Ubiquitination of Cdc20 by the APC occurs through an intramolecular mechanism

Current Biology

Volumn 21, Issue 22, 2011, Pages 1870-1877

  Foe, Ian T ^a   Foster, Scott A ^a,b   Cheung, Stephanie K ^a   Deluca, Steven Z ^a   Morgan, David O ^a,b   Toczyski, David P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANAPHASE PROMOTING COMPLEX; ANAPHASE-PROMOTING COMPLEX; ARGININE; CDC20 PROTEIN, S CEREVISIAE; CELL CYCLE PROTEIN; ISOLEUCINE; SACCHAROMYCES CEREVISIAE PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANAPHASE; ARTICLE; CHEMISTRY; CYTOLOGY; GENETICS; HALF LIFE TIME; METABOLISM; POLYMERASE CHAIN REACTION; PROTEIN SUBUNIT; SACCHAROMYCES CEREVISIAE; UBIQUITINATION; WESTERN BLOTTING;

ANAPHASE; ARGININE; BLOTTING, WESTERN; CELL CYCLE PROTEINS; HALF-LIFE; ISOLEUCINE; POLYMERASE CHAIN REACTION; PROTEIN SUBUNITS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITINATION;

SACCHAROMYCETALES;

EID: 81855184983     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2011.09.051     Document Type: Article

References (44)

1. V. Sudakin, D. Ganoth, A. Dahan, H. Heller, J. Hershko, F.C. Luca, J.V. Ruderman, and A. Hershko The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosis Mol. Biol. Cell 6 1995 185 197
2. R.W. King, J.M. Peters, S. Tugendreich, M. Rolfe, P. Hieter, and M.W. Kirschner A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B Cell 81 1995 279 288
3. H.J. Yoon, A. Feoktistova, B.A. Wolfe, J.L. Jennings, A.J. Link, and K.L. Gould Proteomics analysis identifies new components of the fission and budding yeast anaphase-promoting complexes Curr. Biol. 12 2002 2048 2054 (Pubitemid 35450929)
4. B.R. Thornton, and D.P. Toczyski Precise destruction: an emerging picture of the APC Genes Dev. 20 2006 3069 3078 (Pubitemid 44790622)
5. R. Visintin, S. Prinz, and A. Amon CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis Science 278 1997 460 463 (Pubitemid 27454429)
6. M. Schwab, A.S. Lutum, and W. Seufert Yeast Hct1 is a regulator of Clb2 cyclin proteolysis Cell 90 1997 683 693 (Pubitemid 27357960)
7. I.A. Dawson, S. Roth, and S. Artavanis-Tsakonas The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae J. Cell Biol. 129 1995 725 737
8. M. Schwab, M. Neutzner, D. Möcker, and W. Seufert Yeast Hct1 recognizes the mitotic cyclin Clb2 and other substrates of the ubiquitin ligase APC EMBO J. 20 2001 5165 5175 (Pubitemid 32910911)
9. Y. Kimata, J.E. Baxter, A.M. Fry, and H. Yamano A role for the Fizzy/Cdc20 family of proteins in activation of the APC/C distinct from substrate recruitment Mol. Cell 32 2008 576 583
10. M. Shirayama, A. Tóth, M. Gálová, and K. Nasmyth APC(Cdc20) promotes exit from mitosis by destroying the anaphase inhibitor Pds1 and cyclin Clb5 Nature 402 1999 203 207
11. O. Cohen-Fix, J.M. Peters, M.W. Kirschner, and D. Koshland Anaphase initiation in Saccharomyces cerevisiae is controlled by the APC-dependent degradation of the anaphase inhibitor Pds1p Genes Dev. 10 1996 3081 3093 (Pubitemid 27020537)
12. R.A. Oliveira, and K. Nasmyth Getting through anaphase: splitting the sisters and beyond Biochem. Soc. Trans. 38 2010 1639 1644
13. H.C. Vodermaier, C. Gieffers, S. Maurer-Stroh, F. Eisenhaber, and J.M. Peters TPR subunits of the anaphase-promoting complex mediate binding to the activator protein CDH1 Curr. Biol. 13 2003 1459 1468 (Pubitemid 37078402)
14. L.A. Passmore, E.A. McCormack, S.W. Au, A. Paul, K.R. Willison, J.W. Harper, and D. Barford Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition EMBO J. 22 2003 786 796 (Pubitemid 36227781)
15. C. Kraft, H.C. Vodermaier, S. Maurer-Stroh, F. Eisenhaber, and J.M. Peters The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates Mol. Cell 18 2005 543 553 (Pubitemid 40726231)
16. M. Glotzer, A.W. Murray, and M.W. Kirschner Cyclin is degraded by the ubiquitin pathway Nature 349 1991 132 138 (Pubitemid 21912025)
17. C.M. Pfleger, and M.W. Kirschner The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1 Genes Dev. 14 2000 655 665 (Pubitemid 30176820)
18. C.W. Carroll, and D.O. Morgan The Doc1 subunit is a processivity factor for the anaphase-promoting complex Nat. Cell Biol. 4 2002 880 887 (Pubitemid 35331363)
19. C.W. Carroll, M. Enquist-Newman, and D.O. Morgan The APC subunit Doc1 promotes recognition of the substrate destruction box Curr. Biol. 15 2005 11 18 (Pubitemid 40084696)
20. P.C. da Fonseca, E.H. Kong, Z. Zhang, A. Schreiber, M.A. Williams, E.P. Morris, and D. Barford Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor Nature 470 2011 274 278
21. S. Prinz, E.S. Hwang, R. Visintin, and A. Amon The regulation of Cdc20 proteolysis reveals a role for APC components Cdc23 and Cdc27 during S phase and early mitosis Curr. Biol. 8 1998 750 760 (Pubitemid 28301161)
22. H. Yu Cdc20: a WD40 activator for a cell cycle degradation machine Mol. Cell 27 2007 3 16 (Pubitemid 46991390)
23. E. Manchado, M. Eguren, and M. Malumbres The anaphase-promoting complex/cyclosome (APC/C): cell-cycle-dependent and -independent functions Biochem. Soc. Trans. 38 2010 65 71
24. J.A. Pesin, and T.L. Orr-Weaver Regulation of APC/C activators in mitosis and meiosis Annu. Rev. Cell Dev. Biol. 24 2008 475 499
25. B.R. Thornton, T.M. Ng, M.E. Matyskiela, C.W. Carroll, D.O. Morgan, and D.P. Toczyski An architectural map of the anaphase-promoting complex Genes Dev. 20 2006 449 460 (Pubitemid 43244399)
26. J.A. Robbins, and F.R. Cross Regulated degradation of the APC coactivator Cdc20 Cell Div. 5 2010 23
27. H.H. Lim, and U. Surana Cdc20, a beta-transducin homologue, links RAD9-mediated G2/M checkpoint control to mitosis in Saccharomyces cerevisiae Mol. Gen. Genet. 253 1996 138 148 (Pubitemid 26419998)
28. J. Pan, and R.H. Chen Spindle checkpoint regulates Cdc20p stability in Saccharomyces cerevisiae Genes Dev. 18 2004 1439 1451 (Pubitemid 38780630)
29. M. Shirayama, W. Zachariae, R. Ciosk, and K. Nasmyth The Polo-like kinase Cdc5p and the WD-repeat protein Cdc20p/fizzy are regulators and substrates of the anaphase promoting complex in Saccharomyces cerevisiae EMBO J. 17 1998 1336 1349 (Pubitemid 28105513)
30. P.Y. Goh, H.H. Lim, and U. Surana Cdc20 protein contains a destruction-box but, unlike Clb2, its proteolysisis not acutely dependent on the activity of anaphase-promoting complex Eur. J. Biochem. 267 2000 434 449 (Pubitemid 30072903)
31. B.R. Thornton, and D.P. Toczyski Securin and B-cyclin/CDK are the only essential targets of the APC Nat. Cell Biol. 5 2003 1090 1094 (Pubitemid 37509116)
32. W. Zachariae, A. Shevchenko, P.D. Andrews, R. Ciosk, M. Galova, M.J. Stark, M. Mann, and K. Nasmyth Mass spectrometric analysis of the anaphase-promoting complex from yeast: identification of a subunit related to cullins Science 279 1998 1216 1219 (Pubitemid 28164375)
33. A. Amon, S. Irniger, and K. Nasmyth Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle Cell 77 1994 1037 1050 (Pubitemid 24208863)
34. M.J. Hayes, Y. Kimata, S.L. Wattam, C. Lindon, G. Mao, H. Yamano, and A.M. Fry Early mitotic degradation of Nek2A depends on Cdc20-independent interaction with the APC/C Nat. Cell Biol. 8 2006 607 614 (Pubitemid 43827354)
35. M.E. Matyskiela, and D.O. Morgan Analysis of activator-binding sites on the APC/C supports a cooperative substrate-binding mechanism Mol. Cell 34 2009 68 80
36. P.T. Spellman, G. Sherlock, M.Q. Zhang, V.R. Iyer, K. Anders, M.B. Eisen, P.O. Brown, D. Botstein, and B. Futcher Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization Mol. Biol. Cell 9 1998 3273 3297 (Pubitemid 28551928)
37. G. Zhu, P.T. Spellman, T. Volpe, P.O. Brown, D. Botstein, T.N. Davis, and B. Futcher Two yeast forkhead genes regulate the cell cycle and pseudohyphal growth Nature 406 2000 90 94 (Pubitemid 30460217)
38. M. Koranda, A. Schleiffer, L. Endler, and G. Ammerer Forkhead-like transcription factors recruit Ndd1 to the chromatin of G2/M-specific promoters Nature 406 2000 94 98 (Pubitemid 30460218)
39. A.D. Rudner, and A.W. Murray Phosphorylation by Cdc28 activates the Cdc20-dependent activity of the anaphase-promoting complex J. Cell Biol. 149 2000 1377 1390 (Pubitemid 30437613)
40. M. Rape, and M.W. Kirschner Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry Nature 432 2004 588 595 (Pubitemid 39626259)
41. J.L. Burton, V. Tsakraklides, and M.J. Solomon Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box Mol. Cell 18 2005 533 542 (Pubitemid 40726230)
42. J.A. Benanti, S.K. Cheung, M.C. Brady, and D.P. Toczyski A proteomic screen reveals SCFGrr1 targets that regulate the glycolytic-gluconeogenic switch Nat. Cell Biol. 9 2007 1184 1191 (Pubitemid 47500495)
43. J. Lopez-Mosqueda, N.L. Maas, Z.O. Jonsson, L.G. Defazio-Eli, J. Wohlschlegel, and D.P. Toczyski Damage-induced phosphorylation of Sld3 is important to block late origin firing Nature 467 2010 479 483
44. C.W. Carroll, and D.O. Morgan Enzymology of the anaphase-promoting complex Methods Enzymol. 398 2005 219 230 (Pubitemid 41578886)