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Volumn 120, Issue , 2016, Pages 63-71

Δ9-Tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors

Author keywords

Airway; Cannabinoid receptors; Epithelium; THC; Tight junctions

Indexed keywords

CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; DRONABINOL; INTERLEUKIN 1BETA; OCCLUDIN; PROTEIN ZO1; TUMOR NECROSIS FACTOR; CANNABINOID RECEPTOR AGONIST; CANNABINOID RECEPTOR ANTAGONIST; CNR2 PROTEIN, HUMAN; IL1B PROTEIN, HUMAN; LIGAND; NONSTEROID ANTIINFLAMMATORY AGENT; OCLN PROTEIN, HUMAN; PSYCHEDELIC AGENT; TIGHT JUNCTION PROTEIN; TJP1 PROTEIN, HUMAN; TNF PROTEIN, HUMAN;

EID: 84992549055     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2016.09.008     Document Type: Article
Times cited : (20)

References (28)
  • 1
    • 79959369140 scopus 로고    scopus 로고
    • The sentinel role of the airway epithelium in asthma pathogenesis
    • [1] Holgate, S.T., The sentinel role of the airway epithelium in asthma pathogenesis. Immunol. Rev. 242 (2011), 205–219.
    • (2011) Immunol. Rev. , vol.242 , pp. 205-219
    • Holgate, S.T.1
  • 2
    • 2442619064 scopus 로고    scopus 로고
    • The tight junction: a multifunctional complex
    • [2] Schneeberger, E.E., Lynch, R.D., The tight junction: a multifunctional complex. Am. J. Physiol. 286 (2004), C1213–C1228.
    • (2004) Am. J. Physiol. , vol.286 , pp. C1213-C1228
    • Schneeberger, E.E.1    Lynch, R.D.2
  • 5
    • 36549065715 scopus 로고    scopus 로고
    • Long-term asthma treatment guided by airway hyperresponsiveness in children: a randomised controlled trial
    • [5] Nuijsink, M., Hop, W.C.J., Sterk, P.J., Duiverman, E.J., De Jorgste, J.C., Grp, C.S., Long-term asthma treatment guided by airway hyperresponsiveness in children: a randomised controlled trial. Eur. Respir. J. 30 (2007), 457–466.
    • (2007) Eur. Respir. J. , vol.30 , pp. 457-466
    • Nuijsink, M.1    Hop, W.C.J.2    Sterk, P.J.3    Duiverman, E.J.4    De Jorgste, J.C.5    Grp, C.S.6
  • 7
    • 38349158960 scopus 로고    scopus 로고
    • 2 receptor pharmacology of three plant cannabinoids: Delta(9)-tetrahydrocannabinol, cannabidiol and Delta(9)-tetrahydrocannabivarin
    • 2 receptor pharmacology of three plant cannabinoids: Delta(9)-tetrahydrocannabinol, cannabidiol and Delta(9)-tetrahydrocannabivarin. Br. J. Pharmacol. 153 (2008), 199–215.
    • (2008) Br. J. Pharmacol. , vol.153 , pp. 199-215
    • Pertwee, R.G.1
  • 8
    • 84928936462 scopus 로고    scopus 로고
    • The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough
    • [8] Makwana, R., Venkatasamy, R., Spina, D., Page, C., The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough. J. Pharmacol. Exp. Ther. 353 (2015), 169–180.
    • (2015) J. Pharmacol. Exp. Ther. , vol.353 , pp. 169-180
    • Makwana, R.1    Venkatasamy, R.2    Spina, D.3    Page, C.4
  • 10
    • 33846383144 scopus 로고    scopus 로고
    • Inhaled anandamide reduces leukotriene D-4-induced airway obstruction in guinea pigs
    • [10] Stengel, P.W., Cockerham, S.L., Silbaugh, S.A., Inhaled anandamide reduces leukotriene D-4-induced airway obstruction in guinea pigs. Eur. J. Pharmacol. 557 (2007), 66–68.
    • (2007) Eur. J. Pharmacol. , vol.557 , pp. 66-68
    • Stengel, P.W.1    Cockerham, S.L.2    Silbaugh, S.A.3
  • 11
    • 84859051261 scopus 로고    scopus 로고
    • Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability
    • [11] Alhamoruni, A., Wright, K.L., Larvin, M., O'Sullivan, S.E., Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. Br. J. Pharmacol. 165 (2012), 2598–2610.
    • (2012) Br. J. Pharmacol. , vol.165 , pp. 2598-2610
    • Alhamoruni, A.1    Wright, K.L.2    Larvin, M.3    O'Sullivan, S.E.4
  • 12
    • 77957230984 scopus 로고    scopus 로고
    • Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability
    • [12] Alhamoruni, A., Lee, A.C., Wright, K.L., Larvin, M., O'Sullivan, S.E., Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. J. Pharmacol. Exp. Ther. 335 (2010), 92–102.
    • (2010) J. Pharmacol. Exp. Ther. , vol.335 , pp. 92-102
    • Alhamoruni, A.1    Lee, A.C.2    Wright, K.L.3    Larvin, M.4    O'Sullivan, S.E.5
  • 15
  • 16
    • 0029966181 scopus 로고    scopus 로고
    • Expression of interleukin-1 beta (IL-1 β) and interleukin-1 receptor antagonist (IL-1ra) on asthmatic bronchial epithelium
    • [16] Sousa, A.R., Lane, S.J., Nakhosteen, J.A., Lee, T.H., Poston, R.N., Expression of interleukin-1 beta (IL-1 β) and interleukin-1 receptor antagonist (IL-1ra) on asthmatic bronchial epithelium. Am. J. Respir. Crit. Care Med. 154 (1996), 1061–1066.
    • (1996) Am. J. Respir. Crit. Care Med. , vol.154 , pp. 1061-1066
    • Sousa, A.R.1    Lane, S.J.2    Nakhosteen, J.A.3    Lee, T.H.4    Poston, R.N.5
  • 17
    • 0037216753 scopus 로고    scopus 로고
    • Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease
    • [17] Culpitt, S.V., Rogers, D.F., Shah, P., De Matos, C., Russell, R.E.K., Donnelly, L.E., Barnes, P.J., Impaired inhibition by dexamethasone of cytokine release by alveolar macrophages from patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 167 (2003), 24–31.
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 24-31
    • Culpitt, S.V.1    Rogers, D.F.2    Shah, P.3    De Matos, C.4    Russell, R.E.K.5    Donnelly, L.E.6    Barnes, P.J.7
  • 18
    • 20544442367 scopus 로고    scopus 로고
    • Dietary salt, airway inflammation, and diffusion capacity in exercise-induced asthma
    • [18] Mickleborough, T.D., Lindlet, M.R., Ray, S., Dietary salt, airway inflammation, and diffusion capacity in exercise-induced asthma. Med. Sci. Sports Exerc. 37 (2005), 904–914.
    • (2005) Med. Sci. Sports Exerc. , vol.37 , pp. 904-914
    • Mickleborough, T.D.1    Lindlet, M.R.2    Ray, S.3
  • 19
    • 0034605705 scopus 로고    scopus 로고
    • Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery
    • [19] Foster, K.A., Avery, M.L., Yazdanian, M., Audus, K.L., Characterization of the Calu-3 cell line as a tool to screen pulmonary drug delivery. Int. J. Pharm. 208 (2000), 1–11.
    • (2000) Int. J. Pharm. , vol.208 , pp. 1-11
    • Foster, K.A.1    Avery, M.L.2    Yazdanian, M.3    Audus, K.L.4
  • 20
    • 0036125277 scopus 로고    scopus 로고
    • Permeability characteristics of Calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats
    • [20] Mathias, N.R., Timoszyk, J., Stetsko, P.I., Megill, J.R., Smith, R.L., Wall, D.A., Permeability characteristics of Calu-3 human bronchial epithelial cells: in vitro-in vivo correlation to predict lung absorption in rats. J. Drug Target. 10 (2002), 31–40.
    • (2002) J. Drug Target. , vol.10 , pp. 31-40
    • Mathias, N.R.1    Timoszyk, J.2    Stetsko, P.I.3    Megill, J.R.4    Smith, R.L.5    Wall, D.A.6
  • 21
    • 84855870732 scopus 로고    scopus 로고
    • Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison
    • [21] Vllasaliu, D., Flower, R., Garnett, M., Eaton, M., Stolnik, S., Barrier characteristics of epithelial cultures modelling the airway and intestinal mucosa: a comparison. Biochem. Biophys. Res. Commun. 415 (2001), 579–585.
    • (2001) Biochem. Biophys. Res. Commun. , vol.415 , pp. 579-585
    • Vllasaliu, D.1    Flower, R.2    Garnett, M.3    Eaton, M.4    Stolnik, S.5
  • 24
    • 0033381793 scopus 로고    scopus 로고
    • 3-(1',1'-Dimethylbutyl)-1-deoxy-Delta(8)-THC and related compounds: Synthesis of selective ligands for the CB2 receptor
    • [24] Huffman, J.W., Liddle, J., Yu, S., Aung, M.M., Abood, M.E., Wiley, J.L., Martin, B.R., 3-(1',1'-Dimethylbutyl)-1-deoxy-Delta(8)-THC and related compounds: Synthesis of selective ligands for the CB2 receptor. Bioorg. Med. Chem. 7 (1999), 2905–2914.
    • (1999) Bioorg. Med. Chem. , vol.7 , pp. 2905-2914
    • Huffman, J.W.1    Liddle, J.2    Yu, S.3    Aung, M.M.4    Abood, M.E.5    Wiley, J.L.6    Martin, B.R.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.