SalA attenuates hypoxia-induced endothelial endoplasmic reticulum stress and apoptosis via down-regulation of VLDL receptor expression

Cellular Physiology and Biochemistry

Volumn 35, Issue 1, 2015, Pages 17-28

  Xie, Ping ^a   Duan, Yingchun ^a   Guo, Xianzhi ^a   Hu, Lina ^a   Yu, Minghua ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Apoptosis; Endothelial endoplasmic reticulum stress; Hypoxia; Salvianolic acid A; VLDL receptor

Indexed keywords

CASPASE 3; CYTOPROTECTIVE AGENT; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA; NOOTROPIC AGENT; PROTEIN BAX; SALVIANOLIC ACID A; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN RECEPTOR; CAFFEIC ACID DERIVATIVE; LACTIC ACID DERIVATIVE; LOW DENSITY LIPOPROTEIN RECEPTOR; PROTEIN BINDING; PROTON PUMP INHIBITOR; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CELL HYPOXIA; CELL PROTECTION; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; EXPERIMENTAL HYPOXIA; FLOW CYTOMETRY; GENE ACTIVITY; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOBLOTTING; IN VITRO STUDY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR DOWN REGULATION; UMBILICAL VEIN ENDOTHELIAL CELL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GENETICS; METABOLISM; RNA INTERFERENCE;

APOPTOSIS; CAFFEIC ACIDS; CELL HYPOXIA; DOWN-REGULATION; ENDOPLASMIC RETICULUM STRESS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; LACTATES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTON PUMP INHIBITORS; RECEPTORS, LDL; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84920792588     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000369671     Document Type: Article

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