메뉴 건너뛰기




Volumn 22, Issue 9, 2015, Pages 1185-1196

KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; HISTONE DEMETHYLASE; JMD2 HISTONE DEMETHYLASE INHIBITOR; KDM4 HISTONE DEMETHYLASE INHIBITOR; POLO LIKE KINASE 1; PROTEIN BMYB; SMALL INTERFERING RNA; TUMOR PROTEIN; UNCLASSIFIED DRUG; AR PROTEIN, HUMAN; CELL CYCLE PROTEIN; KDM4B PROTEIN, HUMAN; ONCOPROTEIN; POLO-LIKE KINASE 1; PROTEIN SERINE THREONINE KINASE;

EID: 84941935866     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2015.08.007     Document Type: Article
Times cited : (65)

References (40)
  • 1
    • 84877861510 scopus 로고    scopus 로고
    • KDM4/JMJD2 histone demethylases: Epigenetic regulators in cancer cells
    • W.L. Berry, and R. Janknecht KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Cancer Res. 73 2013 2936 2942
    • (2013) Cancer Res. , vol.73 , pp. 2936-2942
    • Berry, W.L.1    Janknecht, R.2
  • 2
    • 84870375316 scopus 로고    scopus 로고
    • Histone lysine methylation dynamics: Establishment, regulation, and biological impact
    • J.C. Black, C. Van Rechem, and J.R. Whetstine Histone lysine methylation dynamics: establishment, regulation, and biological impact Mol. Cell 48 2012 491 507
    • (2012) Mol. Cell , vol.48 , pp. 491-507
    • Black, J.C.1    Van Rechem, C.2    Whetstine, J.R.3
  • 3
    • 0028866537 scopus 로고
    • Identification and functional characterization of the human and murine polo-like kinase (Plk) promoter
    • A. Bräuninger, K. Strebhardt, and H. Rübsamen-Waigmann Identification and functional characterization of the human and murine polo-like kinase (Plk) promoter Oncogene 11 1995 1793 1800
    • (1995) Oncogene , vol.11 , pp. 1793-1800
    • Bräuninger, A.1    Strebhardt, K.2    Rübsamen-Waigmann, H.3
  • 7
    • 84890278751 scopus 로고    scopus 로고
    • The role of polo-like kinase 1 in carcinogenesis: Cause or consequence?
    • D. Cholewa, X. Liu, and N. Ahmad The role of polo-like kinase 1 in carcinogenesis: cause or consequence? Cancer Res. 73 2013 6848 6855
    • (2013) Cancer Res. , vol.73 , pp. 6848-6855
    • Cholewa, D.1    Liu, X.2    Ahmad, N.3
  • 10
    • 84903184496 scopus 로고    scopus 로고
    • Current assessment of polo-like kinases as anti-tumor drug targets
    • S.N. Craig, M.D. Wyatt, and C. McInnes Current assessment of polo-like kinases as anti-tumor drug targets Expert Opin. Drug Discov. 9 2014 773 789
    • (2014) Expert Opin. Drug Discov. , vol.9 , pp. 773-789
    • Craig, S.N.1    Wyatt, M.D.2    McInnes, C.3
  • 12
    • 77954025117 scopus 로고    scopus 로고
    • Epigenetic regulation of androgen receptor signaling in prostate cancer
    • L. Gao, and J. Alumkal Epigenetic regulation of androgen receptor signaling in prostate cancer Epigenetics 5 2010 100 104
    • (2010) Epigenetics , vol.5 , pp. 100-104
    • Gao, L.1    Alumkal, J.2
  • 14
    • 77955345001 scopus 로고    scopus 로고
    • Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors
    • S. Hamada, T. Suzuki, K. Mino, K. Koseki, F. Oehme, I. Flamme, H. Ozasa, Y. Itoh, D. Ogasawara, H. Komaarashi, and et al. Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors J. Med. Chem. 53 2010 5629 5638
    • (2010) J. Med. Chem. , vol.53 , pp. 5629-5638
    • Hamada, S.1    Suzuki, T.2    Mino, K.3    Koseki, K.4    Oehme, F.5    Flamme, I.6    Ozasa, H.7    Itoh, Y.8    Ogasawara, D.9    Komaarashi, H.10
  • 15
    • 79958217709 scopus 로고    scopus 로고
    • The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility
    • N. Iwamori, M. Zhao, M.L. Meistrich, and M.M. Matzuk The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility Biol. Reprod. 84 2011 1225 1234
    • (2011) Biol. Reprod. , vol.84 , pp. 1225-1234
    • Iwamori, N.1    Zhao, M.2    Meistrich, M.L.3    Matzuk, M.M.4
  • 16
    • 34249765651 scopus 로고
    • NMR view: A computer program for the visualization and analysis of NMR data
    • B.A. Johnson, and R.A. Blevins NMR view: a computer program for the visualization and analysis of NMR data J. Biomol. NMR 4 1994 603 614
    • (1994) J. Biomol. NMR , vol.4 , pp. 603-614
    • Johnson, B.A.1    Blevins, R.A.2
  • 17
    • 16544389546 scopus 로고    scopus 로고
    • Identification and characterization of JMJD2 family genes in silico
    • M. Katoh, and M. Katoh Identification and characterization of JMJD2 family genes in silico Int. J. Oncol. 24 2004 1623 1628
    • (2004) Int. J. Oncol. , vol.24 , pp. 1623-1628
    • Katoh, M.1    Katoh, M.2
  • 18
    • 79952800100 scopus 로고    scopus 로고
    • Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development
    • M. Kawazu, K. Saso, K.I. Tong, T. McQuire, K. Goto, D.O. Son, A. Wakeham, M. Miyagishi, T.W. Mak, and H. Okada Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development PLoS One 6 2011 e17830
    • (2011) PLoS One , vol.6 , pp. e17830
    • Kawazu, M.1    Saso, K.2    Tong, K.I.3    McQuire, T.4    Goto, K.5    Son, D.O.6    Wakeham, A.7    Miyagishi, M.8    Mak, T.W.9    Okada, H.10
  • 19
    • 78649528262 scopus 로고    scopus 로고
    • Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors
    • O.N. King, X.S. Li, M. Sakurai, A. Kawamura, N.R. Rose, S.S. Ng, A.M. Quinn, G. Rai, B.T. Mott, P. Beswick, and et al. Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors PLoS One 23 2010 e15535
    • (2010) PLoS One , vol.23 , pp. e15535
    • King, O.N.1    Li, X.S.2    Sakurai, M.3    Kawamura, A.4    Rose, N.R.5    Ng, S.S.6    Quinn, A.M.7    Rai, G.8    Mott, B.T.9    Beswick, P.10
  • 21
    • 84894283946 scopus 로고    scopus 로고
    • The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development
    • M.T. Pedersen, K. Agger, A. Laugesen, J.V. Johansen, P.A. Cloos, J. Christensen, and K. Helin The demethylase JMJD2C localizes to H3K4me3-positive transcription start sites and is dispensable for embryonic development Mol. Cell Biol. 34 2014 1031 1045
    • (2014) Mol. Cell Biol. , vol.34 , pp. 1031-1045
    • Pedersen, M.T.1    Agger, K.2    Laugesen, A.3    Johansen, J.V.4    Cloos, P.A.5    Christensen, J.6    Helin, K.7
  • 24
    • 84867409614 scopus 로고    scopus 로고
    • Enlightening molecular mechanisms through study of protein interactions
    • J. Rizo, M.K. Rosen, and K.H. Gardner Enlightening molecular mechanisms through study of protein interactions J. Mol. Cell Biol. 4 2012 270 283
    • (2012) J. Mol. Cell Biol. , vol.4 , pp. 270-283
    • Rizo, J.1    Rosen, M.K.2    Gardner, K.H.3
  • 26
    • 84881131933 scopus 로고    scopus 로고
    • The DREAM complex: Master coordinator of cell cycle-dependent gene expression
    • S. Sadasivam, and J.A. DeCaprio The DREAM complex: master coordinator of cell cycle-dependent gene expression Nat. Rev. Cancer 13 2013 585 595
    • (2013) Nat. Rev. Cancer , vol.13 , pp. 585-595
    • Sadasivam, S.1    DeCaprio, J.A.2
  • 27
    • 84857860452 scopus 로고    scopus 로고
    • The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression
    • S. Sadasivam, S. Duan, and J.A. DeCaprio The MuvB complex sequentially recruits B-Myb and FoxM1 to promote mitotic gene expression Genes Dev. 26 2012 474 489
    • (2012) Genes Dev. , vol.26 , pp. 474-489
    • Sadasivam, S.1    Duan, S.2    DeCaprio, J.A.3
  • 28
    • 34250168304 scopus 로고    scopus 로고
    • Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D
    • S. Shin, and R. Janknecht Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D Biochem. Biophys. Res. Commun. 359 2007 742 746
    • (2007) Biochem. Biophys. Res. Commun. , vol.359 , pp. 742-746
    • Shin, S.1    Janknecht, R.2
  • 29
    • 84862794545 scopus 로고    scopus 로고
    • Polo-like kinase 1 (Plk1): An unexpected player in DNA replication
    • B. Song, X.S. Liu, and X. Liu Polo-like kinase 1 (Plk1): an unexpected player in DNA replication Cell Div. 7 2012 3
    • (2012) Cell Div. , vol.7 , pp. 3
    • Song, B.1    Liu, X.S.2    Liu, X.3
  • 33
    • 77950794746 scopus 로고    scopus 로고
    • Tumor-suppressive functions of leucine zipper transcription factor-like 1
    • Q. Wei, W. Zhou, W. Wang, B. Gao, L. Wang, J. Cao, and Z.P. Liu Tumor-suppressive functions of leucine zipper transcription factor-like 1 Cancer Res. 70 2010 2942 2950
    • (2010) Cancer Res. , vol.70 , pp. 2942-2950
    • Wei, Q.1    Zhou, W.2    Wang, W.3    Gao, B.4    Wang, L.5    Cao, J.6    Liu, Z.P.7
  • 36
    • 84880543767 scopus 로고    scopus 로고
    • The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression
    • L.C. Young, and M.J. Hendzel The oncogenic potential of Jumonji D2 (JMJD2/KDM4) histone demethylase overexpression Biochem. Cell Biol. 91 2013 369 377
    • (2013) Biochem. Cell Biol. , vol.91 , pp. 369-377
    • Young, L.C.1    Hendzel, M.J.2
  • 38
    • 77957804965 scopus 로고    scopus 로고
    • Illumination of mitotic orchestra during cell division: A polo view
    • K. Yuan, Y. Huang, and X. Yao Illumination of mitotic orchestra during cell division: a polo view Cell Signal. 23 2011 1 5
    • (2011) Cell Signal. , vol.23 , pp. 1-5
    • Yuan, K.1    Huang, Y.2    Yao, X.3
  • 39
    • 84928896057 scopus 로고    scopus 로고
    • Histone methylations in heart development, congenital and adult heart diseases
    • Q.J. Zhang, and Z.P. Liu Histone methylations in heart development, congenital and adult heart diseases Epigenetics 7 2015 321 330
    • (2015) Epigenetics , vol.7 , pp. 321-330
    • Zhang, Q.J.1    Liu, Z.P.2
  • 40
    • 79957892087 scopus 로고    scopus 로고
    • The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice
    • Q.J. Zhang, H.Z. Chen, L. Wang, D.P. Liu, J.A. Hill, and Z.P. Liu The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice J. Clin. Invest. 121 2011 2447 2456
    • (2011) J. Clin. Invest. , vol.121 , pp. 2447-2456
    • Zhang, Q.J.1    Chen, H.Z.2    Wang, L.3    Liu, D.P.4    Hill, J.A.5    Liu, Z.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.