Overexpression of SIRT1 in vascular smooth muscle cells attenuates angiotensin II-induced vascular remodeling and hypertension in mice

Journal of Molecular Medicine

Volumn 92, Issue 4, 2014, Pages 347-357

  Gao, Peng ^a   Xu, Ting Ting ^a   Lu, Jie ^a   Li, Li ^a   Xu, Jing ^a   Hao, De Long ^a   Chen, Hou Zao ^a   Liu, De Pei ^a  

^a INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Hypertension; SIRT1; Vascular remodeling; Vascular smooth muscle cell

Indexed keywords

ANGIOTENSIN II; COLLAGEN; REACTIVE OXYGEN METABOLITE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; SIRTUIN 1; TRANSFORMING GROWTH FACTOR BETA1; SIRT1 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY WALL; ARTICLE; BINDING SITE; CARDIOVASCULAR INFLAMMATION; COLLAGEN SYNTHESIS; CONTROLLED STUDY; HYPERTENSION; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SYSTOLIC BLOOD PRESSURE; THORACIC AORTA; TRANSGENE; VASCULAR DISEASE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE; ANIMAL; AORTA; C57BL MOUSE; CHEMICALLY INDUCED; ENZYMOLOGY; GENE EXPRESSION; GENETIC EPIGENESIS; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SMOOTH MUSCLE FIBER; TRANSGENIC MOUSE; VASCULITIS;

ANGIOTENSIN II; ANIMALS; AORTA; EPIGENESIS, GENETIC; GENE EXPRESSION; HYPERTENSION; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; REACTIVE OXYGEN SPECIES; SIRTUIN 1; VASCULITIS;

EID: 84898020293     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-013-1111-4     Document Type: Article

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