Detection and quantification of rare mutations with massively parallel sequencing

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 23, 2011, Pages 9530-9535

  Kinde, Isaac ^a   Wu, Jian ^a   Papadopoulos, Nick ^a   Kinzler, Kenneth W ^a   Vogelstein, Bert ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Biomarkers; Cancer; Diagnostics; Early diagnosis; Genetics

Indexed keywords

DNA; DNA POLYMERASE; OLIGONUCLEOTIDE;

ARTICLE; DNA DETERMINATION; DNA SEQUENCE; DNA TEMPLATE; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MASSIVELY PARALLEL SEQUENCING; MITOCHONDRIAL GENOME; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SYNTHESIS;

BASE SEQUENCE; BETA CATENIN; DNA MUTATIONAL ANALYSIS; HUMANS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTATION; POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS;

EID: 79959353421     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1105422108     Document Type: Article

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