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Volumn 3, Issue 3, 2011, Pages 3114-3142

Immune modulation by chemotherapy or immunotherapy to enhance cancer vaccines

Author keywords

Cancer; Chemotherapy; Immune modulation; Immunotherapy; Vaccine

Indexed keywords

ANTHRACYCLINE; ANTINEOPLASTIC AGENT; CANCER VACCINE; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; DACARBAZINE; DOXORUBICIN; EPIRUBICIN; FLUOROURACIL; GEMCITABINE; GLUCOCORTICOID INDUCED TUMOR NECROSIS FACTOR RECEPTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR VACCINE; INTERLEUKIN 2; IPILIMUMAB; MDX 1106; MITOMYCIN C; MONOCLONAL ANTIBODY; MUCIN 1; NAVELBINE; OXALIPLATIN; PACLITAXEL; PEPTIDE VACCINE; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN ANTIBODY; TEMOZOLOMIDE; TICILIMUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 80053280757     PISSN: None     EISSN: 20726694     Source Type: Journal    
DOI: 10.3390/cancers3033114     Document Type: Review
Times cited : (70)

References (144)
  • 1
    • 33749073242 scopus 로고    scopus 로고
    • An anniversary for cancer chemotherapy
    • Hirsch, J. An anniversary for cancer chemotherapy. JAMA 2006, 296, 1518-1520.
    • (2006) JAMA , vol.296 , pp. 1518-1520
    • Hirsch, J.1
  • 3
    • 81255137064 scopus 로고    scopus 로고
    • Evolution of platinum resistance in high-grade serous ovarian cancer
    • doi:10.1016/S1470-2045(11)70123-1
    • Cooke, S.L.; Brenton, J.D. Evolution of platinum resistance in high-grade serous ovarian cancer. Lancet. Oncol. 2011 doi:10.1016/S1470-2045(11)70123-1.
    • (2011) Lancet. Oncol
    • Cooke, S.L.1    Brenton, J.D.2
  • 4
    • 79955632963 scopus 로고    scopus 로고
    • Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens: DNA damage accumulation contribution
    • Boeckmann, L.; Nickel, A.C.; Kuschal, C.; Schaefer, A.; Thoms, K.M.; Schon, M.P.; Thomale, J.; Emmert, S. Temozolomide chemoresistance heterogeneity in melanoma with different treatment regimens: DNA damage accumulation contribution. Melanoma Res. 2011, 21, 206-216.
    • (2011) Melanoma Res , vol.21 , pp. 206-216
    • Boeckmann, L.1    Nickel, A.C.2    Kuschal, C.3    Schaefer, A.4    Thoms, K.M.5    Schon, M.P.6    Thomale, J.7    Emmert, S.8
  • 6
    • 72849134093 scopus 로고    scopus 로고
    • Risk of additional cancers in untreated and treated hairy cell leukemia patients
    • Dasanu, C.A.; Alexandrescu, D.T. Risk of additional cancers in untreated and treated hairy cell leukemia patients. Expert. Opin. Pharmacother. 2010, 11, 41-50.
    • (2010) Expert. Opin. Pharmacother , vol.11 , pp. 41-50
    • Dasanu, C.A.1    Alexandrescu, D.T.2
  • 7
    • 79952281795 scopus 로고    scopus 로고
    • Improving cancer immunotherapy by targeting tumor-induced immune suppression
    • Stewart, T.J.; Smyth, M.J. Improving cancer immunotherapy by targeting tumor-induced immune suppression. Cancer Metastasis. Rev. 2011, 30, 125-140.
    • (2011) Cancer Metastasis. Rev , vol.30 , pp. 125-140
    • Stewart, T.J.1    Smyth, M.J.2
  • 9
    • 77955549860 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells: More mechanisms for inhibiting antitumor immunity
    • Ostrand-Rosenberg, S. Myeloid-derived suppressor cells: more mechanisms for inhibiting antitumor immunity. Cancer Immunol. Immunother. 2010, 59, 1593-1600.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 1593-1600
    • Ostrand-Rosenberg, S.1
  • 13
    • 78049243425 scopus 로고    scopus 로고
    • Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth
    • Teng, M.W.; Ngiow, S.F.; von Scheidt, B.; McLaughlin, N.; Sparwasser, T.; Smyth, M.J. Conditional regulatory T-cell depletion releases adaptive immunity preventing carcinogenesis and suppressing established tumor growth. Cancer Res. 2010, 70, 7800-7809.
    • (2010) Cancer Res , vol.70 , pp. 7800-7809
    • Teng, M.W.1    Ngiow, S.F.2    von Scheidt, B.3    McLaughlin, N.4    Sparwasser, T.5    Smyth, M.J.6
  • 14
    • 77954704449 scopus 로고    scopus 로고
    • Prognostic significance of regulatory T cells in tumor
    • Wilke, C.M.; Wu, K.; Zhao, E.; Wang, G.; Zou, W. Prognostic significance of regulatory T cells in tumor. Int. J. Cancer 2010, 127, 748-758.
    • (2010) Int. J. Cancer , vol.127 , pp. 748-758
    • Wilke, C.M.1    Wu, K.2    Zhao, E.3    Wang, G.4    Zou, W.5
  • 15
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou, W. Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol. 2006, 6, 295-307.
    • (2006) Nat. Rev. Immunol , vol.6 , pp. 295-307
    • Zou, W.1
  • 16
    • 79958068139 scopus 로고    scopus 로고
    • Myeloid cell population dynamics in healthy and tumorbearing mice
    • Ueha, S.; Shand, F.H.; Matsushima, K. Myeloid cell population dynamics in healthy and tumorbearing mice. Int. Immunopharmacol. 2011, 11, 783-788.
    • (2011) Int. Immunopharmacol , vol.11 , pp. 783-788
    • Ueha, S.1    Shand, F.H.2    Matsushima, K.3
  • 18
    • 29644442445 scopus 로고    scopus 로고
    • Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression
    • Bunt, S.K.; Sinha, P.; Clements, V.K.; Leips, J.; Ostrand-Rosenberg, S. Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression. J. Immunol. 2006, 176, 284-290.
    • (2006) J. Immunol , vol.176 , pp. 284-290
    • Bunt, S.K.1    Sinha, P.2    Clements, V.K.3    Leips, J.4    Ostrand-Rosenberg, S.5
  • 23
    • 54349109050 scopus 로고    scopus 로고
    • Murine ovarian cancer vascular leukocytes require arginase-1 activity for T cell suppression
    • Bak, S.P.; Alonso, A.; Turk, M.J.; Berwin, B. Murine ovarian cancer vascular leukocytes require arginase-1 activity for T cell suppression. Mol. Immunol. 2008, 46, 258-268.
    • (2008) Mol. Immunol , vol.46 , pp. 258-268
    • Bak, S.P.1    Alonso, A.2    Turk, M.J.3    Berwin, B.4
  • 24
    • 75149123468 scopus 로고    scopus 로고
    • Myeloidderived suppressor cells inhibit T-cell activation by depleting cystine and cysteine
    • Srivastava, M.K.; Sinha, P.; Clements, V.K.; Rodriguez, P.; Ostrand-Rosenberg, S. Myeloidderived suppressor cells inhibit T-cell activation by depleting cystine and cysteine. Cancer Res. 2010, 70, 68-77.
    • (2010) Cancer Res , vol.70 , pp. 68-77
    • Srivastava, M.K.1    Sinha, P.2    Clements, V.K.3    Rodriguez, P.4    Ostrand-Rosenberg, S.5
  • 26
    • 77950829023 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induced by myeloid-derived suppressor cells
    • Nagaraj, S.; Schrum, A.G.; Cho, H.I.; Celis, E.; Gabrilovich, D.I. Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J. Immunol. 2010, 184, 3106-3116.
    • (2010) J. Immunol , vol.184 , pp. 3106-3116
    • Nagaraj, S.1    Schrum, A.G.2    Cho, H.I.3    Celis, E.4    Gabrilovich, D.I.5
  • 28
    • 48549085973 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells
    • Serafini, P.; Mgebroff, S.; Noonan, K.; Borrello, I. Myeloid-derived suppressor cells promote cross-tolerance in B-cell lymphoma by expanding regulatory T cells. Cancer Res. 2008, 68, 5439-5449.
    • (2008) Cancer Res , vol.68 , pp. 5439-5449
    • Serafini, P.1    Mgebroff, S.2    Noonan, K.3    Borrello, I.4
  • 29
    • 75149179545 scopus 로고    scopus 로고
    • Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer
    • Pan, P.Y.; Ma, G.; Weber, K.J.; Ozao-Choy, J.; Wang, G.; Yin, B.; Divino, C.M.; Chen, S.H. Immune stimulatory receptor CD40 is required for T-cell suppression and T regulatory cell activation mediated by myeloid-derived suppressor cells in cancer. Cancer Res. 2010, 70, 99-108.
    • (2010) Cancer Res , vol.70 , pp. 99-108
    • Pan, P.Y.1    Ma, G.2    Weber, K.J.3    Ozao-Choy, J.4    Wang, G.5    Yin, B.6    Divino, C.M.7    Chen, S.H.8
  • 32
    • 71849109766 scopus 로고    scopus 로고
    • Tumors induce the formation of suppressor endothelial cells in vivo
    • Mulligan, J.K.; Young, M.R. Tumors induce the formation of suppressor endothelial cells in vivo. Cancer Immunol. Immunother. 2010, 59, 267-277.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 267-277
    • Mulligan, J.K.1    Young, M.R.2
  • 33
    • 77954351127 scopus 로고    scopus 로고
    • Regulatory natural killer cells in murine liver and their immunosuppressive capacity
    • Yoshida, O.; Akbar, S.M.; Chen, S.; Miyake, T.; Abe, M.; Murakami, H.; Hiasa, Y.; Onji, M. Regulatory natural killer cells in murine liver and their immunosuppressive capacity. Liver Int. 2010, 30, 906-912.
    • (2010) Liver Int , vol.30 , pp. 906-912
    • Yoshida, O.1    Akbar, S.M.2    Chen, S.3    Miyake, T.4    Abe, M.5    Murakami, H.6    Hiasa, Y.7    Onji, M.8
  • 34
    • 0035461061 scopus 로고    scopus 로고
    • + cells demonstrating a suppressor T cell-like function in the peripheral blood of colon cancer patients
    • + cells demonstrating a suppressor T cell-like function in the peripheral blood of colon cancer patients. Int. J. Oncol. 2001, 19, 561-566.
    • (2001) Int. J. Oncol , vol.19 , pp. 561-566
    • Akagi, J.1    Takai, E.2    Tamori, Y.3    Ogawa, M.4
  • 35
    • 0032520053 scopus 로고    scopus 로고
    • HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions
    • Vitale, M.; Rezzani, R.; Rodella, L.; Zauli, G.; Grigolato, P.; Cadei, M.; Hicklin, D.J.; Ferrone, S. HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions. Cancer Res. 1998, 58, 737-742.
    • (1998) Cancer Res , vol.58 , pp. 737-742
    • Vitale, M.1    Rezzani, R.2    Rodella, L.3    Zauli, G.4    Grigolato, P.5    Cadei, M.6    Hicklin, D.J.7    Ferrone, S.8
  • 37
    • 0038666364 scopus 로고    scopus 로고
    • Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation
    • Seliger, B.; Atkins, D.; Bock, M.; Ritz, U.; Ferrone, S.; Huber, C.; Storkel, S. Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation. Clin. Cancer Res. 2003, 9, 1721-1727.
    • (2003) Clin. Cancer Res , vol.9 , pp. 1721-1727
    • Seliger, B.1    Atkins, D.2    Bock, M.3    Ritz, U.4    Ferrone, S.5    Huber, C.6    Storkel, S.7
  • 38
  • 40
    • 70350500225 scopus 로고    scopus 로고
    • STATs in cancer inflammation and immunity: A leading role for STAT3
    • Yu, H.; Pardoll, D.; Jove, R. STATs in cancer inflammation and immunity: A leading role for STAT3. Nat. Rev. Cancer 2009, 9, 798-809.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 798-809
    • Yu, H.1    Pardoll, D.2    Jove, R.3
  • 41
    • 73449126570 scopus 로고    scopus 로고
    • Mechanisms of chemotherapeutic drug resistance in cancer therapy-A quick review
    • Liu, F.S. Mechanisms of chemotherapeutic drug resistance in cancer therapy-A quick review. Taiwan J. Obstet. Gynecol. 2009, 48, 239-244.
    • (2009) Taiwan J. Obstet. Gynecol , vol.48 , pp. 239-244
    • Liu, F.S.1
  • 43
    • 78249290274 scopus 로고    scopus 로고
    • Personalized cancer vaccines
    • Jain, K.K. Personalized cancer vaccines. Expert Opin. Biol. Ther. 2010, 10, 1637-1647.
    • (2010) Expert Opin. Biol. Ther , vol.10 , pp. 1637-1647
    • Jain, K.K.1
  • 47
    • 61449258305 scopus 로고    scopus 로고
    • Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C)
    • Salem, M.L.; Diaz-Montero, C.M.; Al-Khami, A.A.; El-Naggar, S.A.; Naga, O.; Montero, A.J.; Khafagy, A.; Cole, D.J. Recovery from cyclophosphamide-induced lymphopenia results in expansion of immature dendritic cells which can mediate enhanced prime-boost vaccination antitumor responses in vivo when stimulated with the TLR3 agonist poly(I:C). J. Immunol. 2009, 182, 2030-2040.
    • (2009) J. Immunol , vol.182 , pp. 2030-2040
    • Salem, M.L.1    Diaz-Montero, C.M.2    Al-Khami, A.A.3    El-Naggar, S.A.4    Naga, O.5    Montero, A.J.6    Khafagy, A.7    Cole, D.J.8
  • 48
    • 70350434889 scopus 로고    scopus 로고
    • Effective depletion of regulatory T cells allows the recruitment of mesothelin-specific CD8 T cells to the antitumor immune response against a mesothelin-expressing mouse pancreatic adenocarcinoma
    • Leao, I.C.; Ganesan, P.; Armstrong, T.D.; Jaffee, E.M. Effective depletion of regulatory T cells allows the recruitment of mesothelin-specific CD8 T cells to the antitumor immune response against a mesothelin-expressing mouse pancreatic adenocarcinoma. Clin. Transl. Sci. 2008, 1, 228-239.
    • (2008) Clin. Transl. Sci , vol.1 , pp. 228-239
    • Leao, I.C.1    Ganesan, P.2    Armstrong, T.D.3    Jaffee, E.M.4
  • 50
    • 0034653477 scopus 로고    scopus 로고
    • Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: Implications for strategies of chemoimmunotherapy of cancer
    • Schiavoni, G.; Mattei, F.; Di Pucchio, T.; Santini, S.M.; Bracci, L.; Belardelli, F.; Proietti, E. Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: Implications for strategies of chemoimmunotherapy of cancer. Blood 2000, 95, 2024-2030.
    • (2000) Blood , vol.95 , pp. 2024-2030
    • Schiavoni, G.1    Mattei, F.2    di Pucchio, T.3    Santini, S.M.4    Bracci, L.5    Belardelli, F.6    Proietti, E.7
  • 52
    • 77953963578 scopus 로고    scopus 로고
    • A phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma
    • Greten, T.F.; Forner, A.; Korangy, F.; N'Kontchou, G.; Barget, N.; Ayuso, C.; Ormandy, L.A.; Manns, M.P.; Beaugrand, M.; Bruix, J. A phase II open label trial evaluating safety and efficacy of a telomerase peptide vaccination in patients with advanced hepatocellular carcinoma. BMC Cancer 2010, 10, 209.
    • (2010) BMC Cancer , vol.10 , pp. 209
    • Greten, T.F.1    Forner, A.2    Korangy, F.3    N'kontchou, G.4    Barget, N.5    Ayuso, C.6    Ormandy, L.A.7    Manns, M.P.8    Beaugrand, M.9    Bruix, J.10
  • 54
    • 78650371145 scopus 로고    scopus 로고
    • Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immune therapeutic response
    • doi: 10.1158/1078-0432.CCR-10-1693
    • Kong, L.Y.; Wu, A.; Doucette, T.; Wei, J.; Priebe, W.; Fuller, G.N.; Qiao, W.; Sawaya, R.; Rao, G.; Heimberger, A.B. Intratumoral mediated immunosuppression is prognostic in genetically engineered murine models of glioma and correlates to immune therapeutic response. Clin. Cancer. Res. 2010, doi: 10.1158/1078-0432.CCR-10-1693.
    • (2010) Clin. Cancer. Res
    • Kong, L.Y.1    Wu, A.2    Doucette, T.3    Wei, J.4    Priebe, W.5    Fuller, G.N.6    Qiao, W.7    Sawaya, R.8    Rao, G.9    Heimberger, A.B.10
  • 55
    • 77950498254 scopus 로고    scopus 로고
    • Immunogenic chemotherapy with cyclophosphamide and doxorubicin against established murine carcinoma
    • Tongu, M.; Harashima, N.; Yamada, T.; Harada, T.; Harada, M. Immunogenic chemotherapy with cyclophosphamide and doxorubicin against established murine carcinoma. Cancer Immunol. Immunother. 2010, 59, 769-777.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 769-777
    • Tongu, M.1    Harashima, N.2    Yamada, T.3    Harada, T.4    Harada, M.5
  • 56
    • 73349084990 scopus 로고    scopus 로고
    • Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: A chemotherapy dose-ranging factorial study of safety and immune activation
    • Emens, L.A.; Asquith, J.M.; Leatherman, J.M.; Kobrin, B.J.; Petrik, S.; Laiko, M.; Levi, J.; Daphtary, M.M.; Biedrzycki, B.; Wolff, A.C.; et al. Timed sequential treatment with cyclophosphamide, doxorubicin, and an allogeneic granulocyte-macrophage colony-stimulating factor-secreting breast tumor vaccine: a chemotherapy dose-ranging factorial study of safety and immune activation. J. Clin. Oncol. 2009, 27, 5911-5918.
    • (2009) J. Clin. Oncol , vol.27 , pp. 5911-5918
    • Emens, L.A.1    Asquith, J.M.2    Leatherman, J.M.3    Kobrin, B.J.4    Petrik, S.5    Laiko, M.6    Levi, J.7    Daphtary, M.M.8    Biedrzycki, B.9    Wolff, A.C.10
  • 57
    • 0035214416 scopus 로고    scopus 로고
    • Metronomic scheduling: The future of chemotherapy?
    • Gasparini, G. Metronomic scheduling: the future of chemotherapy? Lancet. Oncol. 2001, 2, 733-740.
    • (2001) Lancet. Oncol , vol.2 , pp. 733-740
    • Gasparini, G.1
  • 58
    • 0034032882 scopus 로고    scopus 로고
    • Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drugresistant cancer
    • Browder, T.; Butterfield, C.E.; Kraling, B.M.; Shi, B.; Marshall, B.; O'Reilly, M.S.; Folkman, J. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drugresistant cancer. Cancer Res. 2000, 60, 1878-1886.
    • (2000) Cancer Res , vol.60 , pp. 1878-1886
    • Browder, T.1    Butterfield, C.E.2    Kraling, B.M.3    Shi, B.4    Marshall, B.5    O'Reilly, M.S.6    Folkman, J.7
  • 59
  • 60
    • 74349102406 scopus 로고    scopus 로고
    • Administration of cyclophosphamide changes the immune profile of tumor-bearing mice
    • Liu, P.; Jaffar, J.; Hellstrom, I.; Hellstrom, K.E. Administration of cyclophosphamide changes the immune profile of tumor-bearing mice. J. Immunother. 2010, 33, 53-59.
    • (2010) J. Immunother , vol.33 , pp. 53-59
    • Liu, P.1    Jaffar, J.2    Hellstrom, I.3    Hellstrom, K.E.4
  • 61
    • 77953730756 scopus 로고    scopus 로고
    • + regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels
    • + regulatory T cells by low-dose cyclophosphamide is explained by reduced intracellular ATP levels. Cancer Res. 2010, 70, 4850-4858.
    • (2010) Cancer Res , vol.70 , pp. 4850-4858
    • Zhao, J.1    Cao, Y.2    Lei, Z.3    Yang, Z.4    Zhang, B.5    Huang, B.6
  • 63
    • 67349133537 scopus 로고    scopus 로고
    • Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice
    • Le, H.K.; Graham, L.; Cha, E.; Morales, J.K.; Manjili, M.H.; Bear, H.D. Gemcitabine directly inhibits myeloid derived suppressor cells in BALB/c mice bearing 4T1 mammary carcinoma and augments expansion of T cells from tumor-bearing mice. Int. Immunopharmacol. 2009, 9, 900-909.
    • (2009) Int. Immunopharmacol , vol.9 , pp. 900-909
    • Le, H.K.1    Graham, L.2    Cha, E.3    Morales, J.K.4    Manjili, M.H.5    Bear, H.D.6
  • 64
    • 77951086882 scopus 로고    scopus 로고
    • 5-Fluorouracil selectively kills tumor-associated myeloidderived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
    • Vincent, J.; Mignot, G.; Chalmin, F.; Ladoire, S.; Bruchard, M.; Chevriaux, A.; Martin, F.; Apetoh, L.; Rebe, C.; Ghiringhelli, F. 5-Fluorouracil selectively kills tumor-associated myeloidderived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res. 2010, 70, 3052-3061.
    • (2010) Cancer Res , vol.70 , pp. 3052-3061
    • Vincent, J.1    Mignot, G.2    Chalmin, F.3    Ladoire, S.4    Bruchard, M.5    Chevriaux, A.6    Martin, F.7    Apetoh, L.8    Rebe, C.9    Ghiringhelli, F.10
  • 65
    • 34547630506 scopus 로고    scopus 로고
    • A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model
    • Ko, H.J.; Kim, Y.J.; Kim, Y.S.; Chang, W.S.; Ko, S.Y.; Chang, S.Y.; Sakaguchi, S.; Kang, C.Y. A combination of chemoimmunotherapies can efficiently break self-tolerance and induce antitumor immunity in a tolerogenic murine tumor model. Cancer Res. 2007, 67, 7477-7486.
    • (2007) Cancer Res , vol.67 , pp. 7477-7486
    • Ko, H.J.1    Kim, Y.J.2    Kim, Y.S.3    Chang, W.S.4    Ko, S.Y.5    Chang, S.Y.6    Sakaguchi, S.7    Kang, C.Y.8
  • 66
    • 79959733137 scopus 로고    scopus 로고
    • Gemcitabine depletes regulatory T-cells in human and mice and enhances triggering of vaccine-specific cytotoxic T-cells
    • Rettig, L.; Seidenberg, S.; Parvanova, I.; Samaras, P.; Knuth, A.; Pascolo, S. Gemcitabine depletes regulatory T-cells in human and mice and enhances triggering of vaccine-specific cytotoxic T-cells. Int. J. Cancer 2010, 129, 832-838.
    • (2010) Int. J. Cancer , vol.129 , pp. 832-838
    • Rettig, L.1    Seidenberg, S.2    Parvanova, I.3    Samaras, P.4    Knuth, A.5    Pascolo, S.6
  • 67
    • 77952585049 scopus 로고    scopus 로고
    • Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC)
    • Correale, P.; Marra, M.; Remondo, C.; Migali, C.; Misso, G.; Arcuri, F.P.; Del Vecchio, M.T.; Carducci, A.; Loiacono, L.; Tassone, P.; et al. Cytotoxic drugs up-regulate epidermal growth factor receptor (EGFR) expression in colon cancer cells and enhance their susceptibility to EGFR-targeted antibody-dependent cell-mediated-cytotoxicity (ADCC). Eur. J. Cancer 2010, 46, 1703-1711.
    • (2010) Eur. J. Cancer , vol.46 , pp. 1703-1711
    • Correale, P.1    Marra, M.2    Remondo, C.3    Migali, C.4    Misso, G.5    Arcuri, F.P.6    Del Vecchio, M.T.7    Carducci, A.8    Loiacono, L.9    Tassone, P.10
  • 68
    • 0037457485 scopus 로고    scopus 로고
    • Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLAA() 02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro
    • Correale, P.; Aquino, A.; Giuliani, A.; Pellegrini, M.; Micheli, L.; Cusi, M.G.; Nencini, C.; Petrioli, R.; Prete, S.P.; De Vecchis, L. et al. Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLAA() 02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro. Int. J. Cancer 2003, 104, 437-445.
    • (2003) Int. J. Cancer , vol.104 , pp. 437-445
    • Correale, P.1    Aquino, A.2    Giuliani, A.3    Pellegrini, M.4    Micheli, L.5    Cusi, M.G.6    Nencini, C.7    Petrioli, R.8    Prete, S.P.9    de Vecchis, L.10
  • 71
    • 77953134540 scopus 로고    scopus 로고
    • Metronomic chemotherapy enhances antitumor effects of cancer vaccine by depleting regulatory T lymphocytes and inhibiting tumor angiogenesis
    • Chen, C.A.; Ho, C.M.; Chang, M.C.; Sun, W.Z.; Chen, Y.L.; Chiang, Y.C.; Syu, M.H.; Hsieh, C.Y.; Cheng, W.F. Metronomic chemotherapy enhances antitumor effects of cancer vaccine by depleting regulatory T lymphocytes and inhibiting tumor angiogenesis. Mol. Ther. 2010, 18, 1233-1243.
    • (2010) Mol. Ther , vol.18 , pp. 1233-1243
    • Chen, C.A.1    Ho, C.M.2    Chang, M.C.3    Sun, W.Z.4    Chen, Y.L.5    Chiang, Y.C.6    Syu, M.H.7    Hsieh, C.Y.8    Cheng, W.F.9
  • 72
    • 68349123372 scopus 로고    scopus 로고
    • Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12- dependent mechanism
    • Shurin, G.V.; Tourkova, I.L.; Kaneno, R.; Shurin, M.R. Chemotherapeutic agents in noncytotoxic concentrations increase antigen presentation by dendritic cells via an IL-12- dependent mechanism. J. Immunol. 2009, 183, 137-144.
    • (2009) J. Immunol , vol.183 , pp. 137-144
    • Shurin, G.V.1    Tourkova, I.L.2    Kaneno, R.3    Shurin, M.R.4
  • 73
    • 77952549994 scopus 로고    scopus 로고
    • Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice
    • Pfannenstiel, L.W.; Lam, S.S.; Emens, L.A.; Jaffee, E.M.; Armstrong, T.D. Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice. Cell Immunol. 2010, 263, 79-87.
    • (2010) Cell Immunol , vol.263 , pp. 79-87
    • Pfannenstiel, L.W.1    Lam, S.S.2    Emens, L.A.3    Jaffee, E.M.4    Armstrong, T.D.5
  • 75
    • 79953832076 scopus 로고    scopus 로고
    • Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer
    • Ramakrishnan, R.; Gabrilovich, D.I. Mechanism of synergistic effect of chemotherapy and immunotherapy of cancer. Cancer Immunol. Immunother. 2011, 60, 419-423.
    • (2011) Cancer Immunol. Immunother , vol.60 , pp. 419-423
    • Ramakrishnan, R.1    Gabrilovich, D.I.2
  • 76
    • 34848879000 scopus 로고    scopus 로고
    • Low-dose paclitaxel prior to intratumoral dendritic cell vaccine modulates intratumoral cytokine network and lung cancer growth
    • Zhong, H.; Han, B.; Tourkova, I.L.; Lokshin, A.; Rosenbloom, A.; Shurin, M.R.; Shurin, G.V. Low-dose paclitaxel prior to intratumoral dendritic cell vaccine modulates intratumoral cytokine network and lung cancer growth. Clin. Cancer Res. 2007, 13, 5455-5462.
    • (2007) Clin. Cancer Res , vol.13 , pp. 5455-5462
    • Zhong, H.1    Han, B.2    Tourkova, I.L.3    Lokshin, A.4    Rosenbloom, A.5    Shurin, M.R.6    Shurin, G.V.7
  • 77
    • 0037239826 scopus 로고    scopus 로고
    • Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer
    • Yu, B.; Kusmartsev, S.; Cheng, F.; Paolini, M.; Nefedova, Y.; Sotomayor, E.; Gabrilovich, D. Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer. Clin. Cancer Res. 2003, 9, 285-294.
    • (2003) Clin. Cancer Res , vol.9 , pp. 285-294
    • Yu, B.1    Kusmartsev, S.2    Cheng, F.3    Paolini, M.4    Nefedova, Y.5    Sotomayor, E.6    Gabrilovich, D.7
  • 78
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • Machiels, J.P.; Reilly, R.T.; Emens, L.A.; Ercolini, A.M.; Lei, R.Y.; Weintraub, D.; Okoye, F.I.; Jaffee, E.M. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res. 2001, 61, 3689-3697.
    • (2001) Cancer Res , vol.61 , pp. 3689-3697
    • Machiels, J.P.1    Reilly, R.T.2    Emens, L.A.3    Ercolini, A.M.4    Lei, R.Y.5    Weintraub, D.6    Okoye, F.I.7    Jaffee, E.M.8
  • 79
    • 72449150594 scopus 로고    scopus 로고
    • Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice
    • Jiang, H.; Tao, W.; Zhang, M.; Pan, S.; Kanwar, J.R.; Sun, X. Low-dose metronomic paclitaxel chemotherapy suppresses breast tumors and metastases in mice. Cancer Invest. 2010, 28, 74-84.
    • (2010) Cancer Invest , vol.28 , pp. 74-84
    • Jiang, H.1    Tao, W.2    Zhang, M.3    Pan, S.4    Kanwar, J.R.5    Sun, X.6
  • 80
    • 67651027346 scopus 로고    scopus 로고
    • Weekly low-dose paclitaxel as maintenance treatment in patients with advanced ovarian cancer who had microscopic residual disease at second-look surgery after 6 cycles of paclitaxel/platinum-based chemotherapy: Results of an open noncomparative phase 2 multicenter Italian study (After-6 Protocol 2)
    • Gadducci, A.; Katsaros, D.; Zola, P.; Scambia, G.; Ballardini, M.; Pasquini, E.; Fertonani, C.; Maggi, L.; Pecorelli, S.; Conte, P.F. Weekly low-dose paclitaxel as maintenance treatment in patients with advanced ovarian cancer who had microscopic residual disease at second-look surgery after 6 cycles of paclitaxel/platinum-based chemotherapy: results of an open noncomparative phase 2 multicenter Italian study (After-6 Protocol 2). Int. J. Gynecol. Cancer 2009, 19, 615-619.
    • (2009) Int. J. Gynecol. Cancer , vol.19 , pp. 615-619
    • Gadducci, A.1    Katsaros, D.2    Zola, P.3    Scambia, G.4    Ballardini, M.5    Pasquini, E.6    Fertonani, C.7    Maggi, L.8    Pecorelli, S.9    Conte, P.F.10
  • 81
    • 77950243302 scopus 로고    scopus 로고
    • A phase 2 pilot trial of low-dose, continuous infusion, or metronomic paclitaxel and oral celecoxib in patients with metastatic melanoma
    • Bhatt, R.S.; Merchan, J.; Parker, R.; Wu, H.K.; Zhang, L.; Seery, V.; Heymach, J.V.; Atkins, M.B.; McDermott, D.; Sukhatme, V.P. A phase 2 pilot trial of low-dose, continuous infusion, or metronomic paclitaxel and oral celecoxib in patients with metastatic melanoma. Cancer 2010, 116, 1751-1756.
    • (2010) Cancer , vol.116 , pp. 1751-1756
    • Bhatt, R.S.1    Merchan, J.2    Parker, R.3    Wu, H.K.4    Zhang, L.5    Seery, V.6    Heymach, J.V.7    Atkins, M.B.8    McDermott, D.9    Sukhatme, V.P.10
  • 83
    • 0347949497 scopus 로고    scopus 로고
    • Primary ovarian cancer chemotherapy: Current standards of care
    • McGuire, W.P., 3rd; Markman, M. Primary ovarian cancer chemotherapy: Current standards of care. Br. J. Cancer 2003, 89 Suppl. 3, S3-S8.
    • (2003) Br. J. Cancer , vol.89 , Issue.SUPPL. 3
    • McGuire III, W.P.1    Markman, M.2
  • 84
    • 0035183168 scopus 로고    scopus 로고
    • Platinum compounds in the treatment of advanced breast cancer
    • Martin, M. Platinum compounds in the treatment of advanced breast cancer. Clin. Breast Cancer 2001, 2, 190-209.
    • (2001) Clin. Breast Cancer , vol.2 , pp. 190-209
    • Martin, M.1
  • 87
    • 71849088755 scopus 로고    scopus 로고
    • The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy
    • Wu, X.; Feng, Q.M.; Wang, Y.; Shi, J.; Ge, H.L.; Di, W. The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy. Cancer Immunol. Immunother. 2010, 59, 279-291.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 279-291
    • Wu, X.1    Feng, Q.M.2    Wang, Y.3    Shi, J.4    Ge, H.L.5    Di, W.6
  • 88
    • 79958046675 scopus 로고    scopus 로고
    • Preconditioning chemotherapy with paclitaxel and cisplatin enhances the antitumor activity of cytokine induced-killer cells in a murine lung carcinoma model
    • Huang, X.; Huang, G.; Song, H.; Chen, L. Preconditioning chemotherapy with paclitaxel and cisplatin enhances the antitumor activity of cytokine induced-killer cells in a murine lung carcinoma model. Int. J. Cancer 2011, 129, 648-658.
    • (2011) Int. J. Cancer , vol.129 , pp. 648-658
    • Huang, X.1    Huang, G.2    Song, H.3    Chen, L.4
  • 89
    • 79960329487 scopus 로고    scopus 로고
    • Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients
    • Kyte, J.A.; Gaudernack, G.; Dueland, S.; Trachsel, S.; Julsrud, L.; Aamdal, S. Telomerase Peptide Vaccination Combined with Temozolomide: A Clinical Trial in Stage IV Melanoma Patients. Clin. Cancer Res. 2011, 17, 4568-4580.
    • (2011) Clin. Cancer Res , vol.17 , pp. 4568-4580
    • Kyte, J.A.1    Gaudernack, G.2    Dueland, S.3    Trachsel, S.4    Julsrud, L.5    Aamdal, S.6
  • 90
    • 79960706708 scopus 로고    scopus 로고
    • Randomized Multicenter Trial of the Effects of Melanoma- Associated Helper Peptides and Cyclophosphamide on the Immunogenicity of a Multipeptide Melanoma Vaccine
    • doi: 10.1200/JCO.2010.33.8053
    • Slingluff, C.L., Jr.; Petroni, G.R.; Chianese-Bullock, K.A.; Smolkin, M.E.; Ross, M.I.; Haas, N.B.; von Mehren, M.; Grosh, W.W. Randomized Multicenter Trial of the Effects of Melanoma- Associated Helper Peptides and Cyclophosphamide on the Immunogenicity of a Multipeptide Melanoma Vaccine. J. Clin. Oncol. 2011, doi: 10.1200/JCO.2010.33.8053.
    • (2011) J. Clin. Oncol
    • Slingluff Jr., C.L.1    Petroni, G.R.2    Chianese-Bullock, K.A.3    Smolkin, M.E.4    Ross, M.I.5    Haas, N.B.6    von Mehren, M.7    Grosh, W.W.8
  • 93
    • 77956920709 scopus 로고    scopus 로고
    • Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients
    • Palermo, B.; Del Bello, D.; Sottini, A.; Serana, F.; Ghidini, C.; Gualtieri, N.; Ferraresi, V.; Catricala, C.; Belardelli, F.; Proietti, E. et al. Dacarbazine treatment before peptide vaccination enlarges T-cell repertoire diversity of melan-a-specific, tumor-reactive CTL in melanoma patients. Cancer Res. 2010, 70, 7084-7092.
    • (2010) Cancer Res , vol.70 , pp. 7084-7092
    • Palermo, B.1    del Bello, D.2    Sottini, A.3    Serana, F.4    Ghidini, C.5    Gualtieri, N.6    Ferraresi, V.7    Catricala, C.8    Belardelli, F.9    Proietti, E.10
  • 94
    • 77956310379 scopus 로고    scopus 로고
    • A phase II study of personalized peptide vaccination combined with gemcitabine for non-resectable pancreatic cancer patients
    • Yanagimoto, H.; Shiomi, H.; Satoi, S.; Mine, T.; Toyokawa, H.; Yamamoto, T.; Tani, T.; Yamada, A.; Kwon, A.H.; Komatsu, N. et al. A phase II study of personalized peptide vaccination combined with gemcitabine for non-resectable pancreatic cancer patients. Oncol. Rep. 2010, 24, 795-801.
    • (2010) Oncol. Rep , vol.24 , pp. 795-801
    • Yanagimoto, H.1    Shiomi, H.2    Satoi, S.3    Mine, T.4    Toyokawa, H.5    Yamamoto, T.6    Tani, T.7    Yamada, A.8    Kwon, A.H.9    Komatsu, N.10
  • 96
    • 50349090322 scopus 로고    scopus 로고
    • A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer
    • Ramlau, R.; Quoix, E.; Rolski, J.; Pless, M.; Lena, H.; Levy, E.; Krzakowski, M.; Hess, D.; Tartour, E.; Chenard, M.P. et al. A phase II study of Tg4010 (Mva-Muc1-Il2) in association with chemotherapy in patients with stage III/IV Non-small cell lung cancer. J. Thorac. Oncol. 2008, 3, 735-744.
    • (2008) J. Thorac. Oncol , vol.3 , pp. 735-744
    • Ramlau, R.1    Quoix, E.2    Rolski, J.3    Pless, M.4    Lena, H.5    Levy, E.6    Krzakowski, M.7    Hess, D.8    Tartour, E.9    Chenard, M.P.10
  • 98
    • 78650667121 scopus 로고    scopus 로고
    • Phase 1 trial of Wilms tumor 1 (WT1) peptide vaccine and gemcitabine combination therapy in patients with advanced pancreatic or biliary tract cancer
    • Kaida, M.; Morita-Hoshi, Y.; Soeda, A.; Wakeda, T.; Yamaki, Y.; Kojima, Y.; Ueno, H.; Kondo, S.; Morizane, C.; Ikeda, M. et al. Phase 1 trial of Wilms tumor 1 (WT1) peptide vaccine and gemcitabine combination therapy in patients with advanced pancreatic or biliary tract cancer. J. Immunother. 2011, 34, 92-99.
    • (2011) J. Immunother , vol.34 , pp. 92-99
    • Kaida, M.1    Morita-Hoshi, Y.2    Soeda, A.3    Wakeda, T.4    Yamaki, Y.5    Kojima, Y.6    Ueno, H.7    Kondo, S.8    Morizane, C.9    Ikeda, M.10
  • 99
    • 79955862560 scopus 로고    scopus 로고
    • Safety of BLP25 liposome vaccine (L-BLP25) in Japanese patients with unresectable stage III NSCLC after primary chemoradiotherapy: Preliminary results from a Phase I/II study
    • Ohyanagi, F.; Horai, T.; Sekine, I.; Yamamoto, N.; Nakagawa, K.; Nishio, M.; Senger, S.; Morsli, N.; Tamura, T. Safety of BLP25 liposome vaccine (L-BLP25) in Japanese patients with unresectable stage III NSCLC after primary chemoradiotherapy: preliminary results from a Phase I/II study. Jpn. J. Clin. Oncol. 2011, 41, 718-722.
    • (2011) Jpn. J. Clin. Oncol , vol.41 , pp. 718-722
    • Ohyanagi, F.1    Horai, T.2    Sekine, I.3    Yamamoto, N.4    Nakagawa, K.5    Nishio, M.6    Senger, S.7    Morsli, N.8    Tamura, T.9
  • 100
    • 77953040440 scopus 로고    scopus 로고
    • A randomized phase II trial of personalized peptide vaccine plus low dose estramustine phosphate (EMP) versus standard dose EMP in patients with castration resistant prostate cancer
    • Noguchi, M.; Kakuma, T.; Uemura, H.; Nasu, Y.; Kumon, H.; Hirao, Y.; Moriya, F.; Suekane, S.; Matsuoka, K.; Komatsu, N. et al. A randomized phase II trial of personalized peptide vaccine plus low dose estramustine phosphate (EMP) versus standard dose EMP in patients with castration resistant prostate cancer. Cancer Immunol. Immunother. 2010, 59, 1001-1009.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 1001-1009
    • Noguchi, M.1    Kakuma, T.2    Uemura, H.3    Nasu, Y.4    Kumon, H.5    Hirao, Y.6    Moriya, F.7    Suekane, S.8    Matsuoka, K.9    Komatsu, N.10
  • 105
    • 0036105153 scopus 로고    scopus 로고
    • Survivin-A universal tumor antigen
    • Andersen, M.H.; thor, S.P. Survivin-A universal tumor antigen. Histol. Histopathol. 2002, 17, 669-675.
    • (2002) Histol. Histopathol , vol.17 , pp. 669-675
    • Andersen, M.H.1    Thor, S.P.2
  • 106
    • 77956680686 scopus 로고    scopus 로고
    • Survivin and IAP proteins in cell-death mechanisms
    • Altieri, D.C. Survivin and IAP proteins in cell-death mechanisms. Biochem. J. 2010, 430, 199-205.
    • (2010) Biochem. J , vol.430 , pp. 199-205
    • Altieri, D.C.1
  • 107
    • 74949136580 scopus 로고    scopus 로고
    • Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies
    • Campoli, M.; Ferris, R.; Ferrone, S.; Wang, X. Immunotherapy of malignant disease with tumor antigen-specific monoclonal antibodies. Clin. Cancer Res. 2010, 16, 11-20.
    • (2010) Clin. Cancer Res , vol.16 , pp. 11-20
    • Campoli, M.1    Ferris, R.2    Ferrone, S.3    Wang, X.4
  • 108
    • 0036307752 scopus 로고    scopus 로고
    • Immune complex-mediated antigen presentation induces tumor immunity
    • Rafiq, K.; Bergtold, A.; Clynes, R. Immune complex-mediated antigen presentation induces tumor immunity. J. Clin. Invest. 2002, 110, 71-79.
    • (2002) J. Clin. Invest , vol.110 , pp. 71-79
    • Rafiq, K.1    Bergtold, A.2    Clynes, R.3
  • 109
    • 74949116624 scopus 로고    scopus 로고
    • Immunotherapy of malignant disease: The coming age of therapeutic monoclonal antibodies
    • DeVita, V., Hellman, S., Rosenberg, S., Eds; Lippincott Williams and Wilkins: New York, NY, USA
    • Campoli, M.; Ferrone, S. Immunotherapy of malignant disease: The coming age of therapeutic monoclonal antibodies. In Cancer: Principles & Practive of Oncology; DeVita, V., Hellman, S., Rosenberg, S., Eds; Lippincott Williams and Wilkins: New York, NY, USA, 2009; pp. 1-18.
    • (2009) Cancer: Principles & Practive of Oncology , pp. 1-18
    • Campoli, M.1    Ferrone, S.2
  • 110
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: Versatile platforms for cancer immunotherapy
    • Weiner, L.M.; Surana, R.; Wang, S. Monoclonal antibodies: Versatile platforms for cancer immunotherapy. Nat. Rev. Immunol. 2010, 10, 317-327.
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 317-327
    • Weiner, L.M.1    Surana, R.2    Wang, S.3
  • 112
    • 0036214017 scopus 로고    scopus 로고
    • The B7 family of ligands and its receptors: New pathways for costimulation and inhibition of immune responses
    • Carreno, B.M.; Collins, M. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. Annu. Rev. Immunol. 2002, 20, 29-53.
    • (2002) Annu. Rev. Immunol , vol.20 , pp. 29-53
    • Carreno, B.M.1    Collins, M.2
  • 113
    • 68149155982 scopus 로고    scopus 로고
    • Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti- CTLA-4 antibodies
    • Peggs, K.S.; Quezada, S.A.; Chambers, C.A.; Korman, A.J.; Allison, J.P. Blockade of CTLA-4 on both effector and regulatory T cell compartments contributes to the antitumor activity of anti- CTLA-4 antibodies. J. Exp. Med. 2009, 206, 1717-1725.
    • (2009) J. Exp. Med , vol.206 , pp. 1717-1725
    • Peggs, K.S.1    Quezada, S.A.2    Chambers, C.A.3    Korman, A.J.4    Allison, J.P.5
  • 114
    • 28244492012 scopus 로고    scopus 로고
    • Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade
    • Maker, A.V.; Attia, P.; Rosenberg, S.A. Analysis of the cellular mechanism of antitumor responses and autoimmunity in patients treated with CTLA-4 blockade. J. Immunol. 2005, 175, 7746-7754.
    • (2005) J. Immunol , vol.175 , pp. 7746-7754
    • Maker, A.V.1    Attia, P.2    Rosenberg, S.A.3
  • 115
    • 77953378992 scopus 로고    scopus 로고
    • CTLA-4 blockade: Therapeutic potential in cancer treatments
    • Tarhini, A.A.; Iqbal, F. CTLA-4 blockade: Therapeutic potential in cancer treatments. Onco. Targets. Ther. 2010, 3, 15-25.
    • (2010) Onco. Targets. Ther , vol.3 , pp. 15-25
    • Tarhini, A.A.1    Iqbal, F.2
  • 116
    • 78449250123 scopus 로고    scopus 로고
    • Clinical Development of the Anti-CTLA-4 Antibody Tremelimumab
    • Ribas, A. Clinical Development of the Anti-CTLA-4 Antibody Tremelimumab. Semin. Oncol. 2010, 37, 450-454.
    • (2010) Semin. Oncol , vol.37 , pp. 450-454
    • Ribas, A.1
  • 118
    • 77955874663 scopus 로고    scopus 로고
    • Treating cancer by targeting the immune system
    • Hwu, P. Treating cancer by targeting the immune system. N. Engl. J. Med. 2010, 363, 779-781.
    • (2010) N. Engl. J. Med , vol.363 , pp. 779-781
    • Hwu, P.1
  • 120
    • 77957355380 scopus 로고    scopus 로고
    • Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A 2402
    • Baba, T.; Sato-Matsushita, M.; Kanamoto, A.; Itoh, A.; Oyaizu, N.; Inoue, Y.; Kawakami, Y.; Tahara, H. Phase I clinical trial of the vaccination for the patients with metastatic melanoma using gp100-derived epitope peptide restricted to HLA-A 2402. J. Transl. Med. 2010, 8, 84.
    • (2010) J. Transl. Med , vol.8 , pp. 84
    • Baba, T.1    Sato-Matsushita, M.2    Kanamoto, A.3    Itoh, A.4    Oyaizu, N.5    Inoue, Y.6    Kawakami, Y.7    Tahara, H.8
  • 121
    • 29844436043 scopus 로고    scopus 로고
    • The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling
    • Met, O.; Wang, M.; Pedersen, A.E.; Nissen, M.H.; Buus, S.; Claesson, M.H. The effect of a therapeutic dendritic cell-based cancer vaccination depends on the blockage of CTLA-4 signaling. Cancer Lett. 2006, 231, 247-256.
    • (2006) Cancer Lett , vol.231 , pp. 247-256
    • Met, O.1    Wang, M.2    Pedersen, A.E.3    Nissen, M.H.4    Buus, S.5    Claesson, M.H.6
  • 122
    • 35248897095 scopus 로고    scopus 로고
    • Synergistic antitumor effect of chemotactic-prostate tumor-associated antigen gene-modified tumor cell vaccine and anti-CTLA-4 mAb in murine tumor model
    • Li, N.; Qin, H.; Li, X.; Zhou, C.; Wang, D.; Ma, W.; Lin, C.; Zhang, Y.; Wang, S.; Zhang, S. Synergistic antitumor effect of chemotactic-prostate tumor-associated antigen gene-modified tumor cell vaccine and anti-CTLA-4 mAb in murine tumor model. Immunol. Lett. 2007, 113, 90-98.
    • (2007) Immunol. Lett , vol.113 , pp. 90-98
    • Li, N.1    Qin, H.2    Li, X.3    Zhou, C.4    Wang, D.5    Ma, W.6    Lin, C.7    Zhang, Y.8    Wang, S.9    Zhang, S.10
  • 123
    • 34347398452 scopus 로고    scopus 로고
    • The combined activation of positive costimulatory signals with modulation of a negative costimulatory signal for the enhancement of vaccinemediated T-cell responses
    • Chakraborty, M.; Schlom, J.; Hodge, J.W. The combined activation of positive costimulatory signals with modulation of a negative costimulatory signal for the enhancement of vaccinemediated T-cell responses. Cancer Immunol. Immunother. 2007, 56, 1471-1484.
    • (2007) Cancer Immunol. Immunother , vol.56 , pp. 1471-1484
    • Chakraborty, M.1    Schlom, J.2    Hodge, J.W.3
  • 125
    • 20244384862 scopus 로고    scopus 로고
    • Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer
    • Ohigashi, Y.; Sho, M.; Yamada, Y.; Tsurui, Y.; Hamada, K.; Ikeda, N.; Mizuno, T.; Yoriki, R.; Kashizuka, H.; Yane, K. et al. Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer. Clin. Cancer Res. 2005, 11, 2947-2953.
    • (2005) Clin. Cancer Res , vol.11 , pp. 2947-2953
    • Ohigashi, Y.1    Sho, M.2    Yamada, Y.3    Tsurui, Y.4    Hamada, K.5    Ikeda, N.6    Mizuno, T.7    Yoriki, R.8    Kashizuka, H.9    Yane, K.10
  • 126
    • 33745491116 scopus 로고    scopus 로고
    • Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance
    • Wu, C.; Zhu, Y.; Jiang, J.; Zhao, J.; Zhang, X.G.; Xu, N. Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance. Acta Histochem. 2006, 108, 19-24.
    • (2006) Acta Histochem , vol.108 , pp. 19-24
    • Wu, C.1    Zhu, Y.2    Jiang, J.3    Zhao, J.4    Zhang, X.G.5    Xu, N.6
  • 127
    • 78449243489 scopus 로고    scopus 로고
    • Immune Checkpoint Proteins: A New Therapeutic Paradigm for Cancer-Preclinical Background: CTLA-4 and PD-1 Blockade
    • Weber, J. Immune Checkpoint Proteins: A New Therapeutic Paradigm for Cancer-Preclinical Background: CTLA-4 and PD-1 Blockade. Semin. Oncol. 2010, 37, 430-439.
    • (2010) Semin. Oncol , vol.37 , pp. 430-439
    • Weber, J.1
  • 130
    • 63449124514 scopus 로고    scopus 로고
    • Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor--secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors
    • Li, B.; VanRoey, M.; Wang, C.; Chen, T.H.; Korman, A.; Jooss, K. Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor--secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors. Clin. Cancer. Res. 2009, 15, 1623-1634.
    • (2009) Clin. Cancer. Res , vol.15 , pp. 1623-1634
    • Li, B.1    Vanroey, M.2    Wang, C.3    Chen, T.H.4    Korman, A.5    Jooss, K.6
  • 132
    • 77749279776 scopus 로고    scopus 로고
    • PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
    • Curran, M.A.; Montalvo, W.; Yagita, H.; Allison, J.P. PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors. Proc. Natl. Acad. Sci. USA 2010, 107, 4275-4280.
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 4275-4280
    • Curran, M.A.1    Montalvo, W.2    Yagita, H.3    Allison, J.P.4
  • 133
    • 77954899030 scopus 로고    scopus 로고
    • Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • Brahmer, J.R.; Drake, C.G.; Wollner, I.; Powderly, J.D.; Picus, J.; Sharfman, W.H.; Stankevich, E.; Pons, A.; Salay, T.M.; McMiller, T.L. et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates. J. Clin. Oncol. 2010, 28, 3167-3175.
    • (2010) J. Clin. Oncol , vol.28 , pp. 3167-3175
    • Brahmer, J.R.1    Drake, C.G.2    Wollner, I.3    Powderly, J.D.4    Picus, J.5    Sharfman, W.H.6    Stankevich, E.7    Pons, A.8    Salay, T.M.9    McMiller, T.L.10
  • 134
    • 61349139964 scopus 로고    scopus 로고
    • Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells
    • Liu, Y.; Yu, Y.; Yang, S.; Zeng, B.; Zhang, Z.; Jiao, G.; Zhang, Y.; Cai, L.; Yang, R. Regulation of arginase I activity and expression by both PD-1 and CTLA-4 on the myeloid-derived suppressor cells. Cancer Immunol. Immunother. 2009, 58, 687-697.
    • (2009) Cancer Immunol. Immunother , vol.58 , pp. 687-697
    • Liu, Y.1    Yu, Y.2    Yang, S.3    Zeng, B.4    Zhang, Z.5    Jiao, G.6    Zhang, Y.7    Cai, L.8    Yang, R.9
  • 136
    • 70350496784 scopus 로고    scopus 로고
    • Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells
    • Rech, A.J.; Vonderheide, R.H. Clinical use of anti-CD25 antibody daclizumab to enhance immune responses to tumor antigen vaccination by targeting regulatory T cells. Ann. N. Y. Acad. Sci. 2009, 1174, 99-106.
    • (2009) Ann. N. Y. Acad. Sci , vol.1174 , pp. 99-106
    • Rech, A.J.1    Vonderheide, R.H.2
  • 138
    • 77955515915 scopus 로고    scopus 로고
    • Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy
    • Coe, D.; Begom, S.; Addey, C.; White, M.; Dyson, J.; Chai, J.G. Depletion of regulatory T cells by anti-GITR mAb as a novel mechanism for cancer immunotherapy. Cancer Immunol. Immunother. 2010, 59, 1367-1377.
    • (2010) Cancer Immunol. Immunother , vol.59 , pp. 1367-1377
    • Coe, D.1    Begom, S.2    Addey, C.3    White, M.4    Dyson, J.5    Chai, J.G.6
  • 139
    • 77955279163 scopus 로고    scopus 로고
    • Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation
    • Cohen, A.D.; Schaer, D.A.; Liu, C.; Li, Y.; Hirschhorn-Cymmerman, D.; Kim, S.C.; Diab, A.; Rizzuto, G.; Duan, F.; Perales, M.A. et al. Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. PLoS One 2010, 5, e10436.
    • (2010) PLoS One , vol.5
    • Cohen, A.D.1    Schaer, D.A.2    Liu, C.3    Li, Y.4    Hirschhorn-Cymmerman, D.5    Kim, S.C.6    Diab, A.7    Rizzuto, G.8    Duan, F.9    Perales, M.A.10
  • 143
    • 73949121455 scopus 로고    scopus 로고
    • Plasticity of T-cell phenotype and function: The T helper type 17 example
    • Peck, A.; Mellins, E.D. Plasticity of T-cell phenotype and function: The T helper type 17 example. Immunology 2010, 129, 147-153.
    • (2010) Immunology , vol.129 , pp. 147-153
    • Peck, A.1    Mellins, E.D.2


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