Rates and mechanisms of bacterial mutagenesis from maximum-depth sequencing

Nature

Volumn 534, Issue 7609, 2016, Pages 693-696

  Jee, Justin ^a,b   Rasouly, Aviram ^a   Shamovsky, Ilya ^a   Akivis, Yonatan ^a   Steinman, Susan R ^a   Mishra, Bud ^b   Nudler, Evgeny ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM; BIOASSAY; CELL; MICROBIAL ACTIVITY; MUTAGENICITY; MUTATION;

ARTICLE; BACTERIAL GROWTH; BACTERIAL MUTATION; BACTERIAL STRAIN; CELL POPULATION; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; ESCHERICHIA COLI; GENE REPLICATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HIGH THROUGHPUT SEQUENCING; IN VIVO STUDY; MICROBIAL DIVERSITY; MISMATCH REPAIR; MUTATION RATE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SURVIVAL RATE; WHOLE GENOME SEQUENCING; BACTERIAL GENOME; DNA REPLICATION; DRUG EFFECTS; GENE LOCUS; GENETIC VARIATION; GENETICS; INDEL MUTATION; METABOLISM; MOLECULAR EVOLUTION; MUTAGENESIS; PHYSIOLOGY; PROCEDURES;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; LURIA;

ANTIINFECTIVE AGENT; NUCLEOTIDE; QUINOLONE DERIVATIVE;

ANTI-BACTERIAL AGENTS; DNA DAMAGE; DNA MISMATCH REPAIR; DNA REPLICATION; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; FLUOROQUINOLONES; GENETIC LOCI; GENETIC VARIATION; GENOME, BACTERIAL; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; INDEL MUTATION; MUTAGENESIS; MUTATION RATE; NUCLEOTIDES; OXIDATIVE STRESS; TRANSCRIPTION, GENETIC;

EID: 84991784371     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature18313     Document Type: Article

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