-
1
-
-
84884860377
-
Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes
-
[1] Birkenfeld, A.L., Shulman, G.I., Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 diabetes. Hepatology 59 (2014), 713–723.
-
(2014)
Hepatology
, vol.59
, pp. 713-723
-
-
Birkenfeld, A.L.1
Shulman, G.I.2
-
2
-
-
84874741669
-
Diabetes and nonalcoholic fatty liver disease: a pathogenic duo
-
[2] Williams, K.H., Shackel, N.A., Gorrell, M.D., McLennan, S.V., Twigg, S.M., Diabetes and nonalcoholic fatty liver disease: a pathogenic duo. Endocr. Rev. 34 (2013), 84–129.
-
(2013)
Endocr. Rev.
, vol.34
, pp. 84-129
-
-
Williams, K.H.1
Shackel, N.A.2
Gorrell, M.D.3
McLennan, S.V.4
Twigg, S.M.5
-
3
-
-
84879905328
-
Potential of incretin-based therapies for non-alcoholic fatty liver disease
-
[3] Samson, S.L., Bajaj, M., Potential of incretin-based therapies for non-alcoholic fatty liver disease. J. Diabetes Complicat. 27 (2013), 401–406.
-
(2013)
J. Diabetes Complicat.
, vol.27
, pp. 401-406
-
-
Samson, S.L.1
Bajaj, M.2
-
4
-
-
73549103572
-
Glucose enhances expression of TRPC1 and calcium entry in endothelial cells
-
[4] Bishara, N.B., Ding, H., Glucose enhances expression of TRPC1 and calcium entry in endothelial cells. Am. J. Physiol. Heart Circ. Physiol. 298 (2010), H171–H178.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.298
, pp. H171-H178
-
-
Bishara, N.B.1
Ding, H.2
-
5
-
-
84878808238
-
Pharmacology, physiology, and mechanisms of incretin hormone action
-
[5] Campbell, J.E., Drucker, D.J., Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab. 17 (2013), 819–837.
-
(2013)
Cell Metab.
, vol.17
, pp. 819-837
-
-
Campbell, J.E.1
Drucker, D.J.2
-
6
-
-
84905397741
-
Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease
-
[6] Liu, Y., Wei, R., Hong, T.P., Potential roles of glucagon-like peptide-1-based therapies in treating non-alcoholic fatty liver disease. World J. Gastroenterol. 20 (2014), 9090–9097.
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 9090-9097
-
-
Liu, Y.1
Wei, R.2
Hong, T.P.3
-
7
-
-
84940721655
-
Calcium homeostasis and organelle function in the pathogenesis of obesity and diabetes
-
[7] Arruda, A.P., Hotamisligil, G.S., Calcium homeostasis and organelle function in the pathogenesis of obesity and diabetes. Cell Metab. 22 (2015), 381–397.
-
(2015)
Cell Metab.
, vol.22
, pp. 381-397
-
-
Arruda, A.P.1
Hotamisligil, G.S.2
-
8
-
-
84901944641
-
The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes
-
[8] Perry, R.J., Samuel, V.T., Petersen, K.F., Shulman, G.I., The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes. Nature 510 (2014), 84–91.
-
(2014)
Nature
, vol.510
, pp. 84-91
-
-
Perry, R.J.1
Samuel, V.T.2
Petersen, K.F.3
Shulman, G.I.4
-
9
-
-
84902332964
-
Calcium-dependent regulation of glucose homeostasis in the liver
-
[9] Bartlett, P.J., Gaspers, L.D., Pierobon, N., Thomas, A.P., Calcium-dependent regulation of glucose homeostasis in the liver. Cell Calcium 55 (2014), 306–316.
-
(2014)
Cell Calcium
, vol.55
, pp. 306-316
-
-
Bartlett, P.J.1
Gaspers, L.D.2
Pierobon, N.3
Thomas, A.P.4
-
10
-
-
84873178604
-
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
-
[10] Cantley, J.L., Yoshimura, T., Camporez, J.P., Zhang, D., Jornayvaz, F.R., Kumashiro, N., Guebre-Egziabher, F., Jurczak, M.J., Kahn, M., Guigni, B.A., Serr, J., Hankin, J., Murphy, R.C., Cline, G.W., Bhanot, S., Manchem, V.P., Brown, J.M., Samuel, V.T., Shulman, G.I., CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 110 (2013), 1869–1874.
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 1869-1874
-
-
Cantley, J.L.1
Yoshimura, T.2
Camporez, J.P.3
Zhang, D.4
Jornayvaz, F.R.5
Kumashiro, N.6
Guebre-Egziabher, F.7
Jurczak, M.J.8
Kahn, M.9
Guigni, B.A.10
Serr, J.11
Hankin, J.12
Murphy, R.C.13
Cline, G.W.14
Bhanot, S.15
Manchem, V.P.16
Brown, J.M.17
Samuel, V.T.18
Shulman, G.I.19
-
11
-
-
79957605136
-
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
-
[11] Fu, S., Yang, L., Li, P., Hofmann, O., Dicker, L., Hide, W., Lin, X., Watkins, S.M., Ivanov, A.R., Hotamisligil, G.S., Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature 473 (2011), 528–531.
-
(2011)
Nature
, vol.473
, pp. 528-531
-
-
Fu, S.1
Yang, L.2
Li, P.3
Hofmann, O.4
Dicker, L.5
Hide, W.6
Lin, X.7
Watkins, S.M.8
Ivanov, A.R.9
Hotamisligil, G.S.10
-
12
-
-
84902661992
-
Incretin based therapies: a novel treatment approach for non-alcoholic fatty liver disease
-
[12] Blaslov, K., Bulum, T., Zibar, K., Duvnjak, L., Incretin based therapies: a novel treatment approach for non-alcoholic fatty liver disease. World J. Gastroenterol. 20 (2014), 7356–7365.
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 7356-7365
-
-
Blaslov, K.1
Bulum, T.2
Zibar, K.3
Duvnjak, L.4
-
13
-
-
84875985453
-
Glucagon-like peptides 1 and 2 in health and disease: a review
-
[13] Marathe, C.S., Rayner, C.K., Jones, K.L., Horowitz, M., Glucagon-like peptides 1 and 2 in health and disease: a review. Peptides 44 (2013), 75–86.
-
(2013)
Peptides
, vol.44
, pp. 75-86
-
-
Marathe, C.S.1
Rayner, C.K.2
Jones, K.L.3
Horowitz, M.4
-
14
-
-
79955627418
-
Thermogenesis and related metabolic targets in anti-diabetic therapy
-
[14] Arch, J.R., Thermogenesis and related metabolic targets in anti-diabetic therapy. Handb. Exp. Pharmacol., 2011, 201–255.
-
(2011)
Handb. Exp. Pharmacol.
, pp. 201-255
-
-
Arch, J.R.1
-
15
-
-
84910603708
-
Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation
-
[15] Wang, X.C., Gusdon, A.M., Liu, H., Qu, S., Effects of glucagon-like peptide-1 receptor agonists on non-alcoholic fatty liver disease and inflammation. World J. Gastroenterol. 20 (2014), 14821–14830.
-
(2014)
World J. Gastroenterol.
, vol.20
, pp. 14821-14830
-
-
Wang, X.C.1
Gusdon, A.M.2
Liu, H.3
Qu, S.4
-
16
-
-
84857185142
-
Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice
-
[16] Lee, J., Hong, S.W., Chae, S.W., Kim, D.H., Choi, J.H., Bae, J.C., Park, S.E., Rhee, E.J., Park, C.Y., Oh, K.W., Park, S.W., Kim, S.W., Lee, W.Y., Exendin-4 improves steatohepatitis by increasing Sirt1 expression in high-fat diet-induced obese C57BL/6J mice. PLoS One, 7, 2012, e31394.
-
(2012)
PLoS One
, vol.7
, pp. e31394
-
-
Lee, J.1
Hong, S.W.2
Chae, S.W.3
Kim, D.H.4
Choi, J.H.5
Bae, J.C.6
Park, S.E.7
Rhee, E.J.8
Park, C.Y.9
Oh, K.W.10
Park, S.W.11
Kim, S.W.12
Lee, W.Y.13
-
17
-
-
84923253501
-
2 + through a protein kinase C-dependent mechanism
-
2 + through a protein kinase C-dependent mechanism. Biochem. J. 466 (2015), 379–390.
-
(2015)
Biochem. J.
, vol.466
, pp. 379-390
-
-
Wilson, C.H.1
Ali, E.S.2
Scrimgeour, N.3
Martin, A.M.4
Hua, J.5
Tallis, G.A.6
Rychkov, G.Y.7
Barritt, G.J.8
-
18
-
-
41949095679
-
2 + -permeable channels in the hepatocyte plasma membrane and their roles in hepatocyte physiology
-
2 + -permeable channels in the hepatocyte plasma membrane and their roles in hepatocyte physiology. Biochim. Biophys. Acta 1783 (2008), 651–672.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 651-672
-
-
Barritt, G.J.1
Chen, J.2
Rychkov, G.Y.3
-
21
-
-
0021923858
-
Nile red: a selective fluorescent stain for intracellular lipid droplets
-
[21] Greenspan, P., Mayer, E.P., Fowler, S.D., Nile red: a selective fluorescent stain for intracellular lipid droplets. J. Cell Biol. 100 (1985), 965–973.
-
(1985)
J. Cell Biol.
, vol.100
, pp. 965-973
-
-
Greenspan, P.1
Mayer, E.P.2
Fowler, S.D.3
-
22
-
-
84896823785
-
TRPM2 channels mediate acetaminophen-induced liver damage
-
[22] Kheradpezhouh, E., Ma, L., Morphett, A., Barritt, G.J., Rychkov, G.Y., TRPM2 channels mediate acetaminophen-induced liver damage. Proc. Natl. Acad. Sci. U. S. A. 111 (2014), 3176–3181.
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 3176-3181
-
-
Kheradpezhouh, E.1
Ma, L.2
Morphett, A.3
Barritt, G.J.4
Rychkov, G.Y.5
-
23
-
-
62149132733
-
2 + channel activation in liver cells: evidence from studies using TRPV1 and taurodeoxycholic acid
-
2 + channel activation in liver cells: evidence from studies using TRPV1 and taurodeoxycholic acid. Biochem. J. 418 (2009), 553–566.
-
(2009)
Biochem. J.
, vol.418
, pp. 553-566
-
-
Castro, J.1
Aromataris, E.C.2
Rychkov, G.Y.3
Barritt, G.J.4
-
25
-
-
0024556328
-
Enzyme immunoassays of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate using acetylcholinesterase
-
[25] Pradelles, P., Grassi, J., Chabardes, D., Guiso, N., Enzyme immunoassays of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate using acetylcholinesterase. Anal. Chem. 61 (1989), 447–453.
-
(1989)
Anal. Chem.
, vol.61
, pp. 447-453
-
-
Pradelles, P.1
Grassi, J.2
Chabardes, D.3
Guiso, N.4
-
26
-
-
33644803761
-
Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice
-
[26] Ding, X., Saxena, N.K., Lin, S., Gupta, N.A., Anania, F.A., Exendin-4, a glucagon-like protein-1 (GLP-1) receptor agonist, reverses hepatic steatosis in ob/ob mice. Hepatology 43 (2006), 173–181.
-
(2006)
Hepatology
, vol.43
, pp. 173-181
-
-
Ding, X.1
Saxena, N.K.2
Lin, S.3
Gupta, N.A.4
Anania, F.A.5
-
27
-
-
84862182799
-
Exendin-4 reduces glycemia by increasing liver glucokinase activity: an insulin independent effect
-
[27] Dhanesha, N., Joharapurkar, A., Shah, G., Dhote, V., Kshirsagar, S., Bahekar, R., Jain, M., Exendin-4 reduces glycemia by increasing liver glucokinase activity: an insulin independent effect. Pharmacol. Rep. 64 (2012), 140–149.
-
(2012)
Pharmacol. Rep.
, vol.64
, pp. 140-149
-
-
Dhanesha, N.1
Joharapurkar, A.2
Shah, G.3
Dhote, V.4
Kshirsagar, S.5
Bahekar, R.6
Jain, M.7
-
28
-
-
84870344052
-
Exendin-4 ameliorates diabetic symptoms through activation of glucokinase
-
[28] Dhanesha, N., Joharapurkar, A., Shah, G., Dhote, V., Kshirsagar, S., Bahekar, R., Jain, M., Exendin-4 ameliorates diabetic symptoms through activation of glucokinase. J. Diabetes 4 (2012), 369–377.
-
(2012)
J. Diabetes
, vol.4
, pp. 369-377
-
-
Dhanesha, N.1
Joharapurkar, A.2
Shah, G.3
Dhote, V.4
Kshirsagar, S.5
Bahekar, R.6
Jain, M.7
-
29
-
-
84860325681
-
Glucagon-like peptide-1 receptor agonist, exendin-4, regulates feeding-associated neuropeptides in hypothalamic neurons in vivo and in vitro
-
[29] Dalvi, P.S., Nazarians-Armavil, A., Purser, M.J., Belsham, D.D., Glucagon-like peptide-1 receptor agonist, exendin-4, regulates feeding-associated neuropeptides in hypothalamic neurons in vivo and in vitro. Endocrinology 153 (2012), 2208–2222.
-
(2012)
Endocrinology
, vol.153
, pp. 2208-2222
-
-
Dalvi, P.S.1
Nazarians-Armavil, A.2
Purser, M.J.3
Belsham, D.D.4
-
30
-
-
34047205064
-
Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice
-
[30] Park, C.W., Kim, H.W., Ko, S.H., Lim, J.H., Ryu, G.R., Chung, H.W., Han, S.W., Shin, S.J., Bang, B.K., Breyer, M.D., Chang, Y.S., Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic nephropathy through improving metabolic anomalies in db/db mice. J. Am. Soc. Nephrol. 18 (2007), 1227–1238.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 1227-1238
-
-
Park, C.W.1
Kim, H.W.2
Ko, S.H.3
Lim, J.H.4
Ryu, G.R.5
Chung, H.W.6
Han, S.W.7
Shin, S.J.8
Bang, B.K.9
Breyer, M.D.10
Chang, Y.S.11
-
31
-
-
84861810446
-
Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice
-
[31] Ji, H., Shen, X.D., Zhang, Y., Gao, F., Huang, C.Y., Chang, W.W., Lee, C., Ke, B., Busuttil, R.W., Kupiec-Weglinski, J.W., Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice. Liver Transpl. 18 (2012), 659–670.
-
(2012)
Liver Transpl.
, vol.18
, pp. 659-670
-
-
Ji, H.1
Shen, X.D.2
Zhang, Y.3
Gao, F.4
Huang, C.Y.5
Chang, W.W.6
Lee, C.7
Ke, B.8
Busuttil, R.W.9
Kupiec-Weglinski, J.W.10
-
32
-
-
13244291443
-
Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway
-
[32] Ding, X., Staudinger, J.L., Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway. J. Pharmacol. Exp. Ther. 312 (2005), 849–856.
-
(2005)
J. Pharmacol. Exp. Ther.
, vol.312
, pp. 849-856
-
-
Ding, X.1
Staudinger, J.L.2
-
33
-
-
0021251799
-
Glucagon-stimulable adenylyl cyclase in rat liver. Effects of chronic uremia and intermittent glucagon administration
-
[33] Dighe, R.R., Rojas, F.J., Birnbaumer, L., Garber, A.J., Glucagon-stimulable adenylyl cyclase in rat liver. Effects of chronic uremia and intermittent glucagon administration. J. Clin. Invest. 73 (1984), 1004–1012.
-
(1984)
J. Clin. Invest.
, vol.73
, pp. 1004-1012
-
-
Dighe, R.R.1
Rojas, F.J.2
Birnbaumer, L.3
Garber, A.J.4
-
34
-
-
0022237772
-
Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes
-
[34] Harano, Y., Kashiwagi, A., Kojima, H., Suzuki, M., Hashimoto, T., Shigeta, Y., Phosphorylation of carnitine palmitoyltransferase and activation by glucagon in isolated rat hepatocytes. FEBS Lett. 188 (1985), 267–272.
-
(1985)
FEBS Lett.
, vol.188
, pp. 267-272
-
-
Harano, Y.1
Kashiwagi, A.2
Kojima, H.3
Suzuki, M.4
Hashimoto, T.5
Shigeta, Y.6
-
35
-
-
84860510820
-
Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes
-
[35] Wang, Y., Li, G., Goode, J., Paz, J.C., Ouyang, K., Screaton, R., Fischer, W.H., Chen, J., Tabas, I., Montminy, M., Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes. Nature 485 (2012), 128–132.
-
(2012)
Nature
, vol.485
, pp. 128-132
-
-
Wang, Y.1
Li, G.2
Goode, J.3
Paz, J.C.4
Ouyang, K.5
Screaton, R.6
Fischer, W.H.7
Chen, J.8
Tabas, I.9
Montminy, M.10
-
36
-
-
0023099179
-
Mechanisms of hormonal regulation of hepatic glucose metabolism
-
[36] Exton, J.H., Mechanisms of hormonal regulation of hepatic glucose metabolism. Diabetes Metab. Rev. 3 (1987), 163–183.
-
(1987)
Diabetes Metab. Rev.
, vol.3
, pp. 163-183
-
-
Exton, J.H.1
-
37
-
-
0019362941
-
Mechanisms of hormonal regulation of liver metabolism
-
[37] Exton, J.H., Blackmore, P.F., El-Refai, M.F., Dehaye, J.P., Strickland, W.G., Cherrington, A.D., Chan, T.M., Assimacopoulos-Jeannet, F.D., Chrisman, T.D., Mechanisms of hormonal regulation of liver metabolism. Adv. Cyclic Nucleotide Res. 14 (1981), 491–505.
-
(1981)
Adv. Cyclic Nucleotide Res.
, vol.14
, pp. 491-505
-
-
Exton, J.H.1
Blackmore, P.F.2
El-Refai, M.F.3
Dehaye, J.P.4
Strickland, W.G.5
Cherrington, A.D.6
Chan, T.M.7
Assimacopoulos-Jeannet, F.D.8
Chrisman, T.D.9
-
38
-
-
0023402206
-
Regulation of phosphoenolpyruvate carboxykinase gene transcription in H4IIE hepatoma cells: evidence for a primary role of the catalytic subunit of 3',5'-cyclic adenosine monophosphate-dependent protein kinase
-
[38] Beebe, S.J., Koch, S.R., Chu, D.T., Corbin, J.D., Granner, D.K., Regulation of phosphoenolpyruvate carboxykinase gene transcription in H4IIE hepatoma cells: evidence for a primary role of the catalytic subunit of 3',5'-cyclic adenosine monophosphate-dependent protein kinase. Mol. Endocrinol. 1 (1987), 639–647.
-
(1987)
Mol. Endocrinol.
, vol.1
, pp. 639-647
-
-
Beebe, S.J.1
Koch, S.R.2
Chu, D.T.3
Corbin, J.D.4
Granner, D.K.5
-
39
-
-
0020486799
-
Lipolysis of hepatic triacylglycerol stores
-
[39] Debeer, L.J., Beynen, A.C., Mannaerts, G.P., Geelen, M.J., Lipolysis of hepatic triacylglycerol stores. FEBS Lett. 140 (1982), 159–164.
-
(1982)
FEBS Lett.
, vol.140
, pp. 159-164
-
-
Debeer, L.J.1
Beynen, A.C.2
Mannaerts, G.P.3
Geelen, M.J.4
-
40
-
-
84868120544
-
The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis
-
[40] Gupta, N.A., Kolachala, V.L., Jiang, R., Abramowsky, C., Romero, R., Fifadara, N., Anania, F., Knechtle, S., Kirk, A., The glucagon-like peptide-1 receptor agonist Exendin 4 has a protective role in ischemic injury of lean and steatotic liver by inhibiting cell death and stimulating lipolysis. Am. J. Pathol. 181 (2012), 1693–1701.
-
(2012)
Am. J. Pathol.
, vol.181
, pp. 1693-1701
-
-
Gupta, N.A.1
Kolachala, V.L.2
Jiang, R.3
Abramowsky, C.4
Romero, R.5
Fifadara, N.6
Anania, F.7
Knechtle, S.8
Kirk, A.9
-
41
-
-
77951436599
-
Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway
-
[41] Gupta, N.A., Mells, J., Dunham, R.M., Grakoui, A., Handy, J., Saxena, N.K., Anania, F.A., Glucagon-like peptide-1 receptor is present on human hepatocytes and has a direct role in decreasing hepatic steatosis in vitro by modulating elements of the insulin signaling pathway. Hepatology 51 (2010), 1584–1592.
-
(2010)
Hepatology
, vol.51
, pp. 1584-1592
-
-
Gupta, N.A.1
Mells, J.2
Dunham, R.M.3
Grakoui, A.4
Handy, J.5
Saxena, N.K.6
Anania, F.A.7
-
42
-
-
80053001967
-
GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy
-
[42] Sharma, S., Mells, J.E., Fu, P.P., Saxena, N.K., Anania, F.A., GLP-1 analogs reduce hepatocyte steatosis and improve survival by enhancing the unfolded protein response and promoting macroautophagy. PLoS One, 6, 2011, e25269.
-
(2011)
PLoS One
, vol.6
, pp. e25269
-
-
Sharma, S.1
Mells, J.E.2
Fu, P.P.3
Saxena, N.K.4
Anania, F.A.5
-
43
-
-
0037407834
-
2 + influx and IL-2 production in T lymphocytes
-
2 + influx and IL-2 production in T lymphocytes. J. Immunol. 170 (2003), 4441–4449.
-
(2003)
J. Immunol.
, vol.170
, pp. 4441-4449
-
-
Ishikawa, J.1
Ohga, K.2
Yoshino, T.3
Takezawa, R.4
Ichikawa, A.5
Kubota, H.6
Yamada, T.7
-
44
-
-
84879442910
-
Calcium signaling in the liver
-
[44] Amaya, M.J., Nathanson, M.H., Calcium signaling in the liver. Compr. Physiol. 3 (2013), 515–539.
-
(2013)
Compr. Physiol.
, vol.3
, pp. 515-539
-
-
Amaya, M.J.1
Nathanson, M.H.2
-
45
-
-
0026520193
-
Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis
-
[45] Pilkis, S.J., Granner, D.K., Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Annu. Rev. Physiol. 54 (1992), 885–909.
-
(1992)
Annu. Rev. Physiol.
, vol.54
, pp. 885-909
-
-
Pilkis, S.J.1
Granner, D.K.2
-
46
-
-
0020561535
-
Effect of glucagon, phenylephrine, and isoproterenol on glycogenolysis and glucose release from fetal rat hepatocytes in suspension
-
[46] Huhn, W., Schulze, H.P., Dargel, R., Effect of glucagon, phenylephrine, and isoproterenol on glycogenolysis and glucose release from fetal rat hepatocytes in suspension. Biol. Neonate 44 (1983), 153–157.
-
(1983)
Biol. Neonate
, vol.44
, pp. 153-157
-
-
Huhn, W.1
Schulze, H.P.2
Dargel, R.3
-
47
-
-
84860497397
-
Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance
-
[47] Jornayvaz, F.R., Shulman, G.I., Diacylglycerol activation of protein kinase Cepsilon and hepatic insulin resistance. Cell Metab. 15 (2012), 574–584.
-
(2012)
Cell Metab.
, vol.15
, pp. 574-584
-
-
Jornayvaz, F.R.1
Shulman, G.I.2
-
48
-
-
36849040001
-
Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice
-
[48] Flock, G., Baggio, L.L., Longuet, C., Drucker, D.J., Incretin receptors for glucagon-like peptide 1 and glucose-dependent insulinotropic polypeptide are essential for the sustained metabolic actions of vildagliptin in mice. Diabetes 56 (2007), 3006–3013.
-
(2007)
Diabetes
, vol.56
, pp. 3006-3013
-
-
Flock, G.1
Baggio, L.L.2
Longuet, C.3
Drucker, D.J.4
-
49
-
-
80052517174
-
Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis
-
[49] Svegliati-Baroni, G., Saccomanno, S., Rychlicki, C., Agostinelli, L., De Minicis, S., Candelaresi, C., Faraci, G., Pacetti, D., Vivarelli, M., Nicolini, D., Garelli, P., Casini, A., Manco, M., Mingrone, G., Risaliti, A., Frega, G.N., Benedetti, A., Gastaldelli, A., Glucagon-like peptide-1 receptor activation stimulates hepatic lipid oxidation and restores hepatic signalling alteration induced by a high-fat diet in nonalcoholic steatohepatitis. Liver Int. 31 (2011), 1285–1297.
-
(2011)
Liver Int.
, vol.31
, pp. 1285-1297
-
-
Svegliati-Baroni, G.1
Saccomanno, S.2
Rychlicki, C.3
Agostinelli, L.4
De Minicis, S.5
Candelaresi, C.6
Faraci, G.7
Pacetti, D.8
Vivarelli, M.9
Nicolini, D.10
Garelli, P.11
Casini, A.12
Manco, M.13
Mingrone, G.14
Risaliti, A.15
Frega, G.N.16
Benedetti, A.17
Gastaldelli, A.18
-
50
-
-
84860497397
-
Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance
-
[50] Jornayvaz, F.R., Shulman, G.I., Diacylglycerol activation of protein kinase Cε and hepatic insulin resistance. Cell Metab. 15 (2012), 574–584.
-
(2012)
Cell Metab.
, vol.15
, pp. 574-584
-
-
Jornayvaz, F.R.1
Shulman, G.I.2
-
51
-
-
79953173175
-
GLP-1-derived nonapeptide GLP-1(28-36)amide targets to mitochondria and suppresses glucose production and oxidative stress in isolated mouse hepatocytes
-
[51] Tomas, E., Stanojevic, V., Habener, J.F., GLP-1-derived nonapeptide GLP-1(28-36)amide targets to mitochondria and suppresses glucose production and oxidative stress in isolated mouse hepatocytes. Regul. Pept. 167 (2011), 177–184.
-
(2011)
Regul. Pept.
, vol.167
, pp. 177-184
-
-
Tomas, E.1
Stanojevic, V.2
Habener, J.F.3
-
52
-
-
84937545993
-
Autophagy and lipid droplets in the liver
-
[52] Martinez-Lopez, N., Singh, R., Autophagy and lipid droplets in the liver. Annu. Rev. Nutr. 35 (2015), 215–237.
-
(2015)
Annu. Rev. Nutr.
, vol.35
, pp. 215-237
-
-
Martinez-Lopez, N.1
Singh, R.2
-
53
-
-
84939653868
-
Hepatic lipid droplet biology: getting to the root of fatty liver
-
[53] Mashek, D.G., Khan, S.A., Sathyanarayan, A., Ploeger, J.M., Franklin, M.P., Hepatic lipid droplet biology: getting to the root of fatty liver. Hepatology 62 (2015), 964–967.
-
(2015)
Hepatology
, vol.62
, pp. 964-967
-
-
Mashek, D.G.1
Khan, S.A.2
Sathyanarayan, A.3
Ploeger, J.M.4
Franklin, M.P.5
-
55
-
-
84931402437
-
Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH
-
[55] Amrutkar, M., Cansby, E., Nunez-Duran, E., Pirazzi, C., Stahlman, M., Stenfeldt, E., Smith, U., Boren, J., Mahlapuu, M., Protein kinase STK25 regulates hepatic lipid partitioning and progression of liver steatosis and NASH. FASEB J. 29 (2015), 1564–1576.
-
(2015)
FASEB J.
, vol.29
, pp. 1564-1576
-
-
Amrutkar, M.1
Cansby, E.2
Nunez-Duran, E.3
Pirazzi, C.4
Stahlman, M.5
Stenfeldt, E.6
Smith, U.7
Boren, J.8
Mahlapuu, M.9
-
56
-
-
84894104800
-
Perilipin discerns chronic from acute hepatocellular steatosis
-
[56] Pawella, L.M., Hashani, M., Eiteneuer, E., Renner, M., Bartenschlager, R., Schirmacher, P., Straub, B.K., Perilipin discerns chronic from acute hepatocellular steatosis. J. Hepatol. 60 (2014), 633–642.
-
(2014)
J. Hepatol.
, vol.60
, pp. 633-642
-
-
Pawella, L.M.1
Hashani, M.2
Eiteneuer, E.3
Renner, M.4
Bartenschlager, R.5
Schirmacher, P.6
Straub, B.K.7
-
57
-
-
84861913952
-
Lipid droplets and cellular lipid metabolism
-
[57] Walther, T.C., Farese, R.V. Jr., Lipid droplets and cellular lipid metabolism. Annu. Rev. Biochem. 81 (2012), 687–714.
-
(2012)
Annu. Rev. Biochem.
, vol.81
, pp. 687-714
-
-
Walther, T.C.1
Farese, R.V.2
-
59
-
-
78650615554
-
2 +-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity
-
2 +-ATPase 2b is a major regulator of endoplasmic reticulum stress and glucose homeostasis in obesity. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 19320–19325.
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 19320-19325
-
-
Park, S.W.1
Zhou, Y.2
Lee, J.3
Lee, J.4
Ozcan, U.5
-
60
-
-
84919596822
-
Structural and functional mechanisms of CRAC channel regulation
-
[60] Shim, A.H., Tirado-Lee, L., Prakriya, M., Structural and functional mechanisms of CRAC channel regulation. J. Mol. Biol. 427 (2015), 77–93.
-
(2015)
J. Mol. Biol.
, vol.427
, pp. 77-93
-
-
Shim, A.H.1
Tirado-Lee, L.2
Prakriya, M.3
-
61
-
-
84919696212
-
GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance
-
[61] Taher, J., Baker, C.L., Cuizon, C., Masoudpour, H., Zhang, R., Farr, S., Naples, M., Bourdon, C., Pausova, Z., Adeli, K., GLP-1 receptor agonism ameliorates hepatic VLDL overproduction and de novo lipogenesis in insulin resistance. Mol. Metab. 3 (2014), 823–833.
-
(2014)
Mol. Metab.
, vol.3
, pp. 823-833
-
-
Taher, J.1
Baker, C.L.2
Cuizon, C.3
Masoudpour, H.4
Zhang, R.5
Farr, S.6
Naples, M.7
Bourdon, C.8
Pausova, Z.9
Adeli, K.10
-
62
-
-
79956114434
-
Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase
-
[62] Ben-Shlomo, S., Zvibel, I., Shnell, M., Shlomai, A., Chepurko, E., Halpern, Z., Barzilai, N., Oren, R., Fishman, S., Glucagon-like peptide-1 reduces hepatic lipogenesis via activation of AMP-activated protein kinase. J. Hepatol. 54 (2011), 1214–1223.
-
(2011)
J. Hepatol.
, vol.54
, pp. 1214-1223
-
-
Ben-Shlomo, S.1
Zvibel, I.2
Shnell, M.3
Shlomai, A.4
Chepurko, E.5
Halpern, Z.6
Barzilai, N.7
Oren, R.8
Fishman, S.9
-
63
-
-
84893508942
-
A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity
-
[63] Baumbach, J., Hummel, P., Bickmeyer, I., Kowalczyk, K.M., Frank, M., Knorr, K., Hildebrandt, A., Riedel, D., Jackle, H., Kuhnlein, R.P., A Drosophila in vivo screen identifies store-operated calcium entry as a key regulator of adiposity. Cell Metab. 19 (2014), 331–343.
-
(2014)
Cell Metab.
, vol.19
, pp. 331-343
-
-
Baumbach, J.1
Hummel, P.2
Bickmeyer, I.3
Kowalczyk, K.M.4
Frank, M.5
Knorr, K.6
Hildebrandt, A.7
Riedel, D.8
Jackle, H.9
Kuhnlein, R.P.10
-
64
-
-
84856072854
-
Packaging of fat: an evolving model of lipid droplet assembly and expansion
-
[64] Brasaemle, D.L., Wolins, N.E., Packaging of fat: an evolving model of lipid droplet assembly and expansion. J. Biol. Chem. 287 (2012), 2273–2279.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 2273-2279
-
-
Brasaemle, D.L.1
Wolins, N.E.2
-
65
-
-
80054776671
-
Endoplasmic-reticulum calcium depletion and disease
-
[65] Mekahli, D., Bultynck, G., Parys, J.B., De Smedt, H., Missiaen, L., Endoplasmic-reticulum calcium depletion and disease. Cold Spring Harb. Perspect. Biol., 3, 2011.
-
(2011)
Cold Spring Harb. Perspect. Biol.
, vol.3
-
-
Mekahli, D.1
Bultynck, G.2
Parys, J.B.3
De Smedt, H.4
Missiaen, L.5
-
66
-
-
84904399681
-
Exendin-4 regulates lipid metabolism and fibroblast growth factor 21 in hepatic steatosis
-
[66] Lee, J., Hong, S.W., Park, S.E., Rhee, E.J., Park, C.Y., Oh, K.W., Park, S.W., Lee, W.Y., Exendin-4 regulates lipid metabolism and fibroblast growth factor 21 in hepatic steatosis. Metabolism 63 (2014), 1041–1048.
-
(2014)
Metabolism
, vol.63
, pp. 1041-1048
-
-
Lee, J.1
Hong, S.W.2
Park, S.E.3
Rhee, E.J.4
Park, C.Y.5
Oh, K.W.6
Park, S.W.7
Lee, W.Y.8
-
67
-
-
84946557995
-
Control of liver glucokinase activity: a potential new target for incretin hormones?
-
[67] Francini, F., Massa, M.L., Polo, M.P., Villagarcia, H., Castro, M.C., Gagliardino, J.J., Control of liver glucokinase activity: a potential new target for incretin hormones?. Peptides 74 (2015), 57–63.
-
(2015)
Peptides
, vol.74
, pp. 57-63
-
-
Francini, F.1
Massa, M.L.2
Polo, M.P.3
Villagarcia, H.4
Castro, M.C.5
Gagliardino, J.J.6
-
68
-
-
84907189265
-
Exendin-4 improves nonalcoholic fatty liver disease by regulating glucose transporter 4 expression in ob/ob mice
-
[68] Kim, S., Jung, J., Kim, H., Heo, R.W., Yi, C.O., Lee, J.E., Jeon, B.T., Kim, W.H., Hahm, J.R., Roh, G.S., Exendin-4 improves nonalcoholic fatty liver disease by regulating glucose transporter 4 expression in ob/ob mice. Korean J. Physiol. Pharmacol. 18 (2014), 333–339.
-
(2014)
Korean J. Physiol. Pharmacol.
, vol.18
, pp. 333-339
-
-
Kim, S.1
Jung, J.2
Kim, H.3
Heo, R.W.4
Yi, C.O.5
Lee, J.E.6
Jeon, B.T.7
Kim, W.H.8
Hahm, J.R.9
Roh, G.S.10
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