Madecassic Acid protects against hypoxia-induced oxidative stress in retinal microvascular endothelial cells via ROS-mediated endoplasmic reticulum stress

Biomedicine and Pharmacotherapy

Volumn 84, Issue , 2016, Pages 845-852

  Yang, Boyu ^a   Xu, Yue ^a   Hu, Yaguang ^a   Luo, Yiwen ^a   Lu, Xi ^a   Tsui, Ching Kit ^a   Lu, Lin ^a   Liang, Xiaoling ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; ATF4; Endoplasmic reticulum stress; Human retinal microvascular endothelial cells; Madecassic acid; Oxidative stress; ROS

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 12; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE PEROXIDASE; INITIATION FACTOR 2ALPHA; MADECASSIC ACID; MALONALDEHYDE; MESSENGER RNA; OXIDOREDUCTASE; PROTECTIVE AGENT; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; ATF4 PROTEIN, HUMAN; LACTATE DEHYDROGENASE; TRITERPENE;

APOPTOSIS; ARTICLE; CAPILLARY ENDOTHELIAL CELL; CELL PROTECTION; CELL VIABILITY; CENTELLA ASIATICA; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOFLUORESCENCE; MEDICINAL PLANT; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RETINA CELL; RETINAL MICROVASCULAR ENDOTHELIAL CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL HYPOXIA; CELL NUCLEUS; CHEMISTRY; DRUG EFFECTS; ENDOTHELIUM CELL; ENZYMOLOGY; METABOLISM; MICROVASCULATURE; PATHOLOGY; PROTEIN TRANSPORT; RETINA; UNFOLDED PROTEIN RESPONSE;

ACTIVATING TRANSCRIPTION FACTOR 4; CELL HYPOXIA; CELL NUCLEUS; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIAL CELLS; GLUTATHIONE PEROXIDASE; HUMANS; L-LACTATE DEHYDROGENASE; MALONDIALDEHYDE; MICROVESSELS; OXIDATIVE STRESS; PROTECTIVE AGENTS; PROTEIN TRANSPORT; REACTIVE OXYGEN SPECIES; RETINA; SUPEROXIDE DISMUTASE; TRITERPENES; UNFOLDED PROTEIN RESPONSE;

EID: 84991109114     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2016.10.015     Document Type: Article

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