메뉴 건너뛰기




Volumn 54, Issue 5, 2016, Pages 601-608

Mechanisms of asthma in obesity pleiotropic aspects of obesity produce distinct asthma phenotypes

Author keywords

Asthma; Diet; Obesity; Phenotype

Indexed keywords

CRYOPYRIN; INTERLEUKIN 1BETA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; IRRITANT AGENT;

EID: 84988922673     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2016-0017PS     Document Type: Review
Times cited : (122)

References (82)
  • 1
    • 39449101231 scopus 로고    scopus 로고
    • BMI and health status among adults with asthma
    • Vortmann M, Eisner MD. BMI and health status among adults with asthma. Obesity (Silver Spring) 2008;16:146-152
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 146-152
    • Vortmann, M.1    Eisner, M.D.2
  • 2
    • 50949108389 scopus 로고    scopus 로고
    • The relationship between obesity and asthma severity and control in adults
    • Mosen DM, Schatz M, Magid DJ, Camargo CA Jr. The relationship between obesity and asthma severity and control in adults. J Allergy Clin Immunol 2008;122:507-11.e6
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 507e6-511e6
    • Mosen, D.M.1    Schatz, M.2    Magid, D.J.3    Camargo, C.A.4
  • 5
    • 34748878277 scopus 로고    scopus 로고
    • Influence of obesity on response to fluticasone with or without salmeterol in moderate asthma
    • Boulet LP, Franssen E. Influence of obesity on response to fluticasone with or without salmeterol in moderate asthma. Respir Med 2007;101: 2240-2247
    • (2007) Respir Med , vol.101 , pp. 2240-2247
    • Boulet, L.P.1    Franssen, E.2
  • 10
  • 14
    • 0028817013 scopus 로고
    • Airway hyperresponsiveness in asthma: A problem of limited smooth muscle relaxation with inspiration
    • Skloot G, Permutt S, Togias A. Airway hyperresponsiveness in asthma: a problem of limited smooth muscle relaxation with inspiration. J Clin Invest 1995;96:2393-2403
    • (1995) J Clin Invest , vol.96 , pp. 2393-2403
    • Skloot, G.1    Permutt, S.2    Togias, A.3
  • 15
    • 84920433579 scopus 로고    scopus 로고
    • Potential role of the airway wall in the asthma of obesity
    • Bates JH, Dixon AE. Potential role of the airway wall in the asthma of obesity. J Appl Physiol (1985) 2015;118:36-41
    • (2015) J Appl Physiol (1985) , vol.118 , pp. 36-41
    • Bates, J.H.1    Dixon, A.E.2
  • 17
    • 80054878979 scopus 로고    scopus 로고
    • Nitric oxide metabolism in asthma pathophysiology
    • Ghosh S, Erzurum SC. Nitric oxide metabolism in asthma pathophysiology. Biochim Biophys Acta 2011;1810:1008-1016
    • (2011) Biochim Biophys Acta , vol.1810 , pp. 1008-1016
    • Ghosh, S.1    Erzurum, S.C.2
  • 19
    • 49649113435 scopus 로고    scopus 로고
    • Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation
    • Johnston RA, Theman TA, Lu FL, Terry RD, Williams ES, Shore SA. Diet-induced obesity causes innate airway hyperresponsiveness to methacholine and enhances ozone-induced pulmonary inflammation. J Appl Physiol (1985) 2008;104:1727-1735
    • (2008) J Appl Physiol (1985) , vol.104 , pp. 1727-1735
    • Johnston, R.A.1    Theman, T.A.2    Lu, F.L.3    Terry, R.D.4    Williams, E.S.5    Shore, S.A.6
  • 23
    • 84926679318 scopus 로고    scopus 로고
    • Induction of IL-17A precedes development of airway hyperresponsiveness during diet-induced obesity and correlates with complement factor D
    • Mathews JA, Wurmbrand AP, Ribeiro L, Neto FL, Shore SA. Induction of IL-17A precedes development of airway hyperresponsiveness during diet-induced obesity and correlates with complement factor D. Front Immunol 2014;5:440
    • (2014) Front Immunol , vol.5 , pp. 440
    • Mathews, J.A.1    Wurmbrand, A.P.2    Ribeiro, L.3    Neto, F.L.4    Shore, S.A.5
  • 25
    • 84905512893 scopus 로고    scopus 로고
    • Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats
    • Nie Z, Jacoby DB, Fryer AD. Hyperinsulinemia potentiates airway responsiveness to parasympathetic nerve stimulation in obese rats. Am J Respir Cell Mol Biol 2014;51:251-261
    • (2014) Am J Respir Cell Mol Biol , vol.51 , pp. 251-261
    • Nie, Z.1    Jacoby, D.B.2    Fryer, A.D.3
  • 27
    • 84872124577 scopus 로고    scopus 로고
    • Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma
    • Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metab 2013;17:35-48
    • (2013) Cell Metab , vol.17 , pp. 35-48
    • Arteaga-Solis, E.1    Zee, T.2    Emala, C.W.3    Vinson, C.4    Wess, J.5    Karsenty, G.6
  • 28
    • 55449096455 scopus 로고    scopus 로고
    • No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice
    • Shore SA, Williams ES, Zhu M. No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol (1985) 2008;105:1127-1133
    • (2008) J Appl Physiol (1985) , vol.105 , pp. 1127-1133
    • Shore, S.A.1    Williams, E.S.2    Zhu, M.3
  • 29
    • 84960340702 scopus 로고    scopus 로고
    • A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity
    • Dixon AE, Subramanian M, DeSarno M, Black K, Lane L, Holguin F. A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity. Respir Res 2015;16:143
    • (2015) Respir Res , vol.16 , pp. 143
    • Dixon, A.E.1    Subramanian, M.2    DeSarno, M.3    Black, K.4    Lane, L.5    Holguin, F.6
  • 31
    • 84982267585 scopus 로고    scopus 로고
    • Maternal high-fat hypercaloric diet during pregnancy results in persistent metabolic and respiratory abnormalities in offspring
    • [online ahead of print] 23 Dec
    • Griffiths PS, Walton C, Samsell L, Perez MK, Piedimonte G. Maternal high-fat hypercaloric diet during pregnancy results in persistent metabolic and respiratory abnormalities in offspring. Pediatr Res [online ahead of print] 23 Dec 2015; DOI: 10.1038/pr.2015.226
    • (2015) Pediatr Res
    • Griffiths, P.S.1    Walton, C.2    Samsell, L.3    Perez, M.K.4    Piedimonte, G.5
  • 33
    • 84922317284 scopus 로고    scopus 로고
    • Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome
    • Leishangthem GD, Mabalirajan U, Singh VP, Agrawal A, Ghosh B, Dinda AK. Ultrastructural changes of airway in murine models of allergy and diet-induced metabolic syndrome. ISRN Allergy 2013; 2013:261297
    • (2013) ISRN Allergy , vol.2013 , pp. 261297
    • Leishangthem, G.D.1    Mabalirajan, U.2    Singh, V.P.3    Agrawal, A.4    Ghosh, B.5    Dinda, A.K.6
  • 36
    • 41749115987 scopus 로고    scopus 로고
    • Airway inflammation in obese and nonobese patients with difficult-to-treat asthma
    • van Veen IH, Ten Brinke A, Sterk PJ, Rabe KF, Bel EH. Airway inflammation in obese and nonobese patients with difficult-to-treat asthma. Allergy 2008;63:570-574
    • (2008) Allergy , vol.63 , pp. 570-574
    • Van Veen, I.H.1    Ten Brinke, A.2    Sterk, P.J.3    Rabe, K.F.4    Bel, E.H.5
  • 39
    • 84901022856 scopus 로고    scopus 로고
    • Eosinophilic inflammation in subjects with mild-tomoderate asthma with and without obesity: Disparity between sputum and biopsies
    • van der Wiel E, Ten Hacken NH, van den Berge M, Timens W, Reddel HK, Postma DS. Eosinophilic inflammation in subjects with mild-tomoderate asthma with and without obesity: disparity between sputum and biopsies. Am J Respir Crit Care Med 2014;189: 1281-1284
    • (2014) Am J Respir Crit Care Med , vol.189 , pp. 1281-1284
    • Vander Wiel, E.1    Ten Hacken, N.H.2    Vanden Berge, M.3    Timens, W.4    Reddel, H.K.5    Postma, D.S.6
  • 41
    • 84946595069 scopus 로고    scopus 로고
    • Obesity enhances Th2 inflammatory response via natural killer T cells in a murine model of allergic asthma
    • Chen YP, Zhang JH, Li CQ, Sun QX, Jiang XH. Obesity enhances Th2 inflammatory response via natural killer T cells in a murine model of allergic asthma. Int J Clin Exp Med 2015;8:15403-15412
    • (2015) J Clin Exp Med , vol.8 , pp. 15403-15412
    • Chen, Y.P.1    Zhang, J.H.2    Li, C.Q.3    Sun, Q.X.4    Jiang, X.H.5
  • 43
    • 84866743988 scopus 로고    scopus 로고
    • Allergen-induced bone marrow eosinophilopoiesis and airways eosinophilic inflammation in leptin-deficient ob/ob mice
    • Lintomen L, Calixto MC, Schenka A, Antunes E. Allergen-induced bone marrow eosinophilopoiesis and airways eosinophilic inflammation in leptin-deficient ob/ob mice. Obesity (Silver Spring) 2012;20: 1959-1965
    • (2012) Obesity (Silver Spring) , vol.20 , pp. 1959-1965
    • Lintomen, L.1    Calixto, M.C.2    Schenka, A.3    Antunes, E.4
  • 44
    • 84922552062 scopus 로고    scopus 로고
    • Obesity increases airway hyperresponsiveness via the TNF-A pathway and treating obesity induces recovery
    • Kim JY, Sohn JH, Lee JH, Park JW. Obesity increases airway hyperresponsiveness via the TNF-A pathway and treating obesity induces recovery. PLoS One 2015;10:e0116540
    • (2015) PLoS One , vol.10 , pp. e0116540
    • Kim, J.Y.1    Sohn, J.H.2    Lee, J.H.3    Park, J.W.4
  • 45
    • 33746516349 scopus 로고    scopus 로고
    • Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
    • Shore SA, Terry RD, Flynt L, Xu A, Hug C. Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol 2006;118:389-395
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 389-395
    • Shore, S.A.1    Terry, R.D.2    Flynt, L.3    Xu, A.4    Hug, C.5
  • 50
    • 84952902890 scopus 로고    scopus 로고
    • Immunometabolism: Cellular metabolism turns immune regulator
    • Loftus RM, Finlay DK. Immunometabolism: cellular metabolism turns immune regulator. J Biol Chem 2016;291:1-10
    • (2016) J Biol Chem , vol.291 , pp. 1-10
    • Loftus, R.M.1    Finlay, D.K.2
  • 55
    • 84925581335 scopus 로고    scopus 로고
    • Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity
    • Arruda AP, Pers BM, Parlakgül G, Güney E, Inouye K, Hotamisligil GS. Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity. Nat Med 2014; 20:1427-1435
    • (2014) Nat Med , vol.20 , pp. 1427-1435
    • Arruda, A.P.1    Pers, B.M.2    Parlakgül, G.3    Güney, E.4    Inouye, K.5    Hotamisligil, G.S.6
  • 59
    • 79955601400 scopus 로고    scopus 로고
    • A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma
    • Wood LG, Garg ML, Gibson PG. A high-fat challenge increases airway inflammation and impairs bronchodilator recovery in asthma. J Allergy Clin Immunol 2011;127:1133-1140
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1133-1140
    • Wood, L.G.1    Garg, M.L.2    Gibson, P.G.3
  • 60
    • 84983097666 scopus 로고    scopus 로고
    • Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes
    • Kien CL, Bunn JY, Fukagawa NK, Anathy V, Matthews DE, Crain KI, Ebenstein DB, Tarleton EK, Pratley RE, Poynter ME. Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes. J Nutr Biochem 2015;26:1599-1606
    • (2015) J Nutr Biochem , vol.26 , pp. 1599-1606
    • Kien, C.L.1    Bunn, J.Y.2    Fukagawa, N.K.3    Anathy, V.4    Matthews, D.E.5    Crain, K.I.6    Ebenstein, D.B.7    Tarleton, E.K.8    Pratley, R.E.9    Poynter, M.E.10
  • 61
    • 84922764956 scopus 로고    scopus 로고
    • Dietary pattern and asthma: A systematic review and meta-analysis
    • Lv N, Xiao L, Ma J. Dietary pattern and asthma: a systematic review and meta-analysis. J Asthma Allergy 2014;7:105-121
    • (2014) J Asthma Allergy , vol.7 , pp. 105-121
    • Lv, N.1    Xiao, L.2    Ma, J.3
  • 67
  • 68
    • 84930883678 scopus 로고    scopus 로고
    • Airway epithelial NF-kB activation promotes the ability to overcome inhalational antigen tolerance
    • Ather JL, Foley KL, Suratt BT, Boyson JE, Poynter ME. Airway epithelial NF-kB activation promotes the ability to overcome inhalational antigen tolerance. Clin Exp Allergy 2015;45:1245-1258
    • (2015) Clin Exp Allergy , vol.45 , pp. 1245-1258
    • Ather, J.L.1    Foley, K.L.2    Suratt, B.T.3    Boyson, J.E.4    Poynter, M.E.5
  • 69
    • 80054943310 scopus 로고    scopus 로고
    • Epithelial, dendritic, and CD4(1) T cell regulation of and by reactive oxygen and nitrogen species in allergic sensitization
    • Ckless K, Hodgkins SR, Ather JL, Martin R, Poynter ME. Epithelial, dendritic, and CD4(1) T cell regulation of and by reactive oxygen and nitrogen species in allergic sensitization. Biochim Biophys Acta 2011;1810:1025-1034
    • (2011) Biochim Biophys Acta , vol.1810 , pp. 1025-1034
    • Ckless, K.1    Hodgkins, S.R.2    Ather, J.L.3    Martin, R.4    Poynter, M.E.5
  • 70
    • 0034880752 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and adipose tissue
    • Coppack SW. Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 2001;60:349-356
    • (2001) Proc Nutr Soc , vol.60 , pp. 349-356
    • Coppack, S.W.1
  • 71
    • 37549023822 scopus 로고    scopus 로고
    • Ozone exposure and lung function: Effect modified by obesity and airways hyperresponsiveness in the VA normative aging study
    • Alexeeff SE, Litonjua AA, Suh H, Sparrow D, Vokonas PS, Schwartz J. Ozone exposure and lung function: effect modified by obesity and airways hyperresponsiveness in the VA normative aging study. Chest 2007;132:1890-1897
    • (2007) Chest , vol.132 , pp. 1890-1897
    • Alexeeff, S.E.1    Litonjua, A.A.2    Suh, H.3    Sparrow, D.4    Vokonas, P.S.5    Schwartz, J.6
  • 72
    • 84872116552 scopus 로고    scopus 로고
    • Obesity enhanced respiratory health effects of ambient air pollution in Chinese children: The Seven Northeastern Cities study
    • Dong GH, Qian Z, Liu MM, Wang D, Ren WH, Fu Q, Wang J, Simckes M, Ferguson TF, Trevathan E. Obesity enhanced respiratory health effects of ambient air pollution in Chinese children: the Seven Northeastern Cities study. Int J Obes 2013;37:94-100
    • (2013) J Obes , vol.37 , pp. 94-100
    • Dong, G.H.1    Qian, Z.2    Liu, M.M.3    Wang, D.4    Ren, W.H.5    Fu, Q.6    Wang, J.7    Simckes, M.8    Ferguson, T.F.9    Trevathan, E.10
  • 81
    • 84869501433 scopus 로고    scopus 로고
    • Obesity lowers the threshold of allergic sensitization and augments airway eosinophilia in a mouse model of asthma
    • Dietze J, Bocking C, Heverhagen JT, Voelker MN, Renz H. Obesity lowers the threshold of allergic sensitization and augments airway eosinophilia in a mouse model of asthma. Allergy 2012;67: 1519-1529
    • (2012) Allergy , vol.67 , pp. 1519-1529
    • Dietze, J.1    Bocking, C.2    Heverhagen, J.T.3    Voelker, M.N.4    Renz, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.