Systemic inflammation impairs attention and cognitive flexibility but not associative learning in aged rats: Possible implications for delirium

Frontiers in Aging Neuroscience

Volumn 6, Issue JUN, 2014, Pages

  Culley, Deborah J ^a   Snayd, Mary ^a   Baxter, Mark G ^b   Xie, Zhongcong ^c   Lee, In Ho ^d   Rudolph, James ^a   Inouye, Sharon K ^e   Marcantonio, Edward R ^e   Crosby, Gregory ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Kwandong University College of Medicine   (South Korea)

^e BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Aging neuroscience; Ccl2; Frontal cortex; Inflammation; Lipopolysaccharides; Rats; Set shifting

Indexed keywords

LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR ALPHA;

AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENTION; COGNITION; CONTROLLED STUDY; DELIRIUM; DISCRIMINATION LEARNING; ENZYME LINKED IMMUNOSORBENT ASSAY; EXECUTIVE FUNCTION; EXPERIMENTAL BEHAVIORAL TEST; FRONTAL CORTEX; INFLAMMATION; LEARNING; NONHUMAN; PATHOGENESIS; PLASMA; PREFRONTAL CORTEX; RAT; STATE DEPENDENT LEARNING;

EID: 84904565716     PISSN: None     EISSN: 16634365     Source Type: Journal    
DOI: 10.3389/fnagi.2014.00107     Document Type: Article

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