IL-15 complexes induce NK- and T-cell responses independent of type i IFN signaling during rhinovirus infection

Mucosal Immunology

Volumn 7, Issue 5, 2014, Pages 1151-1164

  Jayaraman, A ^a,b,c   Jackson, D J ^a,b,c,d   Message, S D ^a,g   Pearson, R M ^a,b,c   Aniscenko, J ^a,b,c   Caramori, G ^e   Mallia, P ^a,b,c,d   Papi, A ^e   Shamji, B ^f   Edwards, M ^f   Westwick, J ^f   Hansel, T ^a,b,c,d   Stanciu, L A ^a,b,c   Johnston, S L ^a,b,c,d   Bartlett, N W ^a,b,c  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d IMPERIAL COLLEGE HEALTHCARE NHS TRUST   (United Kingdom)

^e UNIVERSITY OF FERRARA   (Italy)

^f NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^g GLOUCESTERSHIRE ROYAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIVIRUS AGENT; CXCL9 CHEMOKINE; GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; INTERFERON RECEPTOR; INTERLEUKIN 15; INTERLEUKIN 15 INTERLEUKIN 15 RECEPTOR ALPHA COMPLEX; INTERLEUKIN 15 RECEPTOR ALPHA; UNCLASSIFIED DRUG; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; IMMUNOSTIMULATING AGENT; MESSENGER RNA;

AIRWAY NEUTROPHILIC INFLAMMATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHUS BIOPSY; BRONCHUS MUCUS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; IN VIVO STUDY; MALE; MOUSE; NATURAL KILLER CELL; NONHUMAN; NORMAL HUMAN; NOSE MUCOSA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; RESPIRATORY TRACT INFLAMMATION; RHINOVIRUS INFECTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VIRUS IMMUNITY; WILD TYPE; ANIMAL; DISEASE MODEL; IMMUNOLOGY; METABOLISM; PICORNAVIRUS INFECTION; RHINOVIRUS; SIGNAL TRANSDUCTION; UPREGULATION; CYTOKINE RESPONSE; GENE INACTIVATION; IFNGAMMA GENE; IL15 GENE; IL15RALPHA GENE; IMMUNOSTIMULATION; NEUTROPHIL; TH1 CELL; VIRUS LOAD;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; INTERFERON TYPE I; INTERLEUKIN-15; KILLER CELLS, NATURAL; MICE; PICORNAVIRIDAE INFECTIONS; RHINOVIRUS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; UP-REGULATION;

EID: 84906346840     PISSN: 19330219     EISSN: 19353456     Source Type: Journal    
DOI: 10.1038/mi.2014.2     Document Type: Article

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