Influence of distinct asthma phenotypes on lung function following weight loss in the obese

Respirology

Volumn 19, Issue 8, 2014, Pages 1170-1177

  Chapman, David G ^a   Irvin, Charles G ^a   Kaminsky, David A ^a   Forgione, Patrick M ^a   Bates, Jason H T ^a   Dixon, Anne E ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

Author keywords

Airway closure; Airway hyperresponsiveness; Asthma; Obesity; Weight loss

Indexed keywords

IMMUNOGLOBULIN E; METHACHOLINE;

ADULT; AIRWAY OBSTRUCTION; ARTICLE; ASTHMA; BARIATRIC SURGERY; DOSE RESPONSE; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; HUMAN; LUNG FUNCTION; LUNG RESISTANCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OBESITY; OSCILLATION; PHENOTYPE; SPIROMETRY; WEIGHT REDUCTION; BLOOD; IMMUNOLOGY; INHALATION TEST; ONSET AGE; PATHOPHYSIOLOGY; PROCEDURES; RESPIRATORY SYSTEM; RESPIRATORY TRACT ALLERGY;

ADULT; AGE OF ONSET; ASTHMA; BARIATRIC SURGERY; BRONCHIAL PROVOCATION TESTS; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; IMMUNOGLOBULIN E; MALE; MIDDLE AGED; OBESITY; PHENOTYPE; RESPIRATORY HYPERSENSITIVITY; RESPIRATORY SYSTEM; WEIGHT LOSS;

EID: 84908020996     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/resp.12368     Document Type: Article

References (33)

1. Cazzoletti L, Marcon A, Janson C, Corsico A, Jarvis D, Pin I, Accordini S, Almar E, Bugiani M, Carolei A et al. Asthma control in Europe: a real-world evaluation based on an international population-based study. J. Allergy Clin. Immunol. 2007; 120: 1360-7.
2. Lessard A, Turcotte H, Cormier Y, Boulet LP. Obesity and asthma: a specific phenotype? Chest 2008; 134: 317-23.
3. Boulet LP, Franssen E. Influence of obesity on response to fluticasone with or without salmeterol in moderate asthma. Respir. Med. 2007; 101: 2240-7.
4. Peters-Golden M, Swern A, Bird SS, Hustad CM, Grant E, Edelman JM. Influence of body mass index on the response to asthma controller agents. Eur. Respir. J. 2006; 27: 495-503.
5. Dixon AE, Pratley RE, Forgione PM, Kaminsky DA, Whittaker-Leclair LA, Griffes LA, Garudathri J, Raymond D, Poynter ME, Bunn JY et al. Effects of obesity and bariatric surgery on airway hyperresponsiveness, asthma control, and inflammation. J. Allergy Clin. Immunol. 2011; 128: 508-15.e1-2.
6. Holguin F, Bleecker ER, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN et al. Obesity and asthma: an association modified by age of asthma onset. J. Allergy Clin. Immunol. 2011; 127: 1486-93.e2.
7. Skloot G, Schechter C, Desai A, Togias A. Impaired response to deep inspiration in obesity. J. Appl. Physiol. 2011; 111: 726-34.
8. Salome CM, Munoz PA, Berend N, Thorpe CW, Schachter LM, King GG. Effect of obesity on breathlessness and airway responsiveness to methacholine in non-asthmatic subjects. Int. J. Obes. (Lond) 2008; 32: 502-9.
9. Chapman DG, Berend N, King GG, Salome CM. Increased airway closure is a determinant of airway hyperresponsiveness. Eur. Respir. J. 2008; 32: 1563-9.
10. Mahadev S, Farah CS, King GG, Salome CM. Obesity, expiratory flow limitation and asthma symptoms. Pulm. Pharmacol. Ther. 2012; 26: 438-43.
11. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P et al. Standardisation of spirometry. Eur. Respir. J. 2005; 26: 319-38.
12. Crapo RO, Casaburi R, Coates AL, Enright PL, Hankinson JL, Irvin CG, MacIntyre NR, McKay RT, Wanger JS, Anderson SD et al. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. Am. J. Respir. Crit. Care Med. 2000; 161: 309-29.
13. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am. J. Respir. Crit. Care Med. 1999; 159: 179-87.
14. Mead J. Problems in interpreting common tests of pulmonary mechanical function. In: Macklem P, Permutt S (eds) The Lung in Transition between Death and Disease. Marcel Dekker Inc., New York, 1979; 43-51.
15. Gibbons WJ, Sharma A, Lougheed D, Macklem PT. Detection of excessive bronchoconstriction in asthma. Am. J. Respir. Crit. Care Med. 1996; 153: 582-9.
16. O'Connor G, Sparrow D, Taylor D, Segal M, Weiss S. Analysis of dose-response curves to methacholine. An approach suitable for population studies. Am. Rev. Respir. Dis. 1987; 136: 1412-17.
17. Peat JK, Salome CM, Berry G, Woolcock AJ. Relation of dose-response slope to respiratory symptoms and lung function in a population study of adults living in Busselton, Western Australia. Am. Rev. Respir. Dis. 1992; 146: 860-5.
18. Marsh DG, Bias WB, Ishizaka K. Genetic control of basal serum immunoglobulin E level and its effect on specific reaginic sensitivity. Proc. Natl Acad. Sci. U.S.A. 1974; 71: 3588-92.
19. Chapman DG, Berend N, Horlyck KR, King GG, Salome CM. Does increased baseline ventilation heterogeneity following chest wall strapping predispose to airway hyperresponsiveness? J. Appl. Physiol. 2012; 113: 25-30.
20. Ding DJ, Martin JG, Macklem PT. Effects of lung volume on maximal methacholine-induced bronchoconstriction in normal humans. J. Appl. Physiol. 1987; 62: 1324-30.
21. Torchio R, Gobbi A, Gulotta C, Dellaca R, Tinivella M, Hyatt RE, Brusasco V, Pellegrino R. Mechanical effects of obesity on airway responsiveness in otherwise healthy humans. J. Appl. Physiol. (1985) 2009; 107: 408-16.
22. Rajala MW, Scherer PE. Minireview: the adipocyte-at the crossroads of energy homeostasis, inflammation, and atherosclerosis. Endocrinology 2003; 144: 3765-73.
23. Torday JS, Rehan VK. Stretch-stimulated surfactant synthesis is coordinated by the paracrine actions of PTHrP and leptin. Am. J. Physiol. Lung Cell. Mol. Physiol. 2002; 283: L130-5.
24. Sideleva O, Suratt BT, Black KE, Tharp WG, Pratley RE, Forgione P, Dienz O, Irvin CG, Dixon AE. Obesity and asthma: an inflammatory disease of adipose tissue not the airway. Am. J. Respir. Crit. Care Med. 2012; 186: 598-605.
25. Lugogo NL, Hollingsworth JW, Howell DL, Que LG, Francisco D, Church TD, Potts-Kant EN, Ingram JL, Wang Y, Jung SH et al. Alveolar macrophages from overweight/obese subjects with asthma demonstrate a proinflammatory phenotype. Am. J. Respir. Crit. Care Med. 2012; 186: 404-11.
26. Hohlfeld JM, Schmiedl A, Erpenbeck VJ, Venge P, Krug N. Eosinophil cationic protein alters pulmonary surfactant structure and function in asthma. J. Allergy Clin. Immunol. 2004; 113: 496-502.
27. Nicolacakis K, Skowronski ME, Coreno AJ, West E, Nader NZ, Smith RL, McFadden ER Jr. Observations on the physiological interactions between obesity and asthma. J. Appl. Physiol. 2008; 105: 1533-41.
28. Berg CM, Thelle DS, Rosengren A, Lissner L, Toren K, Olin AC. Decreased fraction of exhaled nitric oxide in obese subjects with asthma symptoms: data from the population study INTERGENE/ADONIX. Chest 2011; 139: 1109-16.
29. D'Angelo E, Pecchiari M, Baraggia P, Saetta M, Balestro E, Milic-Emili J. Low-volume ventilation causes peripheral airway injury and increased airway resistance in normal rabbits. J. Appl. Physiol. 2002; 92: 949-56.
30. Yalcin HC, Perry SF, Ghadiali SN. Influence of airway diameter and cell confluence on epithelial cell injury in an in vitro model of airway reopening. J. Appl. Physiol. 2007; 103: 1796-807.
31. Saraiva SA, Silva AL, Xisto DG, Abreu SC, Silva JD, Silva PL, Teixeira TP, Parra ER, Carvalho AL, Annoni R et al. Impact of obesity on airway and lung parenchyma remodeling in experimental chronic allergic asthma. Respir. Physiol. Neurobiol. 2011;177: 141-8.
32. Oppenheimer BW, Berger KI, Segal LN, Stabile A, Coles KD, Parikh M, Goldring RM. Airway dysfunction in obesity: response to voluntary restoration of end expiratory lung volume. PLoS ONE 2014; 9: e88015.
33. Kim KM, Kim SS, Kwon JW, Jung JW, Kim TW, Lee SH, Min KU, Kim YY, Cho SH. Association between subcutaneous abdominal fat and airway hyperresponsiveness. Allergy Asthma Proc. 2011; 32: 68-73.