Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation

Molecular Cell

Volumn 63, Issue 4, 2016, Pages 593-607

  Yamaguchi, Masaya ^a   VanderLinden, Ryan ^a   Weissmann, Florian ^b   Qiao, Renping ^b   Dube, Prakash ^c   Brown, Nicholas G ^a   Haselbach, David ^c   Zhang, Wei ^d   Sidhu, Sachdev S ^d   Peters, Jan Michael ^b   Stark, Holger ^c   Schulman, Brenda A ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

^c MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; CELL CYCLE PROTEIN 20; UBIQUITIN; CDC20 PROTEIN, HUMAN; PROTEIN BINDING; UBE1 PROTEIN, HUMAN; UBE2C PROTEIN, HUMAN; UBE2S PROTEIN, HUMAN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE;

ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; M PHASE CELL CYCLE CHECKPOINT; PROTEIN BINDING; SISTER CHROMATID; UBIQUITINATION; CHROMOSOME SEGREGATION; HUMAN; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; SPINDLE APPARATUS; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ANAPHASE-PROMOTING COMPLEX-CYCLOSOME; BINDING SITES; CDC20 PROTEINS; CHROMOSOME SEGREGATION; CRYOELECTRON MICROSCOPY; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; SPINDLE APPARATUS; STRUCTURE-ACTIVITY RELATIONSHIP; UBIQUITIN; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84992740859     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.07.003     Document Type: Article

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