Dynamic culture yields engineered myocardium with near-adult functional output

Biomaterials

Volumn 111, Issue , 2016, Pages 66-79

  Jackman, Christopher P ^a   Carlson, Aaron L ^a   Bursac, Nenad ^a  

^a Duke University   (United States)

Author keywords

Cardiac tissue engineering; Conduction velocity; Contractile function; Human pluripotent stem cells; mTOR

Indexed keywords

ANTIBIOTICS; CELL ENGINEERING; DYNAMICS; ELECTROPHYSIOLOGY; HEART; HISTOLOGY; RATS; STEM CELLS; TISSUE ENGINEERING; VELOCITY;

CARDIAC TISSUE ENGINEERING; CONDUCTION VELOCITY; MECHANICAL STIMULATION; MECHANOSENSITIVE CHANNEL; MTOR; NEONATAL RAT CARDIOMYOCYTES; NUTRIENT AVAILABILITY; PLURIPOTENT STEM CELLS;

TISSUE;

ACTIN; ADENYLATE KINASE; CAVEOLIN 3; COLLAGEN TYPE 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHENYLEPHRINE; RAPAMYCIN; RNA; FIBRIN;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; ENGINEERED HEART TISSUE; ENZYME PHOSPHORYLATION; FUNCTIONAL ASSESSMENT; HEART CONDUCTION; HEART DEVELOPMENT; HEART FUNCTION; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE POTENTIAL; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROGEL; MATURATION; MECHANICAL STIMULATION; MECHANOTRANSDUCTION; MUSCLE TWITCH; NEWBORN; NONHUMAN; NUTRIENT AVAILABILITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TISSUE ENGINEERING; ANIMAL; BIOARTIFICIAL ORGAN; CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DEVICES; GROWTH, DEVELOPMENT AND AGING; HEART; HEART CONTRACTION; HEART MUSCLE CONDUCTION SYSTEM; ORGAN CULTURE TECHNIQUE; PHYSIOLOGY; PROCEDURES; TISSUE SCAFFOLD;

ANIMALS; BIOARTIFICIAL ORGANS; CELL PROLIFERATION; CELLS, CULTURED; FIBRIN; HEART; HEART CONDUCTION SYSTEM; HUMANS; HYDROGELS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; ORGAN CULTURE TECHNIQUES; RATS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84991461538     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.09.024     Document Type: Article

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