The GCN2 eIF2α Kinase Regulates Fatty-Acid Homeostasis in the Liver during Deprivation of an Essential Amino Acid

Cell Metabolism

Volumn 5, Issue 2, 2007, Pages 103-114

  Guo, Feifan ^a   Cavener, Douglas R ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

HUMDISEASE

Indexed keywords

ESSENTIAL AMINO ACID; FAS ANTIGEN; FATTY ACID; FATTY ACID SYNTHASE; INITIATION FACTOR 2ALPHA; LEUCINE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GCN2; UNCLASSIFIED DRUG; 4 METHYLENE 2 OCTYL 5 OXOFURAN 3 CARBOXYLIC ACID; 4-METHYLENE-2-OCTYL-5-OXOFURAN-3-CARBOXYLIC ACID; DRUG DERIVATIVE; EIF2AK4 PROTEIN, MOUSE; FATTY ACID BETA OXIDATION MULTIENZYME COMPLEX; FATTY ACID BETA-OXIDATION MULTIENZYME COMPLEX; FATTY ACID TRANSPORTER; GAMMA BUTYROLACTONE; INITIATION FACTOR 2; MULTIENZYME COMPLEX; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN SERINE THREONINE KINASE; REPRESSOR PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL;

ADAPTATION; ADIPOSE TISSUE; AMINO ACID DEFICIENCY; AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; FATTY LIVER; FOOD DEPRIVATION; HOMEOSTASIS; LIPID METABOLISM; LIPID STORAGE; LIPID TRANSPORT; MALNUTRITION; MAMMAL CELL; METABOLIC REGULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENSOR; WILD TYPE; YEAST CELL; ANIMAL; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; FEMALE; GENETICS; LIVER; MALE; METABOLISM; ORGAN SIZE; PATHOLOGY; PHOSPHORYLATION; UPREGULATION;

MAMMALIA; MUS;

4-BUTYROLACTONE; ADIPOSE TISSUE; ANIMALS; EUKARYOTIC INITIATION FACTOR-2; FATTY ACID SYNTHETASE COMPLEX; FATTY ACID TRANSPORT PROTEINS; FATTY ACIDS; FATTY LIVER; FEMALE; HOMEOSTASIS; LEUCINE; LIVER; MALE; MICE; MULTIENZYME COMPLEXES; ORGAN SIZE; PHOSPHORYLATION; PPAR GAMMA; PROTEIN-SERINE-THREONINE KINASES; REPRESSOR PROTEINS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES; UP-REGULATION;

EID: 33846602706     PISSN: 15504131     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cmet.2007.01.001     Document Type: Article

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