KDM4A Coactivates E2F1 to Regulate the PDK-Dependent Metabolic Switch between Mitochondrial Oxidation and Glycolysis

Cell Reports

Volumn 16, Issue 11, 2016, Pages 3016-3027

  Wang, Ling Yu ^a   Hung, Chiu Lien ^a,e   Chen, Yun Ru ^b   Yang, Joy C ^c   Wang, Junjian ^a   Campbell, Mel ^a   Izumiya, Yoshihiro ^a   Chen, Hong Wu ^a   Wang, Wen Ching ^d   Ann, David K ^b   Kung, Hsing Jien ^a,e  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^e NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE DEMETHYLASE 4A; PYRUVATE DEHYDROGENASE KINASE; PYRUVATE DEHYDROGENASE KINASE 1; PYRUVATE DEHYDROGENASE KINASE 3; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; CHROMATIN; E2F1 PROTEIN, HUMAN; HISTONE DEMETHYLASE; KDM4A PROTEIN, HUMAN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING SITE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; GENE TARGETING; GLYCOLYSIS; HUMAN; HUMAN CELL; MALE; METABOLIC REGULATION; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; PROTEIN TARGETING; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; CHROMATIN; GENE EXPRESSION REGULATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MITOCHONDRION; NUCLEOTIDE SEQUENCE; NUDE MOUSE; OXIDATION REDUCTION REACTION; PHENOTYPE; PROSTATE TUMOR; TUMOR CELL LINE;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CELL PROLIFERATION; CHROMATIN; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GLYCOLYSIS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; MALE; MICE, NUDE; MITOCHONDRIA; OXIDATION-REDUCTION; PHENOTYPE; PROSTATIC NEOPLASMS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; TRANSCRIPTION, GENETIC;

EID: 84991384391     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.08.018     Document Type: Article

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