The mechanisms of estrogen regulation of bone resorption

Journal of Clinical Investigation

Volumn 106, Issue 10, 2000, Pages 1203-1204

  Riggs, B L ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; ESTROGEN; ESTROGEN RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 1; INTERLEUKIN 6; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ESTROGEN ACTIVITY; HUMAN; METABOLIC REGULATION; NONHUMAN; NOTE; OSTEOCLAST; OSTEOLYSIS; OSTEOPOROSIS; PRIORITY JOURNAL;

EID: 0033690895     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI11468     Document Type: Note

References (10)

1. A unitary model for involutional osteoporosis: Estrogen deficiency causes both type I and type II osreoporosis in postmenopausal women and contributes to bone loss in aging men
2. Birth and death of bone cells: Basic regulatory mechanisms and implications for the pathogenesis and treatment of osteopotosis
3. Estrogen, cytokines, and pathogenesis of postmenopausal osteoporosis
4. Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand families
5. The roles of osteoproregerin and osteoprotegerin ligand in the paracrine regulation of bone resorption
6. Estrogens suppress RANK ligand-induced osteoclast differentiation via a stromal cell independent mechanism involving c-Jun repression
7. Estrogen deficiency induces bone loss by enhancing T cell production of TNFα
8. Simultaneous block of interleukin-1 and tumor necrosis factor is required to completely prevent bone loss in the early postovariectomy period
9. Endogenous bone-resorbing factors in estrogen deficiency: Cooperative effects of IL-1 and IL-6
10. Interleukin-6 expression and histomorphometry of bones from mice deficient in receptors for interleukin-1 or tumor necrosis factor