Deciphering the microRNA signature of pathological cardiac hypertrophy by engineered heart tissue- and sequencing-technology

Journal of Molecular and Cellular Cardiology

Volumn 81, Issue , 2015, Pages 1-9

  Hirt, Marc N ^a,b   Werner, Tessa ^a,b   Indenbirken, Daniela ^c   Alawi, Malik ^a,c   Demin, Paul ^a   Kunze, Ann Cathrin ^a,b   Stenzig, Justus ^a,b   Starbatty, Jutta ^a,b   Hansen, Arne ^a,b   Fiedler, Jan ^d   Thum, Thomas ^d   Eschenhagen, Thomas ^a,b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^c LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Anti miR; Cardiac hypertrophy; Engineered heart tissue; MicroRNA; Next generation sequencing

Indexed keywords

MICRORNA; MICRORNA 133A 3P; MICRORNA 133A 5P; MICRORNA 140 3P; MICRORNA 21 3P; MICRORNA 21 5P; MICRORNA 210 3P; MICRORNA 210 5P; MICRORNA 30C 3P; MICRORNA 30C 5P; MICRORNA 30E 3P; MICRORNA 30E 5P; MICRORNA 322 3P; MICRORNA 322 5P; UNCLASSIFIED DRUG; ANTISENSE OLIGONUCLEOTIDE; MIRN21 MICRORNA, RAT; TRANSCRIPTOME;

AFTERLOAD ENHANCEMENT; ANIMAL CELL; ARTICLE; ARTIFICIAL ORGANS, TISSUES AND CELLS; CARDIOVASCULAR PARAMETERS; COMPARATIVE STUDY; CONTRACTILE FORCE VELOCITY; CONTROLLED STUDY; DOWN REGULATION; ENGINEERED HEART TISSUE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE REACTIVATION; GENETIC ASSOCIATION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IN VITRO STUDY; NEWBORN; NEXT GENERATION SEQUENCING; NONHUMAN; PATHOLOGICAL CARDIAC HYPERTROPHY; PHENOTYPE; PRIORITY JOURNAL; RAT; RELAXATION VELOCITY; RNA ANALYSIS; RNA EXTRACTION; RNA SEQUENCE; UPREGULATION; ANIMAL; BIOLOGICAL MODEL; CARDIOMEGALY; FIBROSIS; GENETICS; HEART CONTRACTION; LEWIS RAT; METABOLISM; PATHOLOGY; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; CARDIOMEGALY; FIBROSIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICRORNAS; MODELS, CARDIOVASCULAR; MYOCARDIAL CONTRACTION; OLIGORIBONUCLEOTIDES, ANTISENSE; RATS; RATS, INBRED LEW; RATS, WISTAR; SEQUENCE ANALYSIS, RNA; SIGNAL TRANSDUCTION; TISSUE ENGINEERING; TRANSCRIPTOME;

EID: 84950274002     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2015.01.008     Document Type: Article

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