Am. J. Clin. Nutr. 81, 1286-1291 (2005).
    • (2005) Am. J. Clin. Nutr. , vol.81 , pp. 1286-1291
    • Mayer, L.1
  • 64
    • 33750704556 scopus 로고    scopus 로고
    • An investigation of hypothalamic-pituitary-adrenal axis hyperactivity in anorexia nervosa: The role of CRH and AVP
    • Connan, F. et al. An investigation of hypothalamic-pituitary-adrenal axis hyperactivity in anorexia nervosa: the role of CRH and AVP. J. Psychiatr. Res. 41, 131-143 (2007).
    • (2007) J. Psychiatr. Res. , vol.41 , pp. 131-143
    • Connan, F.1
  • 65
    • 65249142310 scopus 로고    scopus 로고
    • Adrenal glucocorticoid and androgen precursor dissociation in anorexia nervosa
    • Lawson, E. A. et al. Adrenal glucocorticoid and androgen precursor dissociation in anorexia nervosa. J. Clin. Endocrinol. Metab. 94, 1367-1371 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 1367-1371
    • Lawson, E.A.1
  • 66
    • 0032919545 scopus 로고    scopus 로고
    • Changes in bone turnover markers and menstrual function after short-term oral DHEA in young women with anorexia nervosa
    • Gordon, C. M. et al. Changes in bone turnover markers and menstrual function after short-term oral DHEA in young women with anorexia nervosa. J. Bone Miner. Res. 14, 136-145 (1999).
    • (1999) J. Bone Miner. Res. , vol.14 , pp. 136-145
    • Gordon, C.M.1
  • 67
    • 0020660781 scopus 로고
    • Subnormal plasma dehydroisoandrosterone to cortisol ratio in anorexia nervosa: A second hormonal parameter of ontogenic regression
    • Zumoff, B. et al. Subnormal plasma dehydroisoandrosterone to cortisol ratio in anorexia nervosa: a second hormonal parameter of ontogenic regression. J. Clin. Endocrinol. Metab. 56, 668-672 (1983).
    • (1983) J. Clin. Endocrinol. Metab. , vol.56 , pp. 668-672
    • Zumoff, B.1
  • 68
    • 77952751421 scopus 로고    scopus 로고
    • Hormonal profile heterogeneity and short-term physical risk in restrictive anorexia nervosa
    • Estour, B. et al. Hormonal profile heterogeneity and short-term physical risk in restrictive anorexia nervosa. J. Clin. Endocrinol. Metab. 95, 2203-2210 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 2203-2210
    • Estour, B.1
  • 69
    • 34547927987 scopus 로고    scopus 로고
    • Clinical review 86: Euthyroid sick syndrome: Is it a misnomer?
    • Chopra, I. J. Clinical review 86: euthyroid sick syndrome: is it a misnomer? J. Clin. Endocrinol. Metab. 82, 329-334 (1997).
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 329-334
    • Chopra, I.J.1
  • 71
    • 0018098185 scopus 로고
    • Hypothalamo-pituitary-thyroid function in anorexia nervosa: Influence of weight gain
    • Leslie, R. D., Isaacs, A. J., Gomez, J., Raggatt, P. R. & Bayliss, R. Hypothalamo-pituitary-thyroid function in anorexia nervosa: influence of weight gain. Br. Med. J. 2, 526-528 (1978).
    • (1978) Br. Med. J. , vol.2 , pp. 526-528
    • Leslie, R.D.1    Isaacs, A.J.2    Gomez, J.3    Raggatt, P.R.4    Bayliss, R.5
  • 72
    • 0032528002 scopus 로고    scopus 로고
    • The arginine vasopressin and corticotrophin-releasing hormone gene transcription responses to varied frequencies of repeated stress in rats
    • Ma, X. M. & Lightman, S. L. The arginine vasopressin and corticotrophin-releasing hormone gene transcription responses to varied frequencies of repeated stress in rats. J. Physiol. (Lond.) 510, 605-614 (1998).
    • (1998) J. Physiol. (Lond.) , vol.510 , pp. 605-614
    • Ma, X.M.1    Lightman, S.L.2
  • 73
    • 0032787663 scopus 로고    scopus 로고
    • Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: Sex differences between major depressives and matched control subjects
    • Rubin, R. T., O'Toole, S. M., Rhodes, M. E., Sekula, L. K. & Czambel, R. K. Hypothalamo-pituitary-adrenal cortical responses to low-dose physostigmine and arginine vasopressin administration: sex differences between major depressives and matched control subjects. Psychiatry Res. 89, 1-20 (1999).
    • (1999) Psychiatry Res. , vol.89 , pp. 1-20
    • Rubin, R.T.1    O'Toole, S.M.2    Rhodes, M.E.3    Sekula, L.K.4    Czambel, R.K.5
  • 74
    • 0020630919 scopus 로고
    • Abnormalities in plasma and cerebrospinal-fluid arginine vasopressin in patients with anorexia nervosa
    • Gold, P. W., Kaye, W., Robertson, G. L. & Ebert, M. Abnormalities in plasma and cerebrospinal-fluid arginine vasopressin in patients with anorexia nervosa. N. Engl. J. Med. 308, 1117-1123 (1983).
    • (1983) N. Engl. J. Med. , vol.308 , pp. 1117-1123
    • Gold, P.W.1    Kaye, W.2    Robertson, G.L.3    Ebert, M.4
  • 75
    • 16244392715 scopus 로고    scopus 로고
    • Sodium depletion and hemoconcentration: Overlooked complications in patients with anorexia nervosa?
    • Caregaro, L., Di Pascoli, L., Favaro, A., Nardi, M. & Santonastaso, P. Sodium depletion and hemoconcentration: overlooked complications in patients with anorexia nervosa? Nutrition 21, 438-445 (2005).
    • (2005) Nutrition , vol.21 , pp. 438-445
    • Caregaro, L.1    Di Pascoli, L.2    Favaro, A.3    Nardi, M.4    Santonastaso, P.5
  • 76
    • 79951756168 scopus 로고    scopus 로고
    • Polydipsia and hyponatremia in a woman with anorexia nervosa
    • Bahia, A., Chu, E. S. & Mehler, P. S. Polydipsia and hyponatremia in a woman with anorexia nervosa. Int. J. Eat. Disord. 44, 186-188 (2011).
    • (2011) Int. J. Eat. Disord. , vol.44 , pp. 186-188
    • Bahia, A.1    Chu, E.S.2    Mehler, P.S.3
  • 78
    • 84903532738 scopus 로고    scopus 로고
    • Clinical practice guideline on diagnosis and treatment of hyponatraemia
    • Spasovski, G. et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur. J. Endocrinol. 170, G1-G47 (2014).
    • (2014) Eur. J. Endocrinol. , vol.170 , pp. G1-G47
    • Spasovski, G.1
  • 80
    • 79952565084 scopus 로고    scopus 로고
    • Hypokalemia and sudden cardiac death
    • Kjeldsen, K. Hypokalemia and sudden cardiac death. Exp. Clin. Cardiol. 15, e96-e99 (2010).
    • (2010) Exp. Clin. Cardiol. , vol.15 , pp. e96-e99
    • Kjeldsen, K.1
  • 81
    • 33748064640 scopus 로고    scopus 로고
    • Treatment of patients with eating disorders, third edition. American Psychiatric Association
    • American Psychiatric Association
    • American Psychiatric Association. Treatment of patients with eating disorders, third edition. American Psychiatric Association. Am. J. Psychiatry 163 (Suppl.), 4-54 (2006).
    • (2006) Am. J. Psychiatry , vol.163 , pp. 4-54
  • 83
    • 85012037293 scopus 로고    scopus 로고
    • NHS Foundation Trust. Guideline for the management of refeeding syndrome (adults). NHS
    • NHS Foundation Trust. Guideline for the management of refeeding syndrome (adults). NHS http://www.formulary.cht.nhs.uk/pdf,-doc-files-etc/MMC/089-Refeeding-Syndrome-3rd-Edition.pdf (2011).
    • (2011)
  • 84
    • 81755166010 scopus 로고    scopus 로고
    • Decreased nocturnal oxytocin levels in anorexa nervosa are associated with low bone mineral density and fat mass
    • Lawson, E. et al. Decreased nocturnal oxytocin levels in anorexa nervosa are associated with low bone mineral density and fat mass. J. Clin. Psychiatry 72, 1546-1551 (2011).
    • (2011) J. Clin. Psychiatry , vol.72 , pp. 1546-1551
    • Lawson, E.1
  • 85
    • 84878253083 scopus 로고    scopus 로고
    • Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa
    • Lawson, E. A. et al. Postprandial oxytocin secretion is associated with severity of anxiety and depressive symptoms in anorexia nervosa. J. Clin. Psychiatry 74, e451-e457 (2013).
    • (2013) J. Clin. Psychiatry , vol.74 , pp. e451-e457
    • Lawson, E.A.1
  • 86
    • 0344393018 scopus 로고    scopus 로고
    • α-melanocyte-stimulating hormone stimulates oxytocin release from the dendrites of hypothalamic neurons while inhibiting oxytocin release from their terminals in the neurohypophysis
    • Sabatier, N. et al. α-melanocyte-stimulating hormone stimulates oxytocin release from the dendrites of hypothalamic neurons while inhibiting oxytocin release from their terminals in the neurohypophysis. J. Neurosci. 23, 10351-10358 (2003).
    • (2003) J. Neurosci. , vol.23 , pp. 10351-10358
    • Sabatier, N.1
  • 87
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • Zhang, Y. et al. Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432 (1994).
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1
  • 88
    • 23944434401 scopus 로고    scopus 로고
    • Secretory dynamics of leptin in adolescent girls with anorexia nervosa and healthy adolescents
    • Misra, M. et al. Secretory dynamics of leptin in adolescent girls with anorexia nervosa and healthy adolescents. Am. J. Physiol. Endocrinol. Metab. 289, E373-E381 (2005).
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.289 , pp. E373-E381
    • Misra, M.1
  • 89
    • 0033799526 scopus 로고    scopus 로고
    • Leptin suppresses semi-starvation induced hyperactivity in rats: Implications for anorexia nervosa
    • Exner, C. et al. Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa. Mol. Psychiatry 5, 476-481 (2000).
    • (2000) Mol. Psychiatry , vol.5 , pp. 476-481
    • Exner, C.1
  • 90
    • 9844268513 scopus 로고    scopus 로고
    • Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration
    • Hebebrand, J. et al. Leptin levels in patients with anorexia nervosa are reduced in the acute stage and elevated upon short-term weight restoration. Mol. Psychiatry 2, 330-334 (1997).
    • (1997) Mol. Psychiatry , vol.2 , pp. 330-334
    • Hebebrand, J.1
  • 91
    • 0038727492 scopus 로고    scopus 로고
    • The effect of therapeutically induced weight gain on plasma leptin levels in patients with anorexia nervosa
    • Holtkamp, K. et al. The effect of therapeutically induced weight gain on plasma leptin levels in patients with anorexia nervosa. J. Psychiatr. Res. 37, 165-169 (2003).
    • (2003) J. Psychiatr. Res. , vol.37 , pp. 165-169
    • Holtkamp, K.1
  • 92
    • 34347254669 scopus 로고    scopus 로고
    • Relationships between serum adipokines, insulin levels, and bone density in girls with anorexia nervosa
    • Misra, M. et al. Relationships between serum adipokines, insulin levels, and bone density in girls with anorexia nervosa. J. Clin. Endocrinol. Metab. 92, 2046-2052 (2007).
    • (2007) J. Clin. Endocrinol. Metab. , vol.92 , pp. 2046-2052
    • Misra, M.1
  • 93
    • 0038021505 scopus 로고    scopus 로고
    • Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism
    • Pannacciulli, N. et al. Anorexia nervosa is characterized by increased adiponectin plasma levels and reduced nonoxidative glucose metabolism. J. Clin. Endocrinol. Metab. 88, 1748-1752 (2003).
    • (2003) J. Clin. Endocrinol. Metab. , vol.88 , pp. 1748-1752
    • Pannacciulli, N.1
  • 94
    • 15944402473 scopus 로고    scopus 로고
    • Serum adiponectin and resistin concentrations in patients with restrictive and binge/purge form of anorexia nervosa and bulimia nervosa
    • Housova, J. et al. Serum adiponectin and resistin concentrations in patients with restrictive and binge/purge form of anorexia nervosa and bulimia nervosa. J. Clin. Endocrinol. Metab. 90, 1366-1370 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 1366-1370
    • Housova, J.1
  • 95
    • 1942472937 scopus 로고    scopus 로고
    • Adiponectin in anorexia nervosa and bulimia nervosa
    • Tagami, T. et al. Adiponectin in anorexia nervosa and bulimia nervosa. J. Clin. Endocrinol. Metab. 89, 1833-1837 (2004).
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 1833-1837
    • Tagami, T.1
  • 96
    • 84870817721 scopus 로고    scopus 로고
    • The role of adiponectin multimers in anorexia nervosa
    • Amitani, H. et al. The role of adiponectin multimers in anorexia nervosa. Nutrition 29, 203-206 (2013).
    • (2013) Nutrition , vol.29 , pp. 203-206
    • Amitani, H.1
  • 99
    • 13444265857 scopus 로고    scopus 로고
    • Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa
    • Otto, B. et al. Weight gain decreases elevated plasma ghrelin concentrations of patients with anorexia nervosa. Eur. J. Endocrinol. 145, 669-673 (2001).
    • (2001) Eur. J. Endocrinol. , vol.145 , pp. 669-673
    • Otto, B.1
  • 100
    • 84866262428 scopus 로고    scopus 로고
    • Therapeutic potential of ghrelin in restricting-type anorexia nervosa
    • Hotta, M., Ohwada, R., Akamizu, T., Shibasaki, T. & Kangawa, K. Therapeutic potential of ghrelin in restricting-type anorexia nervosa. Meth. Enzymol. 514, 381-398 (2012).
    • (2012) Meth. Enzymol. , vol.514 , pp. 381-398
    • Hotta, M.1    Ohwada, R.2    Akamizu, T.3    Shibasaki, T.4    Kangawa, K.5
  • 101
    • 75149130596 scopus 로고    scopus 로고
    • Increased suppression of serum ghrelin concentration by hyperinsulinemia in women with anorexia nervosa
    • Karczewska-Kupczewska, M. et al. Increased suppression of serum ghrelin concentration by hyperinsulinemia in women with anorexia nervosa. Eur. J. Endocrinol. 162, 235-239 (2010).
    • (2010) Eur. J. Endocrinol. , vol.162 , pp. 235-239
    • Karczewska-Kupczewska, M.1
  • 102
    • 33644824823 scopus 로고    scopus 로고
    • Elevated peptide YY levels in adolescent girls with anorexia nervosa
    • Misra, M. et al. Elevated peptide YY levels in adolescent girls with anorexia nervosa. J. Clin. Endocrinol. Metab. 91, 1027-1033 (2006).
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 1027-1033
    • Misra, M.1
  • 103
    • 44949152383 scopus 로고    scopus 로고
    • Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosa
    • Utz, A. L. et al. Peptide YY (PYY) levels and bone mineral density (BMD) in women with anorexia nervosa. Bone 43, 135-139 (2008).
    • (2008) Bone , vol.43 , pp. 135-139
    • Utz, A.L.1
  • 104
    • 78751497299 scopus 로고    scopus 로고
    • Appetite-regulating hormones cortisol and peptide YY are associated with disordered eating psychopathology, independent of body mass index
    • Lawson, E. et al. Appetite-regulating hormones cortisol and peptide YY are associated with disordered eating psychopathology, independent of body mass index. Eur. J. Endocrinol. 164, 253-261 (2011).
    • (2011) Eur. J. Endocrinol. , vol.164 , pp. 253-261
    • Lawson, E.1
  • 105
    • 34247846295 scopus 로고    scopus 로고
    • Incomplete restoration of the secretion of ghrelin and PYY compared to insulin after food ingestion following weight gain in anorexia nervosa
    • Nakahara, T. et al. Incomplete restoration of the secretion of ghrelin and PYY compared to insulin after food ingestion following weight gain in anorexia nervosa. J. Psychiatr. Res. 41, 814-820 (2007).
    • (2007) J. Psychiatr. Res. , vol.41 , pp. 814-820
    • Nakahara, T.1
  • 106
    • 16644391441 scopus 로고    scopus 로고
    • Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls
    • Misra, M. et al. Effects of anorexia nervosa on clinical, hematologic, biochemical, and bone density parameters in community-dwelling adolescent girls. Pediatrics 114, 1574-1583 (2004).
    • (2004) Pediatrics , vol.114 , pp. 1574-1583
    • Misra, M.1
  • 107
    • 84877688157 scopus 로고    scopus 로고
    • Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius
    • Faje, A. T. et al. Adolescent girls with anorexia nervosa have impaired cortical and trabecular microarchitecture and lower estimated bone strength at the distal radius. J. Clin. Endocrinol. Metab. 98, 1923-1929 (2013).
    • (2013) J. Clin. Endocrinol. Metab. , vol.98 , pp. 1923-1929
    • Faje, A.T.1
  • 108
    • 74449090527 scopus 로고    scopus 로고
    • Hormone predictors of abnormal bone microarchitecture in women with anorexia nervosa
    • Lawson, E. A. et al. Hormone predictors of abnormal bone microarchitecture in women with anorexia nervosa. Bone 46, 458-463 (2010).
    • (2010) Bone , vol.46 , pp. 458-463
    • Lawson, E.A.1
  • 109
    • 77957349833 scopus 로고    scopus 로고
    • Women with anorexia nervosa: Finite element and trabecular structure analysis by using flat-panel volume CT
    • Walsh, C. J. et al. Women with anorexia nervosa: finite element and trabecular structure analysis by using flat-panel volume CT. Radiology 257, 167-174 (2010).
    • (2010) Radiology , vol.257 , pp. 167-174
    • Walsh, C.J.1
  • 110
    • 0026030364 scopus 로고
    • The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass
    • Rigotti, N. A., Neer, R. M., Skates, S. J., Herzog, D. B. & Nussbaum, S. R. The clinical course of osteoporosis in anorexia nervosa. A longitudinal study of cortical bone mass. JAMA 265, 1133-1138 (1991).
    • (1991) JAMA , vol.265 , pp. 1133-1138
    • Rigotti, N.A.1    Neer, R.M.2    Skates, S.J.3    Herzog, D.B.4    Nussbaum, S.R.5
  • 111
    • 84954289531 scopus 로고    scopus 로고
    • Bone mineral density, osteoporosis, and fractures among people with eating disorders: A systematic review and meta-analysis
    • Solmi, M. et al. Bone mineral density, osteoporosis, and fractures among people with eating disorders: a systematic review and meta-analysis. Acta Psychiatr. Scand. 133, 341-351(2016).
    • (2016) Acta Psychiatr. Scand. , vol.133 , pp. 341-351
    • Solmi, M.1
  • 112
    • 84902374545 scopus 로고    scopus 로고
    • Fracture risk and areal bone mineral density in adolescent females with anorexia nervosa
    • Faje, A. T. et al. Fracture risk and areal bone mineral density in adolescent females with anorexia nervosa. Int. J. Eat. Disord. 47, 458-466 (2014).
    • (2014) Int. J. Eat. Disord. , vol.47 , pp. 458-466
    • Faje, A.T.1
  • 113
    • 63249083581 scopus 로고    scopus 로고
    • Trabecular structure analysis of the distal radius in adolescent patients with anorexia nervosa using ultra high resolution flat panel based volume CT
    • Bredella, M. A., Misra, M., Miller, K. K., Klibanski, A. & Gupta, R. Trabecular structure analysis of the distal radius in adolescent patients with anorexia nervosa using ultra high resolution flat panel based volume CT. J. Musculoskelet. Neuronal Interact. 8, 315 (2008).
    • (2008) J. Musculoskelet. Neuronal Interact. , vol.8 , pp. 315
    • Bredella, M.A.1    Misra, M.2    Miller, K.K.3    Klibanski, A.4    Gupta, R.5
  • 114
    • 0036065338 scopus 로고    scopus 로고
    • Bone metabolism markers and bone mass in healthy pubertal boys and girls
    • Van Coeverden, S. C. et al. Bone metabolism markers and bone mass in healthy pubertal boys and girls. Clin. Endocrinol. (Oxf.) 57, 107-116 (2002).
    • (2002) Clin. Endocrinol. (Oxf.) , vol.57 , pp. 107-116
    • Van Coeverden, S.C.1
  • 115
    • 0036738484 scopus 로고    scopus 로고
    • Abnormal bone mineral accrual in adolescent girls with anorexia nervosa
    • Soyka, L. A. et al. Abnormal bone mineral accrual in adolescent girls with anorexia nervosa. J. Clin. Endocrinol. Metab. 87, 4177-4185 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4177-4185
    • Soyka, L.A.1
  • 116
    • 85013306268 scopus 로고    scopus 로고
    • Medical complications of anorexia nervosa and bulimia
    • Westmoreland, P., Krantz, M. J. & Mehler, P. S. Medical complications of anorexia nervosa and bulimia. Am. J. Med. 129, 30-37 (2016).
    • (2016) Am. J. Med. , vol.129 , pp. 30-37
    • Westmoreland, P.1    Krantz, M.J.2    Mehler, P.S.3
  • 118
    • 0034700316 scopus 로고    scopus 로고
    • Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa
    • Grinspoon, S. et al. Prevalence and predictive factors for regional osteopenia in women with anorexia nervosa. Ann. Intern. Med. 133, 790-794 (2000).
    • (2000) Ann. Intern. Med. , vol.133 , pp. 790-794
    • Grinspoon, S.1
  • 119
    • 33747628468 scopus 로고    scopus 로고
    • Determinants of skeletal loss and recovery in anorexia nervosa
    • Miller, K. K. et al. Determinants of skeletal loss and recovery in anorexia nervosa. J. Clin. Endocrinol. Metab. 91, 2931-2937 (2006).
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 2931-2937
    • Miller, K.K.1
  • 120
    • 19044377826 scopus 로고    scopus 로고
    • Bone marrow changes in anorexia nervosa are correlated with the amount of weight loss and not with other clinical findings
    • Abella, E. et al. Bone marrow changes in anorexia nervosa are correlated with the amount of weight loss and not with other clinical findings. Am. J. Clin. Pathol. 118, 582-588 (2002).
    • (2002) Am. J. Clin. Pathol. , vol.118 , pp. 582-588
    • Abella, E.1
  • 121
    • 66749120025 scopus 로고    scopus 로고
    • Increased bone marrow fat in anorexia nervosa
    • Bredella, M. A. et al. Increased bone marrow fat in anorexia nervosa. J. Clin. Endocrinol. Metab. 94, 2129-2136 (2009).
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 2129-2136
    • Bredella, M.A.1
  • 122
    • 75149113977 scopus 로고    scopus 로고
    • Preadipocyte factor-1 is associated with marrow adiposity and bone mineral density in women with anorexia nervosa
    • Fazeli, P. K. et al. Preadipocyte factor-1 is associated with marrow adiposity and bone mineral density in women with anorexia nervosa. J. Clin. Endocrinol. Metab. 95, 407-413 (2010).
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , pp. 407-413
    • Fazeli, P.K.1
  • 123
    • 84864799320 scopus 로고    scopus 로고
    • Marrow fat and preadipocyte factor-1 levels decrease with recovery in women with anorexia nervosa
    • Fazeli, P. K. et al. Marrow fat and preadipocyte factor-1 levels decrease with recovery in women with anorexia nervosa. J. Bone Miner. Res. 27, 1864-1871 (2012).
    • (2012) J. Bone Miner. Res. , vol.27 , pp. 1864-1871
    • Fazeli, P.K.1
  • 125
    • 33751501004 scopus 로고    scopus 로고
    • Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density
    • Jia, D., O'Brien, C. A., Stewart, S. A., Manolagas, S. C. & Weinstein, R. S. Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density. Endocrinology 147, 5592-5599 (2006).
    • (2006) Endocrinology , vol.147 , pp. 5592-5599
    • Jia, D.1    O'Brien, C.A.2    Stewart, S.A.3    Manolagas, S.C.4    Weinstein, R.S.5
  • 126
    • 0033690895 scopus 로고    scopus 로고
    • The mechanisms of estrogen regulation of bone resorption
    • Riggs, B. L. The mechanisms of estrogen regulation of bone resorption. J. Clin. Invest. 106, 1203-1204 (2000).
    • (2000) J. Clin. Invest. , vol.106 , pp. 1203-1204
    • Riggs, B.L.1
  • 127
    • 78650955673 scopus 로고    scopus 로고
    • Regulation of circulating sclerostin levels by sex steroids in women and in men
    • Mfdder, U. I. et al. Regulation of circulating sclerostin levels by sex steroids in women and in men. J. Bone Miner. Res. 26, 27-34 (2011).
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 27-34
    • Mfdder, U.I.1
  • 128
    • 61349144964 scopus 로고    scopus 로고
    • Androgens and bone
    • Clarke, B. L. & Khosla, S. Androgens and bone. Steroids 74, 296-305 (2009).
    • (2009) Steroids , vol.74 , pp. 296-305
    • Clarke, B.L.1    Khosla, S.2
  • 129
    • 0024581104 scopus 로고
    • Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa
    • Biller, B. et al. Mechanisms of osteoporosis in adult and adolescent women with anorexia nervosa. J. Clin. Endocrinol. Metab. 68, 548-554 (1989).
    • (1989) J. Clin. Endocrinol. Metab. , vol.68 , pp. 548-554
    • Biller, B.1
  • 130
    • 84869221877 scopus 로고    scopus 로고
    • Plasma sodium level is associated with bone loss severity in women with anorexia nervosa: A cross-sectional study
    • Lawson, E. A. et al. Plasma sodium level is associated with bone loss severity in women with anorexia nervosa: a cross-sectional study. J. Clin. Psychiatry 73, e1379-e1383 (2012).
    • (2012) J. Clin. Psychiatry , vol.73 , pp. e1379-e1383
    • Lawson, E.A.1
  • 131
    • 77953437686 scopus 로고    scopus 로고
    • Hyponatremia-induced osteoporosis
    • Verbalis, J. G. et al. Hyponatremia-induced osteoporosis. J. Bone Miner. Res. 25, 554-563 (2010).
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 554-563
    • Verbalis, J.G.1
  • 132
    • 84953211759 scopus 로고    scopus 로고
    • Functions of vasopressin and oxytocin in bone mass regulation
    • Sun, L. et al. Functions of vasopressin and oxytocin in bone mass regulation. Proc. Natl Acad. Sci. USA 113, 164-169 (2016).
    • (2016) Proc. Natl Acad. Sci. USA , vol.113 , pp. 164-169
    • Sun, L.1
  • 133
    • 0036847619 scopus 로고    scopus 로고
    • Leptin regulates bone formation via the sympathetic nervous system
    • Takeda, S. et al. Leptin regulates bone formation via the sympathetic nervous system. Cell 111, 305-317 (2002).
    • (2002) Cell , vol.111 , pp. 305-317
    • Takeda, S.1
  • 134
    • 18744376564 scopus 로고    scopus 로고
    • Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo
    • Cornish, J. et al. Leptin directly regulates bone cell function in vitro and reduces bone fragility in vivo. J. Endocrinol. 175, 405-415 (2002).
    • (2002) J. Endocrinol. , vol.175 , pp. 405-415
    • Cornish, J.1
  • 135
    • 1542316258 scopus 로고    scopus 로고
    • Leptin deficiency produces contrasting phenotypes in bones of the limb and spine
    • Hamrick, M. W., Pennington, C., Newton, D., Xie, D. & Isales, C. Leptin deficiency produces contrasting phenotypes in bones of the limb and spine. Bone 34, 376-383 (2004).
    • (2004) Bone , vol.34 , pp. 376-383
    • Hamrick, M.W.1    Pennington, C.2    Newton, D.3    Xie, D.4    Isales, C.5
  • 136
    • 18044394024 scopus 로고    scopus 로고
    • Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast
    • Oshima, K. et al. Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast. Biochem. Biophys. Res. Commun. 331, 520-526 (2005).
    • (2005) Biochem. Biophys. Res. Commun. , vol.331 , pp. 520-526
    • Oshima, K.1
  • 137
    • 33748079106 scopus 로고    scopus 로고
    • Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways
    • Shinoda, Y. et al. Regulation of bone formation by adiponectin through autocrine/paracrine and endocrine pathways. J. Cell. Biochem. 99, 196-208 (2006).
    • (2006) J. Cell. Biochem. , vol.99 , pp. 196-208
    • Shinoda, Y.1
  • 138
    • 84863655029 scopus 로고    scopus 로고
    • Peptide YY regulates bone remodeling in mice: A link between gut and skeletal biology
    • Wong, I. P. L. et al. Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology. PLoS ONE 7, e40038 (2012).
    • (2012) PLoS ONE , vol.7
    • Wong, I.P.L.1
  • 139
    • 0028923621 scopus 로고
    • The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa
    • Klibanski, A., Biller, B. M., Schoenfeld, D. A., Herzog, D. B. & Saxe, V. C. The effects of estrogen administration on trabecular bone loss in young women with anorexia nervosa. J. Clin. Endocrinol. Metab. 80, 898-904 (1995).
    • (1995) J. Clin. Endocrinol. Metab. , vol.80 , pp. 898-904
    • Klibanski, A.1    Biller, B.M.2    Schoenfeld, D.A.3    Herzog, D.B.4    Saxe, V.C.5
  • 140
    • 33751006766 scopus 로고    scopus 로고
    • Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: A double-blind, placebo-controlled study
    • Strokosch, G. R., Friedman, A. J., Wu, S.-C. & Kamin, M. Effects of an oral contraceptive (norgestimate/ethinyl estradiol) on bone mineral density in adolescent females with anorexia nervosa: a double-blind, placebo-controlled study. J. Adolesc. Health 39, 819-827 (2006).
    • (2006) J. Adolesc. Health , vol.39 , pp. 819-827
    • Strokosch, G.R.1    Friedman, A.J.2    Wu, S.-C.3    Kamin, M.4
  • 141
    • 0036328224 scopus 로고    scopus 로고
    • The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa
    • Golden, N. H. et al. The effect of estrogen-progestin treatment on bone mineral density in anorexia nervosa. J. Pediatr. Adolesc. Gynecol. 15, 135-143 (2002).
    • (2002) J. Pediatr. Adolesc. Gynecol. , vol.15 , pp. 135-143
    • Golden, N.H.1
  • 142
    • 0025882208 scopus 로고
    • Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women
    • Weissberger, A. J., Ho, K. K. & Lazarus, L. Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-hour growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J. Clin. Endocrinol. Metab. 72, 374-381 (1991).
    • (1991) J. Clin. Endocrinol. Metab. , vol.72 , pp. 374-381
    • Weissberger, A.J.1    Ho, K.K.2    Lazarus, L.3
  • 143
    • 80053190215 scopus 로고    scopus 로고
    • Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa
    • Misra, M. et al. Physiologic estrogen replacement increases bone density in adolescent girls with anorexia nervosa. J. Bone Miner. Res. 26, 2430-2438 (2011).
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 2430-2438
    • Misra, M.1
  • 144
    • 79960082236 scopus 로고    scopus 로고
    • Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: A randomized, placebo-controlled study
    • Miller, K. K. et al. Effects of risedronate and low-dose transdermal testosterone on bone mineral density in women with anorexia nervosa: a randomized, placebo-controlled study. J. Clin. Endocrinol. Metab. 96, 2081-2088 (2011).
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 2081-2088
    • Miller, K.K.1
  • 145
    • 0036845474 scopus 로고    scopus 로고
    • Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: A randomized trial
    • Gordon, C. M. et al. Effects of oral dehydroepiandrosterone on bone density in young women with anorexia nervosa: a randomized trial. J. Clin. Endocrinol. Metab. 87, 4935-4941 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 4935-4941
    • Gordon, C.M.1
  • 146
    • 84862152500 scopus 로고    scopus 로고
    • The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa
    • Divasta, A. D. et al. The effect of gonadal and adrenal steroid therapy on skeletal health in adolescents and young women with anorexia nervosa. Metab. Clin. Exp. 61, 1010-1020 (2012).
    • (2012) Metab. Clin. Exp. , vol.61 , pp. 1010-1020
    • Divasta, A.D.1
  • 147
    • 0036078286 scopus 로고    scopus 로고
    • Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa
    • Grinspoon, S., Thomas, L., Miller, K., Herzog, D. & Klibanski, A. Effects of recombinant human IGF-I and oral contraceptive administration on bone density in anorexia nervosa. J. Clin. Endocrinol. Metab. 87, 2883-2891 (2002).
    • (2002) J. Clin. Endocrinol. Metab. , vol.87 , pp. 2883-2891
    • Grinspoon, S.1    Thomas, L.2    Miller, K.3    Herzog, D.4    Klibanski, A.5
  • 148
    • 67949084970 scopus 로고    scopus 로고
    • Effects of rhIGF-1 administration on surrogate markers of bone turnover in adolescents with anorexia nervosa
    • Misra, M. et al. Effects of rhIGF-1 administration on surrogate markers of bone turnover in adolescents with anorexia nervosa. Bone 45, 493-498 (2009).
    • (2009) Bone , vol.45 , pp. 493-498
    • Misra, M.1
  • 149
    • 21244503177 scopus 로고    scopus 로고
    • Alendronate for the treatment of osteopenia in anorexia nervosa: A randomized, double-blind, placebo-controlled trial
    • Golden, N. H. et al. Alendronate for the treatment of osteopenia in anorexia nervosa: a randomized, double-blind, placebo-controlled trial. J. Clin. Endocrinol. Metab. 90, 3179-3185 (2005).
    • (2005) J. Clin. Endocrinol. Metab. , vol.90 , pp. 3179-3185
    • Golden, N.H.1
  • 150
    • 84855517874 scopus 로고    scopus 로고
    • The use of bisphosphonates in women prior to or during pregnancy and lactation
    • Stathopoulos, I. P. et al. The use of bisphosphonates in women prior to or during pregnancy and lactation. Hormones (Athens) 10, 280-291 (2011).
    • (2011) Hormones (Athens) , vol.10 , pp. 280-291
    • Stathopoulos, I.P.1
  • 151
    • 84898460378 scopus 로고    scopus 로고
    • Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa
    • Fazeli, P. K. et al. Teriparatide increases bone formation and bone mineral density in adult women with anorexia nervosa. J. Clin. Endocrinol. Metab. 99, 1322-1329 (2014).
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. 1322-1329
    • Fazeli, P.K.1
  • 152
    • 0036001310 scopus 로고    scopus 로고
    • Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety
    • Vahle, J. L. et al. Skeletal changes in rats given daily subcutaneous injections of recombinant human parathyroid hormone (1-34) for 2 years and relevance to human safety. Toxicol. Pathol. 30, 312-321 (2002).
    • (2002) Toxicol. Pathol. , vol.30 , pp. 312-321
    • Vahle, J.L.1
  • 153
    • 85012070857 scopus 로고    scopus 로고
    • US Department of Health and Human Services. Food and Drug Administration. Center for Drug Evaluation and Research (CDER). Guidance for industry. Development of parathyroid hormone for the prevention and treatment of osteoporosis. Draft guidance. FDA
    • US Department of Health and Human Services. Food and Drug Administration. Center for Drug Evaluation and Research (CDER). Guidance for industry. Development of parathyroid hormone for the prevention and treatment of osteoporosis. Draft guidance. FDA http://www.fda.gov/OHRMS/DOCKETS/98fr/001307gd.pdf (2000).
    • (2000)
  • 154
    • 0027174314 scopus 로고
    • Outcome of bone mineral density in anorexia nervosa patients 11.7 years after first admission
    • Herzog, W. et al. Outcome of bone mineral density in anorexia nervosa patients 11.7 years after first admission. J. Bone Miner. Res. 8, 597-605 (1993).
    • (1993) J. Bone Miner. Res. , vol.8 , pp. 597-605
    • Herzog, W.1
  • 155
    • 0034032159 scopus 로고    scopus 로고
    • Bone density of women who have recovered from anorexia nervosa
    • Hartman, D. et al. Bone density of women who have recovered from anorexia nervosa. Int. J. Eat. Disord. 28, 107-112 (2000).
    • (2000) Int. J. Eat. Disord. , vol.28 , pp. 107-112
    • Hartman, D.1
  • 156
    • 84939210500 scopus 로고    scopus 로고
    • Reduced bone strength and muscle force in women 27 years after anorexia nervosa
    • Mueller, S. M. et al. Reduced bone strength and muscle force in women 27 years after anorexia nervosa. J. Clin. Endocrinol. Metab. 100, 2927-2933 (2015).
    • (2015) J. Clin. Endocrinol. Metab. , vol.100 , pp. 2927-2933
    • Mueller, S.M.1
  • 157
    • 33750631611 scopus 로고    scopus 로고
    • Nutrient intake in community-dwelling adolescent girls with anorexia nervosa and in healthy adolescents
    • Misra, M. et al. Nutrient intake in community-dwelling adolescent girls with anorexia nervosa and in healthy adolescents. Am. J. Clin. Nutr. 84, 698-706 (2006).
    • (2006) Am. J. Clin. Nutr. , vol.84 , pp. 698-706
    • Misra, M.1
  • 158
    • 38849093291 scopus 로고    scopus 로고
    • Low prevalence of Vitamin D deficiency among adolescents with anorexia nervosa
    • Haagensen, A. L., Feldman, H. A., Ringelheim, J. & Gordon, C. M. Low prevalence of vitamin D deficiency among adolescents with anorexia nervosa. Osteoporos. Int. 19, 289-294 (2008).
    • (2008) Osteoporos. Int. , vol.19 , pp. 289-294
    • Haagensen, A.L.1    Feldman, H.A.2    Ringelheim, J.3    Gordon, C.M.4
  • 160
    • 34347366102 scopus 로고    scopus 로고
    • Androgen deficiency: Association with increased anxiety and depression symptom severity in anorexia nervosa
    • Miller, K. K. et al. Androgen deficiency: association with increased anxiety and depression symptom severity in anorexia nervosa. J. Clin. Psychiatry 68, 959-965 (2007).
    • (2007) J. Clin. Psychiatry , vol.68 , pp. 959-965
    • Miller, K.K.1
  • 161
    • 12344334398 scopus 로고    scopus 로고
    • Novel actions of estrogen receptor-β on anxiety-related behaviors
    • Lund, T. D., Rovis, T., Chung, W. C. J. & Handa, R. J. Novel actions of estrogen receptor-β on anxiety-related behaviors. Endocrinology 146, 797-807 (2005).
    • (2005) Endocrinology , vol.146 , pp. 797-807
    • Lund, T.D.1    Rovis, T.2    Chung, W.C.J.3    Handa, R.J.4
  • 162
    • 84857836228 scopus 로고    scopus 로고
    • Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat
    • Lawson, E. et al. Leptin levels are associated with decreased depressive symptoms in women across the weight spectrum, independent of body fat. Clin. Endocrinol. (Oxf.) 76, 520-525 (2012).
    • (2012) Clin. Endocrinol. (Oxf.) , vol.76 , pp. 520-525
    • Lawson, E.1
  • 163
  • 164
    • 84155164725 scopus 로고    scopus 로고
    • Behavioral effects of estradiol therapy in ovariectomized rats depend on the age when the treatment is initiated
    • Diz-Chaves, Y. et al. Behavioral effects of estradiol therapy in ovariectomized rats depend on the age when the treatment is initiated. Exp. Gerontol. 47, 93-99 (2012).
    • (2012) Exp. Gerontol. , vol.47 , pp. 93-99
    • Diz-Chaves, Y.1
  • 165
    • 70350534256 scopus 로고    scopus 로고
    • Estrous cycle phase and gonadal hormones influence conditioned fear extinction
    • Milad, M. R., Igoe, S. A., Lebron-Milad, K. & Novales, J. E. Estrous cycle phase and gonadal hormones influence conditioned fear extinction. Neuroscience 164, 887-895 (2009).
    • (2009) Neuroscience , vol.164 , pp. 887-895
    • Milad, M.R.1    Igoe, S.A.2    Lebron-Milad, K.3    Novales, J.E.4
  • 166
    • 0742270551 scopus 로고    scopus 로고
    • Increased incidence of diagnosed depressive illness in hypogonadal older men
    • Shores, M. M. et al. Increased incidence of diagnosed depressive illness in hypogonadal older men. Arch. Gen. Psychiatry 61, 162-167 (2004).
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 162-167
    • Shores, M.M.1
  • 167
    • 84867252694 scopus 로고    scopus 로고
    • Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa
    • Lawson, E. A. et al. Oxytocin secretion is associated with severity of disordered eating psychopathology and insular cortex hypoactivation in anorexia nervosa. J. Clin. Endocrinol. Metab. 97, E1898-E1908 (2012).
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , pp. E1898-E1908
    • Lawson, E.A.1
  • 168
    • 49849094202 scopus 로고    scopus 로고
    • Cognitive function and brain structure in females with a history of adolescent-onset anorexia nervosa
    • Chui, H. T. et al. Cognitive function and brain structure in females with a history of adolescent-onset anorexia nervosa. Pediatrics 122, e426-e437 (2008).
    • (2008) Pediatrics , vol.122 , pp. e426-e437
    • Chui, H.T.1
  • 169
    • 84883173374 scopus 로고    scopus 로고
    • Impact of physiologic estrogen replacement on anxiety symptoms, body shape perception, and eating attitudes in adolescent girls with anorexia nervosa: Data from a randomized controlled trial
    • Misra, M. et al. Impact of physiologic estrogen replacement on anxiety symptoms, body shape perception, and eating attitudes in adolescent girls with anorexia nervosa: data from a randomized controlled trial. J. Clin. Psychiatry 74, e765-e771 (2013).
    • (2013) J. Clin. Psychiatry , vol.74 , pp. e765-e771
    • Misra, M.1
  • 170
    • 33646391524 scopus 로고    scopus 로고
    • Effects of testosterone replacement in androgen-deficient women with hypopituitarism: A randomized, double-blind, placebo-controlled study
    • Miller, K. K. et al. Effects of testosterone replacement in androgen-deficient women with hypopituitarism: a randomized, double-blind, placebo-controlled study. J. Clin. Endocrinol. Metab. 91, 1683-1690 (2006).
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 1683-1690
    • Miller, K.K.1
  • 171
    • 77749264383 scopus 로고    scopus 로고
    • Low-dose transdermal testosterone augmentation therapy improves depression severity in women
    • Miller, K. K. et al. Low-dose transdermal testosterone augmentation therapy improves depression severity in women. CNS Spectr. 14, 688-694 (2009).
    • (2009) CNS Spectr. , vol.14 , pp. 688-694
    • Miller, K.K.1
  • 172
    • 0034618866 scopus 로고    scopus 로고
    • Transdermal testosterone treatment in women with impaired sexual function after oophorectomy
    • Shifren, J. L. et al. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. N. Engl. J. Med. 343, 682-688 (2000).
    • (2000) N. Engl. J. Med. , vol.343 , pp. 682-688
    • Shifren, J.L.1
  • 173
    • 49249123988 scopus 로고    scopus 로고
    • Bone metabolism in adolescent boys with anorexia nervosa
    • Misra, M. et al. Bone metabolism in adolescent boys with anorexia nervosa. J. Clin. Endocrinol. Metab. 93, 3029-3036 (2008).
    • (2008) J. Clin. Endocrinol. Metab. , vol.93 , pp. 3029-3036
    • Misra, M.1
  • 174
    • 57449113477 scopus 로고    scopus 로고
    • Percentage extremity fat, but not percentage trunk fat, is lower in adolescent boys with anorexia nervosa than in healthy adolescents
    • Misra, M. et al. Percentage extremity fat, but not percentage trunk fat, is lower in adolescent boys with anorexia nervosa than in healthy adolescents. Am. J. Clin. Nutr. 88, 1478-1484 (2008).
    • (2008) Am. J. Clin. Nutr. , vol.88 , pp. 1478-1484
    • Misra, M.1
  • 175
    • 33745684473 scopus 로고    scopus 로고
    • Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes
    • Kapoor, D., Goodwin, E., Channer, K. S. & Jones, T. H. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes. Eur. J. Endocrinol. 154, 899-906 (2006).
    • (2006) Eur. J. Endocrinol. , vol.154 , pp. 899-906
    • Kapoor, D.1    Goodwin, E.2    Channer, K.S.3    Jones, T.H.4
  • 176
    • 0031882392 scopus 로고    scopus 로고
    • Using quantitative CT to assess adipose distribution in adult men with acquired hypogonadism
    • Katznelson, L. et al. Using quantitative CT to assess adipose distribution in adult men with acquired hypogonadism. AJR Am. J. Roentgenol. 170, 423-427 (1998).
    • (1998) AJR Am. J. Roentgenol. , vol.170 , pp. 423-427
    • Katznelson, L.1
  • 177
    • 0029838823 scopus 로고    scopus 로고
    • Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism
    • Katznelson, L. et al. Increase in bone density and lean body mass during testosterone administration in men with acquired hypogonadism. J. Clin. Endocrinol. Metab. 81, 4358-4365 (1996).
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 4358-4365
    • Katznelson, L.1
  • 178
    • 0034920213 scopus 로고    scopus 로고
    • Serum leptin, gonadotropin, and testosterone concentrations in male patients with anorexia nervosa during weight gain
    • Wabitsch, M. et al. Serum leptin, gonadotropin, and testosterone concentrations in male patients with anorexia nervosa during weight gain. J. Clin. Endocrinol. Metab. 86, 2982-2988 (2001).
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 2982-2988
    • Wabitsch, M.1
  • 179
    • 0022578149 scopus 로고
    • Osteopenia and bone fractures in a man with anorexia nervosa and hypogonadism
    • Rigotti, N. A., Neer, R. M. & Jameson, L. Osteopenia and bone fractures in a man with anorexia nervosa and hypogonadism. JAMA 256, 385-388 (1986).
    • (1986) JAMA , vol.256 , pp. 385-388
    • Rigotti, N.A.1    Neer, R.M.2    Jameson, L.3
  • 180
    • 0033947461 scopus 로고    scopus 로고
    • Stress fracture of the inferior and superior pubic ramus in a man with anorexia nervosa and hypogonadism
    • Thienpont, E., Bellemans, J., Samson, I. & Fabry, G. Stress fracture of the inferior and superior pubic ramus in a man with anorexia nervosa and hypogonadism. Acta Orthop. Belg. 66, 297-301 (2000).
    • (2000) Acta Orthop. Belg. , vol.66 , pp. 297-301
    • Thienpont, E.1    Bellemans, J.2    Samson, I.3    Fabry, G.4
  • 182
    • 33747787014 scopus 로고    scopus 로고
    • Bone mineral density in bulimic women - Influence of endocrine factors and previous anorexia
    • Naesson, S., Carlstrfm, K., Glant, R., Jacobsson, H. & Hirschberg, A. L. Bone mineral density in bulimic women - influence of endocrine factors and previous anorexia. Eur. J. Endocrinol. 155, 245-251 (2006).
    • (2006) Eur. J. Endocrinol. , vol.155 , pp. 245-251
    • Naesson, S.1    Carlstrfm, K.2    Glant, R.3    Jacobsson, H.4    Hirschberg, A.L.5
  • 183
    • 84994376755 scopus 로고    scopus 로고
    • Bone density, body composition, and psychopathology of anorexia nervosa spectrum disorders in DSM-IV versus DSM-5
    • Schorr, M. et al. Bone density, body composition, and psychopathology of anorexia nervosa spectrum disorders in DSM-IV versus DSM-5. Int. J. Eat. Dis. http://dx.doi.org/10.1002/eat.22603 (2016).
    • (2016) Int. J. Eat. Dis.
    • Schorr, M.1


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