Adiponectin increases bone mass by suppressing osteoclast and activating osteoblast

Biochemical and Biophysical Research Communications

Volumn 331, Issue 2, 2005, Pages 520-526

  Oshima, Kazuya ^a,b   Nampei, Akihide ^b   Matsuda, Morihiro ^a   Iwaki, Masanori ^a   Fukuhara, Atsunori ^a   Hashimoto, Jun ^b   Yoshikawa, Hideki ^b   Shimomura, Iichiro ^a,b,c  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Adipocytokines; Adiponectin; Adipose tissue; Bone mass; Bone metabolism; Osteoblasts; Osteoclasts; Osteopenia

Indexed keywords

ADIPONECTIN; BETA GALACTOSIDASE; CD14 ANTIGEN; COLONY STIMULATING FACTOR 1; MESSENGER RNA; OSTEOCLAST DIFFERENTIATION FACTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW; BONE MASS; BONE MINERALIZATION; CELL DIFFERENTIATION; CONTROLLED STUDY; LYMPHOCYTE TRANSFORMATION; MACROPHAGE; MALE; MONONUCLEAR CELL; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOLYSIS; OSTEOPENIA; PATIENT; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ADENOVIRIDAE;

EID: 18044394024     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.03.210     Document Type: Article

References (38)

1. D.M. Smith, M.R. Khairi, and C.C. Johnston Jr. The loss of bone mineral with aging and its relationship to risk of fracture J. Clin. Invest. 56 1975 311 318
2. B.L. Riggs, and L.J. Melton Involutional osteoporosis N. Engl. J. Med. 314 1986 1676 1686
3. M.F. Pittenger, A.M. Mackay, S.C. Beck, R.K. Jaiswal, R. Douglas, J.D. Mosca, M.A. Moorman, D.W. Simonetti, S. Craig, and D.R. Marshak Multilineage potential of adult human mesenchymal stem cells Science 284 1999 143 147
4. J.E. Dennis, A. Merriam, A. Awadallah, J.U. Yoo, B. Johnstone, and A.I. Caplan A quadripotential mesenchymal progenitor cell isolated from the marrow of an adult mouse J. Bone Miner. Res. 14 1999 700 709
5. I. Shimomura, T. Funahashi, M. Takahashi, K. Maeda, K. Kotani, T. Nakamura, S. Yamashita, M. Miura, Y. Fukuda, K. Takemura, K. Tokunaga, and Y. Matsuzawa Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity Nat. Med. 2 1996 800 803
6. G.S. Hotamisligil, N.S. Shargill, and B.M. Spiegelman Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance Science 259 1993 87 91
7. C.M. Steppan, S.T. Bailey, S. Bhat, E.J. Brown, R.R. Banerjee, C.M. Wright, H.R. Patel, R.S. Ahima, and M.A. Lazar The hormone resistin links obesity to diabetes Nature 409 2001 307 312
8. J.M. Friedman, and J.L. Halaas Leptin and the regulation of body weight in mammals Nature 395 1998 763 770
9. P. Laharrague, D. Larrouy, A.M. Fontanilles, N. Truel, A. Campfield, R. Tenenbaum, J. Galitzky, J.X. Corberand, L. Penicaud, and L. Casteilla High expression of leptin by human bone marrow adipocytes in primary culture FASEB J. 12 1998 747 752
10. T. Thomas, F. Gori, S. Khosla, M.D. Jensen, B. Burguera, and B.L. Riggs Leptin acts on human marrow stromal cells to enhance differentiation to osteoblasts and to inhibit differentiation to adipocytes Endocrinology 140 1999 1630 1638
11. B. Burguera, L.C. Hofbauer, T. Thomas, F. Gori, G.L. Evans, S. Khosla, B.L. Riggs, and R.T. Turner Leptin reduces ovariectomy-induced bone loss in rats Endocrinology 142 2001 3546 3553
12. C.M. Steppan, D.T. Crawford, K.L. Chidsey-Frink, H. Ke, and A.G. Swick Leptin is a potent stimulator of bone growth in ob/ob mice Regul. Pept. 92 2000 73 78
13. P. Ducy, M. Amling, S. Takeda, M. Priemel, A.F. Schilling, F.T. Beil, J. Shen, C. Vinson, J.M. Rueger, and G. Karsenty Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass Cell 100 2000 197 207
14. K. Maeda, K. Okubo, I. Shimomura, T. Funahashi, Y. Matsuzawa, and K. Matsubara cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (AdiPose Most abundant Gene transcript 1) Biochem. Biophys. Res. Commun. 221 1996 286 289
15. P.E. Scherer, S. Williams, M. Fogliano, G. Baldini, and H.F. Lodish A novel serum protein similar to C1q, produced exclusively in adipocytes J. Biol. Chem. 270 1995 26746 26749
16. E. Hu, P. Liang, and B.M. Spiegelman AdipoQ is a novel adipose-specific gene dysregulated in obesity J. Biol. Chem. 271 1996 10697 10703
17. T. Yamauchi, J. Kamon, H. Waki, Y. Terauchi, N. Kubota, K. Hara, Y. Mori, T. Ide, K. Murakami, N. Tsuboyama-Kasaoka, O. Ezaki, Y. Akanuma, O. Gavrilova, C. Vinson, M.L. Reitman, H. Kagechika, K. Shudo, M. Yoda, Y. Nakano, K. Tobe, R. Nagai, S. Kimura, M. Tomita, P. Froguel, and T. Kadowaki The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Nat. Med. 7 2001 941 946
18. A.H. Berg, T.P. Combs, X. Du, M. Brownlee, and P.E. Scherer The adipocyte-secreted protein Acrp30 enhances hepatic insulin action Nat. Med. 7 2001 947 953
19. N. Maeda, I. Shimomura, K. Kishida, H. Nishizawa, M. Matsuda, H. Nagaretani, N. Furuyama, H. Kondo, M. Takahashi, Y. Arita, R. Komuro, N. Ouchi, S. Kihara, Y. Tochino, K. Okutomi, M. Horie, S. Takeda, T. Aoyama, T. Funahashi, and Y. Matsuzawa Diet-induced insulin resistance in mice lacking adiponectin/ACRP30 Nat. Med. 8 2002 731 737
20. T. Yamauchi, J. Kamon, Y. Minokoshi, Y. Ito, H. Waki, S. Uchida, S. Yamashita, M. Noda, S. Kita, K. Ueki, K. Eto, Y. Akanuma, P. Froguel, F. Foufelle, P. Ferre, D. Carling, S. Kimura, R. Nagai, B.B. Kahn, and T. Kadowaki Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase Nat. Med. 8 2002 1288 1295
21. P.A. Jansson, F. Pellme, A. Hammarstedt, M. Sandqvist, H. Brekke, K. Caidahl, M. Forsberg, R. Volkmann, E. Carvalho, T. Funahashi, Y. Matsuzawa, O. Wiklund, X. Yang, M.R. Taskinen, and U. Smith A novel cellular marker of insulin resistance and early atherosclerosis in humans is related to impaired fat cell differentiation and low adiponectin FASEB J. 17 2003 1434 1440
22. Y. Kamada, S. Tamura, S. Kiso, H. Matsumoto, Y. Saji, Y. Yoshida, K. Fukui, N. Maeda, H. Nishizawa, H. Nagaretani, Y. Okamoto, S. Kihara, J. Miyagawa, Y. Shinomura, T. Funahashi, and Y. Matsuzawa Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin Gastroenterology 125 2003 1796 1807
23. E. Brakenhielm, N. Veitonmaki, R. Cao, S. Kihara, Y. Matsuzawa, B. Zhivotovsky, T. Funahashi, and Y. Cao Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis Proc. Natl. Acad. Sci. USA 101 2004 2476 2481
24. T. Yamauchi, J. Kamon, Y. Ito, A. Tsuchida, T. Yokomizo, S. Kita, T. Sugiyama, M. Miyagishi, K. Hara, M. Tsunoda, K. Murakami, T. Ohteki, S. Uchida, S. Takekawa, N. Waki, N.H. Tsuno, Y. Shibata, Y. Terauchi, P. Froguel, K. Tobe, S. Koyasu, K. Taira, T. Kitamura, T. Shimizu, R. Nagai, and T. Kadowaki Cloning of adiponectin receptors that mediate antidiabetic metabolic effects Nature 423 2003 762 769
25. H. Staiger, S. Kaltenbach, K. Staiger, N. Stefan, A. Fritsche, A. Guirguis, C. Peterfi, M. Weisser, F. Machicao, M. Stumvoll, and H.U. Haring Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism Diabetes 53 2004 2195 2201
26. G. Chinetti, C. Zawadski, J.C. Fruchart, and B. Staels Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR Biochem. Biophys. Res. Commun. 314 2004 151 158
27. M. Matsuda, I. Shimomura, M. Sata, Y. Arita, M. Nishida, N. Maeda, M. Kumada, Y. Okamoto, H. Nagaretani, H. Nishizawa, K. Kishida, R. Komuro, N. Ouchi, S. Kihara, R. Nagai, T. Funahashi, and Y. Matsuzawa Role of adiponectin in preventing vascular stenosis. The missing link of adipo-vascular axis J. Biol. Chem. 277 2002 37487 37491
28. Y. Azuma, K. Kaji, R. Katogi, S. Takeshita, and A. Kudo Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts J. Biol. Chem. 275 2000 4858 4864
29. H. Yasuda, N. Shima, N. Nakagawa, K. Yamaguchi, M. Kinosaki, S. Mochizuki, A. Tomoyasu, K. Yano, M. Goto, A. Murakami, E. Tsuda, T. Morinaga, K. Higashio, N. Udagawa, N. Takahashi, and T. Suda Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL Proc. Natl. Acad. Sci. USA 95 1998 3597 3602
30. G.C. Nicholson, M. Malakellis, F.M. Collier, P.U. Cameron, W.R. Holloway, T.J. Gough, C. Gregorio-King, M.A. Kirkland, and D.E. Myers Induction of osteoclasts from CD14-positive human peripheral blood mononuclear cells by receptor activator of nuclear factor kappaB ligand (RANKL) Clin. Sci. Lond. 99 2000 133 140
31. Y. Arita, S. Kihara, N. Ouchi, M. Takahashi, K. Maeda, J. Miyagawa, K. Hotta, I. Shimomura, T. Nakamura, K. Miyaoka, H. Kuriyama, M. Nishida, S. Yamashita, K. Okubo, K. Matsubara, M. Muraguchi, Y. Ohmoto, T. Funahashi, and Y. Matsuzawa Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity Biochem. Biophys. Res. Commun. 257 1999 79 83
32. M. Iwaki, M. Matsuda, N. Maeda, T. Funahashi, Y. Matsuzawa, M. Makishima, and I. Shimomura Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors Diabetes 52 2003 1655 1663
33. T. Maeda, A. Matsunuma, T. Kawane, and N. Horiuchi Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells Biochem. Biophys. Res. Commun. 280 2001 874 877
34. T. Tsurukai, N. Udagawa, K. Matsuzaki, N. Takahashi, and T. Suda Roles of macrophage-colony stimulating factor and osteoclast differentiation factor in osteoclastogenesis J. Bone Miner. Metab. 18 2000 177 184
35. S. Takeshita, K. Kaji, and A. Kudo Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts J. Bone Miner. Res. 15 2000 1477 1488
36. R.T. Franceschi, and B.S. Iyer Relationship between collagen synthesis and expression of the osteoblast phenotype in MC3T3-E1 cells J. Bone Miner. Res. 7 1992 235 246
37. J.A. Buckwalter, and R.R. Cooper Bone structure and function Instr. Course Lect. 36 1987 27 48
38. T. Katagiri, and N. Takahashi Regulatory mechanisms of osteoblast and osteoclast differentiation Oral Dis. 8 2002 147 159