Review of membranes in microfluidics

Journal of Chemical Technology and Biotechnology

Volumn 92, Issue 2, 2017, Pages 271-282

  Chen, Xueye ^a   Shen, Jienan ^a  

^a LIAONING UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

applications; manufacturing methods; mass transfer; membranes; microfluidics

Indexed keywords

APPLICATIONS; CHEMICAL DETECTION; MANUFACTURE; MASS TRANSFER; MEMBRANES; TRANSPORT PROPERTIES;

BASIC CONCEPTS; CHEMICAL REAGENTS; DRUG SCREENING; FLUID TRANSPORT; GAS DETECTION; MANUFACTURING METHODS; MICRO REACTOR; MICRO-FLUIDIC DEVICES;

MICROFLUIDICS;

PROTEIN; REAGENT;

BIOREACTOR; CELLS; CHEMICAL ANALYSIS; DRUG RESEARCH; DRUG SCREENING; ELECTRIC FIELD; FLUID TRANSPORT; GAS ANALYSIS; MEDICAL RESEARCH; MEMBRANE TECHNOLOGY; MICROFLUIDICS; MICROREACTOR; MICROTECHNOLOGY; PUMP; REVIEW; THEORETICAL STUDY;

EID: 84991694225     PISSN: 02682575     EISSN: 10974660     Source Type: Journal    
DOI: 10.1002/jctb.5105     Document Type: Review

References (155)

1. Karimi A, Karig D, Kumar A and Ardekani AM. Interplay of physical mechanisms and biofilm processes: review of microfluidic methods. J Lab on a Chip 15:23–42 (2015).
2. Bokharaei M, Schneider T, Dutz S, Stone RC, Mefford OT and Häfeli UO, Production of monodispersed magnetic polymeric microspheres in a microfluidic chip and 3D simulation. J Microfluidics Nanofluidics 20:1–14 (2016).
3. Lee JY, Tan WS, An J, Chua CK, Tang CY, Fane AG et al., The potential to enhance membrane module design with 3D printing technology. J Membrane Sci 499:480–490 (2016).
4. Kosinov N, Gascon J, Kapteijn F and Hensen EJM, Recent developments in zeolite membranes for gas separation. J Membrane Sci 499:65–79 (2016).
5. Chekli L, Phuntsho S, Kim JE, Kim J, Choi JY, Choi JS et al., A comprehensive review of hybrid forward osmosis systems: performance, applications and future prospects. J Membrane Sci 497:430–449 (2016).
6. Kim J and Gale BK, Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlO x membrane. J Lab on a Chip 8:1516–1523 (2008).
7. Sheng Y and Bowser MT, Size selective DNA transport through a nanoporous membrane in a PDMS microfluidic device. J Analyst 137:1144–1151 (2012).
8. Sticker D, Rothbauer M, Lechner S, Hehenberger MT and Ertl P, Multi-layered, membrane-integrated microfluidics based on replica molding of a thiol–ene epoxy thermoset for organ-on-a-chip applications. J Lab on a Chip 15:4542–4554 (2015).
9. Gel M, Kandasamy S, Cartledge K, Be CL and Haylock D, Micro pore arrays in free standing cyclic olefin copolymer membranes: fabrication and surface functionalization strategies for in vitro barrier tissue models C//SPIE Micro + Nano Materials, Devices, and Applications. Int Soc Optics Photon: 89233E–89233E-6 (2013).
10. Zeitoun RI, Goudie MJ, Zwier J, Mahawillia D and Burns MA, Active control of nanolitre droplet contents with convective concentration gradients across permeable walls. J Lab on a Chip 11:4022–4028 (2011).
11. Vladisavljević GT, Kobayashi I and Nakajima M, Production of uniform droplets using membrane, microchannel and microfluidic emulsification devices. J Microfluid nanofluid 13:151–178 (2012).
12. Neeves KB and Diamond SL, A membrane-based microfluidic device for controlling the flux of platelet agonists into flowing blood. J Lab on a Chip 8:701–709 (2008).
13. Thorslund S, Klett O, Nikolajeff F, Markides K and Bergquist J, A hybrid poly (dimethylsiloxane) microsystem for on-chip whole blood filtration optimized for steroid screening. J Biomed Microdevices 8:73–79 (2006).
14. Moskvin LN and Nikitina TG, Membrane methods of substance separation in analytical chemistry. J Anal Chem 59:2–16 (2004).
15. Cheng S, Oatley DL, Williams PM and Wright CJ, Positively charged nanofiltration membranes: review of current fabrication methods and introduction of a novel approach. J Adv Colloid Interface Sci 164:12–20 (2011).
16. Shen Y, Saboe PO, Sines IT, Erbakan M and Kumar M, Biomimetic membranes: a review. J Membrane Sci 454:359–381 (2014).
17. Jin J, Walczak K, Singh MR, Karp C, Lewis NS and Xiang C, An experimental and modeling/simulation-based evaluation of the efficiency and operational performance characteristics of an integrated, membrane-free, neutral pH solar-driven water-splitting system. J Energy Environ Sci 7:3371–3380 (2014).
18. 2 separation. J Membr Sci 497:1–20 (2016).
19. De Jong J, Lammertink RGH and Wessling M, Membranes and microfluidics: a review. J Lab on a Chip 6:1125–1139 (2006).
20. Guo DJ, Xiao SJ, Liu HB, Chao J, Xia B, Wang J et al., Diffusion of hydrosilanes from the control layer to the vinylsilane-rich flow membrane during the fabrication of microfluidic chips. J Langmuir 21:10487–10491 (2005).
21. Luo X, Wu HC, Betz J, Rubloffd GW and Bentley WE, Air bubble-initiated biofabrication of freestanding, semi-permeable biopolymer membranes in PDMS microfluidics. J Biochem Eng J 89:2–9 (2014).
22. Ota S, Suzuki H and Takeuchi S, Microfluidic lipid membrane formation on microchamber arrays. J Lab on a Chip 11:2485–2487 (2011).
23. Kang JH, Um E and Park JK, Fabrication of a poly (dimethylsiloxane) membrane with well-defined through-holes for three-dimensional microfluidic networks. J Micromechan Microeng 19:045027 (2009).
24. Lu Y, Shi W, Qin J and Lin B, Fabrication and characterization of paper-based microfluidics prepared in nitrocellulose membrane by wax printing. J Anal Chem 82:329–335 (2009).
25. Luo Y and Zare RN, Perforated membrane method for fabricating three-dimensional polydimethylsiloxane microfluidic devices. J Lab on a Chip 8:1688–1694 (2008).
26. Femmer T, Kuehne AJC, Torres-Rendon J, Walther A and Wessling M, Print your membrane: rapid prototyping of complex 3D-PDMS membranes via a sacrificial resist. J Membr Sci 478:12–18 (2015).
27. Cacho-Bailo F, Catalán-Aguirre S, Etxeberría-Benavides M, Karvan O, Sebastian V, Téllez C et al., Metal-organic framework membranes on the inner-side of a polymeric hollow fiber by microfluidic synthesis. J Membr Sci 476:277–285 (2015).
28. Lamberti A, Marasso SL and Cocuzza M, PDMS membranes with tunable gas permeability for microfluidic applications. J RSC Adv 4:61415–61419 (2014).
29. Lu JC, Liao WH and Tung YC, Magnet-assisted device-level alignment for the fabrication of membrane-sandwiched polydimethylsiloxane microfluidic devices. J Micromechan Microeng 22:075006 (2012).
30. Nichols KP, Eijkel JCT and Gardeniers HJGE, Nanochannels in SU-8 with floor and ceiling metal electrodes and integrated microchannels. J Lab on a Chip 8:173–175 (2008).
31. Slouka Z, Senapati S and Chang HC, Microfluidic systems with ion-selective membranes. J Ann Rev Anal Chem 7:317–335 (2014).
32. Lefebvre Y, Leclerc E and Barthès-Biesel D, et al., Flow of artificial microcapsules in microfluidic channels: a method for determining the elastic properties of the membrane. J Phys Fluids (1994-present) 20:123102 (2008).
33. Wardrip NC and Arnusch CJ, Three-dimensionally printed microfluidic cross-flow system for ultrafiltration/nanofiltration membrane performance testing. J JoVE (Journal of Visualized Experiments) 108:e53556–e53556 (2016).
34. Warkiani ME, Wicaksana F, Fane AG and Gong HQ, Investigation of membrane fouling at the microscale using isopore filters. J Microfluid Nanofluid 19:307–315 (2015).
35. Zhan X, Li J, Huang J and Chen C, Enhanced pervaporation performance of multi-layer PDMS/PVDF composite membrane for ethanol recovery from aqueous solution. J Appl Biochem Biotechnol 160:632–642 (2010).
36. Chovau S, Dobrak A, Figoli A, Galiano F, Simone S, Drioli E et al., Pervaporation performance of unfilled and filled PDMS membranes and novel SBS membranes for the removal of toluene from diluted aqueous solutions. Chem Eng J 159:37–46 (2010).
37. Zhan X, Fan C and Han X, Pervaporation separation of ethanol/water mixtures with chlorosilane modified silicalite-1/PDMS hybrid membranes. Chinese J Polym Sci 28:625–635 (2010).
38. Li SY, Srivastava R and Parnas RS, Separation of 1-butanol by pervaporation using a novel tri-layer PDMS composite membrane. J Membrane Sci 363:287–294 (2010).
39. Sadrzadeh M, Saljoughi E, Shahidi K and Mohammadi T, Preparation and characterization of a composite PDMS membrane on CA support. J Polym Adv Technol 21:568–577 (2010).
40. Dobrak A, Figoli A, Chovau S, Galiano F, Simone S, Vankelecom IF et al., Performance of PDMS membranes in pervaporation: effect of silicalite fillers and comparison with SBS membranes. J Colloid Interface Sci 346:254–264 (2010).
41. Liu G, Wei W, Wu H, Dong X, Jiang M and Jin W, Pervaporation performance of PDMS/ceramic composite membrane in acetone butanol ethanol (ABE) fermentation – PV coupled process. J Membr Sci 373:121–129 (2011).
42. Yi S, Su Y and Wan Y, Preparation and characterization of vinyltriethoxysilane (VTES) modified silicalite-1/PDMS hybrid pervaporation membrane and its application in ethanol separation from dilute aqueous solution. J Membr Sci 360:341351 (2010).
43. Brask A, Kutter JP and Bruus H, Long-term stable electroosmotic pump with ion exchange membranes. J Lab on a Chip 5:730–738 (2005).
44. Hisamoto H, Shimizu Y, Uchiyama K, Tokeshi M, Kikutani Y, Hibara A et al., Chemicofunctional membrane for integrated chemical processes on a microchip. J Anal Chem 75:350–354 (2003).
45. Aran K, Sasso LA, Kamdar N and Zahn JD, Irreversible, direct bonding of nanoporous polymer membranes to PDMS or glass microdevices. J Lab on a Chip 10:548–552 (2010).
46. Sundararajan N, Kim D and Berlin AA, Microfluidic operations using deformable polymer membranes fabricated by single layer soft lithography. J Lab on a Chip 5:350–354 (2005).
47. Kelly RT, Li Y and Woolley AT, Phase-changing sacrificial materials for interfacing microfluidics with ion-permeable membranes to create on-chip preconcentrators and electric field gradient focusing microchips. J Anal Chem 78:2565–2570 (2006).
48. Russo AP, Retterer ST, Spence AJ, Isaacson MS, Lepak LA, Spencer MG et al., Direct casting of polymer membranes into microfluidic devices. J Sep Sci Technol 39:2515–2530 (2004).
49. Zheng Y, Shojaei-Baghini E, Wang C and Sun Y, Microfluidic characterization of specific membrane capacitance and cytoplasm conductivity of singlecells. J Biosens Bioelectron 42:496–502 (2013).
50. Chen MB, Srigunapalan S, Wheeler AR and Simmons CA, A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell–cell interactions. J Lab on a Chip 13:2591–2598 (2013).
51. Evenou F, Couderc S, Kim B, Fujii T and Sakai Y, Microfibrillated cellulose sheets coating oxygen-permeable PDMS membranes induce rat hepatocytes 3D aggregation into stably-attached 3D hemispheroids. J Biomater Sci Polym Edn 22:1509–1522 (2011).
52. Wei H, Chueh B, Wu H, Hall EW, Li CW, Schirhagl R et al., Particle sorting using a porous membrane in a microfluidic device. J Lab on a Chip 11:238–245 (2011).
53. Inamdar NK, Griffith LG and Borenstein JT, Transport and shear in a microfluidic membrane bilayer device for cell culture. J Biomicrofluidics 5:022213 (2011).
54. Srigunapalan S, Lam C, Wheeler AR, and Simmons CA, A microfluidic membrane device to mimic critical components of the vascular microenvironment. J Biomicrofluidics 5:013409 (2011).
55. Liu ZB, Zhang Y, Yu JJ, Maka AFT, Lib Y and Yang M, A microfluidic chip with poly (ethylene glycol) hydrogel microarray on nanoporous alumina membrane for cell patterning and drug testing. J Sensors Actuators B: Chem 143:776–783 (2010).
56. Evenou F, Fujii T and Sakai Y, Spontaneous formation of stably-attached and 3D-organized hepatocyte aggregates on oxygen-permeable polydimethylsiloxane membranes having 3D microstructures. J Biomed Microdevices 12:465–475 (2010).
57. Young EWK, Watson MWL, Srigunapalan S, Wheeler AR and Simmons CA, Technique for real-time measurements of endothelial permeability in a microfluidic membrane chip using laser-induced fluorescence detection. J Anal Chem 82:808–816 (2010).
58. Dharmasiri U, Balamurugan S, Adams AA, Okagbare PI, Obubuafo A and Soper SA, Highly efficient capture and enumeration of low abundance prostate cancer cells using prostate–specific membrane antigen aptamers immobilized to a polymeric microfluidic device. J Electrophoresis 30:3289–3300 (2009).
59. Jensen KH, Lee J, Bohr T and Bruus H, Osmotically driven flows in microchannels separated by a semipermeable membrane. J Lab on a Chip 9:2093–2099 (2009).
60. Zhang J, Yan S, Yuan D, Alici G, Nguyen N and Li W, High Throughput cell-free extraction of plasma by an integrated microfluidic device combining inertial microfluidics and membrane. C//ASME 2016 5th International Conference on Micro/Nanoscale Heat and Mass Transfer. American Society of Mechanical Engineers 2016: V001T01A012-V001T01A012.
61. Ravetto A, Hoefer IE, den Toonder JMJ and Bouten CV, A membrane-based microfluidic device for mechano-chemical cell manipulation. J Biomed Microdevices 18:1–11 (2016).
62. Fan X, Jia C, Yang J, Lia G, Mao H, Jina Q et al., A microfluidic chip integrated with a high-density PDMS-based microfiltration membrane for rapid isolation and detection of circulating tumor cells. J Biosensors Bioelectron 71:380–386 (2015).
63. Zhao Y, Chen D, Luo Y, Chen F, Zhao X, Jiang M et al., Simultaneous characterization of instantaneous Young's modulus and specific membrane capacitance of single cells using a microfluidic system. J Sensors 15:2763–2773 (2015).
64. Huang SB, Zhao Y, Chen D, Lee HC, Luo Y, Chiu TK et al., A clogging-free microfluidic platform with an incorporated pneumatically driven membrane-based active valve enabling specific membrane capacitance and cytoplasm conductivity characterization of single cells. J Sensors Actuators B: Chem 190:928–936 (2014).
65. Zhao Y, Chen D, Li H, Luo Y, Deng B, Huang SB et al., A microfluidic system enabling continuous characterization of specific membrane capacitance and cytoplasm conductivity of single cells in suspension. J Biosens Bioelectron 43:304–307 (2013).
66. Tan Q, Ferrier GA, Chen BK, Wang C and Sun Y, Quantification of the specific membrane capacitance of single cells using a microfluidic device and impedance spectroscopy measurement. J Biomicrofluidics 6:034112 (2012).
67. Hediger S, Fontannaz J, Sayah A, Hunziker W and Gijs MAM, Biosystem for the culture and characterisation of epithelial cell tissues. J Sensors Actuators B: Chem 63:63–73 (2000).
68. Hediger S, Sayah A, Horisberger JD and Gijs MAM, Modular microsystem for epithelial cell culture and electrical characterization. J Biosensors Bioelectron 16:689–694 (2001).
69. Ostrovidov S, Jiang J, Sakai Y and Fujii T, Membrane-based PDMS microbioreactor for perfused 3D primary rat hepatocyte cultures. J Biomed Microdevices 6:279–287 (2004).
70. Dharmasiri U, Balamurugan S, Adams AA, Okagbare PI, Obubuafo A and Soper SA, Highly efficient capture and enumeration of low abundance prostate cancer cells using prostate-specific membrane antigen aptamers immobilized to a polymeric microfluidic device. J Electrophoresis 30:3289–3300 (2009).
71. Chen MB, Srigunapalan S, Wheeler AR and Simmons CA, A 3D microfluidic platform incorporating methacrylated gelatin hydrogels to study physiological cardiovascular cell–cell interactions. J Lab on a Chip 13:2591–2598 (2013).
72. Fan X, Jia C, Yang J, Li G, Mao H, Jin Q et al., A microfluidic chip integrated with a high-density PDMS-based microfiltration membrane for rapid isolation and detection of circulating tumor cells. J Biosensors Bioelectron 71:380–386 (2015).
73. Abate AR, Agresti JJ and Weitz DA, Microfluidic sorting with high-speed single-layer membrane valves. J Appl Phys Lett 96:203509 (2010).
74. Li L, Wang Q, Feng J, Tong L and Tang B, Highly sensitive and homogeneous detection of membrane protein on a single living cell by aptamer and nicking enzyme assisted signal amplification based on microfluidic droplets. J Analyt Chem 86:5101–5107 (2014).
75. Kreutz JE, Li L, Roach LS, Hatakeyama T and Ismagilov RF, Laterally mobile, functionalized self-assembled monolayers at the fluorous − aqueous interface in a plug-based microfluidic system: characterization and testing with membrane protein crystallization. J Am Chem Soc 131:6042–6043 (2009).
76. Funakoshi K, Suzuki H and Takeuchi S, Lipid bilayer formation by contacting monolayers in a microfluidic device for membrane protein analysis. J Anal Chem 78:8169–8174 (2006).
77. Khvostichenko DS, Schieferstein JM, Pawate AS, Laible PD and Kenis PJA, X-ray transparent microfluidic chip for mesophase-based crystallization of membrane proteins and on-chip structure determination. J Crystal Growth Design 14:4886–4890 (2014).
78. Hutter I, Müller E, Kristiansen PM, Kresak S and Tiefenauer L, Polymer-based microfluidic device for measuring membrane protein activities. J Microfluidics Nanofluidics 14:421–429 (2013).
79. Suzuki H, Tabata KV, Noji H, and Takeuchi S, Highly reproducible method of planar lipid bilayer reconstitution in polymethyl methacrylate microfluidic chip. J Langmuir 22:1937–1942 (2006).
80. Zagnoni M, Sandison ME and Morgan H, Microfluidic array platform for simultaneous lipid bilayer membrane formation. J Biosensors Bioelectron 24:1235–1240 (2009).
81. Garcia-Cordero JL and Maerkl SJ, Multiplexed surface micropatterning of proteins with a pressure-modulated microfluidic button-membrane. J Chem Commun 49:1264–1266 (2013).
82. Gao J, Xu J, Locascio LE and Lee CS, Integrated microfluidic system enabling protein digestion, peptide separation, and protein identification. J Anal Chem 73:2648–2655 (2001).
83. Lion N, Gellon JO, Jensen H and Girault HH, On-chip protein sample desalting and preparation for direct coupling with electrospray ionization mass spectrometry. J Chromatog A 1003:11–19 (2003).
84. Cooper JW, Chen J, Li Y and Lee CS, Membrane-based nanoscale proteolytic reactor enabling protein digestion, peptide separation, and protein identification using mass spectrometry. J Anal Chem 75:1067–1074 (2003).
85. Astorga-Wells J, Jörnvall H and Bergman T, A microfluidic electrocapture device in sample preparation for protein analysis by MALDI mass spectrometry. J Analyt Chem 75:5213–5219 (2003).
86. Song S, Singh AK, Shepodd TJ and Kirby BJ, Microchip dialysis of proteins using in situ photopatterned nanoporous polymer membranes. J Anal Chem 76:2367–2373 (2004).
87. Foote RS, Khandurina J, Jacobson SC and Ramsey JM, Preconcentration of proteins on microfluidic devices using porous silica membranes. J Anal Chem 77:57–63 (2005).
88. Pereira-Medrano AG, Forster S, Fowler GJS, McArthur SL and Wright PC, Rapid fabrication of glass/PDMS hybrid µIMER for high throughput membrane proteomics. J Lab on a Chip 10:3397–3406 (2010).
89. Kim JE, Cho JH and Paek SH, Functional membrane-implanted lab-on-a-chip for analysis of percent HDL cholesterol. J Anal Chem 77:7901–7907 (2005).
90. Hu R, Feng X, Chen P, Fu M, Chen H, Guo L et al., Rapid, highly efficient extraction and purification of membrane proteins using a microfluidic continuous-flow based aqueous two-phase system. J Chromatog A 1218:171–177 (2011).
91. Ikuta K, Maruo S, Fujisawa T and Yamada A, Micro concentrator with opto-sense micro reactor for biochemical IC chip family. 3D composite structure and experimental verification. 12th IEEE International Conference on Micro Electro Mechanical Systems, 1999. MEMS'99. IEEE, 1999:376–381.
92. Jiang Y and Lee CS, On-line coupling of micro-enzyme reactor with micro-membrane chromatography for protein digestion, peptide separation, and protein identification using electrospray ionization mass spectrometry. J Chromatog A 924:315–322 (2001).
93. Wan YSS, Chau JLH, Gavriilidis A and Yeung KL, Design and fabrication of zeolite-based microreactors and membrane microseparators. J Micropor Mesopor Mater 42:157–175 (2001).
94. Chau JLH, Wan YSS, Gavriilidis A and Yeung KL, Incorporating zeolites in microchemical systems. J Chem Eng 88:187–200 (2002).
95. Karnik SV, Hatalis MK and Kothare MV, Towards a palladium micro-membrane for the water gas shift reaction: microfabrication approach and hydrogen purification results. J Microelectromechan Syst 12:93–100 (2003).
96. Lai SM, Ng CP, Martin-Aranda R and Yeung KL, Knoevenagel condensation reaction in zeolite membrane microreactor. J Micropor Mesopor Mater 66:239–252 (2003).
97. Schuster A, Lakshmanan R, Ponton J and Sefiane K, Modelling a novel miniaturised reactor/separator system. J Chem Technol Biotechnol 78:342–346 (2003).
98. Zanzotto A, Szita N, Boccazzi P, Lessard P, Sinskey AJ and Jensen KF, Membrane–aerated microbioreactor for high–throughput bioprocessing. J Biotechnol Bioeng 87:243–254 (2004).
99. Yeung KL, Zhang X, Lau WN, and Martin-Aranda R, Experiments and modeling of membrane microreactors. J Catal Today 110:26–37 (2005).
100. Li J, Zhang M, Wang L, Li W, Sheng P and Wen W, Design and fabrication of microfluidic mixer from carbonyl iron–PDMS composite membrane. J Microfluidics Nanofluidics 10:919–925 (2011).
101. Brown AJ, Brunelli NA, Eum K, Rashidi F, Johnson JR, Koros WJ et al., Interfacial microfluidic processing of metal-organic framework hollow fiber membranes. J Sci 2014, 345:72–75 (2014).
102. Xuan J, Leung DYC, Leung MKH, Nic M and Wang H, Chemical and transport behaviors in a microfluidic reformer with catalytic-support membrane for efficient hydrogen production and purification. Int J Hydrogen Energy 37:2614–2622 (2012).
103. Hägg MB, Membrane purification of Cl 2 gas: I. permeabilities as a function of temperature for Cl2, O2, N2, H2 in two types of PDMS membranes. J Membr Sci 170:173–190 (2000).
104. Toda K, Ohira SI and Ikeda M, Micro-gas analysis system µGAS comprising a microchannel scrubber and a micro-fluorescence detector for measurement of hydrogen sulfide. J Anal Chimica Acta 511:3–10 (2004).
105. Goto S, Assabumrungrat S, Tagawa T and Praserthdam P, The effect of direction of hydrogen permeation on the rate through a composite palladium membrane. J Membr Sci 175:19–24 (2000).
106. Timmer B, Olthuis W and van den Berg A, Sampling small volumes of ambient ammonia using a miniaturized gas sampler. J Lab on a Chip 4:252–255 (2004).
107. Ohira SI, Toda K, Ikebe SI and Dasgupta PK, Hybrid microfabricated device for field measurement of atmospheric sulfur dioxide. J Anal Chem 74:5890–5896 (2002).
108. Ohira SI and Toda K, Micro gas analysis system for measurement of atmospheric hydrogen sulfide and sulfur dioxide. J Lab on a Chip 5:1374–1379 (2005).
109. Mitrovski SM and Nuzzo RG, An electrochemically driven poly (dimethylsiloxane) microfluidic actuator: oxygen sensing and programmable flows and pH gradients. J Lab on a Chip 5:634–645 (2005).
110. Wu CC, Yasukawa T, Shiku H and Matsue T, Fabrication of miniature Clark oxygen sensor integrated with microstructure. J Sensors Actuators B: Chem 110:342–349 (2005).
111. Liu C, Thompson JA and Bau HH, A membrane-based, high-efficiency, microfluidic debubbler. J Lab on a Chip 11:1688–1693 (2011).
112. Xu J, Vaillant R and Attinger D, Use of a porous membrane for gas bubble removal in microfluidic channels: physical mechanisms and design criteria. J Microfluidics Nanofluidics 9:765–772 (2010).
113. Johnson M, Liddiard G, Eddings M and Gale B, Bubble inclusion and removal using PDMS membrane-based gas permeation for applications in pumping, valving and mixing in microfluidic devices. J Micromech Microeng 19:095011 (2009).
114. Arakawa T, Yamamoto T and Shoji S, Micro-bubble formation with organic membrane in a multiphase microfluidic system. J Sensors Actuators A: Phys 143:58–63 (2008).
115. Jeong WC, Kim SH and Yang SM, Photothermal control of membrane permeability of microcapsules for on-demand release. J ACS Appl Mater Interfaces 6:826–832 (2014).
116. Gao D, Liu H, Lin JM, Wang Y and Jiang Y, Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device. J Lab on a Chip 13:978–985 (2013).
117. Kuhn P, Eyer K, Allner S, Lombardi D and Dittrich PS, A microfluidic vesicle screening platform: monitoring the lipid membrane permeability of tetracyclines. J Anal Chem 83:8877–8885 (2011).
118. Tan F, Leung PHM, Liu Z, Zhang Y, Xiao L and Ye W, A PDMS microfluidic impedance immunosensor for E. coli O157: H7 and Staphylococcus aureus detection via antibody-immobilized nanoporous membrane. J Sensors Actuators B: Chem 159:328–335 (2011).
119. Li L, Fu Q, Kors CA, Stewart L, Nollert P, Laible PD et al., A plug-based microfluidic system for dispensing lipidic cubic phase (LCP) material validated by crystallizing membrane proteins in lipidic mesophases. J Microfluidics Nanofluidics 8(6):789–798 (2010).
120. Gao D, Liu H, Lin JM, Wang Y and Jiang Y, Characterization of drug permeability in Caco-2 monolayers by mass spectrometry on a membrane-based microfluidic device. J Lab on a Chip 13:978–985 (2013).
121. Jiang Y, Wang PC, Locascio LE and Lee CS, Integrated plastic microfluidic devices with ESI-MS for drug screening and residue analysis. J Anal Chem 73:2048–2053 (2001).
122. Tokuyama T, Fujii S, Sato K, Abo M and Okubo A, Microbioassay system for antiallergic drug screening using suspension cells retaining in a poly (dimethylsiloxane) microfluidic device. J Anal Chem 77:3309–3314 (2005).
123. Iannacone JM, Jakubowski JA, Bohn PW and Sweedler JV, A multilayer poly (dimethylsiloxane) electrospray ionization emitter for sample injection and online mass spectrometric detection. J Electrophoresis 26:4684–4690 (2005).
124. Wang YX, Cooper JW, Lee CS and DeVoe DL, Efficient electrospray ionization from polymer microchannels using integrated hydrophobic membranes. J Lab on a Chip 4:363–367 (2004).
125. Yue GE, Roper MG, Jeffery ED, Easley CJ, Balchunas C and Landers JP et al., Glass microfluidic devices with thin membrane voltage junctions for electrospray mass spectrometry. J Lab on a Chip 5:619–627 (2005).
126. Khandurina J, Jacobson SC, Waters LC, Foote RS and Ramsey JM, Microfabricated porous membrane structure for sample concentration and electrophoretic analysis. J Anal Chem 71:1815–1819 (1999).
127. Kuo TC, Cannon DM, Chen Y, Tulock JJ, Shannon MA, Sweedler JV et al., Gateable nanofluidic interconnects for multilayered microfluidic separation systems. J Anal Chem 75:1861–1867 (2003).
128. Cannon DM, Kuo TC, Bohn PW and Sweedler JV, Nanocapillary array interconnects for gated analyte injections and electrophoretic separations in multilayer microfluidic architectures. J Anal Chem 75:2224–2230 (2003).
129. Tulock JJ, Shannon MA, Bohn PW and Sweedler JV, Microfluidic separation and gateable fraction collection for mass-limited samples. J Anal Chem 76:6419–6425 (2004).
130. Scholes CA, Stevens GW and Kentish SE, The effect of hydrogen sulfide, carbon monoxide and water on the performance of a PDMS membrane in carbon dioxide/nitrogen separation. J Membr Sci 350:189–199 (2010).
131. Song YA, Batista C, Sarpeshkar R and Han J, Rapid fabrication of microfluidic polymer electrolyte membrane fuel cell in PDMS by surface patterning of perfluorinated ion-exchange resin. J Power Sources 183:674–677 (2008).
132. Shah K, Shin WC and Besser RS, A PDMS micro proton exchange membrane fuel cell by conventional and non-conventional microfabrication techniques. J Sensors Actuators B: Chem 97:157–167 (2004).
133. Mitrovski SM, Elliott LCC and Nuzzo RG, Microfluidic devices for energy conversion: planar integration and performance of a passive, fully immersed H2–O2 fuel cell. J Langmuir 20:6974–6976 (2004).
134. Liu V, Song YA and Han J, Capillary-valve-based fabrication of ion-selective membrane junction for electrokinetic sample preconcentration in PDMS chip. J Lab on a Chip 10:1485–1490 (2010).
135. Timmer BH, Van Delft KM, Olthuis W, Bergveld P and van den Berg A, Micro-evaporation electrolyte concentrator. J Sensors Actuators B: Chem 91:342–346 (2003).
136. Kim JH, Lau KT, Shepherd R, Wu Y, Wallace G and Diamond D, Performance characteristics of a polypyrrole modified polydimethylsiloxane (PDMS) membrane based microfluidic pump. J Sensors Actuators A: Phys 148:239–244 (2008).
137. Tseng HY, Wang CH, Lin WY and Lee GB, Membrane-activated microfluidic rotary devices for pumping and mixing. J Biomed Microdevices 9:545–554 (2007).
138. Meng DD, Micropumping of liquid by directional growth and selective venting of gas bubbles. J Lab on a Chip 8:958–968 (2008).
139. Abate AR and Weitz DA, Single-layer membrane valves for elastomeric microfluidic devices. J Appl Phys Lett 92:243509 (2008).
140. Robinson T, Kuhn P, Eyer K and Dittrich PS, Microfluidic trapping of giant unilamellar vesicles to study transport through a membrane pore. J Biomicrofluidics 7:044105 (2013).
141. Hansson J, Hillmering M, Haraldsson T and van der Wijngaart W, Leak-tight vertical membrane microvalves. J Lab on a Chip 16:1439–1446 (2016).
142. Noblitt SD, Kraly JR, VanBuren JM, Hering SV, Collett JL, Jr and Henry CS, Integrated membrane filters for minimizing hydrodynamic flow and filtering in microfluidic devices. J Anal Chem 79:6249–6254 (2007).
143. Yagyu H, Hirai Y, Makino Y, Sugano K, Toshiyuki T and Tabata O, Investigation of molecular diffusivity of photoresist membrane using coarse-grained molecular dynamics simulation. J Procedia Eng 47:402–405 (2012).
144. Hylton K and Mitra S, A microfluidic hollow fiber membrane extractor for arsenic (V) detection. J Anal Chimica Acta 607:45–49 (2008).
145. Floriano PN, Christodoulides N, Romanovicz D, Bernarda B, Simmonsa GW, Cavell M et al., Membrane-based on-line optical analysis system for rapid detection of bacteria and spores. J Biosensors Bioelectron 20:2079–2088 (2005).
146. Dorokhin D, Crespo GA, Afshar MG and Bakker E, A low-cost thin layer coulometric microfluidic device based on an ion-selective membrane for calcium determination. J Analyst 139:48–51 (2014).
147. Wu P, Field RW, England R and Brisdon BJ, A fundamental study of organofunctionalised PDMS membranes for the pervaporative recovery of phenolic compounds from aqueous streams. J Membr Sci 190:147–157 (2001).
148. Sridharamurthy SS, Dong L and Jiang H, A microfluidic chemical/biological sensing system based on membrane dissolution and optical absorption. J Measurement Sci Technol 18:201 (2006).
149. Lee SH, Oh EH and Park TH. Cell-based microfluidic platform for mimicking human olfactory system. J Biosens Bioelectron 74:554–561 (2015).
150. Vladisavljević GT, Laouini A, Charcosset C, Fessi H, Bandulasena HCH and Holdicha RG, Production of liposomes using microengineered membrane and co-flow microfluidic device. J Colloids Surfaces A: Physicochem Eng Aspects 458:168–177 (2014).
151. Fa K, Tulock JJ, Sweedler JV and Bohn PW, Profiling pH gradients across nanocapillary array membranes connecting microfluidic channels. J Am Chem Soc 127:13928–13933 (2005).
152. To N, Sanada I, Ito H, Prihandana GS, Morita S, Kanno Y et al., Water-permeable dialysis membranes for multi-layered microdialysis system. Frontiers in bioengineering and biotechnology 3:70 (2015).
153. Kurita R, Yabumoto N and Niwa O, Miniaturized one-chip electrochemical sensing device integrated with a dialysis membrane and double thin-layer flow channels for measuring blood samples. J Biosensors Bioelectron 21:1649–1653 (2006).
154. Tudorache M and Emnéus J, A micro-immuno supported liquid membrane assay (µ-ISLMA). J Biosensors Bioelectron 21:1513–1520 (2006).
155. Hsieh YC and Zahn JD, Glucose recovery in a microfluidic microdialysis biochip. J Sensors Actuators B: Chem 107:649–656 (2005).