Deferoxamine regulates neuroinflammation and iron homeostasis in a mouse model of postoperative cognitive dysfunction

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Li, Yuping ^a   Pan, Ke ^a   Chen, Lin ^a   Ning, Jiao lin ^a   Li, Xiaojun ^a   Yang, Ting ^b   Terrando, Niccolò ^b   Gu, Jianteng ^a   Tao, Guocai ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Cytokines; Hippocampus; Iron; Microglia; Surgery

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOKINE; DEFEROXAMINE; FERRITIN; FERROPORTIN; HEPCIDIN; IRON; MITOGEN ACTIVATED PROTEIN KINASE P38; NATURAL RESISTANCE ASSOCIATED MACROPHAGE PROTEIN 2; NEUROTROPHIC FACTOR; SIDEROPHORE;

ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; C57BL 6 MOUSE; CELL ACTIVATION; CONDITIONING; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEAR; GENERAL ANESTHESIA; HIPPOCAMPUS; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; IRON HOMEOSTASIS; LAPAROTOMY; MALE; MEMORY; MICROGLIA; MORRIS WATER MAZE TEST; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; POSTOPERATIVE COGNITIVE DYSFUNCTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; COGNITION DISORDERS; DISEASE MODEL; DRUG EFFECTS; ENCEPHALITIS; MAZE TEST; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; POSTOPERATIVE COMPLICATIONS; TIME FACTOR; TRANSFORMED CELL LINE;

ANIMALS; CELL LINE, TRANSFORMED; COGNITION DISORDERS; CONDITIONING (PSYCHOLOGY); DEFEROXAMINE; DISEASE MODELS, ANIMAL; ENCEPHALITIS; FEAR; HOMEOSTASIS; IRON; LAPAROTOMY; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICROGLIA; OXIDATIVE STRESS; POSTOPERATIVE COMPLICATIONS; SIDEROPHORES; TIME FACTORS;

EID: 84991257367     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0740-2     Document Type: Article

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