Anti-inflammatory effects of madecassic acid via the suppression of NF-κB pathway in LPS-induced RAW 264.7 macrophage cells

Planta Medica

Volumn 76, Issue 3, 2010, Pages 251-257

  Won, Jong Heon ^a   Shin, Ji Sun ^a   Park, Hee Juhn ^b   Jung, Hyun Ju ^c   Koh, Duck Jae ^a   Jo, Baek Geon ^a   Lee, Jin Yong ^a   Yun, Kijoo ^d   Lee, Kyung Tae ^a  

^a Kyung Hee University   (South Korea)

^b Sangji University   (South Korea)

^c Wonkwang University   (South Korea)

^d Gangneung Wonju National University   (South Korea)

Author keywords

Antiinflammation; Centella asiatica; Madecassic acid; Madecassoside; Nuclear factor B; Umbelliferae

Indexed keywords

ANTIINFLAMMATORY AGENT; CYCLOOXYGENASE 2; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MADECASSIC ACID; MADECASSOSIDE; MESSENGER RNA; NITRIC OXIDE; P65 PROTEIN; PROSTAGLANDIN E2; PROTEIN; TRITERPENOID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CENTELLA ASIATICA; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENCY; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; CENTELLA; CYCLOOXYGENASE 2; DOWN-REGULATION; INFLAMMATION MEDIATORS; INTERLEUKIN-1BETA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; PLANT EXTRACTS; RNA, MESSENGER; TRITERPENES; TUMOR NECROSIS FACTOR-ALPHA;

APIACEAE; CENTELLA ASIATICA; MURINAE;

EID: 77049125035     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0029-1186142     Document Type: Article

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