메뉴 건너뛰기




Volumn 12, Issue , 2011, Pages

Placenta growth factor and vascular endothelial growth factor B expression in the hypoxic lung

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PLACENTAL GROWTH FACTOR; VASCULOTROPIN A; VASCULOTROPIN B; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; FLT1 PROTEIN, RAT; PLACENTA PROTEIN; VASCULAR ENDOTHELIAL GROWTH FACTOR A, RAT;

EID: 78951482247     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/1465-9921-12-17     Document Type: Article
Times cited : (28)

References (63)
  • 1
    • 0028143329 scopus 로고
    • Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two
    • MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part two. Am J Respir Crit Care Med 1994, 150(4):1158-68.
    • (1994) Am J Respir Crit Care Med , vol.150 , Issue.4 , pp. 1158-1168
    • MacNee, W.1
  • 2
    • 0027930046 scopus 로고
    • Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One
    • MacNee W. Pathophysiology of cor pulmonale in chronic obstructive pulmonary disease. Part One. Am J Respir Crit Care Med 1994, 150(3):833-52.
    • (1994) Am J Respir Crit Care Med , vol.150 , Issue.3 , pp. 833-852
    • MacNee, W.1
  • 3
    • 4143118866 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension
    • 10.1016/j.mvr.2004.06.001, 15313118
    • Mandegar M, et al. Cellular and molecular mechanisms of pulmonary vascular remodeling: role in the development of pulmonary hypertension. Microvasc Res 2004, 68(2):75-103. 10.1016/j.mvr.2004.06.001, 15313118.
    • (2004) Microvasc Res , vol.68 , Issue.2 , pp. 75-103
    • Mandegar, M.1
  • 4
    • 22744455284 scopus 로고    scopus 로고
    • Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation
    • 10.1161/01.RES.0000174287.17953.83, 15961717
    • Hyvelin JM, et al. Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation. Circ Res 2005, 97(2):185-91. 10.1161/01.RES.0000174287.17953.83, 15961717.
    • (2005) Circ Res , vol.97 , Issue.2 , pp. 185-191
    • Hyvelin, J.M.1
  • 5
    • 0037440743 scopus 로고    scopus 로고
    • Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation
    • 10.1113/jphysiol.2002.030676, 2342608, 12562951
    • Howell K, Preston RJ, McLoughlin P. Chronic hypoxia causes angiogenesis in addition to remodelling in the adult rat pulmonary circulation. J Physiol 2003, 547(Pt 1):133-45. 10.1113/jphysiol.2002.030676, 2342608, 12562951.
    • (2003) J Physiol , vol.547 , Issue.PART 1 , pp. 133-145
    • Howell, K.1    Preston, R.J.2    McLoughlin, P.3
  • 6
    • 0036723641 scopus 로고    scopus 로고
    • Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure
    • Le Cras TD, et al. Treatment of newborn rats with a VEGF receptor inhibitor causes pulmonary hypertension and abnormal lung structure. Am J Physiol Lung Cell Mol Physiol 2002, 283(3):L555-62.
    • (2002) Am J Physiol Lung Cell Mol Physiol , vol.283 , Issue.3
    • Le Cras, T.D.1
  • 7
    • 34147189502 scopus 로고    scopus 로고
    • Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats
    • 10.1161/01.RES.0000261658.12024.18, 17332430
    • Oka M, et al. Rho kinase-mediated vasoconstriction is important in severe occlusive pulmonary arterial hypertension in rats. Circ Res 2007, 100(6):923-9. 10.1161/01.RES.0000261658.12024.18, 17332430.
    • (2007) Circ Res , vol.100 , Issue.6 , pp. 923-929
    • Oka, M.1
  • 8
    • 0036245561 scopus 로고    scopus 로고
    • Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension
    • 10.1097/00003246-200205001-00013, 12004244
    • Voelkel NF, et al. Janus face of vascular endothelial growth factor: the obligatory survival factor for lung vascular endothelium controls precapillary artery remodeling in severe pulmonary hypertension. Crit Care Med 2002, 30(5 Suppl):S251-6. 10.1097/00003246-200205001-00013, 12004244.
    • (2002) Crit Care Med , vol.30 , Issue.5 SUPPL
    • Voelkel, N.F.1
  • 9
    • 0034533016 scopus 로고    scopus 로고
    • Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats
    • Partovian C, et al. Adenovirus-mediated lung vascular endothelial growth factor overexpression protects against hypoxic pulmonary hypertension in rats. Am J Respir Cell Mol Biol 2000, 23(6):762-71.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , Issue.6 , pp. 762-771
    • Partovian, C.1
  • 10
    • 30944440262 scopus 로고    scopus 로고
    • Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF)
    • 10.1111/j.1582-4934.2005.tb00379.x, 16364190
    • Byrne AM, Bouchier-Hayes DJ, Harmey JH. Angiogenic and cell survival functions of vascular endothelial growth factor (VEGF). J Cell Mol Med 2005, 9(4):777-94. 10.1111/j.1582-4934.2005.tb00379.x, 16364190.
    • (2005) J Cell Mol Med , vol.9 , Issue.4 , pp. 777-794
    • Byrne, A.M.1    Bouchier-Hayes, D.J.2    Harmey, J.H.3
  • 11
    • 34250370123 scopus 로고    scopus 로고
    • Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting
    • 10.1084/jem.20062642, 2118625, 17535974
    • Wirzenius M, et al. Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting. J Exp Med 2007, 204(6):1431-40. 10.1084/jem.20062642, 2118625, 17535974.
    • (2007) J Exp Med , vol.204 , Issue.6 , pp. 1431-1440
    • Wirzenius, M.1
  • 12
    • 0037455583 scopus 로고    scopus 로고
    • Pseudocowpox virus encodes a homolog of vascular endothelial growth factor
    • 10.1006/viro.2002.1750, 12573575
    • Ueda N, et al. Pseudocowpox virus encodes a homolog of vascular endothelial growth factor. Virology 2003, 305(2):298-309. 10.1006/viro.2002.1750, 12573575.
    • (2003) Virology , vol.305 , Issue.2 , pp. 298-309
    • Ueda, N.1
  • 13
    • 34347332447 scopus 로고    scopus 로고
    • Neuropilins in physiological and pathological angiogenesis
    • 10.1002/path.2182, 17503412
    • Staton CA, et al. Neuropilins in physiological and pathological angiogenesis. J Pathol 2007, 212(3):237-48. 10.1002/path.2182, 17503412.
    • (2007) J Pathol , vol.212 , Issue.3 , pp. 237-248
    • Staton, C.A.1
  • 14
    • 54549123309 scopus 로고    scopus 로고
    • VEGF-A splicing: the key to anti-angiogenic therapeutics?
    • 10.1038/nrc2505, 2613352, 18923433
    • Harper SJ, Bates DO. VEGF-A splicing: the key to anti-angiogenic therapeutics?. Nat Rev Cancer 2008, 8(11):880-7. 10.1038/nrc2505, 2613352, 18923433.
    • (2008) Nat Rev Cancer , vol.8 , Issue.11 , pp. 880-887
    • Harper, S.J.1    Bates, D.O.2
  • 15
    • 77952752660 scopus 로고    scopus 로고
    • VEGF in the lung: a role for novel isoforms
    • 10.1152/ajplung.00353.2009, 2886605, 20228180
    • Varet J, et al. VEGF in the lung: a role for novel isoforms. Am J Physiol Lung Cell Mol Physiol 2010, 298(6):L768-74. 10.1152/ajplung.00353.2009, 2886605, 20228180.
    • (2010) Am J Physiol Lung Cell Mol Physiol , vol.298 , Issue.6
    • Varet, J.1
  • 16
    • 0028134936 scopus 로고
    • Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR
    • Park JE, et al. Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR. J Biol Chem 1994, 269(41):25646-54.
    • (1994) J Biol Chem , vol.269 , Issue.41 , pp. 25646-25654
    • Park, J.E.1
  • 17
    • 0028956308 scopus 로고
    • Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer
    • 10.1074/jbc.270.13.7717, 7706320
    • DiSalvo J, et al. Purification and characterization of a naturally occurring vascular endothelial growth factor.placenta growth factor heterodimer. J Biol Chem 1995, 270(13):7717-23. 10.1074/jbc.270.13.7717, 7706320.
    • (1995) J Biol Chem , vol.270 , Issue.13 , pp. 7717-7723
    • DiSalvo, J.1
  • 18
    • 17044441694 scopus 로고    scopus 로고
    • Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers
    • 10.1016/S1535-6108(02)00028-4, 12086892
    • Eriksson A, et al. Placenta growth factor-1 antagonizes VEGF-induced angiogenesis and tumor growth by the formation of functionally inactive PlGF-1/VEGF heterodimers. Cancer Cell 2002, 1(1):99-108. 10.1016/S1535-6108(02)00028-4, 12086892.
    • (2002) Cancer Cell , vol.1 , Issue.1 , pp. 99-108
    • Eriksson, A.1
  • 19
    • 10744226927 scopus 로고    scopus 로고
    • Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema
    • 10.1164/rccm.200306-774OC, 14644931
    • Tsao PN, et al. Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema. Am J Respir Crit Care Med 2004, 169(4):505-11. 10.1164/rccm.200306-774OC, 14644931.
    • (2004) Am J Respir Crit Care Med , vol.169 , Issue.4 , pp. 505-511
    • Tsao, P.N.1
  • 20
    • 73949100826 scopus 로고    scopus 로고
    • Prevention of elastase-induced emphysema in placenta growth factor knock-out mice
    • 10.1186/1465-9921-10-115, 2789728, 19930612
    • Cheng SL, et al. Prevention of elastase-induced emphysema in placenta growth factor knock-out mice. Respir Res 2009, 10:115. 10.1186/1465-9921-10-115, 2789728, 19930612.
    • (2009) Respir Res , vol.10 , pp. 115
    • Cheng, S.L.1
  • 21
    • 45149124341 scopus 로고    scopus 로고
    • Increased expression of placenta growth factor in COPD
    • 10.1136/thx.2007.087155, 2571977, 18202163
    • Cheng SL, et al. Increased expression of placenta growth factor in COPD. Thorax 2008, 63(6):500-6. 10.1136/thx.2007.087155, 2571977, 18202163.
    • (2008) Thorax , vol.63 , Issue.6 , pp. 500-506
    • Cheng, S.L.1
  • 22
    • 0034099007 scopus 로고    scopus 로고
    • Chronic hypercapnia inhibits hypoxic pulmonary vascular remodeling
    • Ooi H, et al. Chronic hypercapnia inhibits hypoxic pulmonary vascular remodeling. Am J Physiol Heart Circ Physiol 2000, 278(2):H331-8.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278 , Issue.2
    • Ooi, H.1
  • 23
    • 0025946841 scopus 로고
    • Ultrastructural appearances of pulmonary capillaries at high transmural pressures
    • Tsukimoto K, et al. Ultrastructural appearances of pulmonary capillaries at high transmural pressures. J Appl Physiol 1991, 71(2):573-82.
    • (1991) J Appl Physiol , vol.71 , Issue.2 , pp. 573-582
    • Tsukimoto, K.1
  • 24
    • 0027760939 scopus 로고
    • Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology
    • Bolender RP, Hyde DM, Dehoff RT. Lung morphometry: a new generation of tools and experiments for organ, tissue, cell, and molecular biology. Am J Physiol 1993, 265(6 Pt 1):L521-48.
    • (1993) Am J Physiol , vol.265 , Issue.6 PART 1
    • Bolender, R.P.1    Hyde, D.M.2    Dehoff, R.T.3
  • 25
    • 76149084817 scopus 로고    scopus 로고
    • An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure
    • 10.1164/rccm.200809-1522ST, 20130146
    • Hsia CC, et al. An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med 2010, 181(4):394-418. 10.1164/rccm.200809-1522ST, 20130146.
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.4 , pp. 394-418
    • Hsia, C.C.1
  • 26
    • 0033045425 scopus 로고    scopus 로고
    • The efficiency of systematic sampling in stereology--reconsidered
    • 10.1046/j.1365-2818.1999.00457.x, 10348656
    • Gundersen HJ, et al. The efficiency of systematic sampling in stereology--reconsidered. J Microsc 1999, 193(Pt 3):199-211. 10.1046/j.1365-2818.1999.00457.x, 10348656.
    • (1999) J Microsc , vol.193 , Issue.PART 3 , pp. 199-211
    • Gundersen, H.J.1
  • 27
    • 0036849495 scopus 로고    scopus 로고
    • Combined confocal microscopy and stereology: a highly efficient and unbiased approach to quantitative structural measurement in tissues
    • 10.1113/eph8702477, 12530405
    • Howell K, Hopkins N, McLoughlin P. Combined confocal microscopy and stereology: a highly efficient and unbiased approach to quantitative structural measurement in tissues. Exp Physiol 2002, 87(6):747-56. 10.1113/eph8702477, 12530405.
    • (2002) Exp Physiol , vol.87 , Issue.6 , pp. 747-756
    • Howell, K.1    Hopkins, N.2    McLoughlin, P.3
  • 28
    • 67049099308 scopus 로고    scopus 로고
    • L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension
    • 10.1152/ajplung.90327.2008, 19346433
    • Howell K, et al. L-Arginine promotes angiogenesis in the chronically hypoxic lung: a novel mechanism ameliorating pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2009, 296(6):L1042-50. 10.1152/ajplung.90327.2008, 19346433.
    • (2009) Am J Physiol Lung Cell Mol Physiol , vol.296 , Issue.6
    • Howell, K.1
  • 29
    • 0032887554 scopus 로고    scopus 로고
    • Enhanced expression of inducible nitric oxide synthase without vasodilator effect in chronically infected lungs
    • Cadogan E, et al. Enhanced expression of inducible nitric oxide synthase without vasodilator effect in chronically infected lungs. Am J Physiol 1999, 277(3 Pt 1):L616-27.
    • (1999) Am J Physiol , vol.277 , Issue.3 PART 1
    • Cadogan, E.1
  • 30
    • 52149085463 scopus 로고    scopus 로고
    • Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension
    • 10.1152/ajplung.00358.2007, 18469115
    • Costello CM, et al. Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol 2008, 295(2):L272-84. 10.1152/ajplung.00358.2007, 18469115.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295 , Issue.2
    • Costello, C.M.1
  • 32
    • 0020358356 scopus 로고
    • Failure to show decrease in small pulmonary blood vessels in rats with experimental pulmonary hypertension
    • 10.1136/thx.37.12.927, 459460, 6820578
    • Kay JM, Suyama KL, Keane PM. Failure to show decrease in small pulmonary blood vessels in rats with experimental pulmonary hypertension. Thorax 1982, 37(12):927-30. 10.1136/thx.37.12.927, 459460, 6820578.
    • (1982) Thorax , vol.37 , Issue.12 , pp. 927-930
    • Kay, J.M.1    Suyama, K.L.2    Keane, P.M.3
  • 33
    • 0029083303 scopus 로고
    • Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension
    • Mehta S, et al. Short-term pulmonary vasodilation with L-arginine in pulmonary hypertension. Circulation 1995, 92(6):1539-45.
    • (1995) Circulation , vol.92 , Issue.6 , pp. 1539-1545
    • Mehta, S.1
  • 34
    • 0030840893 scopus 로고    scopus 로고
    • Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats
    • Mitani Y, Maruyama K, Sakurai M. Prolonged administration of L-arginine ameliorates chronic pulmonary hypertension and pulmonary vascular remodeling in rats. Circulation 1997, 96(2):689-97.
    • (1997) Circulation , vol.96 , Issue.2 , pp. 689-697
    • Mitani, Y.1    Maruyama, K.2    Sakurai, M.3
  • 35
    • 15944403568 scopus 로고    scopus 로고
    • Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension
    • 10.1164/rccm.200405-637OC, 15563635
    • Nagaoka T, et al. Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. Am J Respir Crit Care Med 2005, 171(5):494-9. 10.1164/rccm.200405-637OC, 15563635.
    • (2005) Am J Respir Crit Care Med , vol.171 , Issue.5 , pp. 494-499
    • Nagaoka, T.1
  • 36
    • 0032429293 scopus 로고    scopus 로고
    • Heart and lung VEGF mRNA expression in rats with monocrotaline- or hypoxia-induced pulmonary hypertension
    • Partovian C, et al. Heart and lung VEGF mRNA expression in rats with monocrotaline- or hypoxia-induced pulmonary hypertension. Am J Physiol 1998, 275(6 Pt 2):H1948-56.
    • (1998) Am J Physiol , vol.275 , Issue.6 PART 2
    • Partovian, C.1
  • 37
    • 0018487516 scopus 로고
    • Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features
    • Rabinovitch M, et al. Rat pulmonary circulation after chronic hypoxia: hemodynamic and structural features. Am J Physiol 1979, 236(6):H818-27.
    • (1979) Am J Physiol , vol.236 , Issue.6
    • Rabinovitch, M.1
  • 38
    • 0141526110 scopus 로고    scopus 로고
    • Lung overexpression of angiostatin aggravates pulmonary hypertension in chronically hypoxic mice
    • 10.1165/rcmb.2002-0120OC, 12714372
    • Pascaud MA, et al. Lung overexpression of angiostatin aggravates pulmonary hypertension in chronically hypoxic mice. Am J Respir Cell Mol Biol 2003, 29(4):449-57. 10.1165/rcmb.2002-0120OC, 12714372.
    • (2003) Am J Respir Cell Mol Biol , vol.29 , Issue.4 , pp. 449-457
    • Pascaud, M.A.1
  • 39
    • 33845443200 scopus 로고    scopus 로고
    • Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2
    • 10.1152/ajplung.00168.2006, 16891392
    • Yamaji-Kegan K, et al. Hypoxia-induced mitogenic factor has proangiogenic and proinflammatory effects in the lung via VEGF and VEGF receptor-2. Am J Physiol Lung Cell Mol Physiol 2006, 291(6):L1159-68. 10.1152/ajplung.00168.2006, 16891392.
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291 , Issue.6
    • Yamaji-Kegan, K.1
  • 40
    • 66949146558 scopus 로고    scopus 로고
    • IL-4 is proangiogenic in the lung under hypoxic conditions
    • 10.4049/jimmunol.0713347, 19380795
    • Yamaji-Kegan K, et al. IL-4 is proangiogenic in the lung under hypoxic conditions. J Immunol 2009, 182(9):5469-76. 10.4049/jimmunol.0713347, 19380795.
    • (2009) J Immunol , vol.182 , Issue.9 , pp. 5469-5476
    • Yamaji-Kegan, K.1
  • 41
    • 0032446730 scopus 로고    scopus 로고
    • Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor-B in lung parenchyma
    • Berg JT, et al. Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor-B in lung parenchyma. Am J Respir Crit Care Med 1998, 158(6):1920-8.
    • (1998) Am J Respir Crit Care Med , vol.158 , Issue.6 , pp. 1920-1928
    • Berg, J.T.1
  • 42
    • 30144435869 scopus 로고    scopus 로고
    • Role of angiopoietin-1 in experimental and human pulmonary arterial hypertension
    • 10.1378/chest.128.6_suppl.633S, 16373885
    • Kugathasan L, et al. Role of angiopoietin-1 in experimental and human pulmonary arterial hypertension. Chest 2005, 128(6 Suppl):633S-642S. 10.1378/chest.128.6_suppl.633S, 16373885.
    • (2005) Chest , vol.128 , Issue.6 SUPPL
    • Kugathasan, L.1
  • 43
    • 0344431290 scopus 로고    scopus 로고
    • Vascular remodeling and growth factor gene expression in the rat lung during hypoxia
    • 10.1016/S0034-5687(97)00102-3, 9574871
    • Pfeifer M, et al. Vascular remodeling and growth factor gene expression in the rat lung during hypoxia. Respir Physiol 1998, 111(2):201-12. 10.1016/S0034-5687(97)00102-3, 9574871.
    • (1998) Respir Physiol , vol.111 , Issue.2 , pp. 201-212
    • Pfeifer, M.1
  • 44
    • 0032090254 scopus 로고    scopus 로고
    • Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension
    • Christou H, et al. Increased vascular endothelial growth factor production in the lungs of rats with hypoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol 1998, 18(6):768-76.
    • (1998) Am J Respir Cell Mol Biol , vol.18 , Issue.6 , pp. 768-776
    • Christou, H.1
  • 45
    • 0028940664 scopus 로고
    • Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide
    • 10.1172/JCI117858, 295709, 7706486
    • Tuder RM, Flook BE, Voelkel NF. Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide. J Clin Invest 1995, 95(4):1798-807. 10.1172/JCI117858, 295709, 7706486.
    • (1995) J Clin Invest , vol.95 , Issue.4 , pp. 1798-1807
    • Tuder, R.M.1    Flook, B.E.2    Voelkel, N.F.3
  • 46
    • 41349091229 scopus 로고    scopus 로고
    • Downregulation of angiopoietin-1 and Tie2 in chronic hypoxic pulmonary hypertension
    • 10.1159/000112432, 18073453
    • Yamamoto A, et al. Downregulation of angiopoietin-1 and Tie2 in chronic hypoxic pulmonary hypertension. Respiration 2008, 75(3):328-38. 10.1159/000112432, 18073453.
    • (2008) Respiration , vol.75 , Issue.3 , pp. 328-338
    • Yamamoto, A.1
  • 47
    • 37249017976 scopus 로고    scopus 로고
    • Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats
    • 10.1089/ham.2007.1031, 18081507
    • Engebretsen BJ, et al. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats. High Alt Med Biol 2007, 8(4):312-21. 10.1089/ham.2007.1031, 18081507.
    • (2007) High Alt Med Biol , vol.8 , Issue.4 , pp. 312-321
    • Engebretsen, B.J.1
  • 48
    • 13844272191 scopus 로고    scopus 로고
    • Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta
    • 10.1016/j.placenta.2004.05.004, 15708122
    • Li H, et al. Hypoxia-induced increase in soluble Flt-1 production correlates with enhanced oxidative stress in trophoblast cells from the human placenta. Placenta 2005, 26(2-3):210-7. 10.1016/j.placenta.2004.05.004, 15708122.
    • (2005) Placenta , vol.26 , Issue.2-3 , pp. 210-217
    • Li, H.1
  • 49
    • 38349138809 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and nitric oxide production in response to hypoxia in the choroid plexus in neonatal brain
    • 10.1111/j.1750-3639.2007.00104.x, 17924979
    • Sivakumar V, et al. Vascular endothelial growth factor and nitric oxide production in response to hypoxia in the choroid plexus in neonatal brain. Brain Pathol 2008, 18(1):71-85. 10.1111/j.1750-3639.2007.00104.x, 17924979.
    • (2008) Brain Pathol , vol.18 , Issue.1 , pp. 71-85
    • Sivakumar, V.1
  • 50
    • 14444283112 scopus 로고    scopus 로고
    • Rat brain VEGF expression in alveolar hypoxia: possible role in high-altitude cerebral edema
    • Xu F, Severinghaus JW. Rat brain VEGF expression in alveolar hypoxia: possible role in high-altitude cerebral edema. J Appl Physiol 1998, 85(1):53-7.
    • (1998) J Appl Physiol , vol.85 , Issue.1 , pp. 53-57
    • Xu, F.1    Severinghaus, J.W.2
  • 51
    • 37549021801 scopus 로고    scopus 로고
    • Evaluation of hypoxia-mediated growth factors in a novel bladder cancer animal model
    • Fechner G, et al. Evaluation of hypoxia-mediated growth factors in a novel bladder cancer animal model. Anticancer Res 2007, 27(6B):4225-31.
    • (2007) Anticancer Res , vol.27 , Issue.6 B , pp. 4225-4231
    • Fechner, G.1
  • 52
    • 38149060090 scopus 로고    scopus 로고
    • Detection and characterization of vascular endothelial growth factors and their receptors in a series of angiosarcomas
    • 10.1002/jso.20766, 18041747
    • Itakura E, et al. Detection and characterization of vascular endothelial growth factors and their receptors in a series of angiosarcomas. J Surg Oncol 2008, 97(1):74-81. 10.1002/jso.20766, 18041747.
    • (2008) J Surg Oncol , vol.97 , Issue.1 , pp. 74-81
    • Itakura, E.1
  • 53
    • 0033071015 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor mRNA expression in patients with chronic hepatitis C and hepatocellular carcinoma
    • Shimoda K, et al. Vascular endothelial growth factor/vascular permeability factor mRNA expression in patients with chronic hepatitis C and hepatocellular carcinoma. Int J Oncol 1999, 14(2):353-9.
    • (1999) Int J Oncol , vol.14 , Issue.2 , pp. 353-359
    • Shimoda, K.1
  • 54
    • 0032499677 scopus 로고    scopus 로고
    • Microvascular and tissue oxygen gradients in the rat mesentery
    • 10.1073/pnas.95.12.6590, 22570, 9618456
    • Tsai AG, et al. Microvascular and tissue oxygen gradients in the rat mesentery. Proc Natl Acad Sci USA 1998, 95(12):6590-5. 10.1073/pnas.95.12.6590, 22570, 9618456.
    • (1998) Proc Natl Acad Sci USA , vol.95 , Issue.12 , pp. 6590-6595
    • Tsai, A.G.1
  • 55
    • 34447619345 scopus 로고    scopus 로고
    • Evidence that renal arterial-venous oxygen shunting contributes to dynamic regulation of renal oxygenation
    • 10.1152/ajprenal.00436.2006, 17327497
    • Leong CL, et al. Evidence that renal arterial-venous oxygen shunting contributes to dynamic regulation of renal oxygenation. Am J Physiol Renal Physiol 2007, 292(6):F1726-33. 10.1152/ajprenal.00436.2006, 17327497.
    • (2007) Am J Physiol Renal Physiol , vol.292 , Issue.6
    • Leong, C.L.1
  • 56
    • 4043123181 scopus 로고    scopus 로고
    • Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells
    • 10.1161/01.RES.0000137173.42723.fb, 15217912
    • Archer SL, et al. Preferential expression and function of voltage-gated, O2-sensitive K+ channels in resistance pulmonary arteries explains regional heterogeneity in hypoxic pulmonary vasoconstriction: ionic diversity in smooth muscle cells. Circ Res 2004, 95(3):308-18. 10.1161/01.RES.0000137173.42723.fb, 15217912.
    • (2004) Circ Res , vol.95 , Issue.3 , pp. 308-318
    • Archer, S.L.1
  • 57
    • 55549145472 scopus 로고    scopus 로고
    • Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung
    • 10.1164/rccm.200712-1890OC, 2643223, 18689465
    • Leonard MO, et al. Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung. Am J Respir Crit Care Med 2008, 178(9):977-83. 10.1164/rccm.200712-1890OC, 2643223, 18689465.
    • (2008) Am J Respir Crit Care Med , vol.178 , Issue.9 , pp. 977-983
    • Leonard, M.O.1
  • 58
    • 33751343445 scopus 로고    scopus 로고
    • Vascular endothelial growth factor mRNA and protein do not change in parallel during non-inflammatory skeletal muscle ischaemia in rat
    • 10.1113/jphysiol.2006.113357, 1890445, 16990404
    • Milkiewicz M, et al. Vascular endothelial growth factor mRNA and protein do not change in parallel during non-inflammatory skeletal muscle ischaemia in rat. J Physiol 2006, 577(Pt 2):671-8. 10.1113/jphysiol.2006.113357, 1890445, 16990404.
    • (2006) J Physiol , vol.577 , Issue.PART 2 , pp. 671-678
    • Milkiewicz, M.1
  • 59
    • 13344259980 scopus 로고    scopus 로고
    • Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR
    • 10.1074/jbc.271.6.3154, 8621715
    • Cao Y, et al. Heterodimers of placenta growth factor/vascular endothelial growth factor. Endothelial activity, tumor cell expression, and high affinity binding to Flk-1/KDR. J Biol Chem 1996, 271(6):3154-62. 10.1074/jbc.271.6.3154, 8621715.
    • (1996) J Biol Chem , vol.271 , Issue.6 , pp. 3154-3162
    • Cao, Y.1
  • 60
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • 10.1038/87904, 11329059
    • Carmeliet P, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001, 7(5):575-83. 10.1038/87904, 11329059.
    • (2001) Nat Med , vol.7 , Issue.5 , pp. 575-583
    • Carmeliet, P.1
  • 61
    • 0033660171 scopus 로고    scopus 로고
    • Inhibition of VEGF receptors causes lung cell apoptosis and emphysema
    • 10.1172/JCI10259, 387249, 11104784
    • Kasahara Y, et al. Inhibition of VEGF receptors causes lung cell apoptosis and emphysema. J Clin Invest 2000, 106(11):1311-9. 10.1172/JCI10259, 387249, 11104784.
    • (2000) J Clin Invest , vol.106 , Issue.11 , pp. 1311-1319
    • Kasahara, Y.1
  • 62
    • 18844473540 scopus 로고    scopus 로고
    • Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia
    • Bellomo D, et al. Mice lacking the vascular endothelial growth factor-B gene (Vegfb) have smaller hearts, dysfunctional coronary vasculature, and impaired recovery from cardiac ischemia. Circ Res 2000, 86(2):E29-35.
    • (2000) Circ Res , vol.86 , Issue.2
    • Bellomo, D.1
  • 63
    • 0141788312 scopus 로고    scopus 로고
    • Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis
    • 10.1002/art.11232, 13130487
    • Mould AW, et al. Vegfb gene knockout mice display reduced pathology and synovial angiogenesis in both antigen-induced and collagen-induced models of arthritis. Arthritis Rheum 2003, 48(9):2660-9. 10.1002/art.11232, 13130487.
    • (2003) Arthritis Rheum , vol.48 , Issue.9 , pp. 2660-2669
    • Mould, A.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.