ADAR1 Activation Drives Leukemia Stem Cell Self-Renewal by Impairing Let-7 Biogenesis

Cell Stem Cell

Volumn 19, Issue 2, 2016, Pages 177-191

  Zipeto, Maria Anna ^a   Court, Angela C ^a   Sadarangani, Anil ^a   Delos Santos, Nathaniel P ^a   Balaian, Larisa ^a   Chun, Hye Jung ^b   Pineda, Gabriel ^a   Morris, Sheldon R ^a   Mason, Cayla N ^a   Geron, Ifat ^a   Barrett, Christian ^c   Goff, Daniel J ^a   Wall, Russell ^a   Pellecchia, Maurizio ^d   Minden, Mark ^e   Frazer, Kelly A ^c   Marra, Marco A ^b   Crews, Leslie A ^a   Jiang, Qingfei ^a   Jamieson, Catriona H M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; ADENOSINE DEAMINASE ACTING ON RNA1; BCR ABL PROTEIN; INOSINE; JANUS KINASE 2; LENTIVIRUS VECTOR; LET 7 PROTEIN; MICRORNA; MUTANT PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG; ADAR1 PROTEIN, HUMAN; BCR-ABL1 FUSION PROTEIN, HUMAN; JAK2 PROTEIN, HUMAN; MIRNLET7 MICRORNA, HUMAN; RNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOGENESIS; BLAST CELL CRISIS; CANCER STEM CELL; CELL SELF-RENEWAL; CHRONIC MYELOID LEUKEMIA; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LEUKEMIA STEM CELL; LIN28B GENE; MOUSE; MUTAGENESIS; NEWBORN; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EDITING; RNA SEQUENCE; SIGNAL TRANSDUCTION; STROMA CELL; UPREGULATION; ANIMAL; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; PATHOLOGY;

ADENOSINE DEAMINASE; ANIMALS; BASE SEQUENCE; CELL SELF RENEWAL; FUSION PROTEINS, BCR-ABL; GENE EXPRESSION REGULATION, LEUKEMIC; JANUS KINASE 2; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICE; MICRORNAS; NEOPLASTIC STEM CELLS; RNA EDITING; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION;

EID: 84990898357     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2016.05.004     Document Type: Article

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