메뉴 건너뛰기




Volumn 39, Issue 6, 2011, Pages 1511-1519

A murine model of hepatitis B-associated hepatocellular carcinoma generated by adeno-associated virus-mediated gene delivery

Author keywords

Adeno associated virus; Hepatitis B virus; Hepatocellular carcinoma; Mouse model

Indexed keywords

ADENO ASSOCIATED VIRUS SEROTYPE 8 VECTOR; ADENOVIRUS VECTOR; UNCLASSIFIED DRUG; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN;

EID: 80054808952     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1145     Document Type: Article
Times cited : (29)

References (49)
  • 1
    • 34250020201 scopus 로고    scopus 로고
    • Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
    • DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
    • El-Serag HB and Rudolph KL: Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576, 2007. (Pubitemid 46890874)
    • (2007) Gastroenterology , vol.132 , Issue.7 , pp. 2557-2576
    • El-Serag, H.B.1    Rudolph, K.L.2
  • 2
    • 1542316127 scopus 로고    scopus 로고
    • Hepatitis B Virus Infection - Natural History and Clinical Consequences
    • DOI 10.1056/NEJMra031087
    • Ganem D and Prince AM: Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 350: 1118-1129, 2004. (Pubitemid 38298992)
    • (2004) New England Journal of Medicine , vol.350 , Issue.11 , pp. 1118-1129
    • Ganem, D.1    Prince, A.M.2
  • 3
    • 33745547361 scopus 로고    scopus 로고
    • New therapies for hepatocellular carcinoma
    • DOI 10.1038/sj.onc.1209550, PII 1209550
    • Avila MA, Berasain C, Sangro B and Prieto J: New therapies for hepatocellular carcinoma. Oncogene 25: 3866-3884, 2006. (Pubitemid 43980482)
    • (2006) Oncogene , vol.25 , Issue.27 , pp. 3866-3884
    • Avila, M.A.1    Berasain, C.2    Sangro, B.3    Prieto, J.4
  • 4
    • 54449083925 scopus 로고    scopus 로고
    • Molecular targeted therapies in hepatocellular carcinoma
    • Llovet JM and Bruix J: Molecular targeted therapies in hepatocellular carcinoma. Hepatology 48: 1312-1327, 2008.
    • (2008) Hepatology , vol.48 , pp. 1312-1327
    • Llovet, J.M.1    Bruix, J.2
  • 5
    • 0026335594 scopus 로고
    • Chromosome deletions associated with hepatitis B virus integration
    • Tokino T, Tamura H, Hori N and Matsubara K: Chromosome deletions associated with hepatitis B virus integration. Virology 185: 879-882, 1991.
    • (1991) Virology , vol.185 , pp. 879-882
    • Tokino, T.1    Tamura, H.2    Hori, N.3    Matsubara, K.4
  • 6
    • 22644435919 scopus 로고    scopus 로고
    • Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas
    • DOI 10.1136/gut.2004.054452
    • Murakami Y, Saigo K, Takashima H, et al.: Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 54: 1162-1168, 2005. (Pubitemid 41025914)
    • (2005) Gut , vol.54 , Issue.8 , pp. 1162-1168
    • Murakami, Y.1    Saigo, K.2    Takashima, H.3    Minami, M.4    Okanoue, T.5    Brechet, C.6    Paterlini-Brechot, P.7
  • 9
    • 33645729182 scopus 로고    scopus 로고
    • Immunobiology and pathogenesis of viral hepatitis
    • Guidotti LG and Chisari FV: Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 1: 23-61, 2006.
    • (2006) Annu Rev Pathol , vol.1 , pp. 23-61
    • Guidotti, L.G.1    Chisari, F.V.2
  • 11
    • 32044433759 scopus 로고    scopus 로고
    • Animal models for the study of HBV replication and its variants
    • DOI 10.1016/S1386-6532(05)80011-3, PII S1386653205800113
    • Dandri M, Volz TK, Lutgehetmann M and Petersen J: Animal models for the study of HBV replication and its variants. J Clin Virol 34 (Suppl 1): S54-S62, 2005. (Pubitemid 43197749)
    • (2005) Journal of Clinical Virology , vol.34 , Issue.SUPPL. 1
    • Dandri, M.1    Volz, T.K.2    Lutgehetmann, M.3    Petersen, J.4
  • 12
    • 0029130068 scopus 로고
    • High-level hepatitis B virus replication in transgenic mice
    • Guidotti LG, Matzke B, Schaller H and Chisari FV: High-level hepatitis B virus replication in transgenic mice. J Virol 69: 6158-6169, 1995.
    • (1995) J Virol , vol.69 , pp. 6158-6169
    • Guidotti, L.G.1    Matzke, B.2    Schaller, H.3    Chisari, F.V.4
  • 14
    • 84983721048 scopus 로고    scopus 로고
    • An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection
    • Huang LR, Wu HL, Chen PJ and Chen DS: An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection. Proc Natl Acad Sci USA 103: 17862-17867, 2006.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 17862-17867
    • Huang, L.R.1    Wu, H.L.2    Chen, P.J.3    Chen, D.S.4
  • 17
    • 2642642141 scopus 로고    scopus 로고
    • Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
    • Xiao X, Li J and Samulski RJ: Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 72: 2224-2232, 1998. (Pubitemid 28100780)
    • (1998) Journal of Virology , vol.72 , Issue.3 , pp. 2224-2232
    • Xiao, X.1    Juan, L.I.2    Samulski, R.J.3
  • 18
    • 33748945422 scopus 로고    scopus 로고
    • The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
    • DOI 10.1128/JVI.00878-06
    • Akache B, Grimm D, Pandey K, Yant SR, Xu H and Kay MA: The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. J Virol 80: 9831-9836, 2006. (Pubitemid 44435657)
    • (2006) Journal of Virology , vol.80 , Issue.19 , pp. 9831-9836
    • Akache, B.1    Grimm, D.2    Pandey, K.3    Yant, S.R.4    Xu, H.5    Kay, M.A.6
  • 19
    • 0031691257 scopus 로고    scopus 로고
    • Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
    • Duan D, Sharma P, Yang J, et al.: Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J Virol 72: 8568-8577, 1998. (Pubitemid 28471794)
    • (1998) Journal of Virology , vol.72 , Issue.11 , pp. 8568-8577
    • Duan, D.1    Sharma, P.2    Yang, J.3    Yue, Y.4    Dudus, L.5    Zhang, Y.6    Fisher, K.J.7    Engelhardt, J.F.8
  • 21
    • 77949424429 scopus 로고    scopus 로고
    • Progress and prospects: Immune responses to viral vectors
    • Nayak S and Herzog RW: Progress and prospects: immune responses to viral vectors. Gene Ther 17: 295-304, 2010.
    • (2010) Gene Ther , vol.17 , pp. 295-304
    • Nayak, S.1    Herzog, R.W.2
  • 23
    • 70349435373 scopus 로고    scopus 로고
    • Temporal analysis of early immune responses in patients with acute hepatitis B virus infection
    • Dunn C, Peppa D, Khanna P, et al.: Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology 137: 1289-1300, 2009.
    • (2009) Gastroenterology , vol.137 , pp. 1289-1300
    • Dunn, C.1    Peppa, D.2    Khanna, P.3
  • 24
    • 13744253278 scopus 로고    scopus 로고
    • Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion method
    • Chou YC, Jeng KS, Chen ML, et al.: Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion method. J Virol 79: 1813-1823, 2005.
    • (2005) J Virol , vol.79 , pp. 1813-1823
    • Chou, Y.C.1    Jeng, K.S.2    Chen, M.L.3
  • 25
    • 33846171622 scopus 로고    scopus 로고
    • Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors
    • DOI 10.1089/hum.2006.17.1036
    • Lai Y, Yue Y, Liu M and Duan D: Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors. Hum Gene Ther 17: 1036-1042, 2006. (Pubitemid 46076745)
    • (2006) Human Gene Therapy , vol.17 , Issue.10 , pp. 1036-1042
    • Lai, Y.1    Yue, Y.2    Liu, M.3    Duan, D.4
  • 26
    • 63649148742 scopus 로고    scopus 로고
    • Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9
    • Chen CC, Sun CP, Ma HI, et al.: Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9. Mol Ther 17: 352-359, 2009.
    • (2009) Mol Ther , vol.17 , pp. 352-359
    • Chen, C.C.1    Sun, C.P.2    Ma, H.I.3
  • 27
    • 0026572225 scopus 로고
    • Hepatitis B virus replication in well differentiated mouse hepatocyte cell lines immortalized by plasmid DNA
    • Chen SH, Hu CP and Chang CM: Hepatitis B virus replication in well differentiated mouse hepatocyte cell lines immortalized by plasmid DNA. Cancer Res 52: 1329-1335, 1992.
    • (1992) Cancer Res , vol.52 , pp. 1329-1335
    • Chen, S.H.1    Hu, C.P.2    Chang, C.M.3
  • 29
    • 14944375587 scopus 로고    scopus 로고
    • Immunology of hepatitis B virus and hepatitis C virus infection
    • DOI 10.1038/nri1573
    • Rehermann B and Nascimbeni M: Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5: 215-229, 2005. (Pubitemid 40364823)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.3 , pp. 215-229
    • Rehermann, B.1    Nascimbeni, M.2
  • 33
    • 0025907983 scopus 로고
    • HBx gene of hepatitis B virus induces liver cancer in transgenic mice
    • Kim CM, Koike K, Saito I, Miyamura T and Jay G: HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 351: 317-320, 1991. (Pubitemid 21896589)
    • (1991) Nature , vol.351 , Issue.6324 , pp. 317-320
    • Kim, C.-M.1    Koike, K.2    Saito, I.3    Miyamura, T.4    Jay, G.5
  • 34
    • 33846432330 scopus 로고    scopus 로고
    • Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice
    • DOI 10.1002/hep.21445
    • Zheng Y, Chen WL, Louie SG, Yen TS and Ou JH: Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice. Hepatology 45: 16-21, 2007. (Pubitemid 46144360)
    • (2007) Hepatology , vol.45 , Issue.1 , pp. 16-21
    • Zheng, Y.1    Chen, W.-L.2    Louie, S.G.3    Yen, T.S.B.4    Ou, J.-H.J.5
  • 36
    • 0032211129 scopus 로고    scopus 로고
    • Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice
    • Shimizu Y, Guidotti LG, Fowler P and Chisari FV: Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice. J Immunol 161: 4520-4529, 1998. (Pubitemid 28492022)
    • (1998) Journal of Immunology , vol.161 , Issue.9 , pp. 4520-4529
    • Shimizu, Y.1    Guidotti, L.G.2    Fowler, P.3    Chisari, F.V.4
  • 39
    • 45349087156 scopus 로고    scopus 로고
    • Hepatitis B virus and hepatocarcinogenesis
    • Azam F and Koulaouzidis A: Hepatitis B virus and hepatocarcinogenesis. Ann Hepatol 7: 125-129, 2008. (Pubitemid 351845522)
    • (2008) Annals of Hepatology , vol.7 , Issue.2 , pp. 125-129
    • Azam, F.1    Koulaouzidis, A.2
  • 40
    • 0028916425 scopus 로고
    • Hepatitis B virus immunopathogenesis
    • Chisari FV and Ferrari C: Hepatitis B virus immunopathogenesis. Annu Rev Immunol 13: 29-60, 1995.
    • (1995) Annu Rev Immunol , vol.13 , pp. 29-60
    • Chisari, F.V.1    Ferrari, C.2
  • 41
    • 0038054338 scopus 로고    scopus 로고
    • AAV serotype 2 vectors preferentially integrate into active genes in mice
    • DOI 10.1038/ng1179
    • Nakai H, Montini E, Fuess S, Storm TA, Grompe M and Kay MA: AAV serotype 2 vectors preferentially integrate into active genes in mice. Nat Genet 34: 297-302, 2003. (Pubitemid 36792862)
    • (2003) Nature Genetics , vol.34 , Issue.3 , pp. 297-302
    • Nakai, H.1    Montini, E.2    Fuess, S.3    Storm, T.A.4    Grompe, M.5    Kay, M.A.6
  • 42
    • 3042728872 scopus 로고    scopus 로고
    • Adeno-associated virus vectors integrate at chromosome breakage sites
    • DOI 10.1038/ng1380
    • Miller DG, Petek LM and Russell DW: Adeno-associated virus vectors integrate at chromosome breakage sites. Nat Genet 36: 767-773, 2004. (Pubitemid 38886641)
    • (2004) Nature Genetics , vol.36 , Issue.7 , pp. 767-773
    • Miller, D.G.1    Petek, L.M.2    Russell, D.W.3
  • 45
    • 79953088521 scopus 로고    scopus 로고
    • Assessing the potential for AAV vector genotoxicity in a murine model
    • Li H, Malani N, Hamilton SR, et al.: Assessing the potential for AAV vector genotoxicity in a murine model. Blood 117: 3311-3319, 2011.
    • (2011) Blood , vol.117 , pp. 3311-3319
    • Li, H.1    Malani, N.2    Hamilton, S.R.3
  • 49
    • 62149116794 scopus 로고    scopus 로고
    • A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma
    • Keng VW, Villanueva A, Chiang DY, et al.: A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nat Biotechnol 27: 264-274, 2009.
    • (2009) Nat Biotechnol , vol.27 , pp. 264-274
    • Keng, V.W.1    Villanueva, A.2    Chiang, D.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.