Effector T cell function rather than survival determines extent and duration of hepatitis in mice

Journal of Hepatology

Volumn 64, Issue 6, 2016, Pages 1327-1338

  Vo, Michelle ^a,b   Holz, Lauren E ^a,b,c   Wong, Yik Chun ^a,b   English, Kieran ^a,b   Benseler, Volker ^a,b,d   McGuffog, Claire ^a,b   Azuma, Miyuki ^e   McCaughan, Geoffrey W ^a,b   Bowen, David G ^a,b   Bertolino, Patrick ^a,b  

^a CENTENARY INSTITUTE   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF REGENSBURG   (Germany)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Autoimmunity; Liver; Tolerance; Transgenic

Indexed keywords

BIM PROTEIN; NEUTRALIZING ANTIBODY; PD L1 ANTIBODY; SUPPRESSOR OF CYTOKINE SIGNALING 1; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; BCL2L11 PROTEIN, MOUSE; CD274 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; PDCD1 PROTEIN, MOUSE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; SOCS1 PROTEIN, MOUSE;

ACUTE HEPATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SURVIVAL; CHRONIC HEPATITIS; CONTROLLED STUDY; CYTOTOXICITY; DISEASE DURATION; EFFECTOR CELL; HEPATITIS; LIVER INJURY; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ACUTE DISEASE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CYTOTOXIC T LYMPHOCYTE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; PHYSIOLOGY; TRANSGENIC MOUSE;

ACUTE DISEASE; ANIMALS; B7-H1 ANTIGEN; BCL-2-LIKE PROTEIN 11; CELL SURVIVAL; HEPATITIS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROGRAMMED CELL DEATH 1 RECEPTOR; RECEPTORS, ANTIGEN, T-CELL; SUPPRESSOR OF CYTOKINE SIGNALING 1 PROTEIN; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84962811742     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2016.01.040     Document Type: Article

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