-
1
-
-
17044386953
-
Type 2 diabetes: Principles of pathogenesis and therapy
-
Stumvoll M, Goldstein BJ, van Haeften TW. Type 2 diabetes: principles of pathogenesis and therapy. Lancet 2005;365:1333-1346
-
(2005)
Lancet
, vol.365
, pp. 1333-1346
-
-
Stumvoll, M.1
Goldstein, B.J.2
Van Haeften, T.W.3
-
2
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
Kadowaki T, Yamauchi T, Kubota N, Hara K, Ueki K, Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J Clin Invest 2006;116:1784-1792
-
(2006)
J Clin Invest
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
-
4
-
-
69649084224
-
Immunomodulatory role of prolactin in diabetes development
-
Cejkova P, Fojtikova M, Cerna M. Immunomodulatory role of prolactin in diabetes development. Autoimmun Rev 2009;9:23-27
-
(2009)
Autoimmun Rev
, vol.9
, pp. 23-27
-
-
Cejkova, P.1
Fojtikova, M.2
Cerna, M.3
-
5
-
-
0032460226
-
Prolactin (PRL) and its receptor: Actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice
-
Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA. Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 1998;19:225-268
-
(1998)
Endocr Rev
, vol.19
, pp. 225-268
-
-
Bole-Feysot, C.1
Goffin, V.2
Edery, M.3
Binart, N.4
Kelly, P.A.5
-
6
-
-
0016608537
-
Prolactin receptors in rat liver: Possible induction by prolactin
-
Posner BI, Kelly PA, Friesen HG. Prolactin receptors in rat liver: possible induction by prolactin. Science 1975;188:57-59
-
(1975)
Science
, vol.188
, pp. 57-59
-
-
Posner, B.I.1
Kelly, P.A.2
Friesen, H.G.3
-
7
-
-
0024281422
-
Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family
-
Boutin JM, Jolicoeur C, Okamura H, et al. Cloning and expression of the rat prolactin receptor, a member of the growth hormone/prolactin receptor gene family. Cell 1988;53:69-77
-
(1988)
Cell
, vol.53
, pp. 69-77
-
-
Boutin, J.M.1
Jolicoeur, C.2
Okamura, H.3
-
8
-
-
84859640536
-
Prolactin signaling mechanisms in ovary
-
Bouilly J, Sonigo C, Auffret J, Gibori G, Binart N. Prolactin signaling mechanisms in ovary. Mol Cell Endocrinol 2012;356:80-87
-
(2012)
Mol Cell Endocrinol
, vol.356
, pp. 80-87
-
-
Bouilly, J.1
Sonigo, C.2
Auffret, J.3
Gibori, G.4
Binart, N.5
-
10
-
-
18344382724
-
Targeted deletion of the PRL receptor: Effects on islet development, insulin production, and glucose tolerance
-
Freemark M, Avril I, Fleenor D, et al. Targeted deletion of the PRL receptor: effects on islet development, insulin production, and glucose tolerance. Endocrinology 2002;143:1378-1385
-
(2002)
Endocrinology
, vol.143
, pp. 1378-1385
-
-
Freemark, M.1
Avril, I.2
Fleenor, D.3
-
11
-
-
63849322132
-
Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy
-
Huang C, Snider F, Cross JC. Prolactin receptor is required for normal glucose homeostasis and modulation of beta-cell mass during pregnancy. Endocrinology 2009;150:1618-1626
-
(2009)
Endocrinology
, vol.150
, pp. 1618-1626
-
-
Huang, C.1
Snider, F.2
Cross, J.C.3
-
12
-
-
11244338107
-
Participation of prolactin receptors and phosphatidylinositol 3-kinase and MAP kinase pathways in the increase in pancreatic islet mass and sensitivity to glucose during pregnancy
-
Amaral ME, Cunha DA, Anhê GF, et al. Participation of prolactin receptors and phosphatidylinositol 3-kinase and MAP kinase pathways in the increase in pancreatic islet mass and sensitivity to glucose during pregnancy. J Endocrinol 2004;183:469-476
-
(2004)
J Endocrinol
, vol.183
, pp. 469-476
-
-
Amaral, M.E.1
Cunha, D.A.2
Anhê, G.F.3
-
13
-
-
34248581989
-
Disordered lipid metabolism and the pathogenesis of insulin resistance
-
Savage DB, Petersen KF, Shulman GI. Disordered lipid metabolism and the pathogenesis of insulin resistance. Physiol Rev 2007;87:507-520
-
(2007)
Physiol Rev
, vol.87
, pp. 507-520
-
-
Savage, D.B.1
Petersen, K.F.2
Shulman, G.I.3
-
14
-
-
71549128378
-
A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling
-
García-Martínez JM, Calcabrini A, González L, et al. A non-catalytic function of the Src family tyrosine kinases controls prolactin-induced Jak2 signaling. Cell Signal 2010;22:415-426
-
(2010)
Cell Signal
, vol.22
, pp. 415-426
-
-
García-Martínez, J.M.1
Calcabrini, A.2
González, L.3
-
15
-
-
0031020425
-
Pro-lactin activates tyrosyl phosphorylation of insulin receptor substrate 1 and phosphatidylinositol-3-OH kinase
-
Berlanga JJ, Gualillo O, Buteau H, Applanat M, Kelly PA, Edery M. Pro-lactin activates tyrosyl phosphorylation of insulin receptor substrate 1 and phosphatidylinositol-3-OH kinase. J Biol Chem 1997;272:2050-2052
-
(1997)
J Biol Chem
, vol.272
, pp. 2050-2052
-
-
Berlanga, J.J.1
Gualillo, O.2
Buteau, H.3
Applanat, M.4
Kelly, P.A.5
Edery, M.6
-
16
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
Saltiel AR, Kahn CR. Insulin signalling and the regulation of glucose and lipid metabolism. Nature 2001;414:799-806
-
(2001)
Nature
, vol.414
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
17
-
-
84891812441
-
Reduced maternal nutrition in late gestation acts to decrease prolactin receptor abundance in adipose tissue and later fat deposition
-
4-6 November, London, U.K
-
Korur N, Pearce S, Dandrea J, Ingleton P, Symonds ME, Stephenson T. Reduced maternal nutrition in late gestation acts to decrease prolactin receptor abundance in adipose tissue and later fat deposition. Abstract presented at the 193rd Meeting of the Society for Endocrinology and Society for Endocrinology joint Endocrinology and Diabetes Day, 4-6 November 2002, London, U.K.
-
(2002)
193rd Meeting of the Society for Endocrinology and Society for Endocrinology Joint Endocrinology and Diabetes Day
-
-
Korur, N.1
Pearce, S.2
Dandrea, J.3
Ingleton, P.4
Symonds, M.E.5
Stephenson, T.6
-
18
-
-
0031058873
-
Dietary fat and protein intake differ in modulation of prostate tumor growth, prolactin secretion and metabolism, and prostate gland prolactin binding capacity in rats
-
Clinton SK, Mulloy AL, Li SP, Mangian HJ, Visek WJ. Dietary fat and protein intake differ in modulation of prostate tumor growth, prolactin secretion and metabolism, and prostate gland prolactin binding capacity in rats. J Nutr 1997;127:225-237
-
(1997)
J Nutr
, vol.127
, pp. 225-237
-
-
Clinton, S.K.1
Mulloy, A.L.2
Li, S.P.3
Mangian, H.J.4
Visek, W.J.5
-
19
-
-
79952374033
-
Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways
-
Xiao F, Huang Z, Li H, et al. Leucine deprivation increases hepatic insulin sensitivity via GCN2/mTOR/S6K1 and AMPK pathways. Diabetes 2011;60: 746-756
-
(2011)
Diabetes
, vol.60
, pp. 746-756
-
-
Xiao, F.1
Huang, Z.2
Li, H.3
-
20
-
-
73449107531
-
MTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms
-
Ge Y, Wu AL, Warnes C, et al. mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms. Am J Physiol Cell Physiol 2009;297:C1434-C1444
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Ge, Y.1
Wu, A.L.2
Warnes, C.3
-
21
-
-
65449159320
-
Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice
-
Wang Q, Jiang L, Wang J, et al. Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice. Hepatology 2009;49:1166-1175
-
(2009)
Hepatology
, vol.49
, pp. 1166-1175
-
-
Wang, Q.1
Jiang, L.2
Wang, J.3
-
22
-
-
34548857700
-
SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B
-
Sun C, Zhang F, Ge X, et al. SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B. Cell Metab 2007;6:307-319
-
(2007)
Cell Metab
, vol.6
, pp. 307-319
-
-
Sun, C.1
Zhang, F.2
Ge, X.3
-
23
-
-
84862653969
-
Orphan nuclear receptor estrogen-related receptor g (ERRg) is key regulator of hepatic gluconeogenesis
-
Kim DK, Ryu D, Koh M, et al. Orphan nuclear receptor estrogen-related receptor g (ERRg) is key regulator of hepatic gluconeogenesis. J Biol Chem 2012;287:21628-21639
-
(2012)
J Biol Chem
, vol.287
, pp. 21628-21639
-
-
Kim, D.K.1
Ryu, D.2
Koh, M.3
-
24
-
-
79959396328
-
Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis
-
Luo X, Zhang Y, Ruan X, et al. Fasting-induced protein phosphatase 1 regulatory subunit contributes to postprandial blood glucose homeostasis via regulation of hepatic glycogenesis. Diabetes 2011;60:1435-1445
-
(2011)
Diabetes
, vol.60
, pp. 1435-1445
-
-
Luo, X.1
Zhang, Y.2
Ruan, X.3
-
25
-
-
79960778894
-
Growth hormone-STAT5 regulation of growth, hepatocellular carcinoma, and liver metabolism
-
Baik M, Yu JH, Hennighausen L. Growth hormone-STAT5 regulation of growth, hepatocellular carcinoma, and liver metabolism. Ann N Y Acad Sci 2011;1229:29-37
-
(2011)
Ann N y Acad Sci
, vol.1229
, pp. 29-37
-
-
Baik, M.1
Yu, J.H.2
Hennighausen, L.3
-
26
-
-
0033910854
-
Age-dependent changes in phe-notypes and candidate gene analysis in a polygenic animal model of type II diabetes mellitus;
-
Ueda H, Ikegami H, Kawaguchi Y, et al. Age-dependent changes in phe-notypes and candidate gene analysis in a polygenic animal model of type II diabetes mellitus; NSY mouse. Diabetologia 2000;43:932-938
-
(2000)
NSY Mouse. Diabetologia
, vol.43
, pp. 932-938
-
-
Ueda, H.1
Ikegami, H.2
Kawaguchi, Y.3
-
27
-
-
33846602706
-
The GCN2 eIF2alpha kinase regulates fatty-acid ho-meostasis in the liver during deprivation of an essential amino acid
-
Guo F, Cavener DR. The GCN2 eIF2alpha kinase regulates fatty-acid ho-meostasis in the liver during deprivation of an essential amino acid. Cell Metab 2007;5:103-114
-
(2007)
Cell Metab
, vol.5
, pp. 103-114
-
-
Guo, F.1
Cavener, D.R.2
-
28
-
-
41049117603
-
Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter
-
Fang F, Antico G, Zheng J, Clevenger CV. Quantification of PRL/Stat5 signaling with a novel pGL4-CISH reporter. BMC Biotechnol 2008;8:11
-
(2008)
BMC Biotechnol
, vol.8
, pp. 11
-
-
Fang, F.1
Antico, G.2
Zheng, J.3
Clevenger, C.V.4
-
29
-
-
81055147508
-
Prolactin regulation of the prostate gland: A female player in a male game
-
Goffin V, Hoang DT, Bogorad RL, Nevalainen MT. Prolactin regulation of the prostate gland: a female player in a male game. Nat Rev 2011;8: 597-607
-
(2011)
Nat Rev
, vol.8
, pp. 597-607
-
-
Goffin, V.1
Hoang, D.T.2
Bogorad, R.L.3
Nevalainen, M.T.4
-
30
-
-
34548321210
-
Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration
-
Cui Y, Hosui A, Sun R, et al. Loss of signal transducer and activator of transcription 5 leads to hepatosteatosis and impaired liver regeneration. Hepatology 2007;46:504-513
-
(2007)
Hepatology
, vol.46
, pp. 504-513
-
-
Cui, Y.1
Hosui, A.2
Sun, R.3
-
31
-
-
45749150715
-
Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity
-
Lee JY, Muenzberg H, Gavrilova O, et al. Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity. PLoS One 2008;3:e1639
-
(2008)
PLoS One
, vol.3
-
-
Lee, J.Y.1
Muenzberg, H.2
Gavrilova, O.3
-
32
-
-
0028101989
-
Development of hyperglycaemia and insulin resistance in conscious genetically diabetic (C57BL/KsJ-db/db) mice
-
Kodama H, Fujita M, Yamaguchi I. Development of hyperglycaemia and insulin resistance in conscious genetically diabetic (C57BL/KsJ-db/db) mice. Diabetologia 1994;37:739-744
-
(1994)
Diabetologia
, vol.37
, pp. 739-744
-
-
Kodama, H.1
Fujita, M.2
Yamaguchi, I.3
-
33
-
-
0036300606
-
Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse
-
Hofmann SM, Dong HJ, Li Z, et al. Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse. Diabetes 2002;51:2082-2089
-
(2002)
Diabetes
, vol.51
, pp. 2082-2089
-
-
Hofmann, S.M.1
Dong, H.J.2
Li, Z.3
-
34
-
-
0028695223
-
The eIF-2 alpha kinases: Regulators of protein synthesis in starvation and stress
-
Hinnebusch AG. The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stress. Semin Cell Biol 1994;5:417-426
-
(1994)
Semin Cell Biol
, vol.5
, pp. 417-426
-
-
Hinnebusch, A.G.1
-
35
-
-
79551519965
-
Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1
-
Della Torre S, Rando G, Meda C, et al. Amino acid-dependent activation of liver estrogen receptor alpha integrates metabolic and reproductive functions via IGF-1. Cell Metab 2011;13:205-214
-
(2011)
Cell Metab
, vol.13
, pp. 205-214
-
-
Della Torre, S.1
Rando, G.2
Meda, C.3
-
36
-
-
0041856377
-
Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins
-
Olayioye MA, Guthridge MA, Stomski FC, Lopez AF, Visvader JE, Lindeman GJ. Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins. J Biol Chem 2003; 278:32929-32935
-
(2003)
J Biol Chem
, vol.278
, pp. 32929-32935
-
-
Olayioye, M.A.1
Guthridge, M.A.2
Stomski, F.C.3
Lopez, A.F.4
Visvader, J.E.5
Lindeman, G.J.6
-
37
-
-
80054114850
-
Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer
-
Furth PA, Nakles RE, Millman S, Diaz-Cruz ES, Cabrera MC. Signal transducer and activator of transcription 5 as a key signaling pathway in normal mammary gland developmental biology and breast cancer. Breast Cancer Res 2011;13:220
-
(2011)
Breast Cancer Res
, vol.13
, pp. 220
-
-
Furth, P.A.1
Nakles, R.E.2
Millman, S.3
Diaz-Cruz, E.S.4
Cabrera, M.C.5
-
38
-
-
76749146390
-
Transcriptional factors that promote formation of white adipose tissue
-
White UA, Stephens JM. Transcriptional factors that promote formation of white adipose tissue. Mol Cell Endocrinol 2010;318:10-14
-
(2010)
Mol Cell Endocrinol
, vol.318
, pp. 10-14
-
-
White, U.A.1
Stephens, J.M.2
-
39
-
-
0035912097
-
Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway
-
Santos SC, Lacronique V, Bouchaert I, et al. Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway. Oncogene 2001;20:2080-2090
-
(2001)
Oncogene
, vol.20
, pp. 2080-2090
-
-
Santos, S.C.1
Lacronique, V.2
Bouchaert, I.3
-
40
-
-
84891756401
-
Prolactin receptor
-
Oppenheim JJ, Feldman M, Durum SK, et al., Eds. New York, Academic Press
-
Goffin V, Kelly PA. Prolactin receptor. In Cytokine Reference. Oppenheim JJ, Feldman M, Durum SK, et al., Eds. New York, Academic Press, 2001, p. 1547-1562
-
(2001)
Cytokine Reference
, pp. 1547-1562
-
-
Goffin, V.1
Kelly, P.A.2
-
41
-
-
32044465506
-
TOR signaling in growth and metabolism
-
Wullschleger S, Loewith R, Hall MN. TOR signaling in growth and metabolism. Cell 2006;124:471-484
-
(2006)
Cell
, vol.124
, pp. 471-484
-
-
Wullschleger, S.1
Loewith, R.2
Hall, M.N.3
-
42
-
-
11244297916
-
Dysregulation of the TSC-mTOR pathway in human disease
-
Inoki K, Corradetti MN, Guan KL. Dysregulation of the TSC-mTOR pathway in human disease. Nat Genet 2005;37:19-24
-
(2005)
Nat Genet
, vol.37
, pp. 19-24
-
-
Inoki, K.1
Corradetti, M.N.2
Guan, K.L.3
-
43
-
-
0035094978
-
Role of leucine in the regulation of mTOR by amino acids: Revelations from structure-activity studies
-
Lynch CJ. Role of leucine in the regulation of mTOR by amino acids: revelations from structure-activity studies. J Nutr 2001;131:861S-865S
-
(2001)
J Nutr
, vol.131
-
-
Lynch, C.J.1
-
44
-
-
4544220704
-
Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity
-
Um SH, Frigerio F, Watanabe M, et al. Absence of S6K1 protects against age-and diet-induced obesity while enhancing insulin sensitivity. Nature 2004;431:200-205
-
(2004)
Nature
, vol.431
, pp. 200-205
-
-
Um, S.H.1
Frigerio, F.2
Watanabe, M.3
-
45
-
-
0032475868
-
Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1
-
Hu ZZ, Zhuang L, Meng J, Dufau ML. Transcriptional regulation of the generic promoter III of the rat prolactin receptor gene by C/EBPbeta and Sp1. J Biol Chem 1998;273:26225-26235
-
(1998)
J Biol Chem
, vol.273
, pp. 26225-26235
-
-
Hu, Z.Z.1
Zhuang, L.2
Meng, J.3
Dufau, M.L.4
-
46
-
-
41149141885
-
Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription
-
Thiaville MM, Dudenhausen EE, Zhong C, Pan YX, Kilberg MS. Deprivation of protein or amino acid induces C/EBPbeta synthesis and binding to amino acid response elements, but its action is not an absolute requirement for enhanced transcription. Biochem J 2008;410:473-484
-
(2008)
Biochem J
, vol.410
, pp. 473-484
-
-
Thiaville, M.M.1
Dudenhausen, E.E.2
Zhong, C.3
Pan, Y.X.4
Kilberg, M.S.5
-
47
-
-
37849052434
-
S2 deletion variants of human PRL receptors demonstrate that extracellular domain conformation can alter conformation of the intracellular signaling domain
-
Tan D, Huang KT, Ueda E, Walker AM. S2 deletion variants of human PRL receptors demonstrate that extracellular domain conformation can alter conformation of the intracellular signaling domain. Biochemistry 2008;47: 479-489
-
(2008)
Biochemistry
, vol.47
, pp. 479-489
-
-
Tan, D.1
Huang, K.T.2
Ueda, E.3
Walker, A.M.4
-
48
-
-
33751526473
-
Ligand-independent dimerization of the human prolactin receptor isoforms: Functional implications
-
Gadd SL, Clevenger CV. Ligand-independent dimerization of the human prolactin receptor isoforms: functional implications. Mol Endocrinol 2006; 20:2734-2746
-
(2006)
Mol Endocrinol
, vol.20
, pp. 2734-2746
-
-
Gadd, S.L.1
Clevenger, C.V.2
-
49
-
-
78650599487
-
Acetylation modulates prolactin receptor di-merization
-
Ma L, Gao JS, Guan Y, et al. Acetylation modulates prolactin receptor di-merization. Proc Natl Acad Sci USA 2010;107:19314-19319
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19314-19319
-
-
Ma, L.1
Gao, J.S.2
Guan, Y.3
-
50
-
-
0030981085
-
Effects of hyperprolactinaemia on glucose tolerance and insulin release in male and female rats
-
Reis FM, Reis AM, Coimbra CC. Effects of hyperprolactinaemia on glucose tolerance and insulin release in male and female rats. J Endocrinol 1997; 153:423-428
-
(1997)
J Endocrinol
, vol.153
, pp. 423-428
-
-
Reis, F.M.1
Reis, A.M.2
Coimbra, C.C.3
|