Bimodal antagonism of PKA signalling by ARHGAP36

Nature Communications

Volumn 7, Issue , 2016, Pages

  Eccles, Rebecca L ^a   Czajkowski, Maciej T ^a,b   Barth, Carolin ^a   Müller, Paul Markus ^a   McShane, Erik ^a   Grunwald, Stephan ^a   Beaudette, Patrick ^a   Mecklenburg, Nora ^a   Volkmer, Rudolf ^c   Zühlke, Kerstin ^a   Dittmar, Gunnar ^a   Selbach, Matthias ^a   Hammes, Annette ^a   Daumke, Oliver ^a,d   Klussmann, Enno ^a,e   Urbé, Sylvie ^f   Rocks, Oliver ^a  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b BERLIN INSTITUTE OF HEALTH   (Germany)

^c LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^d FREIE UNIVERSITÄT BERLIN   (Germany)

^e DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^f UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARHGAP36 PROTEIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; SONIC HEDGEHOG PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; RHO GTPASE-ACTIVATING PROTEIN; SMALL INTERFERING RNA;

CATALYSIS; CELL ORGANELLE; DISEASE INCIDENCE; ENZYME; ENZYME ACTIVITY; EUKARYOTE; PROTEIN;

ANIMAL CELL; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LYSOSOME; MDCK CELL LINE; NEUROBLASTOMA CELL; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; UBIQUITINATION; UPREGULATION; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CARCINOGENESIS; CEREBELLUM TUMOR; DOG; GENETICS; HEK293 CELL LINE; MEDULLOBLASTOMA; METABOLISM; MOUSE; PATHOLOGY; PHYSIOLOGY; RNA INTERFERENCE; TUMOR CELL LINE;

ERINACEIDAE; EUKARYOTA;

3T3 CELLS; ANIMALS; CARCINOGENESIS; CATALYTIC DOMAIN; CELL LINE, TUMOR; CEREBELLAR NEOPLASMS; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOGS; GTPASE-ACTIVATING PROTEINS; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; MADIN DARBY CANINE KIDNEY CELLS; MEDULLOBLASTOMA; MICE; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTEOLYSIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; UBIQUITINATION;

EID: 84990196616     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms12963     Document Type: Article

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