Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8+ T Cell-Mediated Immunity in Colorectal Cancer

Immunity

Volumn 45, Issue 3, 2016, Pages 641-655

  Bhattacharya, Nupur ^a   Yuan, Robert ^a   Prestwood, Tyler R ^a   Penny, Hweixian Leong ^a   DiMaio, Michael A ^a   Reticker Flynn, Nathan E ^a   Krois, Charles R ^b   Kenkel, Justin A ^a   Pham, Tho D ^a   Carmi, Yaron ^a   Tolentino, Lorna ^a   Choi, Okmi ^a   Hulett, Reyna ^a   Wang, Jinshan ^b   Winer, Daniel A ^c   Napoli, Joseph L ^b   Engleman, Edgar G ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY HEALTH NETWORK   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 26A1; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; LIAROZOLE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; RETINOIC ACID; TUMOR NECROSIS FACTOR; CYTOCHROME P450 FAMILY 26;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER PROGNOSIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL MEDIATED CYTOTOXICITY; CELLULAR IMMUNITY; COLITIS; COLON ADENOCARCINOMA; COLON CARCINOGENESIS; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXIC T LYMPHOCYTE; FEMALE; HUMAN; HUMAN TISSUE; INTESTINE FLORA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TUMOR CELL; TUMOR VOLUME; ULCERATIVE COLITIS; UPREGULATION; VITAMIN METABOLISM; ANIMAL; C57BL MOUSE; CARCINOGENESIS; COLON; COLORECTAL TUMOR; IMMUNOLOGY; METABOLISM; MICROFLORA; SIGNAL TRANSDUCTION;

ANIMALS; CARCINOGENESIS; CD8-POSITIVE T-LYMPHOCYTES; COLON; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MICE; MICE, INBRED C57BL; MICROBIOTA; RETINOIC ACID 4-HYDROXYLASE; SIGNAL TRANSDUCTION; TRETINOIN; UP-REGULATION;

EID: 84990996554     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.08.008     Document Type: Article

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