메뉴 건너뛰기




Volumn 16, Issue 1, 2015, Pages

A pilot randomized controlled trial of pioglitazone for the treatment of poorly controlled asthma in obesity

Author keywords

Asthma; Asthma control; Obesity; Thiazolidinedione

Indexed keywords

CORTICOSTEROID; METHACHOLINE; NITRIC OXIDE; PIOGLITAZONE; PLACEBO; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIASTHMATIC AGENT; BRONCHOCONSTRICTING AGENT; METHACHOLINE CHLORIDE;

EID: 84960340702     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-015-0303-6     Document Type: Article
Times cited : (36)

References (41)
  • 2
    • 84863894291 scopus 로고    scopus 로고
    • The treatment of asthma in obesity
    • Dixon A. The treatment of asthma in obesity. Expert Rev Respir Med. 2012;6:331-40.
    • (2012) Expert Rev Respir Med , vol.6 , pp. 331-340
    • Dixon, A.1
  • 3
    • 39449101231 scopus 로고    scopus 로고
    • BMI and health status among adults with asthma
    • Vortmann M, Eisner MD. BMI and health status among adults with asthma. Obesity (Silver Spring). 2008;16:146-52.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 146-152
    • Vortmann, M.1    Eisner, M.D.2
  • 4
    • 34748878277 scopus 로고    scopus 로고
    • Influence of obesity on response to fluticasone with or without salmeterol in moderate asthma
    • Boulet LP, Franssen E. Influence of obesity on response to fluticasone with or without salmeterol in moderate asthma. Respir Med. 2007;101:2240-7.
    • (2007) Respir Med , vol.101 , pp. 2240-2247
    • Boulet, L.P.1    Franssen, E.2
  • 7
    • 84872551287 scopus 로고    scopus 로고
    • An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype
    • Holguin F, Comhair SA, Hazen SL, Powers RW, Khatri SS, Bleecker ER, et al. An association between L-arginine/asymmetric dimethyl arginine balance, obesity, and the age of asthma onset phenotype. Am J Respir Crit Care Med. 2013;187:153-9.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 153-159
    • Holguin, F.1    Comhair, S.A.2    Hazen, S.L.3    Powers, R.W.4    Khatri, S.S.5    Bleecker, E.R.6
  • 10
    • 84905712219 scopus 로고    scopus 로고
    • Adiponectin, leptin, and resistin in asthma: basic mechanisms through population studies
    • Sood A, Shore SA. Adiponectin, leptin, and resistin in asthma: basic mechanisms through population studies. J Allergy (Cairo). 2013;2013:785835.
    • (2013) J Allergy (Cairo) , vol.2013 , pp. 785835
    • Sood, A.1    Shore, S.A.2
  • 12
    • 33751545838 scopus 로고    scopus 로고
    • A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis
    • Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, et al. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med. 2006;355:2297-307.
    • (2006) N Engl J Med , vol.355 , pp. 2297-2307
    • Belfort, R.1    Harrison, S.A.2    Brown, K.3    Darland, C.4    Finch, J.5    Hardies, J.6
  • 13
    • 0035888675 scopus 로고    scopus 로고
    • Regulation of peroxisome proliferator-activated receptor gamma expression in human asthmatic airways: relationship with proliferation, apoptosis, and airway remodeling
    • Benayoun L, Letuve S, Druilhe A, Boczkowski J, Dombret MC, Mechighel P, et al. Regulation of peroxisome proliferator-activated receptor gamma expression in human asthmatic airways: relationship with proliferation, apoptosis, and airway remodeling. Am J Respir Crit Care Med. 2001;164:1487-94.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1487-1494
    • Benayoun, L.1    Letuve, S.2    Druilhe, A.3    Boczkowski, J.4    Dombret, M.C.5    Mechighel, P.6
  • 14
    • 1542574200 scopus 로고    scopus 로고
    • Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma
    • Hammad H, de Heer HJ, Soullie T, Angeli V, Trottein F, Hoogsteden HC, et al. Activation of peroxisome proliferator-activated receptor-gamma in dendritic cells inhibits the development of eosinophilic airway inflammation in a mouse model of asthma. Am J Pathol. 2004;164:263-71.
    • (2004) Am J Pathol , vol.164 , pp. 263-271
    • Hammad, H.1    Heer, H.J.2    Soullie, T.3    Angeli, V.4    Trottein, F.5    Hoogsteden, H.C.6
  • 15
    • 33745451812 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice
    • Lee KS, Kim SR, Park SJ, Park HS, Min KH, Jin SM, et al. Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice. J Allergy Clin Immunol. 2006;118:120-7.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 120-127
    • Lee, K.S.1    Kim, S.R.2    Park, S.J.3    Park, H.S.4    Min, K.H.5    Jin, S.M.6
  • 16
    • 2342455049 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model
    • Honda K, Marquillies P, Capron M, Dombrowicz D. Peroxisome proliferator-activated receptor gamma is expressed in airways and inhibits features of airway remodeling in a mouse asthma model. J Allergy Clin Immunol. 2004;113:882-8.
    • (2004) J Allergy Clin Immunol , vol.113 , pp. 882-888
    • Honda, K.1    Marquillies, P.2    Capron, M.3    Dombrowicz, D.4
  • 17
    • 0042624848 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation
    • Woerly G, Honda K, Loyens M, Papin JP, Auwerx J, Staels B, et al. Peroxisome proliferator-activated receptors alpha and gamma down-regulate allergic inflammation and eosinophil activation. J Exp Med. 2003;198:411-21.
    • (2003) J Exp Med , vol.198 , pp. 411-421
    • Woerly, G.1    Honda, K.2    Loyens, M.3    Papin, J.P.4    Auwerx, J.5    Staels, B.6
  • 19
    • 41649116684 scopus 로고    scopus 로고
    • Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma
    • Narala VR, Ranga R, Smith MR, Berlin AA, Standiford TJ, Lukacs NW, et al. Pioglitazone is as effective as dexamethasone in a cockroach allergen-induced murine model of asthma. Respir Res. 2007;8:90.
    • (2007) Respir Res , vol.8 , pp. 90
    • Narala, V.R.1    Ranga, R.2    Smith, M.R.3    Berlin, A.A.4    Standiford, T.J.5    Lukacs, N.W.6
  • 20
    • 70350133800 scopus 로고    scopus 로고
    • Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease
    • Belvisi MG, Mitchell JA. Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br J Pharmacol. 2009;158:994-1003.
    • (2009) Br J Pharmacol , vol.158 , pp. 994-1003
    • Belvisi, M.G.1    Mitchell, J.A.2
  • 21
    • 77951621270 scopus 로고    scopus 로고
    • Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial
    • Richards DB, Bareille P, Lindo EL, Quinn D, Farrow SN. Treatment with a peroxisomal proliferator activated receptor gamma agonist has a modest effect in the allergen challenge model in asthma: a randomised controlled trial. Respir Med. 2010;104:668-74.
    • (2010) Respir Med , vol.104 , pp. 668-674
    • Richards, D.B.1    Bareille, P.2    Lindo, E.L.3    Quinn, D.4    Farrow, S.N.5
  • 23
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356:2457-71.
    • (2007) N Engl J Med , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 24
    • 70449467324 scopus 로고    scopus 로고
    • CHICAGO, PERISCOPE and PROactive: CV risk modification in diabetes with pioglitazone
    • Betteridge DJ. CHICAGO, PERISCOPE and PROactive: CV risk modification in diabetes with pioglitazone. Fundam Clin Pharmacol. 2009;23:675-9.
    • (2009) Fundam Clin Pharmacol , vol.23 , pp. 675-679
    • Betteridge, D.J.1
  • 25
    • 84875166950 scopus 로고    scopus 로고
    • Pioglitazone and risk of bladder cancer: a meta-analysis of controlled studies
    • Ferwana M, Firwana B, Hasan R, Al-Mallah MH, Kim S, Montori VM, et al. Pioglitazone and risk of bladder cancer: a meta-analysis of controlled studies. Diabet Med. 2013;30:1026-32.
    • (2013) Diabet Med , vol.30 , pp. 1026-1032
    • Ferwana, M.1    Firwana, B.2    Hasan, R.3    Al-Mallah, M.H.4    Kim, S.5    Montori, V.M.6
  • 27
    • 33746516349 scopus 로고    scopus 로고
    • Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice
    • Shore SA, Terry RD, Flynt L, Xu A, Hug C. Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice. J Allergy Clin Immunol. 2006;118:389-95.
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 389-395
    • Shore, S.A.1    Terry, R.D.2    Flynt, L.3    Xu, A.4    Hug, C.5
  • 28
    • 84864002783 scopus 로고    scopus 로고
    • Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice
    • Williams AS, Kasahara DI, Verbout NG, Fedulov AV, Zhu M, Si H, et al. Role of the adiponectin binding protein, T-cadherin (Cdh13), in allergic airways responses in mice. PLoS One. 2012;7, e41088.
    • (2012) PLoS One , vol.7
    • Williams, A.S.1    Kasahara, D.I.2    Verbout, N.G.3    Fedulov, A.V.4    Zhu, M.5    Si, H.6
  • 30
    • 84868219117 scopus 로고    scopus 로고
    • Adiponectin induces pro-inflammatory programs in human macrophages and CD4+ T cells
    • Cheng X, Folco EJ, Shimizu K, Libby P. Adiponectin induces pro-inflammatory programs in human macrophages and CD4+ T cells. J Biol Chem. 2012;287:36896-904.
    • (2012) J Biol Chem , vol.287 , pp. 36896-36904
    • Cheng, X.1    Folco, E.J.2    Shimizu, K.3    Libby, P.4
  • 31
    • 58149462249 scopus 로고    scopus 로고
    • The expression of adiponectin receptors and the effects of adiponectin and leptin on airway smooth muscle cells
    • Shin JH, Kim JH, Lee WY, Shim JY. The expression of adiponectin receptors and the effects of adiponectin and leptin on airway smooth muscle cells. Yonsei Med J. 2008;49:804-10.
    • (2008) Yonsei Med J , vol.49 , pp. 804-810
    • Shin, J.H.1    Kim, J.H.2    Lee, W.Y.3    Shim, J.Y.4
  • 32
    • 84862922916 scopus 로고    scopus 로고
    • Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation
    • Konter JM, Parker JL, Baez E, Li SZ, Ranscht B, Denzel M, et al. Adiponectin attenuates lipopolysaccharide-induced acute lung injury through suppression of endothelial cell activation. J Immunol. 2012;188:854-63.
    • (2012) J Immunol , vol.188 , pp. 854-863
    • Konter, J.M.1    Parker, J.L.2    Baez, E.3    Li, S.Z.4    Ranscht, B.5    Denzel, M.6
  • 35
    • 84872124577 scopus 로고    scopus 로고
    • Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma
    • Arteaga-Solis E, Zee T, Emala CW, Vinson C, Wess J, Karsenty G. Inhibition of leptin regulation of parasympathetic signaling as a cause of extreme body weight-associated asthma. Cell Metab. 2013;17:35-48.
    • (2013) Cell Metab , vol.17 , pp. 35-48
    • Arteaga-Solis, E.1    Zee, T.2    Emala, C.W.3    Vinson, C.4    Wess, J.5    Karsenty, G.6
  • 37
    • 84873957568 scopus 로고    scopus 로고
    • Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial
    • Esteghamati A, Noshad S, Rabizadeh S, Ghavami M, Zandieh A, Nakhjavani M. Comparative effects of metformin and pioglitazone on omentin and leptin concentrations in patients with newly diagnosed diabetes: a randomized clinical trial. Regul Pept. 2013;182:1-6.
    • (2013) Regul Pept , vol.182 , pp. 1-6
    • Esteghamati, A.1    Noshad, S.2    Rabizadeh, S.3    Ghavami, M.4    Zandieh, A.5    Nakhjavani, M.6
  • 38
    • 84906308272 scopus 로고    scopus 로고
    • Obesity and symptoms of depression contribute independently to the poor asthma control of obesity
    • Kapadia SG, Wei C, Bartlett SJ, Lang J, Wise RA, Dixon AE, et al. Obesity and symptoms of depression contribute independently to the poor asthma control of obesity. Respir Med. 2014;108:1100-7.
    • (2014) Respir Med , vol.108 , pp. 1100-1107
    • Kapadia, S.G.1    Wei, C.2    Bartlett, S.J.3    Lang, J.4    Wise, R.A.5    Dixon, A.E.6
  • 39
    • 80051964077 scopus 로고    scopus 로고
    • Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity
    • Dixon AE, Clerisme-Beaty EM, Sugar EA, Cohen RI, Lang JE, Brown ED, et al. Effects of obstructive sleep apnea and gastroesophageal reflux disease on asthma control in obesity. J Asthma. 2011;48:707-13.
    • (2011) J Asthma , vol.48 , pp. 707-713
    • Dixon, A.E.1    Clerisme-Beaty, E.M.2    Sugar, E.A.3    Cohen, R.I.4    Lang, J.E.5    Brown, E.D.6
  • 40
    • 55449096455 scopus 로고    scopus 로고
    • No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice
    • Shore SA, Williams ES, Zhu M. No effect of metformin on the innate airway hyperresponsiveness and increased responses to ozone observed in obese mice. J Appl Physiol (1985). 2008;105:1127-33.
    • (2008) J Appl Physiol (1985) , vol.105 , pp. 1127-1133
    • Shore, S.A.1    Williams, E.S.2    Zhu, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.