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Volumn 126, Issue 2, 2016, Pages 706-720

Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTOR; HISTONE DEMETHYLASE; INTERSTITIAL COLLAGENASE; KI 67 ANTIGEN; LYSINE SPECIFIC DEMETHYLASE 4A; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; SMOOTH MUSCLE ACTIN; TRANSCRIPTION FACTOR ER81; TRANSCRIPTION FACTOR YAP1; UNCLASSIFIED DRUG; YES ASSOCIATED PROTEIN 1; DNA BINDING PROTEIN; ETV1 PROTEIN, HUMAN; ETV1 PROTEIN, MOUSE; JMJD2A PROTEIN, MOUSE; KDM4A PROTEIN, HUMAN; PHOSPHOPROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TRANSCRIPTION FACTOR; TUMOR PROTEIN; YAP PROTEIN, MOUSE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

EID: 84956939352     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI78132     Document Type: Article
Times cited : (87)

References (73)
  • 1
    • 80053071543 scopus 로고    scopus 로고
    • Androgen receptor rediscovered: The new biology and targeting the androgen receptor therapeutically
    • Ryan CJ, Tindall DJ. Androgen receptor rediscovered: the new biology and targeting the androgen receptor therapeutically. J Clin Oncol. 2011;29(27):3651-3658.
    • (2011) J Clin Oncol , vol.29 , Issue.27 , pp. 3651-3658
    • Ryan, C.J.1    Tindall, D.J.2
  • 2
    • 77956793432 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer: New prospects for old challenges
    • Shen MM, Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 2010;24(18):1967-2000.
    • (2010) Genes Dev , vol.24 , Issue.18 , pp. 1967-2000
    • Shen, M.M.1    Abate-Shen, C.2
  • 3
    • 70350109641 scopus 로고    scopus 로고
    • ETS gene fusions in prostate cancer
    • Clark JP, Cooper CS. ETS gene fusions in prostate cancer. Nat Rev Urol. 2009;6(8):429-439.
    • (2009) Nat Rev Urol , vol.6 , Issue.8 , pp. 429-439
    • Clark, J.P.1    Cooper, C.S.2
  • 4
    • 79959466181 scopus 로고    scopus 로고
    • Genomic and biochemical insights into the specificity of ETS transcription factors
    • Hollenhorst PC, McIntosh LP, Graves BJ. Genomic and biochemical insights into the specificity of ETS transcription factors. Annu Rev Biochem. 2011;80:437-471.
    • (2011) Annu Rev Biochem , vol.80 , pp. 437-471
    • Hollenhorst, P.C.1    McIntosh, L.P.2    Graves, B.J.3
  • 5
    • 84859038513 scopus 로고    scopus 로고
    • ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors
    • Oh S, Shin S, Janknecht R. ETV1, 4 and 5: An oncogenic subfamily of ETS transcription factors. Biochim Biophys Acta. 2012;1826(1):1-12.
    • (2012) Biochim Biophys Acta , vol.1826 , Issue.1 , pp. 1-12
    • Oh, S.1    Shin, S.2    Janknecht, R.3
  • 6
    • 70350228463 scopus 로고    scopus 로고
    • Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81
    • Shin S, et al. Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81. Cancer Res. 2009;69(20):8102-8110.
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8102-8110
    • Shin, S.1
  • 7
    • 84875333536 scopus 로고    scopus 로고
    • ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients
    • Baena E, et al. ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients. Genes Dev. 2013;27(6):683-698.
    • (2013) Genes Dev , vol.27 , Issue.6 , pp. 683-698
    • Baena, E.1
  • 8
    • 84863621527 scopus 로고    scopus 로고
    • Cancer epigenetics: From mechanism to therapy
    • Dawson MA, Kouzarides T. Cancer epigenetics: from mechanism to therapy. Cell. 2012; 150(1):12-27.
    • (2012) Cell , vol.150 , Issue.1 , pp. 12-27
    • Dawson, M.A.1    Kouzarides, T.2
  • 9
    • 21744457108 scopus 로고    scopus 로고
    • Global histone modification patterns predict risk of prostate cancer recurrence
    • Seligson DB, et al. Global histone modification patterns predict risk of prostate cancer recurrence. Nature. 2005;435(7046):1262-1266.
    • (2005) Nature , vol.435 , Issue.7046 , pp. 1262-1266
    • Seligson, D.B.1
  • 10
    • 72849148472 scopus 로고    scopus 로고
    • Global levels of histone modifications predict prostate cancer recurrence
    • Ellinger J, et al. Global levels of histone modifications predict prostate cancer recurrence. Prostate. 2010;70(1):61-69.
    • (2010) Prostate , vol.70 , Issue.1 , pp. 61-69
    • Ellinger, J.1
  • 11
    • 77953995002 scopus 로고    scopus 로고
    • Covalent histone modifications - Miswritten, misinterpreted and mis-erased in human cancers
    • Chi P, Allis CD, Wang GG. Covalent histone modifications - miswritten, misinterpreted and mis-erased in human cancers. Nat Rev Cancer. 2010;10(7):457-469.
    • (2010) Nat Rev Cancer , vol.10 , Issue.7 , pp. 457-469
    • Chi, P.1    Allis, C.D.2    Wang, G.G.3
  • 12
    • 84860215207 scopus 로고    scopus 로고
    • Molecular mechanisms and potential functions of histone demethylases
    • Kooistra SM, Helin K. Molecular mechanisms and potential functions of histone demethylases. Nat Rev Mol Cell Biol. 2012;13(5):297-311.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.5 , pp. 297-311
    • Kooistra, S.M.1    Helin, K.2
  • 13
    • 84877861510 scopus 로고    scopus 로고
    • KDM4/JMJD2 histone demethylases: Epigenetic regulators in cancer cells
    • Berry WL, Janknecht R. KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells. Cancer Res. 2013;73(10):2936-2942.
    • (2013) Cancer Res , vol.73 , Issue.10 , pp. 2936-2942
    • Berry, W.L.1    Janknecht, R.2
  • 14
    • 0035959808 scopus 로고    scopus 로고
    • HER2/Neumediated activation of the ETS transcription factor ER81 and its target gene MMP-1
    • Bosc DG, Goueli BS, Janknecht R. HER2/Neumediated activation of the ETS transcription factor ER81 and its target gene MMP-1. Oncogene. 2001;20(43):6215-6224.
    • (2001) Oncogene , vol.20 , Issue.43 , pp. 6215-6224
    • Bosc, D.G.1    Goueli, B.S.2    Janknecht, R.3
  • 15
    • 33646124469 scopus 로고    scopus 로고
    • Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases
    • Whetstine JR, et al. Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases. Cell. 2006;125(3):467-481.
    • (2006) Cell , vol.125 , Issue.3 , pp. 467-481
    • Whetstine, J.R.1
  • 16
    • 33745847680 scopus 로고    scopus 로고
    • The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    • Klose RJ, et al. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36. Nature. 2006;442(7100):312-316.
    • (2006) Nature , vol.442 , Issue.7100 , pp. 312-316
    • Klose, R.J.1
  • 17
    • 33746332412 scopus 로고    scopus 로고
    • The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
    • Cloos PA, et al. The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature. 2006;442(7100):307-311.
    • (2006) Nature , vol.442 , Issue.7100 , pp. 307-311
    • Cloos, P.A.1
  • 18
    • 9144251970 scopus 로고    scopus 로고
    • Gene expression profiling identifies clinically relevant subtypes of prostate cancer
    • Lapointe J, et al. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci U S A. 2004;101(3):811-816.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , Issue.3 , pp. 811-816
    • Lapointe, J.1
  • 19
    • 34547411003 scopus 로고    scopus 로고
    • ETV1 is a novel androgen receptorregulated gene that mediates prostate cancer cell invasion
    • Cai C, et al. ETV1 is a novel androgen receptorregulated gene that mediates prostate cancer cell invasion. Mol Endocrinol. 2007;21(8):1835-1846.
    • (2007) Mol Endocrinol , vol.21 , Issue.8 , pp. 1835-1846
    • Cai, C.1
  • 20
    • 34547642493 scopus 로고    scopus 로고
    • Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer
    • Tomlins SA, et al. Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer. Nature. 2007;448(7153):595-599.
    • (2007) Nature , vol.448 , Issue.7153 , pp. 595-599
    • Tomlins, S.A.1
  • 21
    • 0034520311 scopus 로고    scopus 로고
    • A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo
    • Zhang J, Thomas TZ, Kasper S, Matusik RJ. A small composite probasin promoter confers high levels of prostate-specific gene expression through regulation by androgens and glucocorticoids in vitro and in vivo. Endocrinology. 2000;141(12):4698-4710.
    • (2000) Endocrinology , vol.141 , Issue.12 , pp. 4698-4710
    • Zhang, J.1    Thomas, T.Z.2    Kasper, S.3    Matusik, R.J.4
  • 22
    • 0036966275 scopus 로고    scopus 로고
    • Prostatic intraepithelial neoplasia in genetically engineered mice
    • Park JH, et al. Prostatic intraepithelial neoplasia in genetically engineered mice. Am J Pathol. 2002;161(2):727-735.
    • (2002) Am J Pathol , vol.161 , Issue.2 , pp. 727-735
    • Park, J.H.1
  • 23
    • 0031870959 scopus 로고    scopus 로고
    • Pten is essential for embryonic development and tumour suppression
    • Di Cristofano A, Pesce B, Cordon-Cardo C, Pandolfi PP. Pten is essential for embryonic development and tumour suppression. Nat Genet. 1998;19(4):348-355.
    • (1998) Nat Genet , vol.19 , Issue.4 , pp. 348-355
    • Di Cristofano, A.1    Pesce, B.2    Cordon-Cardo, C.3    Pandolfi, P.P.4
  • 24
    • 4243110417 scopus 로고    scopus 로고
    • Pten dose dictates cancer progression in the prostate
    • Trotman LC, et al. Pten dose dictates cancer progression in the prostate. PLoS Biol. 2003;1(3):E59.
    • (2003) PLoS Biol , vol.1 , Issue.3 , pp. E59
    • Trotman, L.C.1
  • 25
    • 84859569827 scopus 로고    scopus 로고
    • Targeting angiogenesis for the treatment of prostate cancer
    • Antonarakis ES, Carducci MA. Targeting angiogenesis for the treatment of prostate cancer. Expert Opin Ther Targets. 2012;16(4):365-376.
    • (2012) Expert Opin Ther Targets , vol.16 , Issue.4 , pp. 365-376
    • Antonarakis, E.S.1    Carducci, M.A.2
  • 26
    • 57049114832 scopus 로고    scopus 로고
    • The genetics of the p53 pathway, apoptosis and cancer therapy
    • Vazquez A, Bond EE, Levine AJ, Bond GL. The genetics of the p53 pathway, apoptosis and cancer therapy. Nat Rev Drug Discov. 2008;7(12):979-987.
    • (2008) Nat Rev Drug Discov , vol.7 , Issue.12 , pp. 979-987
    • Vazquez, A.1    Bond, E.E.2    Levine, A.J.3    Bond, G.L.4
  • 27
    • 84875476208 scopus 로고    scopus 로고
    • The Hippo pathway and human cancer
    • Harvey KF, Zhang X, Thomas DM. The Hippo pathway and human cancer. Nat Rev Cancer. 2013;13(4):246-257.
    • (2013) Nat Rev Cancer , vol.13 , Issue.4 , pp. 246-257
    • Harvey, K.F.1    Zhang, X.2    Thomas, D.M.3
  • 28
    • 84874257648 scopus 로고    scopus 로고
    • The Hippo pathway: Regulators and regulations
    • Yu FX, Guan KL. The Hippo pathway: regulators and regulations. Genes Dev. 2013;27(4):355-371.
    • (2013) Genes Dev , vol.27 , Issue.4 , pp. 355-371
    • Yu, F.X.1    Guan, K.L.2
  • 29
    • 0042591506 scopus 로고    scopus 로고
    • PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression
    • Xu LL, et al. PMEPA1, an androgen-regulated NEDD4-binding protein, exhibits cell growth inhibitory function and decreased expression during prostate cancer progression. Cancer Res. 2003;63(15):4299-4304.
    • (2003) Cancer Res , vol.63 , Issue.15 , pp. 4299-4304
    • Xu, L.L.1
  • 30
    • 57649198310 scopus 로고    scopus 로고
    • A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells
    • Li H, et al. A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells. J Biol Chem. 2008;283(43):28988-28995.
    • (2008) J Biol Chem , vol.283 , Issue.43 , pp. 28988-28995
    • Li, H.1
  • 31
    • 84872861372 scopus 로고    scopus 로고
    • ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells
    • Shin S, Oh S, An S, Janknecht R. ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells. Oncol Rep. 2013;29(1):306-314.
    • (2013) Oncol Rep , vol.29 , Issue.1 , pp. 306-314
    • Shin, S.1    Oh, S.2    An, S.3    Janknecht, R.4
  • 32
    • 67649205713 scopus 로고    scopus 로고
    • A global meta-analysis of microarray expression data to predict unknown gene functions and estimate the literature-data divide
    • Wren JD. A global meta-analysis of microarray expression data to predict unknown gene functions and estimate the literature-data divide. Bioinformatics. 2009;25(13):1694-1701.
    • (2009) Bioinformatics , vol.25 , Issue.13 , pp. 1694-1701
    • Wren, J.D.1
  • 33
    • 0029926301 scopus 로고    scopus 로고
    • Analysis of the ERK-stimulated ETS transcription factor ER81
    • Janknecht R. Analysis of the ERK-stimulated ETS transcription factor ER81. Mol Cell Biol. 1996;16(4):1550-1556.
    • (1996) Mol Cell Biol , vol.16 , Issue.4 , pp. 1550-1556
    • Janknecht, R.1
  • 34
    • 0242497921 scopus 로고    scopus 로고
    • HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81
    • Dowdy SC, Mariani A, Janknecht R. HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81. J Biol Chem. 2003;278(45):44377-44384.
    • (2003) J Biol Chem , vol.278 , Issue.45 , pp. 44377-44384
    • Dowdy, S.C.1    Mariani, A.2    Janknecht, R.3
  • 35
    • 84925381625 scopus 로고    scopus 로고
    • The Hippo pathway effector YAP regulates motility, invasion, and castrationresistant growth of prostate cancer cells
    • Zhang L, et al. The Hippo pathway effector YAP regulates motility, invasion, and castrationresistant growth of prostate cancer cells. Mol Cell Biol. 2015;35(8):1350-1362.
    • (2015) Mol Cell Biol , vol.35 , Issue.8 , pp. 1350-1362
    • Zhang, L.1
  • 36
    • 84862605178 scopus 로고    scopus 로고
    • Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP
    • Liu-Chittenden Y, et al. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes Dev. 2012;26(12):1300-1305.
    • (2012) Genes Dev , vol.26 , Issue.12 , pp. 1300-1305
    • Liu-Chittenden, Y.1
  • 37
    • 84856120332 scopus 로고    scopus 로고
    • Understanding the language of Lys36 methylation at histone H3
    • Wagner EJ, Carpenter PB. Understanding the language of Lys36 methylation at histone H3. Nat Rev Mol Cell Biol. 2012;13(2):115-126.
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.2 , pp. 115-126
    • Wagner, E.J.1    Carpenter, P.B.2
  • 38
    • 23344436787 scopus 로고    scopus 로고
    • Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein
    • Gray SG, et al. Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein. J Biol Chem. 2005;280(31):28507-28518.
    • (2005) J Biol Chem , vol.280 , Issue.31 , pp. 28507-28518
    • Gray, S.G.1
  • 39
    • 22544465244 scopus 로고    scopus 로고
    • JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2)
    • Zhang D, Yoon HG, Wong J. JMJD2A is a novel N-CoR-interacting protein and is involved in repression of the human transcription factor achaete scute-like homologue 2 (ASCL2/Hash2). Mol Cell Biol. 2005;25(15):6404-6414.
    • (2005) Mol Cell Biol , vol.25 , Issue.15 , pp. 6404-6414
    • Zhang, D.1    Yoon, H.G.2    Wong, J.3
  • 40
    • 84859895529 scopus 로고    scopus 로고
    • RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites
    • Mallette FA, et al. RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites. EMBO J. 2012;31(8):1865-1878.
    • (2012) EMBO J , vol.31 , Issue.8 , pp. 1865-1878
    • Mallette, F.A.1
  • 41
    • 84881154753 scopus 로고    scopus 로고
    • KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors
    • Black JC, et al. KDM4A lysine demethylase induces site-specific copy gain and rereplication of regions amplified in tumors. Cell. 2013;154(3):541-555.
    • (2013) Cell , vol.154 , Issue.3 , pp. 541-555
    • Black, J.C.1
  • 42
    • 84924415145 scopus 로고    scopus 로고
    • Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis
    • Van Rechem C, et al. Lysine demethylase KDM4A associates with translation machinery and regulates protein synthesis. Cancer Discov. 2015;5(3):255-263.
    • (2015) Cancer Discov , vol.5 , Issue.3 , pp. 255-263
    • Van Rechem, C.1
  • 43
    • 34250168304 scopus 로고    scopus 로고
    • Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D
    • Shin S, Janknecht R. Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D. Biochem Biophys Res Commun. 2007;359(3):742-746.
    • (2007) Biochem Biophys Res Commun , vol.359 , Issue.3 , pp. 742-746
    • Shin, S.1    Janknecht, R.2
  • 44
    • 84882285291 scopus 로고    scopus 로고
    • ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss
    • Chen Y, et al. ETS factors reprogram the androgen receptor cistrome and prime prostate tumorigenesis in response to PTEN loss. Nat Med. 2013;19(8):1023-1029.
    • (2013) Nat Med , vol.19 , Issue.8 , pp. 1023-1029
    • Chen, Y.1
  • 45
    • 84920363474 scopus 로고    scopus 로고
    • Only three driver gene mutations are required for the development of lung and colorectal cancers
    • Tomasetti C, Marchionni L, Nowak MA, Parmigiani G, Vogelstein B. Only three driver gene mutations are required for the development of lung and colorectal cancers. Proc Natl Acad Sci U S A. 2015;112(1):118-123.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.1 , pp. 118-123
    • Tomasetti, C.1    Marchionni, L.2    Nowak, M.A.3    Parmigiani, G.4    Vogelstein, B.5
  • 46
    • 84055211870 scopus 로고    scopus 로고
    • Lysine demethylases inhibitors
    • Suzuki T, Miyata N. Lysine demethylases inhibitors. J Med Chem. 2011;54(24):8236-8250.
    • (2011) J Med Chem , vol.54 , Issue.24 , pp. 8236-8250
    • Suzuki, T.1    Miyata, N.2
  • 47
    • 84903155987 scopus 로고    scopus 로고
    • Histone lysine demethylase (KDM) subfamily 4: Structures, functions and therapeutic potential
    • Labbe RM, Holowatyj A, Yang ZQ. Histone lysine demethylase (KDM) subfamily 4: structures, functions and therapeutic potential. Am J Transl Res. 2013;6(1):1-15.
    • (2013) Am J Transl Res , vol.6 , Issue.1 , pp. 1-15
    • Labbe, R.M.1    Holowatyj, A.2    Yang, Z.Q.3
  • 48
    • 84889595831 scopus 로고    scopus 로고
    • A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
    • Wang L, et al. A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth. Nat Commun. 2013;4:2035.
    • (2013) Nat Commun , vol.4 , pp. 2035
    • Wang, L.1
  • 49
    • 35948961118 scopus 로고    scopus 로고
    • Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
    • Zhao B, et al. Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev. 2007;21(21):2747-2761.
    • (2007) Genes Dev , vol.21 , Issue.21 , pp. 2747-2761
    • Zhao, B.1
  • 50
    • 84930591340 scopus 로고    scopus 로고
    • ERG activates the YAP1 transcriptional program and induces the development of age-related prostate tumors
    • Nguyen LT, et al. ERG activates the YAP1 transcriptional program and induces the development of age-related prostate tumors. Cancer Cell. 2015;27(6):797-808.
    • (2015) Cancer Cell , vol.27 , Issue.6 , pp. 797-808
    • Nguyen, L.T.1
  • 51
    • 84923183206 scopus 로고    scopus 로고
    • The emerging roles of YAP and TAZ in cancer
    • Moroishi T, Hansen CG, Guan KL. The emerging roles of YAP and TAZ in cancer. Nat Rev Cancer. 2015;15(2):73-79.
    • (2015) Nat Rev Cancer , vol.15 , Issue.2 , pp. 73-79
    • Moroishi, T.1    Hansen, C.G.2    Guan, K.L.3
  • 52
    • 84893576085 scopus 로고    scopus 로고
    • A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer
    • Jiao S, et al. A peptide mimicking VGLL4 function acts as a YAP antagonist therapy against gastric cancer. Cancer Cell. 2014;25(2):166-180.
    • (2014) Cancer Cell , vol.25 , Issue.2 , pp. 166-180
    • Jiao, S.1
  • 53
    • 27344451557 scopus 로고    scopus 로고
    • Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer
    • Tomlins SA, et al. Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer. Science. 2005;310(5748):644-648.
    • (2005) Science , vol.310 , Issue.5748 , pp. 644-648
    • Tomlins, S.A.1
  • 54
    • 84930573987 scopus 로고    scopus 로고
    • The TGF-β signaling regulator PMEPA1 suppresses prostate cancer metastases to bone
    • Fournier PGJ, et al. The TGF-β signaling regulator PMEPA1 suppresses prostate cancer metastases to bone. Cancer Cell. 2015;27(6):809-821.
    • (2015) Cancer Cell , vol.27 , Issue.6 , pp. 809-821
    • Fournier, P.G.J.1
  • 55
    • 73649085521 scopus 로고    scopus 로고
    • TMEPAI, a transmembrane TGF-β-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling
    • Watanabe Y, et al. TMEPAI, a transmembrane TGF-β-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling. Mol Cell. 2010;37(1):123-134.
    • (2010) Mol Cell , vol.37 , Issue.1 , pp. 123-134
    • Watanabe, Y.1
  • 56
    • 0036899998 scopus 로고    scopus 로고
    • High expression of the Met receptor in prostate cancer metastasis to bone
    • Knudsen BS, et al. High expression of the Met receptor in prostate cancer metastasis to bone. Urology. 2002;60(6):1113-1117.
    • (2002) Urology , vol.60 , Issue.6 , pp. 1113-1117
    • Knudsen, B.S.1
  • 57
    • 84860340496 scopus 로고    scopus 로고
    • Castration resistant prostate cancer is associated with increased blood vessel stabilization and elevated levels of VEGF and Ang-2
    • Tomic TT, Gustavsson H, Wang W, Jennbacken K, Welen K, Damber JE. Castration resistant prostate cancer is associated with increased blood vessel stabilization and elevated levels of VEGF and Ang-2. Prostate. 2012;72(7):705-712.
    • (2012) Prostate , vol.72 , Issue.7 , pp. 705-712
    • Tomic, T.T.1    Gustavsson, H.2    Wang, W.3    Jennbacken, K.4    Welen, K.5    Damber, J.E.6
  • 58
    • 84863115795 scopus 로고    scopus 로고
    • The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells
    • Kim TD, Shin S, Berry WL, Oh S, Janknecht R. The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells. J Cell Biochem. 2012;113(4):1368-1376.
    • (2012) J Cell Biochem , vol.113 , Issue.4 , pp. 1368-1376
    • Kim, T.D.1    Shin, S.2    Berry, W.L.3    Oh, S.4    Janknecht, R.5
  • 59
    • 84867808958 scopus 로고    scopus 로고
    • Oncogenic features of the JMJD2A histone demethylase in breast cancer
    • Berry WL, Shin S, Lightfoot SA, Janknecht R. Oncogenic features of the JMJD2A histone demethylase in breast cancer. Int J Oncol. 2012;41(5):1701-1706.
    • (2012) Int J Oncol , vol.41 , Issue.5 , pp. 1701-1706
    • Berry, W.L.1    Shin, S.2    Lightfoot, S.A.3    Janknecht, R.4
  • 60
    • 84870463217 scopus 로고    scopus 로고
    • JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5
    • Mallette FA, Richard S. JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5. Cell Rep. 2012;2(5):1233-1243.
    • (2012) Cell Rep , vol.2 , Issue.5 , pp. 1233-1243
    • Mallette, F.A.1    Richard, S.2
  • 61
    • 0037421959 scopus 로고    scopus 로고
    • Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1)
    • Janknecht R. Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1). Oncogene. 2003;22(5):746-755.
    • (2003) Oncogene , vol.22 , Issue.5 , pp. 746-755
    • Janknecht, R.1
  • 62
    • 0033830524 scopus 로고    scopus 로고
    • Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300
    • Papoutsopoulou S, Janknecht R. Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300. Mol Cell Biol. 2000;20(19):7300-7310.
    • (2000) Mol Cell Biol , vol.20 , Issue.19 , pp. 7300-7310
    • Papoutsopoulou, S.1    Janknecht, R.2
  • 63
    • 0042971584 scopus 로고    scopus 로고
    • Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu
    • Goel A, Janknecht R. Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu. Mol Cell Biol. 2003;23(17):6243-6254.
    • (2003) Mol Cell Biol , vol.23 , Issue.17 , pp. 6243-6254
    • Goel, A.1    Janknecht, R.2
  • 64
    • 84894451091 scopus 로고    scopus 로고
    • Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase
    • Berry WL, Kim TD, Janknecht R. Stimulation of beta-catenin and colon cancer cell growth by the KDM4B histone demethylase. Int J Oncol. 2014;44(4):1341-1348.
    • (2014) Int J Oncol , vol.44 , Issue.4 , pp. 1341-1348
    • Berry, W.L.1    Kim, T.D.2    Janknecht, R.3
  • 66
    • 0037044832 scopus 로고    scopus 로고
    • Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A
    • Wu J, Janknecht R. Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. J Biol Chem. 2002;277(45):42669-42679.
    • (2002) J Biol Chem , vol.277 , Issue.45 , pp. 42669-42679
    • Wu, J.1    Janknecht, R.2
  • 67
    • 33847246805 scopus 로고    scopus 로고
    • Oncomine 3.0: Genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles
    • Rhodes DR, et al. Oncomine 3.0: genes, pathways, and networks in a collection of 18,000 cancer gene expression profiles. Neoplasia. 2007;9(2):166-180.
    • (2007) Neoplasia , vol.9 , Issue.2 , pp. 166-180
    • Rhodes, D.R.1
  • 68
    • 84882728530 scopus 로고    scopus 로고
    • 14-3-3 proteins modulate the ETS transcription factor ETV1 in prostate cancer
    • Oh S, Shin S, Lightfoot SA, Janknecht R. 14-3-3 proteins modulate the ETS transcription factor ETV1 in prostate cancer. Cancer Res. 2013;73(16):5110-5119.
    • (2013) Cancer Res , vol.73 , Issue.16 , pp. 5110-5119
    • Oh, S.1    Shin, S.2    Lightfoot, S.A.3    Janknecht, R.4
  • 69
    • 84859725611 scopus 로고    scopus 로고
    • Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D
    • Kim TD, Oh S, Shin S, Janknecht R. Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. PLoS One. 2012;7(4):e34618.
    • (2012) PLoS One , vol.7 , Issue.4 , pp. e34618
    • Kim, T.D.1    Oh, S.2    Shin, S.3    Janknecht, R.4
  • 70
    • 13044250465 scopus 로고    scopus 로고
    • Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems
    • Podsypanina K, et al. Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems. Proc Natl Acad Sci U S A. 1999;96(4):1563-1568.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.4 , pp. 1563-1568
    • Podsypanina, K.1
  • 71
    • 84863611733 scopus 로고    scopus 로고
    • Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis
    • DiTacchio L, Bowles J, Shin S, Lim DS, Koopman P, Janknecht R. Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis. J Biol Chem. 2012;287(28):23657-23666.
    • (2012) J Biol Chem , vol.287 , Issue.28 , pp. 23657-23666
    • DiTacchio, L.1    Bowles, J.2    Shin, S.3    Lim, D.S.4    Koopman, P.5    Janknecht, R.6
  • 72
    • 2442607847 scopus 로고    scopus 로고
    • Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu
    • Goel A, Janknecht R. Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu. J Biol Chem. 2004;279(15):14909-14916.
    • (2004) J Biol Chem , vol.279 , Issue.15 , pp. 14909-14916
    • Goel, A.1    Janknecht, R.2
  • 73
    • 0345549479 scopus 로고    scopus 로고
    • Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor
    • Goueli BS, Janknecht R. Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor. Oncogene. 2003;22(39):8042-8047.
    • (2003) Oncogene , vol.22 , Issue.39 , pp. 8042-8047
    • Goueli, B.S.1    Janknecht, R.2


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