Surgical trauma induces iron accumulation and oxidative stress in a rodent model of postoperative cognitive dysfunction

Biological Trace Element Research

Volumn 151, Issue 2, 2013, Pages 277-283

  An, Li Na ^a,b   Yue, Yang ^b   Guo, Wen Zhi ^a   Miao, Yu Liang ^a   Mi, Wei Dong ^a   Zhang, Hong ^a   Lei, Zhi Li ^b   Han, Shu Jun ^b   Dong, Lan ^b  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b GENERAL HOSPITAL OF CHINESE PEOPLE'S ARMED POLICE FORCES   (China)

Author keywords

Brain; Iron; Oxidative stress; Postoperative cognitive dysfunction; Working memory

Indexed keywords

CD71 ANTIGEN; FERRITIN; IRON; IRON REGULATORY PROTEIN 1; MALONALDEHYDE; IRON REGULATORY PROTEIN 2; SUPEROXIDE DISMUTASE; TFR1 PROTEIN, RAT; TRANSFERRIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; HIPPOCAMPUS; IRON BALANCE; IRON BLOOD LEVEL; IRON OVERLOAD; IRON STORAGE; LIPID PEROXIDATION; MALE; MAZE TEST; MENTAL FUNCTION; NONHUMAN; OXIDATIVE STRESS; POSTOPERATIVE COGNITIVE DYSFUNCTION; POSTOPERATIVE PERIOD; RAT; UPREGULATION; WORKING MEMORY; ANIMAL; BLOOD; COGNITION; COGNITIVE DEFECT; ENZYME ACTIVATION; ENZYME ASSAY; HOMEOSTASIS; LEARNING; METABOLISM; PATHOLOGY; PHYSIOLOGY; POSTOPERATIVE COMPLICATION; RANDOMIZATION; SPLENECTOMY; SPRAGUE DAWLEY RAT; TIME;

ANIMALIA; RATTUS; RODENTIA;

ANIMALS; COGNITION; COGNITION DISORDERS; ENZYME ACTIVATION; ENZYME ASSAYS; FERRITINS; HOMEOSTASIS; IRON; IRON REGULATORY PROTEIN 2; LEARNING; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; MAZE LEARNING; OXIDATIVE STRESS; POSTOPERATIVE COMPLICATIONS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, TRANSFERRIN; SPLENECTOMY; SUPEROXIDE DISMUTASE; TIME FACTORS;

MLCS; MLOWN;

EID: 84879032367     PISSN: 01634984     EISSN: 15590720     Source Type: Journal    
DOI: 10.1007/s12011-012-9564-9     Document Type: Article

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