Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB

Toxicology and Applied Pharmacology

Volumn 286, Issue 2, 2015, Pages 92-101

  Zhang, Shaojie ^a   Patel, Ananddeep ^a   Chu, Chun ^a   Jiang, Weiwu ^a   Wang, Lihua ^a   Welty, Stephen E ^a   Moorthy, Bhagavatula ^a   Shivanna, Binoy ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Antioxidant enzymes; Aryl hydrocarbon receptor; Fetal human pulmonary microvascular endothelial cells; Hyperoxic injury; Oxidant stress; RelB

Indexed keywords

ANTIOXIDANT; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A; CYTOCHROME P450 1A1; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NITRATE REDUCTASE (NADPH); OXIDOREDUCTASE; QUINONE DERIVATIVE; REACTIVE OXYGEN METABOLITE; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELB; AHR PROTEIN, HUMAN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; RELB PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL CULTURE; CELL DEATH; CELL PROTECTION; DISEASE PREDISPOSITION; FETUS; HUMAN; HUMAN CELL; HYPEROXIA; LUNG ALVEOLUS CELL; MACROPHAGE; OXIDATIVE STRESS; PROTEIN EXPRESSION; SUPERNATANT; ADULT; APOPTOSIS; CAPILLARY; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; ENDOTHELIUM CELL; FEMALE; GENETICS; INFLAMMATION; LUNG CIRCULATION; METABOLISM; NECROSIS; PATHOLOGY; PREGNANCY;

ANIMALIA; MUS;

ADULT; ANTIOXIDANTS; APOPTOSIS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CAPILLARIES; CELL PROLIFERATION; CELL SURVIVAL; ENDOTHELIAL CELLS; FEMALE; HUMANS; HYPEROXIA; INFLAMMATION; NECROSIS; OXIDATIVE STRESS; PREGNANCY; PULMONARY CIRCULATION; REACTIVE OXYGEN SPECIES; RECEPTORS, ARYL HYDROCARBON; RNA, SMALL INTERFERING; TRANSCRIPTION FACTOR RELB;

EID: 84930274964     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2015.03.023     Document Type: Article

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