Co-expression of truncated and full-length tau induces severe neurotoxicity

Molecular Psychiatry

Volumn 21, Issue 12, 2016, Pages 1790-1798

  Ozcelik, S ^a,b   Sprenger, F ^a,b   Skachokova, Z ^a,b   Fraser, G ^c   Abramowski, D ^d   Clavaguera, F ^a   Probst, A ^a   Frank, S ^a   Muller M ^d   Staufenbiel, M ^d   Goedert, M ^c   Tolnay, M ^a   Winkler, D T ^a,b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY HOSPITAL BASEL   (Switzerland)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; TAU PROTEIN; TETRACYCLINE; ISOPROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATAXIC GAIT; BRAIN HISTOLOGY; BRAIN STEM; CONTROLLED STUDY; DNA FRAGMENTATION; GOLGI COMPLEX; HEREDITARY MOTOR SENSORY NEUROPATHY; HINDLIMB; HIPPOCAMPUS; LOCOMOTION; MITOCHONDRION; MOLECULAR WEIGHT; MOTONEURON; MOUSE; MYOPATHY; NERVE CELL LESION; NERVE FIBER TRANSPORT; NEUROTOXICITY; NONHUMAN; PARALYSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCIATIC NERVE; SPINAL CORD; SYNAPSE; TAUOPATHY; TREMOR; WALLERIAN DEGENERATION; ALZHEIMER DISEASE; ANIMAL; BRAIN; DISEASE MODEL; HUMAN; METABOLISM; NERVE CELL; PHYSIOLOGY; PROTEIN STRUCTURE; TOXICITY AND INTOXICATION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; ANIMALS; AXONAL TRANSPORT; BRAIN; DISEASE MODELS, ANIMAL; HUMANS; MICE; MICE, TRANSGENIC; NEURONS; NEUROTOXICITY SYNDROMES; PROTEIN ISOFORMS; PROTEIN STRUCTURAL ELEMENTS; TAU PROTEINS; TAUOPATHIES;

EID: 84989928964     PISSN: 13594184     EISSN: 14765578     Source Type: Journal    
DOI: 10.1038/mp.2015.228     Document Type: Article

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