Voltage-sensitive dye mapping in Langendorff-perfused rat hearts

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Nygren, A ^a   Kondo, C ^a   Clark, R B ^a   Giles, W R ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

Fluorescent dyes; Imaging techniques; Rat heart ventricular activation

Indexed keywords

DYE; PYRIDINIUM DERIVATIVE;

ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR BLOCK; ELECTRIC POTENTIAL; ELECTROCARDIOGRAM; HEART CONDUCTION; HEART LEFT VENTRICLE; HEART PERFUSION; HEART RHYTHM; HEART RIGHT VENTRICLE; HYPOKALEMIA; ISOLATED HEART; NONHUMAN; POTASSIUM CELL LEVEL; PRIORITY JOURNAL; RAT; SINUS RHYTHM; VASODILATATION; VELOCITY;

EID: 0037372227     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00648.2002     Document Type: Article

References (40)

1. Baker LC, London B, Choi BR, Koren G, and Salama G. Enhanced dispersion of repolarization and refractoriness in transgenic mouse hearts promotes reentrant ventricular tachycardia. Circ Res 86: 396-407, 2000.
2. Brandes R, Figueredo VM, Camacho SA, Massie BM, and Weiner MW. Suppression of motion artifacts in fluorescence spectroscopy of perfused hearts. Am J Physiol Heart Circ Physiol 263: H972-H980, 1992.
3. Coulombe A, Lefevre IA, Deroubaix E, Thuringer D, and Coraboeuf E. Effect of 2,3-butanedione 2-monoxime on slow inward and transient outward currents in rat ventricular myocytes. J Mol Cell Cardiol 22: 921-932, 1990.
4. Dalton GR, Jones JV, Evans SJ, and Levi AJ. Wall stress-induced arrhythmias in the working rat heart as left ventricular hypertrophy regresses during captopril treatment. Cardiovasc Res 33: 561-572, 1997.
5. Durrer D, Van Dam RT, Freud GE, Janse MJ, Meijler FL, and Arzbaecher RC. Total excitation of the isolated human heart. Circulation 41: 899-912, 1970.
6. Efimov IR, Huang DT, Rendt JM, and Salama G. Optical mapping of repolarization and refractoriness from intact hearts. Circulation 90: 1469-1480, 1994.
7. Entcheva E, Lu SN, Troppman RH, Sharma V, and Tung L. Contact fluorescence imaging of reentry in monolayers of cultured neonatal rat ventricular myocytes. J Cardiovasc Electrophysiol 11: 665-676, 2000.
8. Frey N, Franz WM, Gloeckner K, Degenhardt M, Muller M, Muller O, Merz H, and Katus HA. Transgenic rat hearts expressing a human cardiac troponin T deletion reveal diastolic dysfunction and ventricular arrhythmias. Cardiovasc Res 47: 254-264, 2000.
9. Girouard SD, Laurita KR, and Rosenbaum DS. Unique properties of cardiac action potentials recorded with voltage-sensitive dyes. J Cardiovasc Electrophysiol 7: 1024-1038, 1996.
10. Gray RA, Pertsov AM, and Jalife J. Spatial and temporal organization during cardiac fibrillation. Nature 392: 75-78, 1998.
11. Hille B. Ion Channels of Excitable Membranes. Sunderland, MA: Sinauer, 2001.
12. Hofer E, Urban G, Spach MS, Schafferhofer I, Mohr G, and Platzer D. Measuring activation patterns of the heart at a microscopic size scale with thin-film sensors. Am J Physiol Heart Circ Physiol 266: H2136-H2145, 1994.
13. Jacob HJ and Kwitek AE. Rat genetics: attaching physiology and pharmacology to the genome. Nat Rev Genet 3: 33-42, 2002.
14. Kagiyama Y, Hill JL, and Gettes LS. Interaction of acidosis and increased extracellular potassium on action potential characteristics and conduction in guinea pig ventricular muscle. Circ Res 51: 614-623, 1982.
15. Klebér AG, Janse MJ, and Fast VG. Normal and abnormal conduction in the heart. In: Handbook of Physiology. The Cardiovascular System. The Heart. Bethesda, MD: Am. Physiol. Soc., 2001, sect. 2, vol. 1, chapt. 12, p. 455-530.
16. Knisley SB, Justice RK, Kong W, and Johnson PL. Ratiometry of transmembrane voltage-sensitive fluorescent dye emission in hearts. Am J Physiol Heart Circ Physiol 279: H1421-H1433, 2000.
17. + channels. J Physiol 492: 419-430, 1996.
18. Larsen TS, Belke DD, Sas R, Giles WR, Severson DL, Lopaschuk GD, and Tyberg JV. The isolated working mouse heart: methodological considerations. Pflügers Arch 437: 979-985, 1999.
19. Laurita KR, Girouard SD, and Rosenbaum DS. Modulation of ventricular repolarization by a premature stimulus. Role of epicardial dispersion of repolarization kinetics demonstrated by optical mapping of the intact guinea pig heart. Circ Res 79: 493-503, 1996.
20. +] dependence of polyamine-induced rectification in inward rectifier potassium channels (IRK1, Kir2.1). J Gen Physiol 108: 105-113, 1996.
21. Macchi E, Cavalieri M, Stilli D, Musso E, Baruffi S, Olivetti G, Ershler PR, Lux RL, and Taccardi B. High-density epicardial mapping during current injection and ventricular activation in rat hearts. Am J Physiol Heart Circ Physiol 275: H1886-H1897, 1998.
22. Marian AJ, Wu Y, Lim DS, McCluggage M, Youker K, Yu QT, Brugada R, DeMayo F, Quinones M, and Roberts R. A transgenic rabbit model for human hypertrophic cardiomyopathy. J Clin Invest 104: 1683-1692, 1999.
23. Marshall E. Rat genome spurs an unusual partnership. Science 291: 1872, 2001.
24. Moravec M and Moravec J. Presence of mechanoreceptors in the atrioventricular junction of the rat heart: microanatomical and ultrastructural evidences. J Ultrastruct Res 81: 47-65, 1982.
25. Moravec M and Moravec J. 3-D characterization of ganglion cells of the terminal nerve plexus of rat atrioventricular junction. J Auton Nerv Syst 74: 1-12, 1998.
26. Morley GE, Vaidya D, Samie FH, Lo C, Delmar M, and Jalife J. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J Cardiovasc Electrophysiol 10: 1361-1375, 1999.
27. Nygren A, Clark RB, Belke DD, Kondo C, Giles WR, and Witkowski FX. Voltage-sensitive dye mapping of activation and conduction in adult mouse hearts. Ann Biomed Eng 28: 958-967, 2000.
28. +] in a human atrial strand. Ann Biomed Eng 28: 951-957, 2000.
29. Paul M, Wagner J, Hoffmann S, Urata H, and Ganten D. Transgenic rats: new experimental models for the study of candidate genes in hypertension research. Annu Rev Physiol 56: 811-829, 1994.
30. Pinto JM and Boyden PA. Electrical remodeling in ischemia and infarction. Cardiovasc Res 42: 284-297, 1999.
31. Quayle JM, Dart C, and Standen NB. The properties and distribution of inward rectifier potassium currents in pig coronary arterial smooth muscle. J Physiol 494: 715-726, 1996.
32. Rohr S and Kucera JP. Optical recording system based on a fiber optic image conduit: assessment of microscopic activation patterns in cardiac tissue. Biophys J 75: 1062-1075, 1998.
33. Shaw RM and Rudy Y. Electrophysiologic effects of acute myocardial ischemia: a mechanistic investigation of action potential conduction and conduction failure. Circ Res 80: 124-138, 1997.
34. Smeets JLRM, Allessie MA, Lammers WJEP, Bonke FIM, and Hollen J. The wavelength of the cardiac impulse and reentrant arrhythmias in isolated rabbit atrium: the role of heart rate, autonomic transmitters, temperature, and potassium. Circ Res 58: 96-108, 1986.
35. Suzuki J, Tsubone H, and Sugano S. Characteristics of ventricular activation and recovery patterns in the rat. J Vet Med Sci 54: 711-716, 1992.
36. Tamaddon HS, Vaidya D, Simon AM, Paul DL, Jalife J, and Morley GE. High-resolution optical mapping of the right bundle branch in Connexin40 knockout mice reveals slow conduction in the specialized conduction system. Circ Res 87: 929-936, 2000.
37. Uzzaman M, Honjo H, Takagishi Y, Endad L, Magee AI, Severs NJ, and Kodama I. Remodeling of gap junctional coupling in hypertrophied right ventricles of rats with monocrotaline-induced pulmonary hypertension. Circ Res 86: 871-878, 2000.
38. Watanabe T, Delbridge LM, Bustamante JO, and McDonald TF. Heterogeneity of the action potential in isolated rat ventricular myocytes and tissue. Circ Res 52: 280-290, 1983.
39. Witkowski FX, Leon LJ, Penkoske PA, Clark RB, Spano ML, Ditto WL, and Giles WR. A method for visualization of ventricular fibrillation: Design of a cooled fiberoptically coupled image intensified CCD data acquisition system incorporating wavelet shrinkage based adaptive filtering. CHAOS 8: 94-102, 1998.
40. Witkowski FX, Leon LJ, Penkoske PA, Giles WR, Spano ML, Ditto WL, and Winfree AT. Spatiotemporal evolution of ventricular fibrillation. Nature 392: 78-82, 1998.