메뉴 건너뛰기




Volumn 5, Issue 9, 2016, Pages 795-803

Interactions between host genetics and gut microbiome in diabetes and metabolic syndrome

Author keywords

Environment; Host genetics; Metabolic syndrome; Microbial diversity; Microbiome; Microbiota; Obesity

Indexed keywords

BACTEROIDETES; DIABETES MELLITUS; DIET; FECAL MICROBIOTA TRANSPLANTATION; FIRMICUTES; GENETICS; GENOTYPE ENVIRONMENT INTERACTION; HOST PATHOGEN INTERACTION; HUMAN; INSULIN RESISTANCE; INTESTINE FLORA; METABOLIC SYNDROME X; MURINE MODEL; NONHUMAN; OBESITY; PATHOGENESIS; PHYLOGENY; PRIORITY JOURNAL; REVIEW; WEIGHT GAIN;

EID: 84991056627     PISSN: None     EISSN: 22128778     Source Type: Journal    
DOI: 10.1016/j.molmet.2016.07.004     Document Type: Review
Times cited : (132)

References (77)
  • 1
    • 84931295496 scopus 로고    scopus 로고
    • Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook
    • [1] Kelly, C.R., Kahn, S., Kashyap, P., Laine, L., Rubin, D., Atreja, A., et al. Update on fecal microbiota transplantation 2015: indications, methodologies, mechanisms, and outlook. Gastroenterology 149 (2015), 223–237.
    • (2015) Gastroenterology , vol.149 , pp. 223-237
    • Kelly, C.R.1    Kahn, S.2    Kashyap, P.3    Laine, L.4    Rubin, D.5    Atreja, A.6
  • 2
    • 77950251400 scopus 로고    scopus 로고
    • A human gut microbial gene catalogue established by metagenomic sequencing
    • [2] Qin, J., Li, R., Raes, J., Arumugam, M., Burgdorf, K.S., Manichanh, C., et al. A human gut microbial gene catalogue established by metagenomic sequencing. Nature 464 (2010), 59–65.
    • (2010) Nature , vol.464 , pp. 59-65
    • Qin, J.1    Li, R.2    Raes, J.3    Arumugam, M.4    Burgdorf, K.S.5    Manichanh, C.6
  • 3
    • 84866168894 scopus 로고    scopus 로고
    • Functional interactions between the gut microbiota and host metabolism
    • [3] Tremaroli, V., Backhed, F., Functional interactions between the gut microbiota and host metabolism. Nature 489 (2012), 242–249.
    • (2012) Nature , vol.489 , pp. 242-249
    • Tremaroli, V.1    Backhed, F.2
  • 4
    • 84929502588 scopus 로고    scopus 로고
    • Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function
    • [4] Kelly, C.J., Zheng, L., Campbell, E.L., Saeedi, B., Scholz, C.C., Bayless, A.J., et al. Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function. Cell Host Microbe 17 (2015), 662–671.
    • (2015) Cell Host Microbe , vol.17 , pp. 662-671
    • Kelly, C.J.1    Zheng, L.2    Campbell, E.L.3    Saeedi, B.4    Scholz, C.C.5    Bayless, A.J.6
  • 5
    • 84973667684 scopus 로고    scopus 로고
    • Acetate mediates a microbiome–brain–beta-cell axis to promote metabolic syndrome
    • [5] Perry, R.J., Peng, L., Barry, N.A., Cline, G.W., Zhang, D., Cardone, R.L., et al. Acetate mediates a microbiome–brain–beta-cell axis to promote metabolic syndrome. Nature 534 (2016), 213–217.
    • (2016) Nature , vol.534 , pp. 213-217
    • Perry, R.J.1    Peng, L.2    Barry, N.A.3    Cline, G.W.4    Zhang, D.5    Cardone, R.L.6
  • 7
    • 84975317355 scopus 로고    scopus 로고
    • Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring
    • [7] Buffington, S.A., Di Prisco, G.V., Auchtung, T.A., Ajami, N.J., Petrosino, J.F., Costa-Mattioli, M., Microbial reconstitution reverses maternal diet-induced social and synaptic deficits in offspring. Cell 165 (2016), 1762–1775.
    • (2016) Cell , vol.165 , pp. 1762-1775
    • Buffington, S.A.1    Di Prisco, G.V.2    Auchtung, T.A.3    Ajami, N.J.4    Petrosino, J.F.5    Costa-Mattioli, M.6
  • 8
    • 84971575056 scopus 로고    scopus 로고
    • Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior
    • [8] Gacias, M., Gaspari, S., Santos, P.M., Tamburini, S., Andrade, M., Zhang, F., et al. Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior. Elife, 5, 2016.
    • (2016) Elife , vol.5
    • Gacias, M.1    Gaspari, S.2    Santos, P.M.3    Tamburini, S.4    Andrade, M.5    Zhang, F.6
  • 10
    • 84873342775 scopus 로고    scopus 로고
    • Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
    • [10] Sayin, S.I., Wahlstrom, A., Felin, J., Jantti, S., Marschall, H.U., Bamberg, K., et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metabolism 17 (2013), 225–235.
    • (2013) Cell Metabolism , vol.17 , pp. 225-235
    • Sayin, S.I.1    Wahlstrom, A.2    Felin, J.3    Jantti, S.4    Marschall, H.U.5    Bamberg, K.6
  • 11
    • 84991053856 scopus 로고    scopus 로고
    • Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism
    • 12 Jul
    • [11] Wahlstrom, A., Sayin, S.I., Marschall, H.U., Backhed, F., Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism. Cell Metabolism 24:1 (12 Jul 2016), 41–50.
    • (2016) Cell Metabolism , vol.24 , Issue.1 , pp. 41-50
    • Wahlstrom, A.1    Sayin, S.I.2    Marschall, H.U.3    Backhed, F.4
  • 12
    • 84890550163 scopus 로고    scopus 로고
    • Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
    • [12] Arpaia, N., Campbell, C., Fan, X., Dikiy, S., van der Veeken, J., deRoos, P., et al. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation. Nature 504 (2013), 451–455.
    • (2013) Nature , vol.504 , pp. 451-455
    • Arpaia, N.1    Campbell, C.2    Fan, X.3    Dikiy, S.4    van der Veeken, J.5    deRoos, P.6
  • 13
    • 84862637797 scopus 로고    scopus 로고
    • Gut immune maturation depends on colonization with a host-specific microbiota
    • [13] Chung, H., Pamp, S.J., Hill, J.A., Surana, N.K., Edelman, S.M., Troy, E.B., et al. Gut immune maturation depends on colonization with a host-specific microbiota. Cell 149 (2012), 1578–1593.
    • (2012) Cell , vol.149 , pp. 1578-1593
    • Chung, H.1    Pamp, S.J.2    Hill, J.A.3    Surana, N.K.4    Edelman, S.M.5    Troy, E.B.6
  • 17
    • 84978619185 scopus 로고    scopus 로고
    • Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
    • [17] Dominguez-Bello, M.G., De Jesus-Laboy, K.M., Shen, N., Cox, L.M., Amir, A., Gonzalez, A., et al. Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer. Nature Medicine 22:3 (2016), 250–253.
    • (2016) Nature Medicine , vol.22 , Issue.3 , pp. 250-253
    • Dominguez-Bello, M.G.1    De Jesus-Laboy, K.M.2    Shen, N.3    Cox, L.M.4    Amir, A.5    Gonzalez, A.6
  • 18
    • 84930860669 scopus 로고    scopus 로고
    • Comparison of the gut microbiota profile in breast-fed and formula-fed Korean infants using pyrosequencing
    • [18] Lee, S.A., Lim, J.Y., Kim, B.S., Cho, S.J., Kim, N.Y., Kim, O.B., et al. Comparison of the gut microbiota profile in breast-fed and formula-fed Korean infants using pyrosequencing. Nutrition Research and Practice 9 (2015), 242–248.
    • (2015) Nutrition Research and Practice , vol.9 , pp. 242-248
    • Lee, S.A.1    Lim, J.Y.2    Kim, B.S.3    Cho, S.J.4    Kim, N.Y.5    Kim, O.B.6
  • 19
    • 84959287341 scopus 로고    scopus 로고
    • Human breast milk and infant formulas differentially modify the intestinal microbiota in human infants and host physiology in rats
    • [19] Liu, Z., Roy, N.C., Guo, Y., Jia, H., Ryan, L., Samuelsson, L., et al. Human breast milk and infant formulas differentially modify the intestinal microbiota in human infants and host physiology in rats. The Journal of Nutrition 146 (2016), 191–199.
    • (2016) The Journal of Nutrition , vol.146 , pp. 191-199
    • Liu, Z.1    Roy, N.C.2    Guo, Y.3    Jia, H.4    Ryan, L.5    Samuelsson, L.6
  • 21
    • 84963958983 scopus 로고    scopus 로고
    • The effect of heritability and host genetics on the gut microbiota and metabolic syndrome
    • [21] Lim, M.Y., You, H.J., Yoon, H.S., Kwon, B., Lee, J.Y., Lee, S., et al. The effect of heritability and host genetics on the gut microbiota and metabolic syndrome. Gut, 2016, 10.1136/gutjnl-2015-311326.
    • (2016) Gut
    • Lim, M.Y.1    You, H.J.2    Yoon, H.S.3    Kwon, B.4    Lee, J.Y.5    Lee, S.6
  • 22
    • 33645982255 scopus 로고    scopus 로고
    • From mice to men: insights into the insulin resistance syndromes
    • [22] Biddinger, S.B., Kahn, C.R., From mice to men: insights into the insulin resistance syndromes. Annual Review of Physiology 68 (2006), 123–158.
    • (2006) Annual Review of Physiology , vol.68 , pp. 123-158
    • Biddinger, S.B.1    Kahn, C.R.2
  • 23
    • 84925301012 scopus 로고    scopus 로고
    • Knockout mouse models of insulin signaling: relevance past and future
    • [23] Bunner, A.E., Chandrasekera, P.C., Barnard, N.D., Knockout mouse models of insulin signaling: relevance past and future. World Journal of Diabetes 5 (2014), 146–159.
    • (2014) World Journal of Diabetes , vol.5 , pp. 146-159
    • Bunner, A.E.1    Chandrasekera, P.C.2    Barnard, N.D.3
  • 25
    • 33845567553 scopus 로고    scopus 로고
    • Genetics of obesity in humans
    • [25] Farooqi, S., O'Rahilly, S., Genetics of obesity in humans. Endocrine Reviews 27 (2006), 710–718.
    • (2006) Endocrine Reviews , vol.27 , pp. 710-718
    • Farooqi, S.1    O'Rahilly, S.2
  • 27
    • 84941915615 scopus 로고    scopus 로고
    • Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of obesity-related traits
    • [27] Karaderi, T., Drong, A.W., Lindgren, C.M., Insights into the genetic susceptibility to type 2 diabetes from genome-wide association studies of obesity-related traits. Current Diabetes Reports, 15, 2015, 83.
    • (2015) Current Diabetes Reports , vol.15 , pp. 83
    • Karaderi, T.1    Drong, A.W.2    Lindgren, C.M.3
  • 29
    • 84884500386 scopus 로고    scopus 로고
    • Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications
    • [29] Stefan, N., Haring, H.U., Hu, F.B., Schulze, M.B., Metabolically healthy obesity: epidemiology, mechanisms, and clinical implications. The Lancet Diabetes & Endocrinology 1 (2013), 152–162.
    • (2013) The Lancet Diabetes & Endocrinology , vol.1 , pp. 152-162
    • Stefan, N.1    Haring, H.U.2    Hu, F.B.3    Schulze, M.B.4
  • 31
    • 84955587698 scopus 로고    scopus 로고
    • Human ‘brite/beige’ adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice
    • [31] Min, S.Y., Kady, J., Nam, M., Rojas-Rodriguez, R., Berkenwald, A., Kim, J.H., et al. Human ‘brite/beige’ adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice. Nature Medicine 22 (2016), 312–318.
    • (2016) Nature Medicine , vol.22 , pp. 312-318
    • Min, S.Y.1    Kady, J.2    Nam, M.3    Rojas-Rodriguez, R.4    Berkenwald, A.5    Kim, J.H.6
  • 32
    • 67650242165 scopus 로고    scopus 로고
    • High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity
    • [32] Saito, M., Okamatsu-Ogura, Y., Matsushita, M., Watanabe, K., Yoneshiro, T., Nio-Kobayashi, J., et al. High incidence of metabolically active brown adipose tissue in healthy adult humans: effects of cold exposure and adiposity. Diabetes 58 (2009), 1526–1531.
    • (2009) Diabetes , vol.58 , pp. 1526-1531
    • Saito, M.1    Okamatsu-Ogura, Y.2    Matsushita, M.3    Watanabe, K.4    Yoneshiro, T.5    Nio-Kobayashi, J.6
  • 34
    • 84923169934 scopus 로고    scopus 로고
    • New genetic loci link adipose and insulin biology to body fat distribution
    • [34] Shungin, D., Winkler, T.W., Croteau-Chonka, D.C., Ferreira, T., Locke, A.E., Magi, R., et al. New genetic loci link adipose and insulin biology to body fat distribution. Nature 518 (2015), 187–196.
    • (2015) Nature , vol.518 , pp. 187-196
    • Shungin, D.1    Winkler, T.W.2    Croteau-Chonka, D.C.3    Ferreira, T.4    Locke, A.E.5    Magi, R.6
  • 35
    • 84940707952 scopus 로고    scopus 로고
    • A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis
    • [35] Stanford, K.I., Middelbeek, R.J., Townsend, K.L., Lee, M.Y., Takahashi, H., So, K., et al. A novel role for subcutaneous adipose tissue in exercise-induced improvements in glucose homeostasis. Diabetes 64 (2015), 2002–2014.
    • (2015) Diabetes , vol.64 , pp. 2002-2014
    • Stanford, K.I.1    Middelbeek, R.J.2    Townsend, K.L.3    Lee, M.Y.4    Takahashi, H.5    So, K.6
  • 36
    • 42649144463 scopus 로고    scopus 로고
    • Beneficial effects of subcutaneous fat transplantation on metabolism
    • [36] Tran, T.T., Yamamoto, Y., Gesta, S., Kahn, C.R., Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metabolism 7 (2008), 410–420.
    • (2008) Cell Metabolism , vol.7 , pp. 410-420
    • Tran, T.T.1    Yamamoto, Y.2    Gesta, S.3    Kahn, C.R.4
  • 39
    • 84870302181 scopus 로고    scopus 로고
    • MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity
    • [39] Kusminski, C.M., Holland, W.L., Sun, K., Park, J., Spurgin, S.B., Lin, Y., et al. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity. Nature Medicine 18 (2012), 1539–1549.
    • (2012) Nature Medicine , vol.18 , pp. 1539-1549
    • Kusminski, C.M.1    Holland, W.L.2    Sun, K.3    Park, J.4    Spurgin, S.B.5    Lin, Y.6
  • 40
    • 84977163097 scopus 로고    scopus 로고
    • An algorithm for designing minimal microbial communities with desired metabolic capacities
    • [40] Eng, A., Borenstein, E., An algorithm for designing minimal microbial communities with desired metabolic capacities. Bioinformatics 32 (2016), 2008–2016.
    • (2016) Bioinformatics , vol.32 , pp. 2008-2016
    • Eng, A.1    Borenstein, E.2
  • 41
    • 84964768884 scopus 로고    scopus 로고
    • Visualization of metabolic interaction networks in microbial communities using VisANT 5.0
    • [41] Granger, B.R., Chang, Y.C., Wang, Y., DeLisi, C., Segre, D., Hu, Z., Visualization of metabolic interaction networks in microbial communities using VisANT 5.0. PLoS Computational Biology, 12, 2016, e1004875.
    • (2016) PLoS Computational Biology , vol.12 , pp. e1004875
    • Granger, B.R.1    Chang, Y.C.2    Wang, Y.3    DeLisi, C.4    Segre, D.5    Hu, Z.6
  • 42
    • 85041927917 scopus 로고    scopus 로고
    • Metabolic model-based integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation
    • [42] Noecker, C., Eng, A., Srinivasan, S., Theriot, C.M., Young, V.B., Jansson, J.K., et al. Metabolic model-based integration of microbiome taxonomic and metabolomic profiles elucidates mechanistic links between ecological and metabolic variation. mSystems, 1, 2016.
    • (2016) mSystems , vol.1
    • Noecker, C.1    Eng, A.2    Srinivasan, S.3    Theriot, C.M.4    Young, V.B.5    Jansson, J.K.6
  • 43
    • 84911895975 scopus 로고    scopus 로고
    • Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes
    • [43] Kluth, O., Matzke, D., Schulze, G., Schwenk, R.W., Joost, H.G., Schurmann, A., Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes. Diabetes 63 (2014), 4230–4238.
    • (2014) Diabetes , vol.63 , pp. 4230-4238
    • Kluth, O.1    Matzke, D.2    Schulze, G.3    Schwenk, R.W.4    Joost, H.G.5    Schurmann, A.6
  • 44
    • 9644260361 scopus 로고    scopus 로고
    • Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
    • [44] Almind, K., Kahn, C.R., Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes 53 (2004), 3274–3285.
    • (2004) Diabetes , vol.53 , pp. 3274-3285
    • Almind, K.1    Kahn, C.R.2
  • 48
    • 84880773540 scopus 로고    scopus 로고
    • QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects
    • [48] Lin, C., Theodorides, M.L., McDaniel, A.H., Tordoff, M.G., Zhang, Q., Li, X., et al. QTL analysis of dietary obesity in C57BL/6byj X 129P3/J F2 mice: diet- and sex-dependent effects. PLoS One, 8, 2013, e68776.
    • (2013) PLoS One , vol.8 , pp. e68776
    • Lin, C.1    Theodorides, M.L.2    McDaniel, A.H.3    Tordoff, M.G.4    Zhang, Q.5    Li, X.6
  • 49
    • 78049251400 scopus 로고    scopus 로고
    • A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease
    • [49] Mori, M.A., Liu, M., Bezy, O., Almind, K., Shapiro, H., Kasif, S., et al. A systems biology approach identifies inflammatory abnormalities between mouse strains prior to development of metabolic disease. Diabetes 59 (2010), 2960–2971.
    • (2010) Diabetes , vol.59 , pp. 2960-2971
    • Mori, M.A.1    Liu, M.2    Bezy, O.3    Almind, K.4    Shapiro, H.5    Kasif, S.6
  • 50
    • 0037872709 scopus 로고    scopus 로고
    • Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice
    • [50] Kulkarni, R.N., Almind, K., Goren, H.J., Winnay, J.N., Ueki, K., Okada, T., et al. Impact of genetic background on development of hyperinsulinemia and diabetes in insulin receptor/insulin receptor substrate-1 double heterozygous mice. Diabetes 52 (2003), 1528–1534.
    • (2003) Diabetes , vol.52 , pp. 1528-1534
    • Kulkarni, R.N.1    Almind, K.2    Goren, H.J.3    Winnay, J.N.4    Ueki, K.5    Okada, T.6
  • 52
    • 33847404482 scopus 로고    scopus 로고
    • Inhibition of protein kinase C epsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease
    • [51](b) Samuel, V.T., Liu, Z.X., Wang, A., Beddow, S.A., Geisler, J.G., Kahn, M., et al. Inhibition of protein kinase C epsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. The Journal of Clinical Investigation 117 (2007), 739–745.
    • (2007) The Journal of Clinical Investigation , vol.117 , pp. 739-745
    • Samuel, V.T.1    Liu, Z.X.2    Wang, A.3    Beddow, S.A.4    Geisler, J.G.5    Kahn, M.6
  • 53
    • 33845901507 scopus 로고    scopus 로고
    • Microbial ecology: human gut microbes associated with obesity
    • [52] Ley, R.E., Turnbaugh, P.J., Klein, S., Gordon, J.I., Microbial ecology: human gut microbes associated with obesity. Nature 444 (2006), 1022–1023.
    • (2006) Nature , vol.444 , pp. 1022-1023
    • Ley, R.E.1    Turnbaugh, P.J.2    Klein, S.3    Gordon, J.I.4
  • 54
    • 84862230115 scopus 로고    scopus 로고
    • Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii
    • [53] Million, M., Maraninchi, M., Henry, M., Armougom, F., Richet, H., Carrieri, P., et al. Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii. International Journal of Obesity 36 (2012), 817–825.
    • (2012) International Journal of Obesity , vol.36 , pp. 817-825
    • Million, M.1    Maraninchi, M.2    Henry, M.3    Armougom, F.4    Richet, H.5    Carrieri, P.6
  • 56
    • 53849104768 scopus 로고    scopus 로고
    • Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women
    • [55] Collado, M.C., Isolauri, E., Laitinen, K., Salminen, S., Distinct composition of gut microbiota during pregnancy in overweight and normal-weight women. American Journal of Clinical Nutrition 88 (2008), 894–899.
    • (2008) American Journal of Clinical Nutrition , vol.88 , pp. 894-899
    • Collado, M.C.1    Isolauri, E.2    Laitinen, K.3    Salminen, S.4
  • 57
    • 73949137604 scopus 로고    scopus 로고
    • Microbiota and SCFA in lean and overweight healthy subjects
    • [56] Schwiertz, A., Taras, D., Schafer, K., Beijer, S., Bos, N.A., Donus, C., et al. Microbiota and SCFA in lean and overweight healthy subjects. Obesity 18 (2010), 190–195.
    • (2010) Obesity , vol.18 , pp. 190-195
    • Schwiertz, A.1    Taras, D.2    Schafer, K.3    Beijer, S.4    Bos, N.A.5    Donus, C.6
  • 58
    • 85018193359 scopus 로고    scopus 로고
    • Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome
    • [57] Ussar, S., Griffin, N.W., Bezy, O., Fujisaka, S., Vienberg, S., Softic, S., et al. Interactions between gut microbiota, host genetics and diet modulate the predisposition to obesity and metabolic syndrome. Cell Metabolism 22 (2015), 516–530.
    • (2015) Cell Metabolism , vol.22 , pp. 516-530
    • Ussar, S.1    Griffin, N.W.2    Bezy, O.3    Fujisaka, S.4    Vienberg, S.5    Softic, S.6
  • 59
    • 41849127118 scopus 로고    scopus 로고
    • Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome
    • [58] Turnbaugh, P.J., Backhed, F., Fulton, L., Gordon, J.I., Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome. Cell Host Microbe 3 (2008), 213–223.
    • (2008) Cell Host Microbe , vol.3 , pp. 213-223
    • Turnbaugh, P.J.1    Backhed, F.2    Fulton, L.3    Gordon, J.I.4
  • 60
    • 84960253261 scopus 로고    scopus 로고
    • Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology
    • [59] Dao, M.C., Everard, A., Aron-Wisnewsky, J., Sokolovska, N., Prifti, E., Verger, E.O., et al. Akkermansia muciniphila and improved metabolic health during a dietary intervention in obesity: relationship with gut microbiome richness and ecology. Gut 65 (2016), 426–436.
    • (2016) Gut , vol.65 , pp. 426-436
    • Dao, M.C.1    Everard, A.2    Aron-Wisnewsky, J.3    Sokolovska, N.4    Prifti, E.5    Verger, E.O.6
  • 61
    • 84988876296 scopus 로고    scopus 로고
    • Faecalibacterium prausnitzii phylotypes in type two diabetic, obese, and lean control subjects
    • [60] Hippe, B., Remely, M., Aumueller, E., Pointner, A., Magnet, U., Haslberger, A.G., Faecalibacterium prausnitzii phylotypes in type two diabetic, obese, and lean control subjects. Benef Microbes, 2016, 1–8.
    • (2016) Benef Microbes , pp. 1-8
    • Hippe, B.1    Remely, M.2    Aumueller, E.3    Pointner, A.4    Magnet, U.5    Haslberger, A.G.6
  • 62
    • 84947460237 scopus 로고    scopus 로고
    • Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice
    • [61] Schneeberger, M., Everard, A., Gomez-Valades, A.G., Matamoros, S., Ramirez, S., Delzenne, N.M., et al. Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice. Scientific Reports, 5, 2015, 16643.
    • (2015) Scientific Reports , vol.5 , pp. 16643
    • Schneeberger, M.1    Everard, A.2    Gomez-Valades, A.G.3    Matamoros, S.4    Ramirez, S.5    Delzenne, N.M.6
  • 63
    • 84939609106 scopus 로고    scopus 로고
    • Effect of ethnicity and socioeconomic variation to the gut microbiota composition among pre-adolescent in Malaysia
    • [62](a) Chong, C.W., Ahmad, A.F., Lim, Y.A., Teh, C.S., Yap, I.K., Lee, S.C., et al. Effect of ethnicity and socioeconomic variation to the gut microbiota composition among pre-adolescent in Malaysia. Scientific Reports, 5, 2015, 13338.
    • (2015) Scientific Reports , vol.5 , pp. 13338
    • Chong, C.W.1    Ahmad, A.F.2    Lim, Y.A.3    Teh, C.S.4    Yap, I.K.5    Lee, S.C.6
  • 65
    • 84921900196 scopus 로고    scopus 로고
    • Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes
    • [63] Kemppainen, K.M., Ardissone, A.N., Davis-Richardson, A.G., Fagen, J.R., Gano, K.A., Leon-Novelo, L.G., et al. Early childhood gut microbiomes show strong geographic differences among subjects at high risk for type 1 diabetes. Diabetes Care 38 (2015), 329–332.
    • (2015) Diabetes Care , vol.38 , pp. 329-332
    • Kemppainen, K.M.1    Ardissone, A.N.2    Davis-Richardson, A.G.3    Fagen, J.R.4    Gano, K.A.5    Leon-Novelo, L.G.6
  • 67
    • 84959198631 scopus 로고    scopus 로고
    • Lower neighborhood socioeconomic status associated with reduced diversity of the colonic microbiota in healthy adults
    • [65] Miller, G.E., Engen, P.A., Gillevet, P.M., Shaikh, M., Sikaroodi, M., Forsyth, C.B., et al. Lower neighborhood socioeconomic status associated with reduced diversity of the colonic microbiota in healthy adults. PLoS One, 11, 2016, e0148952.
    • (2016) PLoS One , vol.11 , pp. e0148952
    • Miller, G.E.1    Engen, P.A.2    Gillevet, P.M.3    Shaikh, M.4    Sikaroodi, M.5    Forsyth, C.B.6
  • 68
    • 84968901892 scopus 로고    scopus 로고
    • Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity
    • [66] Zhernakova, A., Kurilshikov, A., Bonder, M.J., Tigchelaar, E.F., Schirmer, M., Vatanen, T., et al. Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity. Science 352 (2016), 565–569.
    • (2016) Science , vol.352 , pp. 565-569
    • Zhernakova, A.1    Kurilshikov, A.2    Bonder, M.J.3    Tigchelaar, E.F.4    Schirmer, M.5    Vatanen, T.6
  • 69
    • 84866146940 scopus 로고    scopus 로고
    • Diversity, stability and resilience of the human gut microbiota
    • [67] Lozupone, C.A., Stombaugh, J.I., Gordon, J.I., Jansson, J.K., Knight, R., Diversity, stability and resilience of the human gut microbiota. Nature 489 (2012), 220–230.
    • (2012) Nature , vol.489 , pp. 220-230
    • Lozupone, C.A.1    Stombaugh, J.I.2    Gordon, J.I.3    Jansson, J.K.4    Knight, R.5
  • 70
    • 84893776494 scopus 로고    scopus 로고
    • Impact of ethnicity, geography, and disease on the microbiota in health and inflammatory bowel disease
    • [68] Prideaux, L., Kang, S., Wagner, J., Buckley, M., Mahar, J.E., De Cruz, P., et al. Impact of ethnicity, geography, and disease on the microbiota in health and inflammatory bowel disease. Inflammatory Bowel Diseases 19 (2013), 2906–2918.
    • (2013) Inflammatory Bowel Diseases , vol.19 , pp. 2906-2918
    • Prideaux, L.1    Kang, S.2    Wagner, J.3    Buckley, M.4    Mahar, J.E.5    De Cruz, P.6
  • 71
    • 78649686679 scopus 로고    scopus 로고
    • A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes
    • 1844–1854 e1841
    • [69] Willing, B.P., Dicksved, J., Halfvarson, J., Andersson, A.F., Lucio, M., Zheng, Z., et al. A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes. Gastroenterology, 139, 2010 1844–1854 e1841.
    • (2010) Gastroenterology , vol.139
    • Willing, B.P.1    Dicksved, J.2    Halfvarson, J.3    Andersson, A.F.4    Lucio, M.5    Zheng, Z.6
  • 72
    • 84962502894 scopus 로고    scopus 로고
    • A healthy gastrointestinal microbiome is dependent on dietary diversity
    • [70] Heiman, M.L., Greenway, F.L., A healthy gastrointestinal microbiome is dependent on dietary diversity. Molecular Metabolism 5 (2016), 317–320.
    • (2016) Molecular Metabolism , vol.5 , pp. 317-320
    • Heiman, M.L.1    Greenway, F.L.2
  • 75
    • 84862491799 scopus 로고    scopus 로고
    • Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits
    • [73] McKnite, A.M., Perez-Munoz, M.E., Lu, L., Williams, E.G., Brewer, S., Andreux, P.A., et al. Murine gut microbiota is defined by host genetics and modulates variation of metabolic traits. PLoS One, 7, 2012, e39191.
    • (2012) PLoS One , vol.7 , pp. e39191
    • McKnite, A.M.1    Perez-Munoz, M.E.2    Lu, L.3    Williams, E.G.4    Brewer, S.5    Andreux, P.A.6
  • 76
    • 84884127512 scopus 로고    scopus 로고
    • Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
    • [74] Langille, M.G., Zaneveld, J., Caporaso, J.G., McDonald, D., Knights, D., Reyes, J.A., et al. Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences. Nature Biotechnology 31 (2013), 814–821.
    • (2013) Nature Biotechnology , vol.31 , pp. 814-821
    • Langille, M.G.1    Zaneveld, J.2    Caporaso, J.G.3    McDonald, D.4    Knights, D.5    Reyes, J.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.