Gene expression profiling identifies cell proliferation and inflammation as the predominant pathways regulated by Aryl hydrocarbon receptor in primary human fetal lung cells exposed to hyperoxia

Toxicological Sciences

Volumn 152, Issue 1, 2016, Pages 155-168

  Shivanna, Binoy ^a   Maity, Suman ^a   Zhang, Shaojie ^a   Patel, Ananddeep ^a   Jiang, Weiwu ^a   Wang, Lihua ^a   Welty, Stephen E ^a   Belmont, John ^a   Coarfa, Cristian ^a   Moorthy, Bhagavatula ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Aryl hydrocarbon receptor; Fetal human lung cells; Gene expression profile; Hyperoxia; Organ development

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; CYTOKINE; TRANSCRIPTOME; AHR PROTEIN, HUMAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL CYCLE; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FETUS; FETUS LUNG; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GENE SILENCING; HUMAN; HUMAN CELL; HYPEROXIA; IMMUNE RESPONSE; IMMUNOREGULATION; INFLAMMATION; LUNG ALVEOLUS CELL; LUNG DYSPLASIA; LUNG INJURY; MICROARRAY ANALYSIS; MICROARRAY KIT; MOUSE; MOUSE MODEL; NEWBORN; NONHUMAN; ORGANOGENESIS; PULMONARY MICROVASCULAR ENDOTHELIAL CELL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRESS; UPREGULATION; BIOLOGY; CELL CULTURE; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORK; GENETIC DATABASE; GENETIC TRANSFECTION; GENETICS; LUNG; METABOLISM; PATHOLOGY; PNEUMONIA; PROCEDURES; RNA INTERFERENCE; TIME FACTOR;

BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BRONCHOPULMONARY DYSPLASIA; CELL PROLIFERATION; CELLS, CULTURED; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE REGULATORY NETWORKS; HUMANS; HYPEROXIA; LUNG; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PNEUMONIA; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ARYL HYDROCARBON; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSCRIPTOME; TRANSFECTION;

EID: 84991377624     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfw071     Document Type: Article

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