Glycogen synthase kinase 3β missplicing contributes to leukemia stem cell generation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 10, 2009, Pages 3925-3929

  Abrahamsson, Annelie E ^a   Geron, Ifat ^a   Gotlib, Jason ^b   Dao, Kim Hien T ^a   Barroga, Charlene F ^a   Newton, Isabel G ^a   Giles, Francis J ^c   Durocher, Jeffrey ^d   Creusot, Remi S ^b   Karimi, Mobin ^b   Jones, Carol ^b   Zehnder, James L ^b   Keating, Armand ^e   Negrin, Robert S ^b   Weissman, Irving L ^b   Jamieson, Catriona H M ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d TRANSGENOMIC INC   (United States)

^e PRINCESS MARGARET HOSPITAL   (Canada)

Author keywords

Blast crisis chronic myeloid leukemia; Cancer stem cells; Self renewal; Wnt pathway; Xenograft

Indexed keywords

APC PROTEIN; AXIN; BCR ABL PROTEIN; BETA CATENIN; CYCLIN D1; GLYCOGEN SYNTHASE KINASE 3BETA; LYMPHOID ENHANCER FACTOR 1; MYC PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOLUMINESCENCE; BLAST CELL CRISIS; CANCER STEM CELL; CELL RENEWAL; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DNA SEQUENCE; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE MUTATION; HEMATOPOIETIC STEM CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TUMOR XENOGRAFT;

ALTERNATIVE SPLICING; ANIMALS; BASE SEQUENCE; BLAST CRISIS; GLYCOGEN SYNTHASE KINASE 3; GRANULOCYTE-MACROPHAGE PROGENITOR CELLS; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MICE; MOLECULAR SEQUENCE DATA; NEOPLASTIC STEM CELLS; STEM CELL TRANSPLANTATION;

MUS;

EID: 62649139996     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0900189106     Document Type: Article

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