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Volumn 2016, Issue , 2016, Pages

Crucial Contributions by T Lymphocytes (Effector, Regulatory, and Checkpoint Inhibitor) and Cytokines (TH1, TH2, and TH17) to a Pathological Complete Response Induced by Neoadjuvant Chemotherapy in Women with Breast Cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; CAPECITABINE; CD4 ANTIGEN; CD8 ANTIGEN; CHECKPOINT KINASE INHIBITOR; CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DOCETAXEL; DOXORUBICIN; ESTROGEN RECEPTOR; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 4; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; CYTOKINE; IL17A PROTEIN, HUMAN;

EID: 84991717317     PISSN: 23148861     EISSN: 23147156     Source Type: Journal    
DOI: 10.1155/2016/4757405     Document Type: Article
Times cited : (45)

References (106)
  • 1
    • 84875938908 scopus 로고    scopus 로고
    • Cancer and the immune response
    • O. Eremin and H. Sewell, Eds., chapter 4, OUP, Oxford, UK
    • M. Aloysius, L. Walker, and O. Eremin, "Cancer and the immune response, " in Essential Immunology for Surgeons, O. Eremin and H. Sewell, Eds., chapter 4, pp. 237-302, OUP, Oxford, UK, 2011.
    • (2011) Essential Immunology for Surgeons , pp. 237-302
    • Aloysius, M.1    Walker, L.2    Eremin, O.3
  • 2
    • 84858800620 scopus 로고    scopus 로고
    • The immune contexture in human tumours: Impact on clinical outcome
    • W. H. Fridman, F. Pagès, C. Sautès-Fridman, and J. Galon, "The immune contexture in human tumours: impact on clinical outcome, " Nature Reviews Cancer, vol. 12, no. 4, pp. 298-306, 2012.
    • (2012) Nature Reviews Cancer , vol.12 , Issue.4 , pp. 298-306
    • Fridman, W.H.1    Pagès, F.2    Sautès-Fridman, C.3    Galon, J.4
  • 3
    • 84880704621 scopus 로고    scopus 로고
    • The continuum of cancer immunosurveillance: Prognostic, predictive, and mechanistic signatures
    • J. Galon, H. K. Angell, D. Bedognetti, and F. M. Marincola, "The continuum of cancer immunosurveillance: prognostic, predictive, and mechanistic signatures, " Immunity, vol. 39, no. 1, pp. 11-26, 2013.
    • (2013) Immunity , vol.39 , Issue.1 , pp. 11-26
    • Galon, J.1    Angell, H.K.2    Bedognetti, D.3    Marincola, F.M.4
  • 4
    • 84877076923 scopus 로고    scopus 로고
    • From the immune contexture to the Immunoscore: The role of prognostic and predictive immune markers in cancer
    • H. Angell and J. Galon, "From the immune contexture to the Immunoscore: The role of prognostic and predictive immune markers in cancer, " Current Opinion in Immunology, vol. 25, no. 2, pp. 261-267, 2013.
    • (2013) Current Opinion in Immunology , vol.25 , Issue.2 , pp. 261-267
    • Angell, H.1    Galon, J.2
  • 5
    • 84941797037 scopus 로고    scopus 로고
    • Classifying cancers based on T-cell infiltration and PD-L1
    • M. W. L. Teng, S. F. Ngiow, A. Ribas, and M. J. Smyth, "Classifying cancers based on T-cell infiltration and PD-L1, " Cancer Research, vol. 75, no. 11, pp. 2139-2145, 2015.
    • (2015) Cancer Research , vol.75 , Issue.11 , pp. 2139-2145
    • Teng, M.W.L.1    Ngiow, S.F.2    Ribas, A.3    Smyth, M.J.4
  • 6
    • 0037448353 scopus 로고    scopus 로고
    • Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer
    • L. Zhang, J. R. Conejo-Garcia, D. Katsaros et al., "Intratumoral T cells, recurrence, and survival in epithelial ovarian cancer, " New England Journal of Medicine, vol. 348, no. 3, pp. 203-213, 2003.
    • (2003) New England Journal of Medicine , vol.348 , Issue.3 , pp. 203-213
    • Zhang, L.1    Conejo-Garcia, J.R.2    Katsaros, D.3
  • 7
    • 29144514645 scopus 로고    scopus 로고
    • Effector memory T cells, early metastasis, and survival in colorectal cancer
    • F. Pagès, A. Berger, M. Camus et al., "Effector memory T cells, early metastasis, and survival in colorectal cancer, " The New England Journal of Medicine, vol. 353, no. 25, pp. 2654-2666, 2005.
    • (2005) The New England Journal of Medicine , vol.353 , Issue.25 , pp. 2654-2666
    • Pagès, F.1    Berger, A.2    Camus, M.3
  • 8
    • 84885701721 scopus 로고    scopus 로고
    • The tumor microenvironment: A pitch for multiple players
    • G. Schiavoni, L. Gabriele, and F. Mattei, "The tumor microenvironment: A pitch for multiple players, " Frontiers in Oncology, vol. 3, article 90, 2013.
    • (2013) Frontiers in Oncology , vol.3
    • Schiavoni, G.1    Gabriele, L.2    Mattei, F.3
  • 9
    • 73949092850 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer
    • C. Denkert, S. Loibl, A. Noske et al., "Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer, " Journal of Clinical Oncology, vol. 28, no. 1, pp. 105-113, 2010.
    • (2010) Journal of Clinical Oncology , vol.28 , Issue.1 , pp. 105-113
    • Denkert, C.1    Loibl, S.2    Noske, A.3
  • 10
    • 77958450863 scopus 로고    scopus 로고
    • Implication of tumor microenvironment in the resistance to chemotherapy in breast cancer patients
    • F. Andre, N. Berrada, and C. Desmedt, "Implication of tumor microenvironment in the resistance to chemotherapy in breast cancer patients, " Current Opinion in Oncology, vol. 22, no. 6, pp. 547-551, 2010.
    • (2010) Current Opinion in Oncology , vol.22 , Issue.6 , pp. 547-551
    • Andre, F.1    Berrada, N.2    Desmedt, C.3
  • 11
    • 84866508637 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer
    • R. Yamaguchi, M. Tanaka, A. Yano et al., "Tumor-infiltrating lymphocytes are important pathologic predictors for neoadjuvant chemotherapy in patients with breast cancer, " Human Pathology, vol. 43, no. 10, pp. 1688-1694, 2012.
    • (2012) Human Pathology , vol.43 , Issue.10 , pp. 1688-1694
    • Yamaguchi, R.1    Tanaka, M.2    Yano, A.3
  • 12
    • 33750219785 scopus 로고    scopus 로고
    • Tumor cell expression of HLA-DMassociates with a Th1 profile and predicts improved survival in breast carcinoma patients
    • S. A. Oldford, J. D. Robb, D. Codner, V. Gadag, P. H. Watson, and S. Drover, "Tumor cell expression of HLA-DMassociates with a Th1 profile and predicts improved survival in breast carcinoma patients, " International Immunology, vol. 18, no. 11, pp. 1591-1602, 2006.
    • (2006) International Immunology , vol.18 , Issue.11 , pp. 1591-1602
    • Oldford, S.A.1    Robb, J.D.2    Codner, D.3    Gadag, V.4    Watson, P.H.5    Drover, S.6
  • 13
    • 42249115188 scopus 로고    scopus 로고
    • Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating Foxp3+ regulatory T cells
    • S. Ladoire, L. Arnould, L. Apetoh et al., "Pathologic complete response to neoadjuvant chemotherapy of breast carcinoma is associated with the disappearance of tumor-infiltrating Foxp3+ regulatory T cells, " Clinical Cancer Research, vol. 14, no. 8, pp. 2413-2420, 2008.
    • (2008) Clinical Cancer Research , vol.14 , Issue.8 , pp. 2413-2420
    • Ladoire, S.1    Arnould, L.2    Apetoh, L.3
  • 14
    • 64649088372 scopus 로고    scopus 로고
    • FOXP3 expression and overall survival in breast cancer
    • A. Balsari, A. Merlo, P. Casalini et al., "FOXP3 expression and overall survival in breast cancer, " Journal of Clinical Oncology, vol. 27, no. 11, pp. 1746-1752, 2009.
    • (2009) Journal of Clinical Oncology , vol.27 , Issue.11 , pp. 1746-1752
    • Balsari, A.1    Merlo, A.2    Casalini, P.3
  • 15
    • 79956329617 scopus 로고    scopus 로고
    • Tumorinfiltrating CD8+ lymphocytes predict clinical outcome in breast cancer
    • S. M. A. Mahmoud, E. C. Paish, D. G. Powe et al., "Tumorinfiltrating CD8+ lymphocytes predict clinical outcome in breast cancer, " Journal of Clinical Oncology, vol. 29, no. 15, pp. 1949-1955, 2011.
    • (2011) Journal of Clinical Oncology , vol.29 , Issue.15 , pp. 1949-1955
    • Mahmoud, S.M.A.1    Paish, E.C.2    Powe, D.G.3
  • 16
    • 79954815112 scopus 로고    scopus 로고
    • An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer
    • S. M. A. Mahmoud, E. C. Paish, D. G. Powe et al., "An evaluation of the clinical significance of FOXP3+ infiltrating cells in human breast cancer, " Breast Cancer Research and Treatment, vol. 127, no. 1, pp. 99-108, 2011.
    • (2011) Breast Cancer Research and Treatment , vol.127 , Issue.1 , pp. 99-108
    • Mahmoud, S.M.A.1    Paish, E.C.2    Powe, D.G.3
  • 18
    • 84875962521 scopus 로고    scopus 로고
    • Therapy and host defences
    • O. Eremin and H. Sewell, Eds., chapter 7, OUP, Oxford, UK
    • M. Aloysius, C. Verma, and O. Eremin, "Therapy and host defences, " in Essential Immunology for Surgeons, O. Eremin and H. Sewell, Eds., chapter 7, pp. 379-402, OUP, Oxford, UK, 2011.
    • (2011) Essential Immunology for Surgeons , pp. 379-402
    • Aloysius, M.1    Verma, C.2    Eremin, O.3
  • 20
    • 84930649133 scopus 로고    scopus 로고
    • Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): Differential restoration of blood profiles by NAC and surgery
    • C. Verma, V. Kaewkangsadan, J. M. Eremin et al., "Natural killer (NK) cell profiles in blood and tumour in women with large and locally advanced breast cancer (LLABC) and their contribution to a pathological complete response (PCR) in the tumour following neoadjuvant chemotherapy (NAC): differential restoration of blood profiles by NAC and surgery, " Journal of Translational Medicine, vol. 13, article 180, 2015.
    • (2015) Journal of Translational Medicine , vol.13
    • Verma, C.1    Kaewkangsadan, V.2    Eremin, J.M.3
  • 21
    • 84875919484 scopus 로고    scopus 로고
    • Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: Monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in
    • women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: Failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response toNAC
    • C. Verma, J. M. Eremin, A. Robins et al., "Abnormal T regulatory cells (Tregs: FOXP3+, CTLA-4+), myeloid-derived suppressor cells (MDSCs: monocytic, granulocytic) and polarised T helper cell profiles (Th1, Th2, Th17) in women with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC) and surgery: failure of abolition of abnormal treg profile with treatment and correlation of treg levels with pathological response toNAC, " Journal of TranslationalMedicine, vol. 11, no. 1, article 16, 2013.
    • (2013) Journal of TranslationalMedicine , vol.11 , Issue.1
    • Verma, C.1    Eremin, J.M.2    Robins, A.3
  • 22
    • 84856740931 scopus 로고    scopus 로고
    • Immunological monitoring of the tumor immunoenvironment for clinical trials
    • A. M. Malyguine, S. L. Strobl, and M. R. Shurin, "Immunological monitoring of the tumor immunoenvironment for clinical trials, " Cancer Immunology, Immunotherapy, vol. 61, no. 2, pp. 239-247, 2012.
    • (2012) Cancer Immunology, Immunotherapy , vol.61 , Issue.2 , pp. 239-247
    • Malyguine, A.M.1    Strobl, S.L.2    Shurin, M.R.3
  • 23
    • 84862303759 scopus 로고    scopus 로고
    • Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes
    • G. von Minckwitz, M. Untch, J.-U. Blohmer et al., "Definition and impact of pathologic complete response on prognosis after neoadjuvant chemotherapy in various intrinsic breast cancer subtypes, " Journal of Clinical Oncology, vol. 30, no. 15, pp. 1796-1804, 2012.
    • (2012) Journal of Clinical Oncology , vol.30 , Issue.15 , pp. 1796-1804
    • Von Minckwitz, G.1    Untch, M.2    Blohmer, J.-U.3
  • 24
    • 84929192841 scopus 로고    scopus 로고
    • Women with large (? 3cm) and locally advanced breast cancers (T3, 4, N1, 2, M0) receiving neoadjuvant chemotherapy (NAC: Cyclophosphamide, doxorubicin, docetaxel): Addition of capecitabine improves 4-year diseasefree survival
    • J. Eremin, G. Cowley, L. G. Walker, E. Murray, M. Stovickova, and O. Eremin, "Women with large (? 3cm) and locally advanced breast cancers (T3, 4, N1, 2, M0) receiving neoadjuvant chemotherapy (NAC: cyclophosphamide, doxorubicin, docetaxel): Addition of capecitabine improves 4-year diseasefree survival, " SpringerPlus, vol. 4, article 9, 2015.
    • (2015) SpringerPlus , vol.4
    • Eremin, J.1    Cowley, G.2    Walker, L.G.3    Murray, E.4    Stovickova, M.5    Eremin, O.6
  • 25
    • 0142211270 scopus 로고    scopus 로고
    • A new histological grading system to assess response of breast cancers to primary chemotherapy: Prognostic significance and survival
    • K. N. Ogston, I. D. Miller, S. Payne et al., "A new histological grading system to assess response of breast cancers to primary chemotherapy: prognostic significance and survival, " Breast, vol. 12, no. 5, pp. 320-327, 2003.
    • (2003) Breast , vol.12 , Issue.5 , pp. 320-327
    • Ogston, K.N.1    Miller, I.D.2    Payne, S.3
  • 26
    • 79955964554 scopus 로고    scopus 로고
    • Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: A randomised study of sequential weekly versus three-weekly docetaxel following neoadjuvant doxorubicin and cyclophosphamide in women with primary breast cancer
    • L. G. Walker, J. M. Eremin, M. M. Aloysius et al., "Effects on quality of life, anti-cancer responses, breast conserving surgery and survival with neoadjuvant docetaxel: A randomised study of sequential weekly versus three-weekly docetaxel following neoadjuvant doxorubicin and cyclophosphamide in women with primary breast cancer, " BMC Cancer, vol. 11, article 179, 2011.
    • (2011) BMC Cancer , vol.11
    • Walker, L.G.1    Eremin, J.M.2    Aloysius, M.M.3
  • 27
    • 84867849831 scopus 로고    scopus 로고
    • Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients
    • N. Oda, K. Shimazu, Y. Naoi et al., "Intratumoral regulatory T cells as an independent predictive factor for pathological complete response to neoadjuvant paclitaxel followed by 5-FU/epirubicin/cyclophosphamide in breast cancer patients, " Breast Cancer Research and Treatment, vol. 136, no. 1, pp. 107-116, 2012.
    • (2012) Breast Cancer Research and Treatment , vol.136 , Issue.1 , pp. 107-116
    • Oda, N.1    Shimazu, K.2    Naoi, Y.3
  • 28
    • 84890428459 scopus 로고    scopus 로고
    • Predictive and prognostic factors in locally advanced breast cancer: Effect of intratumoral FOXP3+ Tregs
    • L. Demir, S. Yigit, H. Ellidokuz et al., "Predictive and prognostic factors in locally advanced breast cancer: effect of intratumoral FOXP3+ Tregs, " Clinical & ExperimentalMetastasis, vol. 30, no. 8, pp. 1047-1062, 2013.
    • (2013) Clinical & ExperimentalMetastasis , vol.30 , Issue.8 , pp. 1047-1062
    • Demir, L.1    Yigit, S.2    Ellidokuz, H.3
  • 29
    • 84896872171 scopus 로고    scopus 로고
    • Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: A retrospective multicenter study
    • M. V. Dieci, C. Criscitiello, A. Goubar et al., "Prognostic value of tumor-infiltrating lymphocytes on residual disease after primary chemotherapy for triple-negative breast cancer: A retrospective multicenter study, " Annals of Oncology, vol. 25, no. 3, pp. 611-618, 2014.
    • (2014) Annals of Oncology , vol.25 , Issue.3 , pp. 611-618
    • Dieci, M.V.1    Criscitiello, C.2    Goubar, A.3
  • 30
    • 84924076132 scopus 로고    scopus 로고
    • The evaluation of tumor-infiltrating lymphocytes (TILS) in breast cancer: Recommendations by an International TILS Working Group 2014
    • R. Salgado, C. Denkert, S. Demaria et al., "The evaluation of tumor-infiltrating lymphocytes (TILS) in breast cancer: recommendations by an International TILS Working Group 2014, " Annals of Oncology, vol. 26, no. 2, Article IDmdu450, pp. 259-271, 2015.
    • (2015) Annals of Oncology , vol.26 , Issue.2 , pp. 259-271
    • Salgado, R.1    Denkert, C.2    Demaria, S.3
  • 31
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • J. Galon, A. Costes, F. Sanchez-Cabo et al., "Type, density, and location of immune cells within human colorectal tumors predict clinical outcome, " Science, vol. 313, no. 5795, pp. 1960-1964, 2006.
    • (2006) Science , vol.313 , Issue.5795 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 32
    • 58149303099 scopus 로고    scopus 로고
    • Prognostic significance of tumor-infiltrating T-lymphocytes in primary and Metastatic lesions of advanced stage ovarian cancer
    • N. Leffers, M. J. M. Gooden, R. A. De Jong et al., "Prognostic significance of tumor-infiltrating T-lymphocytes in primary and Metastatic lesions of advanced stage ovarian cancer, " Cancer Immunology, Immunotherapy, vol. 58, no. 3, pp. 449-459, 2009.
    • (2009) Cancer Immunology, Immunotherapy , vol.58 , Issue.3 , pp. 449-459
    • Leffers, N.1    Gooden, M.J.M.2    De Jong, R.A.3
  • 33
    • 0034796870 scopus 로고    scopus 로고
    • Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy
    • S. Demaria, M. D. Volm, R. L. Shapiro et al., "Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy, " Clinical Cancer Research, vol. 7, no. 10, pp. 3025-3030, 2001.
    • (2001) Clinical Cancer Research , vol.7 , Issue.10 , pp. 3025-3030
    • Demaria, S.1    Volm, M.D.2    Shapiro, R.L.3
  • 34
    • 84865191854 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer
    • M. Ono, H. Tsuda, C. Shimizu et al., "Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer, " Breast Cancer Research and Treatment, vol. 132, no. 3, pp. 793-805, 2012.
    • (2012) Breast Cancer Research and Treatment , vol.132 , Issue.3 , pp. 793-805
    • Ono, M.1    Tsuda, H.2    Shimizu, C.3
  • 35
    • 82955217260 scopus 로고    scopus 로고
    • Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
    • N. R. West, K. Milne, P. T. Truong, N. Macpherson, B. H. Nelson, and P. H. Watson, "Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer, " Breast Cancer Research, vol. 13, no. 6, article R126, 2011.
    • (2011) Breast Cancer Research , vol.13 , Issue.6
    • West, N.R.1    Milne, K.2    Truong, P.T.3    Macpherson, N.4    Nelson, B.H.5    Watson, P.H.6
  • 36
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • S. Loi, N. Sirtaine, F. Piette et al., "Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancer trial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98, " Journal of Clinical Oncology, vol. 31, no. 7, pp. 860-867, 2013.
    • (2013) Journal of Clinical Oncology , vol.31 , Issue.7 , pp. 860-867
    • Loi, S.1    Sirtaine, N.2    Piette, F.3
  • 37
    • 84859193457 scopus 로고    scopus 로고
    • Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers
    • R. Droeser, I. Zlobec, E. Kilic et al., "Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers, " BMC Cancer, vol. 12, article 134, 2012.
    • (2012) BMC Cancer , vol.12
    • Droeser, R.1    Zlobec, I.2    Kilic, E.3
  • 38
    • 84866535934 scopus 로고    scopus 로고
    • Characterisation of tumour-infiltrating macrophages: Impact on response and survival in patients receiving primary chemotherapy for breast cancer
    • S. D. Heys, K. N. Stewart, E. J. McKenzie et al., "Characterisation of tumour-infiltrating macrophages: Impact on response and survival in patients receiving primary chemotherapy for breast cancer, " Breast Cancer Research and Treatment, vol. 135, no. 2, pp. 539-548, 2012.
    • (2012) Breast Cancer Research and Treatment , vol.135 , Issue.2 , pp. 539-548
    • Heys, S.D.1    Stewart, K.N.2    McKenzie, E.J.3
  • 39
    • 69249174148 scopus 로고    scopus 로고
    • The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer
    • R. Matkowski, I. Gisterek, A. Halon et al., "The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer, " Anticancer Research, vol. 29, no. 7, pp. 2445-2451, 2009.
    • (2009) Anticancer Research , vol.29 , Issue.7 , pp. 2445-2451
    • Matkowski, R.1    Gisterek, I.2    Halon, A.3
  • 40
    • 79958189573 scopus 로고    scopus 로고
    • In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival
    • S. Ladoire, G. Mignot, S. Dabakuyo et al., "In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival, "The Journal of Pathology, vol. 224, no. 3, pp. 389-400, 2011.
    • (2011) The Journal of Pathology , vol.224 , Issue.3 , pp. 389-400
    • Ladoire, S.1    Mignot, G.2    Dabakuyo, S.3
  • 41
    • 84899482563 scopus 로고    scopus 로고
    • Immune cell quantitation in normal breast tissue lobules with and without lobulitis
    • A. C. Degnim, R. D. Brahmbhatt, D. C. Radisky et al., "Immune cell quantitation in normal breast tissue lobules with and without lobulitis, " Breast Cancer Research and Treatment, vol. 144, no. 3, pp. 539-549, 2014.
    • (2014) Breast Cancer Research and Treatment , vol.144 , Issue.3 , pp. 539-549
    • Degnim, A.C.1    Brahmbhatt, R.D.2    Radisky, D.C.3
  • 42
    • 84876086929 scopus 로고    scopus 로고
    • Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients
    • H. J. Lee, J.-Y. Seo, J.-H. Ahn, S.-H. Ahn, and G. Gong, "Tumor-associated lymphocytes predict response to neoadjuvant chemotherapy in breast cancer patients, " Journal of Breast Cancer, vol. 16, no. 1, pp. 32-39, 2013.
    • (2013) Journal of Breast Cancer , vol.16 , Issue.1 , pp. 32-39
    • Lee, H.J.1    Seo, J.-Y.2    Ahn, J.-H.3    Ahn, S.-H.4    Gong, G.5
  • 43
    • 84887851057 scopus 로고    scopus 로고
    • Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer
    • A. N. Seo, H. J. Lee, E. J. Kim et al., "Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer, " British Journal of Cancer, vol. 109, no. 10, pp. 2705-2713, 2013.
    • (2013) British Journal of Cancer , vol.109 , Issue.10 , pp. 2705-2713
    • Seo, A.N.1    Lee, H.J.2    Kim, E.J.3
  • 44
    • 84964696930 scopus 로고    scopus 로고
    • Tumorinfiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer
    • E. García-Martínez, G. L. Gil, A. C. Benito et al., "Tumorinfiltrating immune cell profiles and their change after neoadjuvant chemotherapy predict response and prognosis of breast cancer, " Breast Cancer Research, vol. 16, no. 6, article 488, 2014.
    • (2014) Breast Cancer Research , vol.16 , Issue.6
    • García-Martínez, E.1    Gil, G.L.2    Benito, A.C.3
  • 45
    • 84991598563 scopus 로고    scopus 로고
    • Basic immunology
    • O. Eremin and H. Sewell, Eds., chapter 1, OUP, Oxford, UK
    • H. Sewell, "Basic immunology, " in Essential Immunology for Surgeons, O. Eremin and H. Sewell, Eds., chapter 1, pp. 1-160, OUP, Oxford, UK, 2011.
    • (2011) Essential Immunology for Surgeons , pp. 1-160
    • Sewell, H.1
  • 46
    • 79951804510 scopus 로고    scopus 로고
    • CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity
    • C. T. Mayer, S. Floess, A. M. Baru, K. Lahl, J. Huehn, and T. Sparwasser, "CD8+Foxp3+ T cells share developmental and phenotypic features with classical CD4+Foxp3+ regulatory T cells but lack potent suppressive activity, " European Journal of Immunology, vol. 41, no. 3, pp. 716-725, 2011.
    • (2011) European Journal of Immunology , vol.41 , Issue.3 , pp. 716-725
    • Mayer, C.T.1    Floess, S.2    Baru, A.M.3    Lahl, K.4    Huehn, J.5    Sparwasser, T.6
  • 47
    • 84866528924 scopus 로고    scopus 로고
    • Peritumoral FOXP3+ regulatory T cell is sensitive to chemotherapy while intratumoral FOXP3+ regulatory T cell is prognostic predictor of breast cancer patients
    • F. Liu, Y. Li, M. Ren et al., "Peritumoral FOXP3+ regulatory T cell is sensitive to chemotherapy while intratumoral FOXP3+ regulatory T cell is prognostic predictor of breast cancer patients, " Breast Cancer Research and Treatment, vol. 135, no. 2, pp. 459-467, 2012.
    • (2012) Breast Cancer Research and Treatment , vol.135 , Issue.2 , pp. 459-467
    • Liu, F.1    Li, Y.2    Ren, M.3
  • 48
    • 34247261531 scopus 로고    scopus 로고
    • Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
    • G. J. Bates, S. B. Fox, C. Han et al., "Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse, " Journal of Clinical Oncology, vol. 24, no. 34, pp. 5373-5380, 2006.
    • (2006) Journal of Clinical Oncology , vol.24 , Issue.34 , pp. 5373-5380
    • Bates, G.J.1    Fox, S.B.2    Han, C.3
  • 50
    • 34249074242 scopus 로고    scopus 로고
    • CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients
    • S. A. Perez, M. V. Karamouzis, D. V. Skarlos et al., "CD4+CD25+ regulatory T-cell frequency in HER-2/neu (HER)-positive and HER-negative advanced-stage breast cancer patients, " Clinical Cancer Research, vol. 13, no. 9, pp. 2714-2721, 2007.
    • (2007) Clinical Cancer Research , vol.13 , Issue.9 , pp. 2714-2721
    • Perez, S.A.1    Karamouzis, M.V.2    Skarlos, D.V.3
  • 51
    • 79251500661 scopus 로고    scopus 로고
    • Phenotypical and functional specialization of FOXP3+ regulatory T cells
    • D. J. Campbell and M. A. Koch, "Phenotypical and functional specialization of FOXP3+ regulatory T cells, " Nature Reviews Immunology, vol. 11, no. 2, pp. 119-130, 2011.
    • (2011) Nature Reviews Immunology , vol.11 , Issue.2 , pp. 119-130
    • Campbell, D.J.1    Koch, M.A.2
  • 52
    • 65549136983 scopus 로고    scopus 로고
    • Mechanisms of Foxp3+ T regulatory cellmediated suppression
    • E. M. Shevach, "Mechanisms of Foxp3+ T regulatory cellmediated suppression, " Immunity, vol. 30, no. 5, pp. 636-645, 2009.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 636-645
    • Shevach, E.M.1
  • 53
    • 77954721060 scopus 로고    scopus 로고
    • Regulatory T cells in tumor immunity
    • H. Nishikawa and S. Sakaguchi, "Regulatory T cells in tumor immunity, " International Journal of Cancer, vol. 127, no. 4, pp. 759-767, 2010.
    • (2010) International Journal of Cancer , vol.127 , Issue.4 , pp. 759-767
    • Nishikawa, H.1    Sakaguchi, S.2
  • 54
    • 0036721629 scopus 로고    scopus 로고
    • Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma
    • U. K. Liyanage, T. T. Moore, H.-G. Joo et al., "Prevalence of regulatory T cells is increased in peripheral blood and tumor microenvironment of patients with pancreas or breast adenocarcinoma, " Journal of Immunology, vol. 169, no. 5, pp. 2756-2761, 2002.
    • (2002) Journal of Immunology , vol.169 , Issue.5 , pp. 2756-2761
    • Liyanage, U.K.1    Moore, T.T.2    Joo, H.-G.3
  • 55
    • 33845590308 scopus 로고    scopus 로고
    • Tumor infiltrating FOXP3+ regulatory T-cells are associated with recurrence in pathologic stage i NSCLC patients
    • R. P. Petersen, M. J. Campa, J. Sperlazza et al., "Tumor infiltrating FOXP3+ regulatory T-cells are associated with recurrence in pathologic stage I NSCLC patients, " Cancer, vol. 107, no. 12, pp. 2866-2872, 2006.
    • (2006) Cancer , vol.107 , Issue.12 , pp. 2866-2872
    • Petersen, R.P.1    Campa, M.J.2    Sperlazza, J.3
  • 56
    • 34447277894 scopus 로고    scopus 로고
    • Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection
    • Q. Gao, S.-J. Qiu, J. Fan et al., "Intratumoral balance of regulatory and cytotoxic T cells is associated with prognosis of hepatocellular carcinoma after resection, " Journal of Clinical Oncology, vol. 25, no. 18, pp. 2586-2593, 2007.
    • (2007) Journal of Clinical Oncology , vol.25 , Issue.18 , pp. 2586-2593
    • Gao, Q.1    Qiu, S.-J.2    Fan, J.3
  • 57
    • 79959742164 scopus 로고    scopus 로고
    • Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: The paradox of colorectal cancer
    • S. Ladoire, F. Martin, and F. Ghiringhelli, "Prognostic role of FOXP3+ regulatory T cells infiltrating human carcinomas: The paradox of colorectal cancer, " Cancer Immunology, Immunotherapy, vol. 60, no. 7, pp. 909-918, 2011.
    • (2011) Cancer Immunology, Immunotherapy , vol.60 , Issue.7 , pp. 909-918
    • Ladoire, S.1    Martin, F.2    Ghiringhelli, F.3
  • 58
    • 62449250053 scopus 로고    scopus 로고
    • Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome
    • M. Gobert, I. Treilleux, N. Bendriss-Vermare et al., "Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome, " Cancer Research, vol. 69, no. 5, pp. 2000-2009, 2009.
    • (2009) Cancer Research , vol.69 , Issue.5 , pp. 2000-2009
    • Gobert, M.1    Treilleux, I.2    Bendriss-Vermare, N.3
  • 59
    • 84872608638 scopus 로고    scopus 로고
    • Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptornegative breast cancer
    • N. R. West, S. E. Kost, S. D. Martin et al., "Tumour-infiltrating FOXP3+ lymphocytes are associated with cytotoxic immune responses and good clinical outcome in oestrogen receptornegative breast cancer, " British Journal of Cancer, vol. 108, no. 1, pp. 155-162, 2013.
    • (2013) British Journal of Cancer , vol.108 , Issue.1 , pp. 155-162
    • West, N.R.1    Kost, S.E.2    Martin, S.D.3
  • 60
    • 78651098988 scopus 로고    scopus 로고
    • Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy
    • S. Ladoire, L. Arnould, G. Mignot et al., "Presence of Foxp3 expression in tumor cells predicts better survival in HER2-overexpressing breast cancer patients treated with neoadjuvant chemotherapy, " Breast Cancer Research and Treatment, vol. 125, no. 1, pp. 65-72, 2011.
    • (2011) Breast Cancer Research and Treatment , vol.125 , Issue.1 , pp. 65-72
    • Ladoire, S.1    Arnould, L.2    Mignot, G.3
  • 62
    • 35748936776 scopus 로고    scopus 로고
    • Molecular determinants of inverse agonist activity of biologicals targeting CTLA-4
    • W. A. Teft and J. Madrenas, "Molecular determinants of inverse agonist activity of biologicals targeting CTLA-4, " Journal of Immunology, vol. 179, no. 6, pp. 3631-3637, 2007.
    • (2007) Journal of Immunology , vol.179 , Issue.6 , pp. 3631-3637
    • Teft, W.A.1    Madrenas, J.2
  • 63
    • 0035806323 scopus 로고    scopus 로고
    • Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function
    • M. K. Levings, R. Sangregorio, and M.-G. Roncarolo, "Human CD25+CD4+ T regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function, "The Journal of ExperimentalMedicine, vol. 193, no. 11, pp. 1295-1302, 2001.
    • (2001) The Journal of ExperimentalMedicine , vol.193 , Issue.11 , pp. 1295-1302
    • Levings, M.K.1    Sangregorio, R.2    Roncarolo, M.-G.3
  • 64
    • 33746336533 scopus 로고    scopus 로고
    • The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory Tcell biology
    • D. M. Sansom and L. S. K. Walker, "The role of CD28 and cytotoxic T-lymphocyte antigen-4 (CTLA-4) in regulatory Tcell biology, " Immunological Reviews, vol. 212, pp. 131-148, 2006.
    • (2006) Immunological Reviews , vol.212 , pp. 131-148
    • Sansom, D.M.1    Walker, L.S.K.2
  • 66
    • 78649237729 scopus 로고    scopus 로고
    • New insights of CTLA-4 into its biological function in breast cancer
    • H. Mao, L. Zhang, Y. Yang et al., "New insights of CTLA-4 into its biological function in breast cancer, " Current Cancer Drug Targets, vol. 10, no. 7, pp. 728-736, 2010.
    • (2010) Current Cancer Drug Targets , vol.10 , Issue.7 , pp. 728-736
    • Mao, H.1    Zhang, L.2    Yang, Y.3
  • 68
    • 0028081358 scopus 로고
    • Structure and chromosomal localization of the human PD-1 gene (PDCD1)
    • T. Shinohara, M. Taniwaki, Y. Ishida, M. Kawaichi, and T. Honjo, "Structure and chromosomal localization of the human PD-1 gene (PDCD1), " Genomics, vol. 23, no. 3, pp. 704-706, 1994.
    • (1994) Genomics , vol.23 , Issue.3 , pp. 704-706
    • Shinohara, T.1    Taniwaki, M.2    Ishida, Y.3    Kawaichi, M.4    Honjo, T.5
  • 69
    • 70350572330 scopus 로고    scopus 로고
    • Doxorubicin enhances CD4+ T-cell immune responses by inducing expression of CD40 ligand and 4-1BB
    • J. Y. Park, M. J. Jang, Y. H. Chung et al., "Doxorubicin enhances CD4+ T-cell immune responses by inducing expression of CD40 ligand and 4-1BB, " International Immunopharmacology, vol. 9, no. 13-14, pp. 1530-1539, 2009.
    • (2009) International Immunopharmacology , vol.9 , Issue.13-14 , pp. 1530-1539
    • Park, J.Y.1    Jang, M.J.2    Chung, Y.H.3
  • 70
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • S. L. Topalian, C. G. Drake, and D. M. Pardoll, "Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity, " CurrentOpinion in Immunology, vol. 24, no. 2, pp. 207-212, 2012.
    • (2012) CurrentOpinion in Immunology , vol.24 , Issue.2 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 71
    • 84907486438 scopus 로고    scopus 로고
    • The programmed death-1 immune-suppressive pathway: Barrier to antitumor immunity
    • S. Ostrand-Rosenberg, L. A. Horn, and S. T. Haile, "The programmed death-1 immune-suppressive pathway: barrier to antitumor immunity, " Journal of Immunology, vol. 193, no. 8, pp. 3835-3841, 2014.
    • (2014) Journal of Immunology , vol.193 , Issue.8 , pp. 3835-3841
    • Ostrand-Rosenberg, S.1    Horn, L.A.2    Haile, S.T.3
  • 72
  • 73
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
    • H. Dong, S. E. Strome, D. R. Salomao et al., "Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion, " Nature Medicine, vol. 8, no. 8, pp. 793-800, 2002.
    • (2002) Nature Medicine , vol.8 , Issue.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.R.3
  • 74
    • 79960425148 scopus 로고    scopus 로고
    • Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis
    • Y. Cao, L. Zhang, P. Ritprajak et al., "Immunoregulatory molecule B7-H1 (CD274) contributes to skin carcinogenesis, " Cancer Research, vol. 71, no. 14, pp. 4737-4741, 2011.
    • (2011) Cancer Research , vol.71 , Issue.14 , pp. 4737-4741
    • Cao, Y.1    Zhang, L.2    Ritprajak, P.3
  • 75
    • 84864535842 scopus 로고    scopus 로고
    • Cancer: PD1 makes waves in anticancer immunotherapy
    • A. Flemming, "Cancer: PD1 makes waves in anticancer immunotherapy, " Nature Reviews Drug Discovery, vol. 11, no. 8, article 601, 2012.
    • (2012) Nature Reviews Drug Discovery , vol.11 , Issue.8
    • Flemming, A.1
  • 76
    • 84896488675 scopus 로고    scopus 로고
    • PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients
    • S. Sun, X. Fei, Y. Mao et al., "PD-1+ immune cell infiltration inversely correlates with survival of operable breast cancer patients, " Cancer Immunology, Immunotherapy, vol. 63, no. 4, pp. 395-406, 2014.
    • (2014) Cancer Immunology, Immunotherapy , vol.63 , Issue.4 , pp. 395-406
    • Sun, S.1    Fei, X.2    Mao, Y.3
  • 77
    • 0030981706 scopus 로고    scopus 로고
    • The host-tumor immune conflict: Fromimmunosuppression to resistance and destruction
    • S. Chouaib, C. Asselin-Paturel, F. Mami-Chouaib, A. Caignard, and J. Y. Blay, "The host-tumor immune conflict: fromimmunosuppression to resistance and destruction, " Immunology Today, vol. 18, no. 10, pp. 493-497, 1997.
    • (1997) Immunology Today , vol.18 , Issue.10 , pp. 493-497
    • Chouaib, S.1    Asselin-Paturel, C.2    Mami-Chouaib, F.3    Caignard, A.4    Blay, J.Y.5
  • 79
    • 0141730406 scopus 로고    scopus 로고
    • Malignant germ cell tumours of the testis express interferon-, but are resistant to endogenous interferon
    • S. Schweyer, A. Soruri, J. Peters, A. Wagner, H. J. Radzun, and A. Fayyazi, "Malignant germ cell tumours of the testis express interferon-, but are resistant to endogenous interferon-, " British Journal of Cancer, vol. 89, no. 5, pp. 915-921, 2003.
    • (2003) British Journal of Cancer , vol.89 , Issue.5 , pp. 915-921
    • Schweyer, S.1    Soruri, A.2    Peters, J.3    Wagner, A.4    Radzun, H.J.5    Fayyazi, A.6
  • 80
    • 33746721569 scopus 로고    scopus 로고
    • Relationship between IL-10 and tumormarkers in breast cancer patients
    • L. Llanes-Fernández, R. I. Álvarez-Goyanes, M. D. C. Arango-Prado et al., "Relationship between IL-10 and tumormarkers in breast cancer patients, " Breast, vol. 15, no. 4, pp. 482-489, 2006.
    • (2006) Breast , vol.15 , Issue.4 , pp. 482-489
    • Llanes-Fernández, L.1    Álvarez-Goyanes, R.I.2    Arango-Prado, M.D.C.3
  • 81
    • 84855587806 scopus 로고    scopus 로고
    • Expression of Th17 cells in breast cancer tissue and its association with clinical parameters
    • L. Yang, Y. Qi, J. Hu, L. Tang, S. Zhao, and B. Shan, "Expression of Th17 cells in breast cancer tissue and its association with clinical parameters, " Cell Biochemistry and Biophysics, vol. 62, no. 1, pp. 153-159, 2012.
    • (2012) Cell Biochemistry and Biophysics , vol.62 , Issue.1 , pp. 153-159
    • Yang, L.1    Qi, Y.2    Hu, J.3    Tang, L.4    Zhao, S.5    Shan, B.6
  • 82
    • 84878551352 scopus 로고    scopus 로고
    • Interleukin-1β promotes skeletal colonization and progression of metastatic prostate cancer cells with neuroendocrine features
    • Q. Liu, M. R. Russell, K. Shahriari et al., "Interleukin-1β promotes skeletal colonization and progression of metastatic prostate cancer cells with neuroendocrine features, " Cancer Research, vol. 73, no. 11, pp. 3297-3305, 2013.
    • (2013) Cancer Research , vol.73 , Issue.11 , pp. 3297-3305
    • Liu, Q.1    Russell, M.R.2    Shahriari, K.3
  • 83
    • 84899861265 scopus 로고    scopus 로고
    • Different molecular profiles are associated with breast cancer cell homing compared with colonisation of bone: Evidence using a novel bone-seeking cell line
    • F. Nutter, I. Holen, H. K. Brown et al., "Different molecular profiles are associated with breast cancer cell homing compared with colonisation of bone: evidence using a novel bone-seeking cell line, " Endocrine-Related Cancer, vol. 21, no. 2, pp. 327-341, 2014.
    • (2014) Endocrine-Related Cancer , vol.21 , Issue.2 , pp. 327-341
    • Nutter, F.1    Holen, I.2    Brown, H.K.3
  • 85
    • 27744450587 scopus 로고    scopus 로고
    • Effects of interleukin 4 on CD25+CD4+ regulatory T cell function
    • P. Maerten, C. Shen, D. M. A. Bullens et al., "Effects of interleukin 4 on CD25+CD4+ regulatory T cell function, " Journal of Autoimmunity, vol. 25, no. 2, pp. 112-120, 2005.
    • (2005) Journal of Autoimmunity , vol.25 , Issue.2 , pp. 112-120
    • Maerten, P.1    Shen, C.2    Bullens, D.M.A.3
  • 86
    • 68949103932 scopus 로고    scopus 로고
    • STAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells
    • B. B. L. Pillemer, Z. Qi, B. Melgert, T. B. Oriss, P. Ray, and A. Ray, "STAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells, " Journal of Immunology, vol. 183, no. 1, pp. 155-163, 2009.
    • (2009) Journal of Immunology , vol.183 , Issue.1 , pp. 155-163
    • Pillemer, B.B.L.1    Qi, Z.2    Melgert, B.3    Oriss, T.B.4    Ray, P.5    Ray, A.6
  • 88
    • 0037849915 scopus 로고    scopus 로고
    • Interleukin-17 promotes angiogenesis and tumor growth
    • M. Numasaki, J.-I. Fukushi, M. Ono et al., "Interleukin-17 promotes angiogenesis and tumor growth, " Blood, vol. 101, no. 7, pp. 2620-2627, 2003.
    • (2003) Blood , vol.101 , Issue.7 , pp. 2620-2627
    • Numasaki, M.1    Fukushi, J.-I.2    Ono, M.3
  • 89
    • 58849124250 scopus 로고    scopus 로고
    • CCR6 regulates the migration of inflammatory and regulatory T cells
    • T. Yamazaki, X. O. Yang, Y. Chung et al., "CCR6 regulates the migration of inflammatory and regulatory T cells, " Journal of Immunology, vol. 181, no. 12, pp. 8391-8401, 2008.
    • (2008) Journal of Immunology , vol.181 , Issue.12 , pp. 8391-8401
    • Yamazaki, T.1    Yang, X.O.2    Chung, Y.3
  • 90
    • 0037085768 scopus 로고    scopus 로고
    • Interleukin-17 inhibits tumor cell growth bymeans of a T-cell-dependent mechanism
    • F. Benchetrit, A. Ciree, V. Vives et al., "Interleukin-17 inhibits tumor cell growth bymeans of a T-cell-dependent mechanism, " Blood, vol. 99, no. 6, pp. 2114-2121, 2002.
    • (2002) Blood , vol.99 , Issue.6 , pp. 2114-2121
    • Benchetrit, F.1    Ciree, A.2    Vives, V.3
  • 91
    • 79955758706 scopus 로고    scopus 로고
    • Th17 cells in cancer: Help or hindrance
    • C. M. Wilke, I. Kryczek, S. Wei et al., "Th17 cells in cancer: help or hindrance" Carcinogenesis, vol. 32, no. 5, pp. 643-649, 2011.
    • (2011) Carcinogenesis , vol.32 , Issue.5 , pp. 643-649
    • Wilke, C.M.1    Kryczek, I.2    Wei, S.3
  • 92
    • 77549083441 scopus 로고    scopus 로고
    • Transforming growth factor beta (TGF-β) and inflammation in cancer
    • B. Bierie and H. L. Moses, "Transforming growth factor beta (TGF-β) and inflammation in cancer, " Cytokine & Growth Factor Reviews, vol. 21, no. 1, pp. 49-59, 2010.
    • (2010) Cytokine & Growth Factor Reviews , vol.21 , Issue.1 , pp. 49-59
    • Bierie, B.1    Moses, H.L.2
  • 93
    • 58149214356 scopus 로고    scopus 로고
    • Global mapping of H3K4me3 and H3k27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells
    • G. Wei, L. Wei, J. Zhu et al., "Global mapping of H3K4me3 and H3k27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T cells, " Immunity, vol. 30, no. 1, pp. 155-167, 2009.
    • (2009) Immunity , vol.30 , Issue.1 , pp. 155-167
    • Wei, G.1    Wei, L.2    Zhu, J.3
  • 94
    • 34249799285 scopus 로고    scopus 로고
    • Cutting edge: Regulatory T cells induce CD4+CD25?Foxp3? T cells or are selfinduced to becomeTh17 cells in the absence of exogenous TGF-β
    • L. Xu, A. Kitani, I. Fuss, and W. Strober, "Cutting edge: regulatory T cells induce CD4+CD25?Foxp3? T cells or are selfinduced to becomeTh17 cells in the absence of exogenous TGF-β, " The Journal of Immunology, vol. 178, no. 11, pp. 6725-6729, 2007.
    • (2007) The Journal of Immunology , vol.178 , Issue.11 , pp. 6725-6729
    • Xu, L.1    Kitani, A.2    Fuss, I.3    Strober, W.4
  • 95
    • 0036649794 scopus 로고    scopus 로고
    • Immune changes in patients with advanced breast cancer undergoing chemotherapy with taxanes
    • N. Tsavaris, C. Kosmas, M. Vadiaka, P. Kanelopoulos, and D. Boulamatsis, "Immune changes in patients with advanced breast cancer undergoing chemotherapy with taxanes, " British Journal of Cancer, vol. 87, no. 1, pp. 21-27, 2002.
    • (2002) British Journal of Cancer , vol.87 , Issue.1 , pp. 21-27
    • Tsavaris, N.1    Kosmas, C.2    Vadiaka, M.3    Kanelopoulos, P.4    Boulamatsis, D.5
  • 96
    • 77950866195 scopus 로고    scopus 로고
    • Consecutive low doses of cyclophosphamide preferentially target Tregs and potentiate T cell responses induced by DNA PLG microparticle immunization
    • C. M. Barbon, M. Yang, G. D. Wands et al., "Consecutive low doses of cyclophosphamide preferentially target Tregs and potentiate T cell responses induced by DNA PLG microparticle immunization, " Cellular Immunology, vol. 262, no. 2, pp. 150-161, 2010.
    • (2010) Cellular Immunology , vol.262 , Issue.2 , pp. 150-161
    • Barbon, C.M.1    Yang, M.2    Wands, G.D.3
  • 97
    • 84863924314 scopus 로고    scopus 로고
    • Regulatory T-cellmodulation using cyclophosphamide in vaccine approaches: A current perspective
    • D. T. Le and E. M. Jaffee, "Regulatory T-cellmodulation using cyclophosphamide in vaccine approaches: A current perspective, " Cancer Research, vol. 72, no. 14, pp. 3439-3444, 2012.
    • (2012) Cancer Research , vol.72 , Issue.14 , pp. 3439-3444
    • Le, D.T.1    Jaffee, E.M.2
  • 98
    • 29144530630 scopus 로고    scopus 로고
    • Caspasedependent immunogenicity of doxorubicin-induced tumor cell death
    • N. Casares, M. O. Pequignot, A. Tesniere et al., "Caspasedependent immunogenicity of doxorubicin-induced tumor cell death, " The Journal of Experimental Medicine, vol. 202, no. 12, pp. 1691-1701, 2005.
    • (2005) The Journal of Experimental Medicine , vol.202 , Issue.12 , pp. 1691-1701
    • Casares, N.1    Pequignot, M.O.2    Tesniere, A.3
  • 99
    • 84857997683 scopus 로고    scopus 로고
    • A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death
    • A. D. Garg, D. V. Krysko, T. Verfaillie et al., "A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death, " The EMBO Journal, vol. 31, no. 5, pp. 1062-1079, 2012.
    • (2012) The EMBO Journal , vol.31 , Issue.5 , pp. 1062-1079
    • Garg, A.D.1    Krysko, D.V.2    Verfaillie, T.3
  • 100
    • 84864128654 scopus 로고    scopus 로고
    • Cardiac glycosides exert anticancer effects by inducing immunogenic cell death
    • L. Menger, E. Vacchelli, S. Adjemian et al., "Cardiac glycosides exert anticancer effects by inducing immunogenic cell death, " Science Translational Medicine, vol. 4, no. 143, Article ID 143ra99, 2012.
    • (2012) Science Translational Medicine , vol.4 , Issue.143
    • Menger, L.1    Vacchelli, E.2    Adjemian, S.3
  • 101
    • 79960426821 scopus 로고    scopus 로고
    • Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors
    • S. R. Mattarollo, S. Loi, H. Duret, Y. Ma, L. Zitvogel, and M. J. Smyth, "Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors, " Cancer Research, vol. 71, no. 14, pp. 4809-4820, 2011.
    • (2011) Cancer Research , vol.71 , Issue.14 , pp. 4809-4820
    • Mattarollo, S.R.1    Loi, S.2    Duret, H.3    Ma, Y.4    Zitvogel, L.5    Smyth, M.J.6
  • 102
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • F. Ghiringhelli, C. Menard, P. E. Puig et al., "Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients, " Cancer Immunology, Immunotherapy, vol. 56, no. 5, pp. 641-648, 2007.
    • (2007) Cancer Immunology, Immunotherapy , vol.56 , Issue.5 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.E.3
  • 103
    • 0034443676 scopus 로고    scopus 로고
    • Cellular immune profile of patients with advanced cancer before and after taxane treatment
    • A. W. Tong, B. Seamour, J. M. Lawson et al., "Cellular immune profile of patients with advanced cancer before and after taxane treatment, " American Journal of Clinical Oncology: Cancer Clinical Trials, vol. 23, no. 5, pp. 463-472, 2000.
    • (2000) American Journal of Clinical Oncology: Cancer Clinical Trials , vol.23 , Issue.5 , pp. 463-472
    • Tong, A.W.1    Seamour, B.2    Lawson, J.M.3
  • 104
    • 80053280757 scopus 로고    scopus 로고
    • Immune modulation by chemotherapy or immunotherapy to enhance cancer vaccines
    • G. M. Weir, R. S. Liwski, and M. Mansour, "Immune modulation by chemotherapy or immunotherapy to enhance cancer vaccines, " Cancers, vol. 3, no. 3, pp. 3114-3142, 2011.
    • (2011) Cancers , vol.3 , Issue.3 , pp. 3114-3142
    • Weir, G.M.1    Liwski, R.S.2    Mansour, M.3
  • 105
    • 77951086882 scopus 로고    scopus 로고
    • 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • J. Vincent, G. Mignot, F. Chalmin et al., "5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity, " Cancer Research, vol. 70, no. 8, pp. 3052-3061, 2010.
    • (2010) Cancer Research , vol.70 , Issue.8 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3
  • 106
    • 84937837169 scopus 로고    scopus 로고
    • Molecular and cellular insights into T cell exhaustion
    • E. J. Wherry and M. Kurachi, "Molecular and cellular insights into T cell exhaustion, " Nature Reviews Immunology, vol. 15, no. 8, pp. 486-499, 2015.
    • (2015) Nature Reviews Immunology , vol.15 , Issue.8 , pp. 486-499
    • Wherry, E.J.1    Kurachi, M.2


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