Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis

Journal of Clinical Endocrinology and Metabolism

Volumn 94, Issue 11, 2009, Pages 4315-4323

  Jayasena, Channa N ^a   Nijher, Gurjinder M K ^a   Chaudhri, Owais B ^a   Murphy, Kevin G ^a   Ranger, Amita ^a   Lim, Adrian ^b   Patel, Daksha ^b   Mehta, Amrish ^b   Todd, Catriona ^b   Ramachandran, Radha ^a   Salem, Victoria ^a   Stamp, Gordon W ^a   Donaldson, Mandy ^b   Ghatei, Mohammad A ^a   Bloom, Stephen R ^a   Dhillo, Waljit S ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; GONADORELIN; GONADOTROPIN; LUTEINIZING HORMONE; METASTIN; SODIUM CHLORIDE;

ADULT; AMENORRHEA; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DESENSITIZATION; DOUBLE BLIND PROCEDURE; ESTRADIOL BLOOD LEVEL; FEMALE; FEMALE INFERTILITY; GONADOTROPIN BLOOD LEVEL; GONADOTROPIN RELEASE; HORMONE RELEASE; HUMAN; HYPOTHALAMUS; LUTEINIZING HORMONE BLOOD LEVEL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; REPRODUCTION; TACHYPHYLAXIS; ULTRASOUND;

EID: 70449111663     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2009-0406     Document Type: Article

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