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Volumn 25, Issue 6, 2013, Pages 602-608

Immunotherapeutics for breast cancer

Author keywords

breast cancer; immunotherapy; tumor infiltrating lymphocytes

Indexed keywords

ALKYLATING AGENT; ANTHRACYCLINE; ANTIGEN; ANTIMETABOLITE; CANCER VACCINE; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DOCETAXEL; DOXORUBICIN; FLUOROURACIL; GEMCITABINE; GLUCOCORTICOID; METHOTREXATE; MONOCLONAL ANTIBODY; OXALIPLATIN; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN TYROSINE KINASE INHIBITOR; TAXANE DERIVATIVE; TRASTUZUMAB;

EID: 84885420987     PISSN: 10408746     EISSN: 1531703X     Source Type: Journal    
DOI: 10.1097/CCO.0000000000000020     Document Type: Review
Times cited : (31)

References (65)
  • 1
    • 78149432308 scopus 로고    scopus 로고
    • Immune regulation of cancer
    • Disis ML. Immune regulation of cancer. J Clin Oncol 2010; 28:4531-4538.
    • (2010) J Clin Oncol , vol.28 , pp. 4531-4538
    • Disis, M.L.1
  • 2
    • 79953151458 scopus 로고    scopus 로고
    • Cancer immunoediting: Integrating immunity's roles in cancer suppression and promotion
    • Schreiber RD, Old LJ, Smyth MJ. Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 2011; 331:1565-1570.
    • (2011) Science , vol.331 , pp. 1565-1570
    • Schreiber, R.D.1    Old, L.J.2    Smyth, M.J.3
  • 4
    • 55249125754 scopus 로고    scopus 로고
    • Interaction of current cancer treatments and the immune system: Implications for breast cancer therapeutics
    • Tan PH, Lota AS. Interaction of current cancer treatments and the immune system: implications for breast cancer therapeutics. Expert Opin Pharmac-other 2008; 9:2639-2660.
    • (2008) Expert Opin Pharmac-other , vol.9 , pp. 2639-2660
    • Tan, P.H.1    Lota, A.S.2
  • 6
    • 79952390627 scopus 로고    scopus 로고
    • Immune parameters affecting the efficacy of chemotherapeutic regimens
    • Zitvogel L, Kepp O, Kroemer G. Immune parameters affecting the efficacy of chemotherapeutic regimens. Nat Rev Clin Oncol 2011; 8:151-160.
    • (2011) Nat Rev Clin Oncol , vol.8 , pp. 151-160
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 7
    • 45749134564 scopus 로고    scopus 로고
    • The anticancer immune response: Indispensable for therapeutic success?
    • Zitvogel L, Apetoh L, Ghiringhelli F, et al. The anticancer immune response: indispensable for therapeutic success? J Clin Investig 2008; 118:1991-2001.
    • (2008) J Clin Investig , vol.118 , pp. 1991-2001
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3
  • 8
    • 18344375283 scopus 로고    scopus 로고
    • Immunotherapy and chemotherapy: A practical partnership
    • Lake RA, Robinson BW. Immunotherapy and chemotherapy: a practical partnership. Nat Rev Cancer 2005; 5:397-405.
    • (2005) Nat Rev Cancer , vol.5 , pp. 397-405
    • Lake, R.A.1    Robinson, B.W.2
  • 9
    • 37349062063 scopus 로고    scopus 로고
    • Decoding dangerous death: How cytotoxic chemotherapy invokes inflammation, immunity or nothing at all
    • van der Most RG, Currie AJ, Robinson BW, Lake RA. Decoding dangerous death: how cytotoxic chemotherapy invokes inflammation, immunity or nothing at all. Cell Death Differ 2008; 15:13-20.
    • (2008) Cell Death Differ , vol.15 , pp. 13-20
    • Van Der Most, R.G.1    Currie, A.J.2    Robinson, B.W.3    Lake, R.A.4
  • 10
    • 34948820602 scopus 로고    scopus 로고
    • Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy
    • Apetoh L, Ghiringhelli F, Tesniere A, et al. Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy. Nat Med 2007; 13:1050-1059.
    • (2007) Nat Med , vol.13 , pp. 1050-1059
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3
  • 11
    • 33846057130 scopus 로고    scopus 로고
    • Calreticulin exposure dictates the immunogenicity of cancer cell death
    • Obeid M, Tesniere A, Ghiringhelli F, et al. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nat Med 2007; 13:54-61.
    • (2007) Nat Med , vol.13 , pp. 54-61
    • Obeid, M.1    Tesniere, A.2    Ghiringhelli, F.3
  • 12
    • 35748942876 scopus 로고    scopus 로고
    • The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy
    • Apetoh L, Ghiringhelli F, Tesniere A, et al. The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy. Immunol Rev 2007; 220:47-59.
    • (2007) Immunol Rev , vol.220 , pp. 47-59
    • Apetoh, L.1    Ghiringhelli, F.2    Tesniere, A.3
  • 13
    • 29144530630 scopus 로고    scopus 로고
    • Caspase-dependent immuno-genicity of doxorubicin-induced tumor cell death
    • Casares N, Pequignot MO, Tesniere A, et al. Caspase-dependent immuno-genicity of doxorubicin-induced tumor cell death. J Exp Med 2005; 202:1691-1701.
    • (2005) J Exp Med , vol.202 , pp. 1691-1701
    • Casares, N.1    Pequignot, M.O.2    Tesniere, A.3
  • 14
    • 79960426821 scopus 로고    scopus 로고
    • Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors
    • Mattarollo SR, Loi S, Duret H, et al. Pivotal role of innate and adaptive immunity in anthracycline chemotherapy of established tumors. Cancer Res 2011; 71:4809-4820.
    • (2011) Cancer Res , vol.71 , pp. 4809-4820
    • Mattarollo, S.R.1    Loi, S.2    Duret, H.3
  • 15
    • 77950366886 scopus 로고    scopus 로고
    • Decoding cell death signals in inflammation and immunity
    • Zitvogel L, Kepp O, Kroemer G. Decoding cell death signals in inflammation and immunity. Cell; 140:798-804.
    • Cell , vol.140 , pp. 798-804
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3
  • 17
    • 0022971313 scopus 로고
    • The effect of adjuvant cyclophosphamide or tamoxifen on the numbers of lymphocytes bearing T cell or NK cell markers
    • Sheard CR, Reilly F, Tee DE, et al. The effect of adjuvant cyclophosphamide or tamoxifen on the numbers of lymphocytes bearing T cell or NK cell markers. Br J Cancer 1986; 54:705-709.
    • (1986) Br J Cancer , vol.54 , pp. 705-709
    • Sheard, C.R.1    Reilly, F.2    Tee, D.E.3
  • 18
    • 0023567954 scopus 로고
    • Immunomodulation by cancer chemotherapeutic agents
    • Periti P, Mini E. Immunomodulation by cancer chemotherapeutic agents. Chemioterapia 1987; 6:399-402.
    • (1987) Chemioterapia , vol.6 , pp. 399-402
    • Periti, P.1    Mini, E.2
  • 19
    • 33746847266 scopus 로고    scopus 로고
    • Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors
    • Rozkova D, Horvath R, Bartunkova J, Spisek R. Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors. Clin Immunol 2006; 120:260-271.
    • (2006) Clin Immunol , vol.120 , pp. 260-271
    • Rozkova, D.1    Horvath, R.2    Bartunkova, J.3    Spisek, R.4
  • 20
    • 33947379469 scopus 로고    scopus 로고
    • Molecular analysis of the methyl-prednisolone-mediated inhibition of NK-cell function: Evidence for different susceptibility of IL-2-versus IL-15-activated NK cells
    • Chiossone L, Vitale C, Cottalasso F, et al. Molecular analysis of the methyl-prednisolone-mediated inhibition of NK-cell function: evidence for different susceptibility of IL-2-versus IL-15-activated NK cells. Blood 2007; 109:3767-3775.
    • (2007) Blood , vol.109 , pp. 3767-3775
    • Chiossone, L.1    Vitale, C.2    Cottalasso, F.3
  • 21
    • 0034903681 scopus 로고    scopus 로고
    • Influence of long-term therapy with methotrexate and low dose corticosteroids on type 1 and type 2 cytokine production in CD4+ and CD8+ T lymphocytes of patients with rheumatoid arthritis
    • Schuerwegh AJ, van Offel JF, Bridts CH, et al. Influence of long-term therapy with methotrexate and low dose corticosteroids on type 1 and type 2 cytokine production in CD4+ and CD8+ T lymphocytes of patients with rheumatoid arthritis. J Rheumatol 2001; 28:1793-1799.
    • (2001) J Rheumatol , vol.28 , pp. 1793-1799
    • Schuerwegh, A.J.1    Van Offel, J.F.2    Bridts, C.H.3
  • 22
    • 0034653477 scopus 로고    scopus 로고
    • Cyclophosphamide induces type i interferon and augments the number of CD44(hi) T lymphocytes in mice: Implications for strategies of chemoimmunotherapy of cancer
    • Schiavoni G, Mattei F, Di Pucchio T, et al. Cyclophosphamide induces type I interferon and augments the number of CD44(hi) T lymphocytes in mice: implications for strategies of chemoimmunotherapy of cancer. Blood 2000; 95:2024-2030.
    • (2000) Blood , vol.95 , pp. 2024-2030
    • Schiavoni, G.1    Mattei, F.2    Di Pucchio, T.3
  • 23
    • 33847368549 scopus 로고    scopus 로고
    • Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
    • Ghiringhelli F, Menard C, Puig PE, et al. Metronomic cyclophosphamide regimen selectively depletes CD4+CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients. Cancer Immunol Immunother 2007; 56:641-648.
    • (2007) Cancer Immunol Immunother , vol.56 , pp. 641-648
    • Ghiringhelli, F.1    Menard, C.2    Puig, P.E.3
  • 24
    • 3042569675 scopus 로고    scopus 로고
    • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing
    • Chakraborty M, Abrams SI, Coleman CN, et al. External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine-mediated T-cell killing. Cancer Res 2004; 64:4328-4337.
    • (2004) Cancer Res , vol.64 , pp. 4328-4337
    • Chakraborty, M.1    Abrams, S.I.2    Coleman, C.N.3
  • 25
    • 2542421791 scopus 로고    scopus 로고
    • Cellular immunity in breast cancer patients completing taxane treatment
    • Carson WE 3rd, Shapiro CL, Crespin TR, et al. Cellular immunity in breast cancer patients completing taxane treatment. Clin Cancer Res 2004; 10:3401-3409.
    • (2004) Clin Cancer Res , vol.10 , pp. 3401-3409
    • Carson III, W.E.1    Shapiro, C.L.2    Crespin, T.R.3
  • 26
    • 0034796870 scopus 로고    scopus 로고
    • Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy
    • Demaria S, Volm MD, Shapiro RL, et al. Development of tumor-infiltrating lymphocytes in breast cancer after neoadjuvant paclitaxel chemotherapy. Clin Cancer Res 2001; 7:3025-3030.
    • (2001) Clin Cancer Res , vol.7 , pp. 3025-3030
    • Demaria, S.1    Volm, M.D.2    Shapiro, R.L.3
  • 27
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macro-phage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice
    • Machiels JP, Reilly RT, Emens LA, et al. Cyclophosphamide, doxorubicin, and paclitaxel enhance the antitumor immune response of granulocyte/macro-phage- colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerized mice. Cancer Res 2001; 61:3689-3697.
    • (2001) Cancer Res , vol.61 , pp. 3689-3697
    • MacHiels, J.P.1    Reilly, R.T.2    Emens, L.A.3
  • 28
    • 0037239826 scopus 로고    scopus 로고
    • Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer
    • Yu B, Kusmartsev S, Cheng F, et al. Effective combination of chemotherapy and dendritic cell administration for the treatment of advanced-stage experimental breast cancer. Clin Cancer Res 2003; 9:285-294.
    • (2003) Clin Cancer Res , vol.9 , pp. 285-294
    • Yu, B.1    Kusmartsev, S.2    Cheng, F.3
  • 29
    • 25144466458 scopus 로고    scopus 로고
    • Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity
    • Suzuki E, Kapoor V, Jassar AS, et al. Gemcitabine selectively eliminates splenic Gr-1+/CD11b+ myeloid suppressor cells in tumor-bearing animals and enhances antitumor immune activity. Clin Cancer Res 2005; 11:6713-6721.
    • (2005) Clin Cancer Res , vol.11 , pp. 6713-6721
    • Suzuki, E.1    Kapoor, V.2    Jassar, A.S.3
  • 30
    • 0037089545 scopus 로고    scopus 로고
    • Gemcitabine exerts a selective effect on the humoral immune response: Implications for combination chemo-immu-notherapy
    • Nowak AK, Robinson BW, Lake RA. Gemcitabine exerts a selective effect on the humoral immune response: implications for combination chemo-immu-notherapy. Cancer Res 2002; 62:2353-2358.
    • (2002) Cancer Res , vol.62 , pp. 2353-2358
    • Nowak, A.K.1    Robinson, B.W.2    Lake, R.A.3
  • 31
    • 1542719818 scopus 로고    scopus 로고
    • Drug-and cell-mediated antitumor cytotoxicities modulate cross-presentation of tumor antigens by myeloid dendritic cells
    • Galetto A, Buttiglieri S, Forno S, et al. Drug-and cell-mediated antitumor cytotoxicities modulate cross-presentation of tumor antigens by myeloid dendritic cells. Anticancer Drugs 2003; 14:833-843.
    • (2003) Anticancer Drugs , vol.14 , pp. 833-843
    • Galetto, A.1    Buttiglieri, S.2    Forno, S.3
  • 32
    • 0037457485 scopus 로고    scopus 로고
    • Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro
    • Correale P, Aquino A, Giuliani A, et al. Treatment of colon and breast carcinoma cells with 5-fluorouracil enhances expression of carcinoembryonic antigen and susceptibility to HLA-A(*)02.01 restricted, CEA-peptide-specific cytotoxic T cells in vitro. Int J Cancer 2003; 104:437-445.
    • (2003) Int J Cancer , vol.104 , pp. 437-445
    • Correale, P.1    Aquino, A.2    Giuliani, A.3
  • 33
    • 70350569295 scopus 로고    scopus 로고
    • Activation of the NLRP3 inflamma-some in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors
    • Ghiringhelli F, Apetoh L, Tesniere A, et al. Activation of the NLRP3 inflamma-some in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors. Nat Med 2009; 15:1170-1178.
    • (2009) Nat Med , vol.15 , pp. 1170-1178
    • Ghiringhelli, F.1    Apetoh, L.2    Tesniere, A.3
  • 34
    • 8844232668 scopus 로고    scopus 로고
    • P2X7 receptor polymorphism impairs extracellular adenosine 5'-triphosphate-induced interleukin-18 release from human monocytes
    • Sluyter R, Dalitz JG, Wiley JS. P2X7 receptor polymorphism impairs extracellular adenosine 5'-triphosphate-induced interleukin-18 release from human monocytes. Genes Immun 2004; 5:588-591.
    • (2004) Genes Immun , vol.5 , pp. 588-591
    • Sluyter, R.1    Dalitz, J.G.2    Wiley, J.S.3
  • 35
    • 77951058617 scopus 로고    scopus 로고
    • Trastuzumab-based therapy for patients with HER2-positive breast cancer: From early scientific development to foundation of care
    • Brufsky A. Trastuzumab-based therapy for patients with HER2-positive breast cancer: from early scientific development to foundation of care. Am J Clin Oncol; 33:186-195.
    • Am J Clin Oncol , vol.33 , pp. 186-195
    • Brufsky, A.1
  • 36
    • 66249091930 scopus 로고    scopus 로고
    • The HER-2 receptor and breast cancer: Ten years of targeted anti-HER-2 therapy and personalized medicine
    • Ross JS, Slodkowska EA, Symmans WF, et al. The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. Oncologist 2009; 14:320-368.
    • (2009) Oncologist , vol.14 , pp. 320-368
    • Ross, J.S.1    Slodkowska, E.A.2    Symmans, W.F.3
  • 37
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • Musolino A, Naldi N, Bortesi B, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol 2008; 26:1789-1796.
    • (2008) J Clin Oncol , vol.26 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    Bortesi, B.3
  • 38
    • 79957874790 scopus 로고    scopus 로고
    • Fc{gamma}R2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer
    • Tamura K, Shimizu C, Hojo T, et al. Fc{gamma}R2A and 3A polymorphisms predict clinical outcome of trastuzumab in both neoadjuvant and metastatic settings in patients with HER2-positive breast cancer. Ann Oncol 2011; 22:1302-1307.
    • (2011) Ann Oncol , vol.22 , pp. 1302-1307
    • Tamura, K.1    Shimizu, C.2    Hojo, T.3
  • 39
    • 79955570584 scopus 로고    scopus 로고
    • Anti-ErbB-2 mAb therapy requires type Iand II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy
    • Stagg J, Loi S, Divisekera U, et al. Anti-ErbB-2 mAb therapy requires type Iand II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapy. Proc Natl Acad Sci USA 2011; 108:7142-7147.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 7142-7147
    • Stagg, J.1    Loi, S.2    Divisekera, U.3
  • 40
    • 77955534002 scopus 로고    scopus 로고
    • The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity
    • Park S, Jiang Z, Mortenson ED, et al. The therapeutic effect of anti-HER2/neu antibody depends on both innate and adaptive immunity. Cancer Cell 2010; 18:160-170.
    • (2010) Cancer Cell , vol.18 , pp. 160-170
    • Park, S.1    Jiang, Z.2    Mortenson, E.D.3
  • 41
    • 78649993460 scopus 로고    scopus 로고
    • CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation
    • Rakhra K, Bachireddy P, Zabuawala T, et al. CD4(+) T cells contribute to the remodeling of the microenvironment required for sustained tumor regression upon oncogene inactivation. Cancer Cell 2010; 18:485-498.
    • (2010) Cancer Cell , vol.18 , pp. 485-498
    • Rakhra, K.1    Bachireddy, P.2    Zabuawala, T.3
  • 42
    • 77954899030 scopus 로고    scopus 로고
    • Phase i study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
    • Brahmer JR, Drake CG, Wollner I, et al. Phase I study of single-agent antiprogrammed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010; 28:3167-3175.
    • (2010) J Clin Oncol , vol.28 , pp. 3167-3175
    • Brahmer, J.R.1    Drake, C.G.2    Wollner, I.3
  • 43
    • 77954801079 scopus 로고    scopus 로고
    • Improved survival with ipilimumab in patients with metastatic melanoma
    • Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363:711-723.
    • (2010) N Engl J Med , vol.363 , pp. 711-723
    • Hodi, F.S.1    O'Day, S.J.2    McDermott, D.F.3
  • 44
    • 79960303412 scopus 로고    scopus 로고
    • Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models
    • Persson J, Beyer I, Yumul R, et al. Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models. PloS One 2011; 6:e22303.
    • (2011) PloS One , vol.6
    • Persson, J.1    Beyer, I.2    Yumul, R.3
  • 45
    • 84875722651 scopus 로고    scopus 로고
    • Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancertrial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98
    • Loi S, Sirtaine N, Piette F, et al. Prognostic and predictive value of tumor-infiltrating lymphocytes in a phase III randomized adjuvant breast cancertrial in node-positive breast cancer comparing the addition of docetaxel to doxorubicin with doxorubicin-based chemotherapy: BIG 02-98. J Clin Oncol 2013; 31:860-867.
    • (2013) J Clin Oncol , vol.31 , pp. 860-867
    • Loi, S.1    Sirtaine, N.2    Piette, F.3
  • 46
    • 33846935228 scopus 로고    scopus 로고
    • Unique human tumor antigens: Immunobiology and use in clinical trials
    • Parmiani G, De Filippo A, Novellino L, Castelli C. Unique human tumor antigens: immunobiology and use in clinical trials. J Immunol 2007; 178:1975-1979.
    • (2007) J Immunol , vol.178 , pp. 1975-1979
    • Parmiani, G.1    De Filippo, A.2    Novellino, L.3    Castelli, C.4
  • 47
    • 35348841582 scopus 로고    scopus 로고
    • Universal and stemness-related tumor antigens: Potential use in cancer immunotherapy
    • Parmiani G, Russo V, Marrari A, et al. Universal and stemness-related tumor antigens: potential use in cancer immunotherapy. Clin Cancer Res 2007; 13:5675-5679.
    • (2007) Clin Cancer Res , vol.13 , pp. 5675-5679
    • Parmiani, G.1    Russo, V.2    Marrari, A.3
  • 48
    • 71749104702 scopus 로고    scopus 로고
    • Immunizing against breast cancer: A new swing for an old sword
    • Curigliano G, Locatelli M, Fumagalli L, Goldhirsch A. Immunizing against breast cancer: a new swing for an old sword. Breast 2009; 18 (Suppl 3):S51-S54.
    • (2009) Breast , vol.18 , Issue.SUPPL. 3
    • Curigliano, G.1    Locatelli, M.2    Fumagalli, L.3    Goldhirsch, A.4
  • 49
    • 0037444166 scopus 로고    scopus 로고
    • Development and preclinical evaluation of a Bacillus Calmette-Guerin- MUC1-based novel breast cancer vaccine
    • Chung MA, Luo Y, O'Donnell M, et al. Development and preclinical evaluation of a Bacillus Calmette-Guerin-MUC1-based novel breast cancer vaccine. Cancer Res 2003; 63:1280-1287.
    • (2003) Cancer Res , vol.63 , pp. 1280-1287
    • Chung, M.A.1    Luo, Y.2    O'Donnell, M.3
  • 50
    • 3042745485 scopus 로고    scopus 로고
    • Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein-based vaccine
    • Disis ML, Schiffman K, Guthrie K, et al. Effect of dose on immune response in patients vaccinated with an her-2/neu intracellular domain protein-based vaccine. J Clin Oncol 2004; 22:1916-1925.
    • (2004) J Clin Oncol , vol.22 , pp. 1916-1925
    • Disis, M.L.1    Schiffman, K.2    Guthrie, K.3
  • 51
    • 0029949563 scopus 로고    scopus 로고
    • Carcinoembryonic antigen as a target for cancer vaccines
    • Hodge JW. Carcinoembryonic antigen as a target for cancer vaccines. Cancer Immunol Immunother 1996; 43:127-134.
    • (1996) Cancer Immunol Immunother , vol.43 , pp. 127-134
    • Hodge, J.W.1
  • 52
    • 0031041774 scopus 로고    scopus 로고
    • Analysis of telomerase activity levels in breast cancer: Positive detection at the in situ breast carcinoma stage
    • Bednarek AK, Sahin A, Brenner AJ, et al. Analysis of telomerase activity levels in breast cancer: positive detection at the in situ breast carcinoma stage. Clin Cancer Res 1997; 3:11-16.
    • (1997) Clin Cancer Res , vol.3 , pp. 11-16
    • Bednarek, A.K.1    Sahin, A.2    Brenner, A.J.3
  • 53
    • 36549023384 scopus 로고    scopus 로고
    • WT1-specific T cell receptor gene therapy: Improving TCR function in transduced T cells
    • Stauss HJ, Thomas S, Cesco-Gaspere M, et al. WT1-specific T cell receptor gene therapy: improving TCR function in transduced T cells. Blood Cells Mol Dis 2008; 40:113-116.
    • (2008) Blood Cells Mol Dis , vol.40 , pp. 113-116
    • Stauss, H.J.1    Thomas, S.2    Cesco-Gaspere, M.3
  • 54
    • 20944442315 scopus 로고    scopus 로고
    • Escape strategies and reasons for failure in the interaction between tumour cells and the immune system: How can we tilt the balance towards immune-mediated cancer control?
    • Rivoltini L, Canese P, Huber V, et al. Escape strategies and reasons for failure in the interaction between tumour cells and the immune system: how can we tilt the balance towards immune-mediated cancer control? Expert Opin Biol Ther 2005; 5:463-476.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. 463-476
    • Rivoltini, L.1    Canese, P.2    Huber, V.3
  • 55
    • 0030000007 scopus 로고    scopus 로고
    • A phase i trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma
    • Goydos JS, Elder E, Whiteside TL, et al. A phase I trial of a synthetic mucin peptide vaccine. Induction of specific immune reactivity in patients with adenocarcinoma. J Surg Res 1996; 63:298-304.
    • (1996) J Surg Res , vol.63 , pp. 298-304
    • Goydos, J.S.1    Elder, E.2    Whiteside, T.L.3
  • 56
    • 0035113705 scopus 로고    scopus 로고
    • Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients
    • Knutson KL, Schiffman K, Disis ML. Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients. J Clin Investig 2001; 107:477-484.
    • (2001) J Clin Investig , vol.107 , pp. 477-484
    • Knutson, K.L.1    Schiffman, K.2    Disis, M.L.3
  • 57
    • 0029787977 scopus 로고    scopus 로고
    • Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamide
    • MacLean GD, Miles DW, Rubens RD, et al. Enhancing the effect of THERATOPE STn-KLH cancer vaccine in patients with metastatic breast cancer by pretreatment with low-dose intravenous cyclophosphamide. J Immunother Emphasis Tumor Immunol 1996; 19:309-316.
    • (1996) J Immunother Emphasis Tumor Immunol , vol.19 , pp. 309-316
    • MacLean, G.D.1    Miles, D.W.2    Rubens, R.D.3
  • 58
    • 0034551730 scopus 로고    scopus 로고
    • Phase i study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anticarcinoembryonic antigen immune responses
    • Marshall JL, Hoyer RJ, Toomey MA, et al. Phase I study in advanced cancer patients of a diversified prime-and-boost vaccination protocol using recombinant vaccinia virus and recombinant nonreplicating avipox virus to elicit anticarcinoembryonic antigen immune responses. J Clin Oncol 2000; 18:3964-3973.
    • (2000) J Clin Oncol , vol.18 , pp. 3964-3973
    • Marshall, J.L.1    Hoyer, R.J.2    Toomey, M.A.3
  • 59
    • 24944478531 scopus 로고    scopus 로고
    • Leveraging the activity of tumor vaccines with cytotoxic chemotherapy
    • Emens LA, Jaffee EM. Leveraging the activity of tumor vaccines with cytotoxic chemotherapy. Cancer Res 2005; 65:8059-8064.
    • (2005) Cancer Res , vol.65 , pp. 8059-8064
    • Emens, L.A.1    Jaffee, E.M.2
  • 60
    • 38449116825 scopus 로고    scopus 로고
    • Chemotherapy and tumor immunity: An unexpected collaboration
    • Emens LA. Chemotherapy and tumor immunity: an unexpected collaboration. Front Biosci 2008; 13:249-257.
    • (2008) Front Biosci , vol.13 , pp. 249-257
    • Emens, L.A.1
  • 61
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • Finn OJ. Cancer immunology. N Engl J Med 2008; 358:2704-2715.
    • (2008) N Engl J Med , vol.358 , pp. 2704-2715
    • Finn, O.J.1
  • 62
    • 33845993628 scopus 로고    scopus 로고
    • A clinical development paradigm for cancer vaccines and related biologics
    • Hoos A, Parmiani G, Hege K, et al. A clinical development paradigm for cancer vaccines and related biologics. J Immunother 2007; 30: 1-15.
    • (2007) J Immunother , vol.30 , pp. 1-15
    • Hoos, A.1    Parmiani, G.2    Hege, K.3
  • 63
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • Kantoff PW, Higano CS, Shore ND, et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 2010; 363:411-422.
    • (2010) N Engl J Med , vol.363 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 64
    • 77249089345 scopus 로고    scopus 로고
    • MAGRIT: The largest-ever phase III lung cancer trial aims to establish a novel tumor-specific approach to therapy
    • Tyagi P, Mirakhur B. MAGRIT: the largest-ever phase III lung cancer trial aims to establish a novel tumor-specific approach to therapy. Clin Lung Cancer 2009; 10:371-374.
    • (2009) Clin Lung Cancer , vol.10 , pp. 371-374
    • Tyagi, P.1    Mirakhur, B.2
  • 65
    • 79957831345 scopus 로고    scopus 로고
    • Gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
    • Schwartzentruber DJ, Lawson DH, Richards JM, et al. gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med; 364:2119-2127.
    • N Engl J Med , vol.364 , pp. 2119-2127
    • Schwartzentruber, D.J.1    Lawson, D.H.2    Richards, J.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.