Contribution of herpesvirus specific CD8 T cells to anti-viral T cell response in humans

PLoS Pathogens

Volumn 6, Issue 8, 2010, Pages 47-48

  Sandalova, Elena ^a   Laccabue, Diletta ^b   Boni, Carolina ^b   Tan, Anthony T ^a   Fink, Katja ^c   Ooi, Eng Eong ^d   Chua, Robert ^d   Schreve, Bahar Shafaeddin ^a,d   Ferrari, Carlo ^b   Bertoletti, Antonio ^a,d  

^a AGENCY FOR SCIENCE   (Singapore)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c AGENCY FOR SCIENCE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 15; KI 67 ANTIGEN; PROTEIN BCL 2;

ADENOVIRUS INFECTION; ADULT; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELLULAR IMMUNITY; CLINICAL ARTICLE; CYTOKINE PRODUCTION; DENGUE; EPSTEIN BARR VIRUS; HEPATITIS B; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; INFLUENZA; LYMPHOCYTE PROLIFERATION; PERSISTENT VIRUS INFECTION; PYREXIA IDIOPATHICA; T LYMPHOCYTE ACTIVATION; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MIDDLE AGED; PHENOTYPE; VIRUS INFECTION;

ADENOVIRIDAE; HEPATITIS B VIRUS; HERPESVIRIDAE; HUMAN HERPESVIRUS 4;

ADULT; CD8-POSITIVE T-LYMPHOCYTES; HERPESVIRIDAE; HUMANS; LYMPHOCYTE ACTIVATION; MIDDLE AGED; PHENOTYPE; VIRUS DISEASES; YOUNG ADULT;

EID: 77958130545     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1001051     Document Type: Article

References (39)

1. Schaub B, Lauener R, von Mutius E (2006) The many faces of the hygiene hypothesis. J Allergy Clin Immunol 117: 969-977.
2. Barton ES, White DW, Cathelyn JS, Brett-McClellan KA, Engle M, et al. (2007) Herpesvirus latency confers symbiotic protection from bacterial infection. Nature 447: 326-329.
3. Young LS, Rickinson AB (2004) Epstein-Barr virus: 40 years on. Nature Review Cancer 4: 757-768.
4. Crough T, Khanna R (2009) Immunobiology of human cytomegalovirus: from bench to bedsize. Clinical Microbiology Review 22: 76-98.
5. Wang EC, Moss PA, Frodsham P, Lehner PJ, Bell JI, et al. (1995) CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus. J Immunol 155: 5046-5056.
6. Kuijpers TW, Vossen MT, Gent M-R, Davin JC, Roos MT, et al. (2003) Frequencies of Circulating Cytolytic, CD45RA+CD27-, CD8+ T Lymphocytes Depend on Infection with CMV. JImmunol 170: 4342-4348.
7. Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, et al. (2005) Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J Exp Med 202: 673-685.
8. Kahn N, Hislop AD, Gudgeon NH, Cobbold M, Khanna R, et al. (2004) Herpesvirus-specific CD8 T cell immunity in old age: cytomegalovirus impairs the response to a coresident EBV infection. J Immunol 173: 7481-7489.
9. Tan L, Gudgeon N, Annels N, Hansasuta P, O'Callaghan C, et al. (1999) A reevaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol 162: 1827-1835.
10. Polic B, Hengel H, Krmpotic A, Trgovcich J, Pavic I, et al. (1998) Hierarchical and Redundant Lymphocyte Subset Control Precludes Cytomegalovirus Replication during Latent Infection. JExp Med 188: 1047-1054.
11. Gillespie GM, Wills MR, Appay V, O'Callaghan C, Murphy M, et al. (2000) Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors. J Virol 74: 814-824.
12. Berg RE, Crossley E, Murray S, Forman J (2003) Memory CD8+ T cells provide innate immune protection against Listeria monocytogenes in the absence of cognate antigen. J Exp Med 198: 1583-1593.
13. Miller JD, van der Most RG, Akondy RS, Glidewell JT, Albott S, et al. (2008) Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines. Immunity 28: 710-722.
14. Doisne JM, Urrutia A, Lacabaratz-Porret C, Goujard C, Meyer L, et al. (2004) CD8+ T Cells Specific for EBV, Cytomegalovirus, and Influenza Virus Are Activated during Primary HIV Infection. JImmunol 173: 2410-2418.
15. Bertoletti A, Gehring AJ (2006) The immune response during hepatitis B virus infection. J Gen Virol 87: 1439-1449.
16. Webster G, Reignat S, Maini M, Whalley S, Ogg G, et al. (2000) Incubation phase of acute Hepatitis B in man: dynamic of cellular immune mechanism. Hepatology 32: 1117-1124.
17. Clave E, Agbalika F, Bajzik V, Peffault de Latour R, Trillard M, et al. (2004) Epstein-Barr virus (EBV) reactivation in allogenic stem-cell transplantation: relationship between viral loda, EBV-specifc T cell reconstitution and rituximab therapy. Transplantation 15: 76-84.
18. Savoldo B, Goss JA, Hammer MM, Zhang L, Lopez T, et al. (2006) Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs). Blood 108: 2942-2949.
19. Dunn C, Peppa D, Khanna P, Nebbia G, Jones M, et al. (2009) Temporal Analysis of Early Immune Responses in Patients With Acute Hepatitis B Virus Infection. Gastroenterology.
20. Sprent J, Zhang X, Sun S, Tough D (2000) T-cell proliferation in vivo and the role of cytokines. Philos Trans R Soc Lond B Biol Sci 355: 317-322.
21. Liu K, Catalfamo M, Li Y, Henkart PA, Weng NP (2002) IL-15 mimics T cell receptor crosslinking in the induction of cellular proliferation, gene expression, and cytotoxicity in CD8+ memory T cells. Proc Natl Acad Sci U S A 99: 6192-6197.
22. von Geldern M, Simm B, Braun M, Weiss EH, Schendel DJ, et al. (2006) TCRindependent cytokine stimulation induces non-MHC-restricted T cell activity and is negatively regulated by HLA class I. Eur J Immunol 36: 2347-2358.
23. Xu XN, Screaton GR (2002) MHC/peptide tetramer-based studies of T cell function. J Immunol Methods 268: 21-28.
24. Boniface JJ, Rabinowitz JD, Wulfing C, Hampl J, Reich Z, et al. (1998) Initiation of signal transduction through the T cell receptor requires the mutlivalent engagment of peptide/MHC ligands. Immunity 9: 459-468.
25. Appay V, Rowland-Jones SL (2002) The assessment of antigen-specific CD8+ T cells through the combination of MHC class I tetramer and intracellular staining. J Immunol Methods 268: 9-19.
26. Tuuminen T, Kekalainen E, Makela S, Ala-Houhala I, Ennis FA, et al. (2007) Human CD8+ T cell memory generation in Puumala hantavirus infection occurs after the acute phase and is associated with boosting of EBV-specific CD8+ memory T cells. J Immunol 179: 1988-1995.
27. Papagno L, Spina CA, Marchant A, Salio M, Rufer N, et al. (2004) Immune activation and CD8+ T cell differentiation towards senescence in HIV-1 infection. PloS Biology 2: 173-185.
28. Appay V, Dunbar PR, Callan M, Klenerman P, Gillespie GM, et al. (2002) Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med 8: 379-385.
29. Weekes MP, Wills MR, Mynard K, Carmichael AJ, Sissons JG (1999) The memory cytotoxic T-lymphocyte (CTL) response to Human Cytomegalovirus Infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo. J Virol 73: 2099-2108.
30. Gamadia LE, van Leeuwen EMM, Remmerswaal EB, Yong SL, Surachno S, et al. (2004) The size and phenotype of virus-specific T cell populations is determined by repetitive antigenic stimulation and environmental cytokines. JImmunol 172: 6107-6114.
31. Karrer U, Sierro S, Wagner M, Oxenius A, Hengel H, et al. (2003) Memory inflation: continuous accumulation of antiviral CD8+ T cells over time. J Immunol 170: 2022-2029.
32. Selin L, Lin MY, Krammer KA, Pardoll D, Schneck J, et al. (1999) Attrition of T cell memory: selective loss of LCMV epitope-specific memory CD8 T cells following infections with heterologous viruses. Immunity 11: 733-742.
33. Zhang JY, Zhang Z, Jin B, Zhang SY, Zhou CB, et al. (2008) Cutting edge: programmed Death-1 up regulation is involved in the attrition of cytomegalovirus- specific CD8+ T cells in acute self-limited hepatitis B virus infection. J Immunol 181: 3741-3744.
34. van Leeuwen EM, Gamadia LE, Baars PA, Remmerswaal EB, ten Berge IJ, et al. (2002) Proliferation requirements of cytomegalovirus-specific, effector-type human CD8+ T cells. J Immunol 169: 5838-5843.
35. Jiang J, Lau LL, Shen H (2003) Selective depletion of nonspecific T cells during the early stage of immune responses to infection. J Immunol 171: 4352-4358.
36. Selin L, Varga S, Wong I, Welsh R (1998) Protective heterologous antiviral immunity and enhanced immunopathogenesis mediated by memory T cell populations. J Exp Med 188: 1705-1715.
37. Chen HD, Fraire AE, Joris I, Brehm MA, Welsh RM, et al. (2001) Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung. Nat Immunol 2: 1067-1076.
38. Welsh RM, Selin LK (2002) No one is naive: the significance of heterologous Tcell immunity. Nat Rev Immunol 2: 417-426.
39. Lai YL, Chung YK, Tan HC, Yap HF, Yap G, et al. (2007) Cost-effective Realtime reverse transcriptse (RT-PCR) to screen for dengue virus followed by rapid single-tube multiplex RT-PCR for serotyping of the virus. J Clin Microbiol 45: 935-941.