-
1
-
-
34250020201
-
Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis
-
DOI 10.1053/j.gastro.2007.04.061, PII S0016508507007998
-
El-Serag HB and Rudolph KL: Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576, 2007. (Pubitemid 46890874)
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2557-2576
-
-
El-Serag, H.B.1
Rudolph, K.L.2
-
2
-
-
1542316127
-
Hepatitis B Virus Infection - Natural History and Clinical Consequences
-
DOI 10.1056/NEJMra031087
-
Ganem D and Prince AM: Hepatitis B virus infection-natural history and clinical consequences. N Engl J Med 350: 1118-1129, 2004. (Pubitemid 38298992)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.11
, pp. 1118-1129
-
-
Ganem, D.1
Prince, A.M.2
-
3
-
-
33745547361
-
New therapies for hepatocellular carcinoma
-
DOI 10.1038/sj.onc.1209550, PII 1209550
-
Avila MA, Berasain C, Sangro B and Prieto J: New therapies for hepatocellular carcinoma. Oncogene 25: 3866-3884, 2006. (Pubitemid 43980482)
-
(2006)
Oncogene
, vol.25
, Issue.27
, pp. 3866-3884
-
-
Avila, M.A.1
Berasain, C.2
Sangro, B.3
Prieto, J.4
-
4
-
-
54449083925
-
Molecular targeted therapies in hepatocellular carcinoma
-
Llovet JM and Bruix J: Molecular targeted therapies in hepatocellular carcinoma. Hepatology 48: 1312-1327, 2008.
-
(2008)
Hepatology
, vol.48
, pp. 1312-1327
-
-
Llovet, J.M.1
Bruix, J.2
-
5
-
-
0026335594
-
Chromosome deletions associated with hepatitis B virus integration
-
Tokino T, Tamura H, Hori N and Matsubara K: Chromosome deletions associated with hepatitis B virus integration. Virology 185: 879-882, 1991.
-
(1991)
Virology
, vol.185
, pp. 879-882
-
-
Tokino, T.1
Tamura, H.2
Hori, N.3
Matsubara, K.4
-
6
-
-
22644435919
-
Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas
-
DOI 10.1136/gut.2004.054452
-
Murakami Y, Saigo K, Takashima H, et al.: Large scaled analysis of hepatitis B virus (HBV) DNA integration in HBV related hepatocellular carcinomas. Gut 54: 1162-1168, 2005. (Pubitemid 41025914)
-
(2005)
Gut
, vol.54
, Issue.8
, pp. 1162-1168
-
-
Murakami, Y.1
Saigo, K.2
Takashima, H.3
Minami, M.4
Okanoue, T.5
Brechet, C.6
Paterlini-Brechot, P.7
-
7
-
-
33750427850
-
Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma
-
DOI 10.1016/j.jhep.2006.07.025, PII S0168827806004557
-
Muroyama R, Kato N, Yoshida H, et al.: Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma. J Hepatol 45: 805-812, 2006. (Pubitemid 44646684)
-
(2006)
Journal of Hepatology
, vol.45
, Issue.6
, pp. 805-812
-
-
Muroyama, R.1
Kato, N.2
Yoshida, H.3
Otsuka, M.4
Moriyama, M.5
Wang, Y.6
Shao, R.-X.7
Dharel, N.8
Tanaka, Y.9
Ohta, M.10
Tateishi, R.11
Shiina, S.12
Tatsukawa, M.13
Fukai, K.14
Imazeki, F.15
Yokosuka, O.16
Shiratori, Y.17
Omata, M.18
-
9
-
-
33645729182
-
Immunobiology and pathogenesis of viral hepatitis
-
Guidotti LG and Chisari FV: Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol 1: 23-61, 2006.
-
(2006)
Annu Rev Pathol
, vol.1
, pp. 23-61
-
-
Guidotti, L.G.1
Chisari, F.V.2
-
10
-
-
0019131868
-
Chronic hepatitis in chimpanzee carriers of hepatitis B virus: Morphologic, immunologic, and viral DNA studies
-
DOI 10.1073/pnas.77.10.6147
-
Shouval D, Chakraborty PR, Ruiz-Opazo N, et al.: Chronic hepatitis in chimpanzee carriers of hepatitis B virus: morphologic, immunologic, and viral DNA studies. Proc Natl Acad Sci USA 77: 6147-6151, 1980. (Pubitemid 11206359)
-
(1980)
Proceedings of the National Academy of Sciences of the United States of America
, vol.77
, Issue.10 II
, pp. 6147-6151
-
-
Shouval, D.1
Chakraborty, P.R.2
Ruiz-Opazo, N.3
-
11
-
-
32044433759
-
Animal models for the study of HBV replication and its variants
-
DOI 10.1016/S1386-6532(05)80011-3, PII S1386653205800113
-
Dandri M, Volz TK, Lutgehetmann M and Petersen J: Animal models for the study of HBV replication and its variants. J Clin Virol 34 (Suppl 1): S54-S62, 2005. (Pubitemid 43197749)
-
(2005)
Journal of Clinical Virology
, vol.34
, Issue.SUPPL. 1
-
-
Dandri, M.1
Volz, T.K.2
Lutgehetmann, M.3
Petersen, J.4
-
12
-
-
0029130068
-
High-level hepatitis B virus replication in transgenic mice
-
Guidotti LG, Matzke B, Schaller H and Chisari FV: High-level hepatitis B virus replication in transgenic mice. J Virol 69: 6158-6169, 1995.
-
(1995)
J Virol
, vol.69
, pp. 6158-6169
-
-
Guidotti, L.G.1
Matzke, B.2
Schaller, H.3
Chisari, F.V.4
-
13
-
-
0037108818
-
Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection
-
DOI 10.1073/pnas.202398599
-
Yang PL, Althage A, Chung J and Chisari FV: Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proc Natl Acad Sci USA 99: 13825-13830, 2002. (Pubitemid 35215465)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.21
, pp. 13825-13830
-
-
Yang, P.L.1
Althage, A.2
Chung, J.3
Chisari, F.V.4
-
14
-
-
84983721048
-
An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection
-
Huang LR, Wu HL, Chen PJ and Chen DS: An immunocompetent mouse model for the tolerance of human chronic hepatitis B virus infection. Proc Natl Acad Sci USA 103: 17862-17867, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17862-17867
-
-
Huang, L.R.1
Wu, H.L.2
Chen, P.J.3
Chen, D.S.4
-
15
-
-
0032815287
-
Hepatitis B virus transgenic mouse model of chronic liver disease
-
DOI 10.1038/11347
-
Larkin J, Clayton M, Sun B, et al.: Hepatitis B virus transgenic mouse model of chronic liver disease. Nat Med 5: 907-912, 1999. (Pubitemid 29372417)
-
(1999)
Nature Medicine
, vol.5
, Issue.8
, pp. 907-912
-
-
Larkin, J.1
Clayton, M.2
Sun, B.3
Perchonock, C.E.4
Morgan, J.L.5
Siracusa, L.D.6
Michaels, F.H.7
Feitelson, M.A.8
-
16
-
-
0037015049
-
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy
-
DOI 10.1073/pnas.182412299
-
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J and Wilson JM: Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy. Proc Natl Acad Sci USA 99: 11854-11859, 2002. (Pubitemid 34994488)
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, Issue.18
, pp. 11854-11859
-
-
Gao, G.-P.1
Alvira, M.R.2
Wang, L.3
Calcedo, R.4
Johnston, J.5
Wilson, J.M.6
-
17
-
-
2642642141
-
Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus
-
Xiao X, Li J and Samulski RJ: Production of high-titer recombinant adeno-associated virus vectors in the absence of helper adenovirus. J Virol 72: 2224-2232, 1998. (Pubitemid 28100780)
-
(1998)
Journal of Virology
, vol.72
, Issue.3
, pp. 2224-2232
-
-
Xiao, X.1
Juan, L.I.2
Samulski, R.J.3
-
18
-
-
33748945422
-
The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9
-
DOI 10.1128/JVI.00878-06
-
Akache B, Grimm D, Pandey K, Yant SR, Xu H and Kay MA: The 37/67-kilodalton laminin receptor is a receptor for adeno-associated virus serotypes 8, 2, 3, and 9. J Virol 80: 9831-9836, 2006. (Pubitemid 44435657)
-
(2006)
Journal of Virology
, vol.80
, Issue.19
, pp. 9831-9836
-
-
Akache, B.1
Grimm, D.2
Pandey, K.3
Yant, S.R.4
Xu, H.5
Kay, M.A.6
-
19
-
-
0031691257
-
Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue
-
Duan D, Sharma P, Yang J, et al.: Circular intermediates of recombinant adeno-associated virus have defined structural characteristics responsible for long-term episomal persistence in muscle tissue. J Virol 72: 8568-8577, 1998. (Pubitemid 28471794)
-
(1998)
Journal of Virology
, vol.72
, Issue.11
, pp. 8568-8577
-
-
Duan, D.1
Sharma, P.2
Yang, J.3
Yue, Y.4
Dudus, L.5
Zhang, Y.6
Fisher, K.J.7
Engelhardt, J.F.8
-
20
-
-
42549161844
-
The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver
-
DOI 10.1038/mt.2008.37, PII MT200837
-
McCaffrey AP, Fawcett P, Nakai H, et al.: The host response to adenovirus, helper-dependent adenovirus, and adeno-associated virus in mouse liver. Mol Ther 16: 931-941, 2008. (Pubitemid 351587104)
-
(2008)
Molecular Therapy
, vol.16
, Issue.5
, pp. 931-941
-
-
McCaffrey, A.P.1
Fawcett, P.2
Nakai, H.3
McCaffrey, R.L.4
Ehrhardt, A.5
Pham, T.-T.T.6
Pandey, K.7
Xu, H.8
Feuss, S.9
Storm, T.A.10
Kay, M.A.11
-
21
-
-
77949424429
-
Progress and prospects: Immune responses to viral vectors
-
Nayak S and Herzog RW: Progress and prospects: immune responses to viral vectors. Gene Ther 17: 295-304, 2010.
-
(2010)
Gene Ther
, vol.17
, pp. 295-304
-
-
Nayak, S.1
Herzog, R.W.2
-
22
-
-
2342588229
-
Genomic analysis of the host response to hepatitis B virus infection
-
DOI 10.1073/pnas.0401771101
-
Wieland S, Thimme R, Purcell RH and Chisari FV: Genomic analysis of the host response to hepatitis B virus infection. Proc Natl Acad Sci USA 101: 6669-6674, 2004. (Pubitemid 38586032)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.17
, pp. 6669-6674
-
-
Wieland, S.1
Thimme, R.2
Purcell, R.H.3
Chisari, F.V.4
-
23
-
-
70349435373
-
Temporal analysis of early immune responses in patients with acute hepatitis B virus infection
-
Dunn C, Peppa D, Khanna P, et al.: Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. Gastroenterology 137: 1289-1300, 2009.
-
(2009)
Gastroenterology
, vol.137
, pp. 1289-1300
-
-
Dunn, C.1
Peppa, D.2
Khanna, P.3
-
24
-
-
13744253278
-
Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion method
-
Chou YC, Jeng KS, Chen ML, et al.: Evaluation of transcriptional efficiency of hepatitis B virus covalently closed circular DNA by reverse transcription-PCR combined with the restriction enzyme digestion method. J Virol 79: 1813-1823, 2005.
-
(2005)
J Virol
, vol.79
, pp. 1813-1823
-
-
Chou, Y.C.1
Jeng, K.S.2
Chen, M.L.3
-
25
-
-
33846171622
-
Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors
-
DOI 10.1089/hum.2006.17.1036
-
Lai Y, Yue Y, Liu M and Duan D: Synthetic intron improves transduction efficiency of trans-splicing adeno-associated viral vectors. Hum Gene Ther 17: 1036-1042, 2006. (Pubitemid 46076745)
-
(2006)
Human Gene Therapy
, vol.17
, Issue.10
, pp. 1036-1042
-
-
Lai, Y.1
Yue, Y.2
Liu, M.3
Duan, D.4
-
26
-
-
63649148742
-
Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9
-
Chen CC, Sun CP, Ma HI, et al.: Comparative study of anti-hepatitis B virus RNA interference by double-stranded adeno-associated virus serotypes 7, 8, and 9. Mol Ther 17: 352-359, 2009.
-
(2009)
Mol Ther
, vol.17
, pp. 352-359
-
-
Chen, C.C.1
Sun, C.P.2
Ma, H.I.3
-
27
-
-
0026572225
-
Hepatitis B virus replication in well differentiated mouse hepatocyte cell lines immortalized by plasmid DNA
-
Chen SH, Hu CP and Chang CM: Hepatitis B virus replication in well differentiated mouse hepatocyte cell lines immortalized by plasmid DNA. Cancer Res 52: 1329-1335, 1992.
-
(1992)
Cancer Res
, vol.52
, pp. 1329-1335
-
-
Chen, S.H.1
Hu, C.P.2
Chang, C.M.3
-
28
-
-
27944479711
-
Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors
-
DOI 10.1038/nbt1153, PII N1153
-
Lai Y, Yue Y, Liu M, et al.: Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors. Nat Biotechnol 23: 1435-1439, 2005. (Pubitemid 41679397)
-
(2005)
Nature Biotechnology
, vol.23
, Issue.11
, pp. 1435-1439
-
-
Lai, Y.1
Yue, Y.2
Liu, M.3
Ghosh, A.4
Engelhardt, J.F.5
Chamberlain, J.S.6
Duan, D.7
-
29
-
-
14944375587
-
Immunology of hepatitis B virus and hepatitis C virus infection
-
DOI 10.1038/nri1573
-
Rehermann B and Nascimbeni M: Immunology of hepatitis B virus and hepatitis C virus infection. Nat Rev Immunol 5: 215-229, 2005. (Pubitemid 40364823)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.3
, pp. 215-229
-
-
Rehermann, B.1
Nascimbeni, M.2
-
30
-
-
0034303937
-
Pale bodies in hepatocellular carcinoma
-
Moon WS, Yu HC, Chung MJ, Kang MJ and Lee DG: Pale bodies in hepatocellular carcinoma. J Korean Med Sci 15: 516-520, 2000.
-
(2000)
J Korean Med Sci
, vol.15
, pp. 516-520
-
-
Moon, W.S.1
Yu, H.C.2
Chung, M.J.3
Kang, M.J.4
Lee, D.G.5
-
31
-
-
0026674721
-
Pathomorphologic study of pale bodies in hepatocellular carcinoma
-
Nakashima O, Sugihara S, Eguchi A, Taguchi J, Watanabe J and Kojiro M: Pathomorphologic study of pale bodies in hepatocellular carcinoma. Acta Pathol Jpn 42: 414-418, 1992.
-
(1992)
Acta Pathol Jpn
, vol.42
, pp. 414-418
-
-
Nakashima, O.1
Sugihara, S.2
Eguchi, A.3
Taguchi, J.4
Watanabe, J.5
Kojiro, M.6
-
32
-
-
0024818649
-
Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice
-
DOI 10.1016/0092-8674(89)90770-8
-
Chisari FV, Klopchin K, Moriyama T, et al.: Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell 59: 1145-1156, 1989. (Pubitemid 20024625)
-
(1989)
Cell
, vol.59
, Issue.6
, pp. 1145-1156
-
-
Chisari, F.V.1
Klopchin, K.2
Moriyama, T.3
Pasquinelli, C.4
Dunsford, H.A.5
Sell, S.6
Pinkert, C.A.7
Brinster, R.L.8
Palmiter, R.D.9
-
33
-
-
0025907983
-
HBx gene of hepatitis B virus induces liver cancer in transgenic mice
-
Kim CM, Koike K, Saito I, Miyamura T and Jay G: HBx gene of hepatitis B virus induces liver cancer in transgenic mice. Nature 351: 317-320, 1991. (Pubitemid 21896589)
-
(1991)
Nature
, vol.351
, Issue.6324
, pp. 317-320
-
-
Kim, C.-M.1
Koike, K.2
Saito, I.3
Miyamura, T.4
Jay, G.5
-
34
-
-
33846432330
-
Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice
-
DOI 10.1002/hep.21445
-
Zheng Y, Chen WL, Louie SG, Yen TS and Ou JH: Hepatitis B virus promotes hepatocarcinogenesis in transgenic mice. Hepatology 45: 16-21, 2007. (Pubitemid 46144360)
-
(2007)
Hepatology
, vol.45
, Issue.1
, pp. 16-21
-
-
Zheng, Y.1
Chen, W.-L.2
Louie, S.G.3
Yen, T.S.B.4
Ou, J.-H.J.5
-
35
-
-
0035863924
-
Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice
-
Sette AD, Oseroff C, Sidney J, et al.: Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice. J Immunol 166: 1389-1397, 2001. (Pubitemid 32060302)
-
(2001)
Journal of Immunology
, vol.166
, Issue.2
, pp. 1389-1397
-
-
Sette, A.D.1
Oseroff, C.2
Sidney, J.3
Alexander, J.4
Chesnut, R.W.5
Kakimi, K.6
Guidotti, L.G.7
Chisari, F.V.8
-
36
-
-
0032211129
-
Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice
-
Shimizu Y, Guidotti LG, Fowler P and Chisari FV: Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice. J Immunol 161: 4520-4529, 1998. (Pubitemid 28492022)
-
(1998)
Journal of Immunology
, vol.161
, Issue.9
, pp. 4520-4529
-
-
Shimizu, Y.1
Guidotti, L.G.2
Fowler, P.3
Chisari, F.V.4
-
37
-
-
0031872341
-
Immune pathogenesis of hepatocellular carcinoma
-
DOI 10.1084/jem.188.2.341
-
Nakamoto Y, Guidotti LG, Kuhlen CV, Fowler P and Chisari FV: Immune pathogenesis of hepatocellular carcinoma. J Exp Med 188: 341-350, 1998. (Pubitemid 28357762)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.2
, pp. 341-350
-
-
Nakamoto, Y.1
Guidotti, L.G.2
Kuhlen, C.V.3
Fowler, P.4
Chisari, F.V.5
-
38
-
-
29944436855
-
Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA Level
-
DOI 10.1001/jama.295.1.65
-
Chen CJ, Yang HI, Su J, et al.: Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 295: 65-73, 2006. (Pubitemid 43042691)
-
(2006)
Journal of the American Medical Association
, vol.295
, Issue.1
, pp. 65-73
-
-
Chen, C.-J.1
Yang, H.-I.2
Su, J.3
Jen, C.-L.4
You, S.-L.5
Lu, S.-N.6
Huang, G.-T.7
Iloeje, U.H.8
-
39
-
-
45349087156
-
Hepatitis B virus and hepatocarcinogenesis
-
Azam F and Koulaouzidis A: Hepatitis B virus and hepatocarcinogenesis. Ann Hepatol 7: 125-129, 2008. (Pubitemid 351845522)
-
(2008)
Annals of Hepatology
, vol.7
, Issue.2
, pp. 125-129
-
-
Azam, F.1
Koulaouzidis, A.2
-
40
-
-
0028916425
-
Hepatitis B virus immunopathogenesis
-
Chisari FV and Ferrari C: Hepatitis B virus immunopathogenesis. Annu Rev Immunol 13: 29-60, 1995.
-
(1995)
Annu Rev Immunol
, vol.13
, pp. 29-60
-
-
Chisari, F.V.1
Ferrari, C.2
-
41
-
-
0038054338
-
AAV serotype 2 vectors preferentially integrate into active genes in mice
-
DOI 10.1038/ng1179
-
Nakai H, Montini E, Fuess S, Storm TA, Grompe M and Kay MA: AAV serotype 2 vectors preferentially integrate into active genes in mice. Nat Genet 34: 297-302, 2003. (Pubitemid 36792862)
-
(2003)
Nature Genetics
, vol.34
, Issue.3
, pp. 297-302
-
-
Nakai, H.1
Montini, E.2
Fuess, S.3
Storm, T.A.4
Grompe, M.5
Kay, M.A.6
-
42
-
-
3042728872
-
Adeno-associated virus vectors integrate at chromosome breakage sites
-
DOI 10.1038/ng1380
-
Miller DG, Petek LM and Russell DW: Adeno-associated virus vectors integrate at chromosome breakage sites. Nat Genet 36: 767-773, 2004. (Pubitemid 38886641)
-
(2004)
Nature Genetics
, vol.36
, Issue.7
, pp. 767-773
-
-
Miller, D.G.1
Petek, L.M.2
Russell, D.W.3
-
43
-
-
33745250487
-
Analysis of Tumors Arising in Male B6C3F1 Mice with and without AAV Vector Delivery to Liver
-
DOI 10.1016/j.ymthe.2006.03.008, PII S1525001606000918
-
Bell P, Moscioni AD, McCarter RJ, et al.: Analysis of tumors arising in male B6C3F1 mice with and without AAV vector delivery to liver. Mol Ther 14: 34-44, 2006. (Pubitemid 43922140)
-
(2006)
Molecular Therapy
, vol.14
, Issue.1
, pp. 34-44
-
-
Bell, P.1
Moscioni, A.D.2
McCarter, R.J.3
Wu, D.4
Gao, G.5
Hoang, A.6
Sanmiguel, J.C.7
Sun, X.8
Wivel, N.A.9
Raper, S.E.10
Furth, E.E.11
Batshaw, M.L.12
Wilson, J.M.13
-
44
-
-
22644433751
-
No evidence for tumorigenesis of AAV vectors in a large-scale study in mice
-
DOI 10.1016/j.ymthe.2005.03.020, PII S1525001605001449
-
Bell P, Wang L, Lebherz C, et al.: No evidence for tumorigenesis of AAV vectors in a large-scale study in mice. Mol Ther 12: 299-306, 2005. (Pubitemid 41025100)
-
(2005)
Molecular Therapy
, vol.12
, Issue.2
, pp. 299-306
-
-
Bell, P.1
Wang, L.2
Lebherz, C.3
Flieder, D.B.4
Bove, M.S.5
Wu, D.6
Gao, G.P.7
Wilson, J.M.8
Wivel, N.A.9
-
45
-
-
79953088521
-
Assessing the potential for AAV vector genotoxicity in a murine model
-
Li H, Malani N, Hamilton SR, et al.: Assessing the potential for AAV vector genotoxicity in a murine model. Blood 117: 3311-3319, 2011.
-
(2011)
Blood
, vol.117
, pp. 3311-3319
-
-
Li, H.1
Malani, N.2
Hamilton, S.R.3
-
46
-
-
34547610960
-
AAV vector integration sites in mouse hepatocellular carcinoma
-
DOI 10.1126/science.1142658
-
Donsante A, Miller DG, Li Y, et al.: AAV vector integration sites in mouse hepatocellular carcinoma. Science 317: 477, 2007. (Pubitemid 47196106)
-
(2007)
Science
, vol.317
, Issue.5837
, pp. 477
-
-
Donsante, A.1
Miller, D.G.2
Li, Y.3
Vogler, C.4
Brunt, E.M.5
Russell, D.W.6
Sands, M.S.7
-
47
-
-
0034830365
-
Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors
-
DOI 10.1038/sj.gt.3301541
-
Donsante A, Vogler C, Muzyczka N, et al.: Observed incidence of tumorigenesis in long-term rodent studies of rAAV vectors. Gene Ther 8: 1343-1346, 2001. (Pubitemid 32834303)
-
(2001)
Gene Therapy
, vol.8
, Issue.17
, pp. 1343-1346
-
-
Donsante, A.1
Vogler, C.2
Muzyczka, N.3
Crawford, J.M.4
Barker, J.5
Flotte, T.6
Campbell-Thompson, M.7
Daly, T.8
Sands, M.S.9
-
48
-
-
41249102034
-
Experimental models of hepatocellular carcinoma
-
Newell P, Villanueva A, Friedman SL, Koike K and Llovet JM: Experimental models of hepatocellular carcinoma. J Hepatol 48: 858-879, 2008.
-
(2008)
J Hepatol
, vol.48
, pp. 858-879
-
-
Newell, P.1
Villanueva, A.2
Friedman, S.L.3
Koike, K.4
Llovet, J.M.5
-
49
-
-
62149116794
-
A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma
-
Keng VW, Villanueva A, Chiang DY, et al.: A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma. Nat Biotechnol 27: 264-274, 2009.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 264-274
-
-
Keng, V.W.1
Villanueva, A.2
Chiang, D.Y.3
|