Leucine deprivation inhibits proliferation and induces apoptosis of human breast cancer cells via fatty acid synthase

Oncotarget

Volumn 7, Issue 39, 2016, Pages 63679-63689

  Xiao, Fei ^a   Wang, Chunxia ^a   Yin, Hongkun ^a   Yu, Junjie ^a   Chen, Shanghai ^a   Fang, Jing ^a   Guo, Feifan ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Apoptosis; Breast cancer; Leucine deprivation; Proliferation

Indexed keywords

ACTIN; FATTY ACID SYNTHASE; LEUCINE; PROTEIN GCN2; PROTEIN SERINE THREONINE KINASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; UNCLASSIFIED DRUG; EIF2AK4 PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FASN PROTEIN, HUMAN; FATTY ACID; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CELL VIABILITY; CONTROLLED STUDY; DIET THERAPY; DOWN REGULATION; FASN GENE; FEMALE; FOOD DEPRIVATION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MITOSIS INHIBITION; MOUSE; MTT ASSAY; NONHUMAN; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ANIMAL; BAGG ALBINO MOUSE; BREAST TUMOR; CANCER TRANSPLANTATION; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; GENETICS; METABOLISM; NUDE MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; BREAST NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FATTY ACID SYNTHASE, TYPE I; FATTY ACIDS; FEMALE; HUMANS; LEUCINE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROTEIN-SERINE-THREONINE KINASES; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84993927166     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.11626     Document Type: Article

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