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Volumn 5, Issue 10, 2016, Pages

Natural killer cell recognition of in vivo drug-induced senescent multiple myeloma cells

Author keywords

DNAM 1; immunomodulation; melphalan; multiple myeloma; natural killer cell; NKG2D; senescence

Indexed keywords

BETA GALACTOSIDASE; CD69 ANTIGEN; LIGAND; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MELPHALAN;

EID: 84988726239     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1218105     Document Type: Article
Times cited : (47)

References (69)
  • 1
    • 0038277105 scopus 로고    scopus 로고
    • Tumor cell senescence in cancer treatment
    • 12782571
    • I.B.Roninson. Tumor cell senescence in cancer treatment. Cancer Res 2003; 63:2705-15; PMID:12782571
    • (2003) Cancer Res , vol.63 , pp. 2705-2715
    • Roninson, I.B.1
  • 2
    • 0035736138 scopus 로고    scopus 로고
    • If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells
    • 11991684
    • I.B.Roninson, E.V.Broude, B.D.Chang. If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells. Drug Resist Updat 2001; 4:303-13; PMID:11991684; http://dx.doi.org/10.1054/drup.2001.0213
    • (2001) Drug Resist Updat , vol.4 , pp. 303-313
    • Roninson, I.B.1    Broude, E.V.2    Chang, B.D.3
  • 3
    • 0037086268 scopus 로고    scopus 로고
    • DNA damage is able to induce senescence in tumor cells in vitro and in vivo
    • 11912168
    • R.H.te Poele, A.L.Okorokov, L.Jardine, J.Cummings, S.P.Joel. DNA damage is able to induce senescence in tumor cells in vitro and in vivo. Cancer Res 2002; 62:1876-83; PMID:11912168
    • (2002) Cancer Res , vol.62 , pp. 1876-1883
    • te Poele, R.H.1    Okorokov, A.L.2    Jardine, L.3    Cummings, J.4    Joel, S.P.5
  • 4
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: when bad things happen to good cells
    • 17667954
    • J.Campisi, F.d'Adda di Fagagna. Cellular senescence:when bad things happen to good cells. Nat Rev Mol Cell Biol 2007; 8:729-40; PMID:17667954; http://dx.doi.org/10.1038/nrm2233
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 729-740
    • Campisi, J.1    d'Adda di Fagagna, F.2
  • 5
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • 13905658
    • L.Hayflick, P.S.Moorhead. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25:585-621; PMID:13905658; http://dx.doi.org/10.1016/0014-4827(61)90192-6
    • (1961) Exp Cell Res , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 6
    • 78349257844 scopus 로고    scopus 로고
    • The essence of senescence
    • 21078816
    • T.Kuilman, C.Michaloglou, W.J.Mooi, D.S.Peeper. The essence of senescence. Genes Dev 2010; 24:2463-79; PMID:21078816; http://dx.doi.org/10.1101/gad.1971610
    • (2010) Genes Dev , vol.24 , pp. 2463-2479
    • Kuilman, T.1    Michaloglou, C.2    Mooi, W.J.3    Peeper, D.S.4
  • 7
    • 84904702784 scopus 로고    scopus 로고
    • Cellular senescence: from physiology to pathology
    • 24954210
    • D.Munoz-Espin, M.Serrano. Cellular senescence:from physiology to pathology. Nat Rev Mol Cell Biol 2014; 15:482-96; PMID:24954210; http://dx.doi.org/10.1038/nrm3823
    • (2014) Nat Rev Mol Cell Biol , vol.15 , pp. 482-496
    • Munoz-Espin, D.1    Serrano, M.2
  • 11
    • 84919487020 scopus 로고    scopus 로고
    • Senescence helps regeneration
    • 25535913
    • M.Serrano. Senescence helps regeneration. Dev Cell 2014; 31:671-2; PMID:25535913; http://dx.doi.org/10.1016/j.devcel.2014.12.007
    • (2014) Dev Cell , vol.31 , pp. 671-672
    • Serrano, M.1
  • 12
    • 84864306922 scopus 로고    scopus 로고
    • Immune surveillance of senescent cells–biological significance in cancer- and non-cancer pathologies
    • 22470164
    • L.Hoenicke, L.Zender. Immune surveillance of senescent cells–biological significance in cancer- and non-cancer pathologies. Carcinogenesis 2012; 33:1123-6; PMID:22470164; http://dx.doi.org/10.1093/carcin/bgs124
    • (2012) Carcinogenesis , vol.33 , pp. 1123-1126
    • Hoenicke, L.1    Zender, L.2
  • 13
    • 72949096792 scopus 로고    scopus 로고
    • Senescence in tumours: evidence from mice and humans
    • 20029423
    • M.Collado, M.Serrano. Senescence in tumours:evidence from mice and humans. Nat Rev Cancer 2010; 10:51-7; PMID:20029423; http://dx.doi.org/10.1038/nrc2772
    • (2010) Nat Rev Cancer , vol.10 , pp. 51-57
    • Collado, M.1    Serrano, M.2
  • 14
    • 85047694328 scopus 로고    scopus 로고
    • Cellular senescence in cancer treatment: friend or foe?
    • 14722606
    • P.Kahlem, B.Dorken, C.A.Schmitt. Cellular senescence in cancer treatment:friend or foe? J Clin Invest 2004; 113:169-74; PMID:14722606; http://dx.doi.org/10.1172/JCI20784
    • (2004) J Clin Invest , vol.113 , pp. 169-174
    • Kahlem, P.1    Dorken, B.2    Schmitt, C.A.3
  • 15
    • 45749134564 scopus 로고    scopus 로고
    • The anticancer immune response: indispensable for therapeutic success?
    • 18523649
    • L.Zitvogel, L.Apetoh, F.Ghiringhelli, F.Andre, A.Tesniere, G.Kroemer. The anticancer immune response:indispensable for therapeutic success? J Clin Invest 2008; 118:1991-2001; PMID:18523649; http://dx.doi.org/10.1172/JCI35180
    • (2008) J Clin Invest , vol.118 , pp. 1991-2001
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3    Andre, F.4    Tesniere, A.5    Kroemer, G.6
  • 16
    • 37549032137 scopus 로고    scopus 로고
    • Immunological aspects of cancer chemotherapy
    • 18097448
    • L.Zitvogel, L.Apetoh, F.Ghiringhelli, G.Kroemer. Immunological aspects of cancer chemotherapy. Nat Rev Immunol 2008; 8:59-73; PMID:18097448; http://dx.doi.org/10.1038/nri2216
    • (2008) Nat Rev Immunol , vol.8 , pp. 59-73
    • Zitvogel, L.1    Apetoh, L.2    Ghiringhelli, F.3    Kroemer, G.4
  • 18
    • 33748145109 scopus 로고    scopus 로고
    • The role of the NKG2D receptor for tumor immunity
    • 16914326
    • J.D.Coudert, W.Held. The role of the NKG2D receptor for tumor immunity. Semin Cancer Biol 2006; 16:333-43; PMID:16914326; http://dx.doi.org/10.1016/j.semcancer.2006.07.008
    • (2006) Semin Cancer Biol , vol.16 , pp. 333-343
    • Coudert, J.D.1    Held, W.2
  • 19
    • 59649095271 scopus 로고    scopus 로고
    • DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors
    • 19029380
    • S.Gilfillan, C.J.Chan, M.Cella, N.M.Haynes, A.S.Rapaport, K.S.Boles, D.M.Andrews, M.J.Smyth, M.Colonna. DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors. J Exp Med 2008; 205:2965-73; PMID:19029380; http://dx.doi.org/10.1084/jem.20081752
    • (2008) J Exp Med , vol.205 , pp. 2965-2973
    • Gilfillan, S.1    Chan, C.J.2    Cella, M.3    Haynes, N.M.4    Rapaport, A.S.5    Boles, K.S.6    Andrews, D.M.7    Smyth, M.J.8    Colonna, M.9
  • 20
    • 11144299492 scopus 로고    scopus 로고
    • NK cell recognition
    • 15771571
    • L.L.Lanier. NK cell recognition. Annu Rev Immunol 2005; 23:225-74; PMID:15771571; http://dx.doi.org/10.1146/annurev.immunol.23.021704.115526
    • (2005) Annu Rev Immunol , vol.23 , pp. 225-274
    • Lanier, L.L.1
  • 22
    • 0142197631 scopus 로고    scopus 로고
    • Roles of the NKG2D immunoreceptor and its ligands
    • 14523385
    • D.H.Raulet. Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 2003; 3:781-90; PMID:14523385; http://dx.doi.org/10.1038/nri1199
    • (2003) Nat Rev Immunol , vol.3 , pp. 781-790
    • Raulet, D.H.1
  • 23
    • 84904861169 scopus 로고    scopus 로고
    • Immune surveillance of unhealthy cells by natural killer cells
    • 24135717
    • A.Iannello, D.H.Raulet. Immune surveillance of unhealthy cells by natural killer cells. Cold Spring Harb Symp Quant Biol 2013; 78:249-57; PMID:24135717; http://dx.doi.org/10.1101/sqb.2013.78.020255
    • (2013) Cold Spring Harb Symp Quant Biol , vol.78 , pp. 249-257
    • Iannello, A.1    Raulet, D.H.2
  • 24
    • 68849105814 scopus 로고    scopus 로고
    • Oncogenic stress sensed by the immune system: role of natural killer cell receptors
    • 19629084
    • D.H.Raulet, N.Guerra. Oncogenic stress sensed by the immune system:role of natural killer cell receptors. Nat Rev Immunol 2009; 9:568-80; PMID:19629084; http://dx.doi.org/10.1038/nri2604
    • (2009) Nat Rev Immunol , vol.9 , pp. 568-580
    • Raulet, D.H.1    Guerra, N.2
  • 25
    • 84896692416 scopus 로고    scopus 로고
    • Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma
    • 24498552
    • A.Soriani, C.Fionda, B.Ricci, M.L.Iannitto, M.Cippitelli, A.Santoni. Chemotherapy-elicited upregulation of NKG2D and DNAM-1 ligands as a therapeutic target in multiple myeloma. Oncoimmunology 2013; 2:e26663; PMID:24498552; http://dx.doi.org/10.4161/onci.26663
    • (2013) Oncoimmunology , vol.2
    • Soriani, A.1    Fionda, C.2    Ricci, B.3    Iannitto, M.L.4    Cippitelli, M.5    Santoni, A.6
  • 27
    • 84876134219 scopus 로고    scopus 로고
    • Granule exocytosis mediates immune surveillance of senescent cells
    • 22751116
    • A.Sagiv, A.Biran, M.Yon, J.Simon, S.W.Lowe, V.Krizhanovsky. Granule exocytosis mediates immune surveillance of senescent cells. Oncogene 2013; 32:1971-7; PMID:22751116; http://dx.doi.org/10.1038/onc.2012.206
    • (2013) Oncogene , vol.32 , pp. 1971-1977
    • Sagiv, A.1    Biran, A.2    Yon, M.3    Simon, J.4    Lowe, S.W.5    Krizhanovsky, V.6
  • 28
    • 65349131915 scopus 로고    scopus 로고
    • ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
    • 19098271
    • A.Soriani, A.Zingoni, C.Cerboni, M.L.Iannitto, M.R.Ricciardi, V.Di Gialleonardo, M.Cippitelli, C.Fionda, M.T.Petrucci, A.Guarini et al. ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype. Blood 2009; 113:3503-11; PMID:19098271; http://dx.doi.org/10.1182/blood-2008-08-173914
    • (2009) Blood , vol.113 , pp. 3503-3511
    • Soriani, A.1    Zingoni, A.2    Cerboni, C.3    Iannitto, M.L.4    Ricciardi, M.R.5    Di Gialleonardo, V.6    Cippitelli, M.7    Fionda, C.8    Petrucci, M.T.9    Guarini, A.10
  • 29
    • 84899097177 scopus 로고    scopus 로고
    • Immunosurveillance of senescent cancer cells by natural killer cells
    • 24800169
    • A.Iannello, D.H.Raulet. Immunosurveillance of senescent cancer cells by natural killer cells. Oncoimmunology 2014; 3:e27616; PMID:24800169; http://dx.doi.org/10.4161/onci.27616
    • (2014) Oncoimmunology , vol.3
    • Iannello, A.1    Raulet, D.H.2
  • 30
    • 84885458655 scopus 로고    scopus 로고
    • p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells
    • 24043758
    • A.Iannello, T.W.Thompson, M.Ardolino, S.W.Lowe, D.H.Raulet. p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells. J Exp Med 2013; 210:2057-69; PMID:24043758; http://dx.doi.org/10.1084/jem.20130783
    • (2013) J Exp Med , vol.210 , pp. 2057-2069
    • Iannello, A.1    Thompson, T.W.2    Ardolino, M.3    Lowe, S.W.4    Raulet, D.H.5
  • 31
    • 79952781038 scopus 로고    scopus 로고
    • Multiple myeloma
    • 21410373
    • A.Palumbo, K.Anderson. Multiple myeloma. N Engl J Med 2011; 364:1046-60; PMID:21410373; http://dx.doi.org/10.1056/NEJMra1011442
    • (2011) N Engl J Med , vol.364 , pp. 1046-1060
    • Palumbo, A.1    Anderson, K.2
  • 32
    • 19944428928 scopus 로고    scopus 로고
    • HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells
    • 15328155
    • E.Carbone, P.Neri, M.Mesuraca, M.T.Fulciniti, T.Otsuki, D.Pende, V.Groh, T.Spies, G.Pollio, D.Cosman et al. HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood 2005; 105:251-8; PMID:15328155; http://dx.doi.org/10.1182/blood-2004-04-1422
    • (2005) Blood , vol.105 , pp. 251-258
    • Carbone, E.1    Neri, P.2    Mesuraca, M.3    Fulciniti, M.T.4    Otsuki, T.5    Pende, D.6    Groh, V.7    Spies, T.8    Pollio, G.9    Cosman, D.10
  • 34
    • 9244243598 scopus 로고    scopus 로고
    • Analysis of natural killer-associated antigens in peripheral blood and bone marrow of multiple myeloma patients and prognostic implications
    • 8611480
    • R.Garcia-Sanz, M.Gonzalez, A.Orfao, M.J.Moro, J.M.Hernandez, D.Borrego, M.Carnero, F.Casanova, A.Barez, R.Jimenez et al. Analysis of natural killer-associated antigens in peripheral blood and bone marrow of multiple myeloma patients and prognostic implications. Br J Haematol 1996; 93:81-8; PMID:8611480; http://dx.doi.org/10.1046/j.1365-2141.1996.4651006.x
    • (1996) Br J Haematol , vol.93 , pp. 81-88
    • Garcia-Sanz, R.1    Gonzalez, M.2    Orfao, A.3    Moro, M.J.4    Hernandez, J.M.5    Borrego, D.6    Carnero, M.7    Casanova, F.8    Barez, A.9    Jimenez, R.10
  • 36
    • 36249011958 scopus 로고    scopus 로고
    • Clinical stage-depending decrease of NK cell activity in multiple myeloma patients
    • 17873307
    • V.Jurisic, T.Srdic, G.Konjevic, O.Markovic, M.Colovic. Clinical stage-depending decrease of NK cell activity in multiple myeloma patients. Med Oncol 2007; 24:312-7; PMID:17873307; http://dx.doi.org/10.1007/s12032-007-0007-y
    • (2007) Med Oncol , vol.24 , pp. 312-317
    • Jurisic, V.1    Srdic, T.2    Konjevic, G.3    Markovic, O.4    Colovic, M.5
  • 37
    • 0025086435 scopus 로고
    • Natural killer cell activity in monoclonal gammopathies: relation to disease activity
    • 1699786
    • A.Osterborg, B.Nilsson, M.Bjorkholm, G.Holm, H.Mellstedt. Natural killer cell activity in monoclonal gammopathies:relation to disease activity. Eur J Haematol 1990; 45:153-7; PMID:1699786; http://dx.doi.org/10.1111/j.1600-0609.1990.tb00443.x
    • (1990) Eur J Haematol , vol.45 , pp. 153-157
    • Osterborg, A.1    Nilsson, B.2    Bjorkholm, M.3    Holm, G.4    Mellstedt, H.5
  • 38
    • 84931262988 scopus 로고    scopus 로고
    • Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells: role of DNA damage response activation
    • 25609078
    • C.Fionda, M.P.Abruzzese, A.Zingoni, A.Soriani, B.Ricci, R.Molfetta, R.Paolini, A.Santoni, M.Cippitelli. Nitric oxide donors increase PVR/CD155 DNAM-1 ligand expression in multiple myeloma cells:role of DNA damage response activation. BMC Cancer 2015; 15:17; PMID:25609078; http://dx.doi.org/10.1186/s12885-015-1023-5
    • (2015) BMC Cancer , vol.15 , pp. 17
    • Fionda, C.1    Abruzzese, M.P.2    Zingoni, A.3    Soriani, A.4    Ricci, B.5    Molfetta, R.6    Paolini, R.7    Santoni, A.8    Cippitelli, M.9
  • 39
    • 84879115465 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role of STAT3
    • 23686482
    • C.Fionda, G.Malgarini, A.Soriani, A.Zingoni, F.Cecere, M.L.Iannitto, M.R.Ricciardi, V.Federico, M.T.Petrucci, A.Santoni et al. Inhibition of glycogen synthase kinase-3 increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells:role of STAT3. J Immunol 2013; 190:6662-72; PMID:23686482; http://dx.doi.org/10.4049/jimmunol.1201426
    • (2013) J Immunol , vol.190 , pp. 6662-6672
    • Fionda, C.1    Malgarini, G.2    Soriani, A.3    Zingoni, A.4    Cecere, F.5    Iannitto, M.L.6    Ricciardi, M.R.7    Federico, V.8    Petrucci, M.T.9    Santoni, A.10
  • 40
    • 84934300385 scopus 로고    scopus 로고
    • NKG2D and DNAM-1 Ligands: Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma
    • 26161387
    • C.Fionda, A.Soriani, A.Zingoni, A.Santoni, M.Cippitelli. NKG2D and DNAM-1 Ligands:Molecular Targets for NK Cell-Mediated Immunotherapeutic Intervention in Multiple Myeloma. Biomed Res Int 2015; 2015:178698; PMID:26161387; http://dx.doi.org/10.1155/2015/178698
    • (2015) Biomed Res Int , vol.2015 , pp. 178698
    • Fionda, C.1    Soriani, A.2    Zingoni, A.3    Santoni, A.4    Cippitelli, M.5
  • 41
    • 84904265813 scopus 로고    scopus 로고
    • Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1
    • 24913980
    • A.Soriani, M.L.Iannitto, B.Ricci, C.Fionda, G.Malgarini, S.Morrone, G.Peruzzi, M.R.Ricciardi, M.T.Petrucci, M.Cippitelli et al. Reactive oxygen species- and DNA damage response-dependent NK cell activating ligand upregulation occurs at transcriptional levels and requires the transcriptional factor E2F1. J Immunol 2014; 193:950-60; PMID:24913980; http://dx.doi.org/10.4049/jimmunol.1400271
    • (2014) J Immunol , vol.193 , pp. 950-960
    • Soriani, A.1    Iannitto, M.L.2    Ricci, B.3    Fionda, C.4    Malgarini, G.5    Morrone, S.6    Peruzzi, G.7    Ricciardi, M.R.8    Petrucci, M.T.9    Cippitelli, M.10
  • 43
    • 0030977162 scopus 로고    scopus 로고
    • A murine model of human myeloma bone disease
    • 9177864
    • I.R.Garrett, S.Dallas, J.Radl, G.R.Mundy. A murine model of human myeloma bone disease. Bone 1997; 20:515-20; PMID:9177864; http://dx.doi.org/10.1016/S8756-3282(97)00056-2
    • (1997) Bone , vol.20 , pp. 515-520
    • Garrett, I.R.1    Dallas, S.2    Radl, J.3    Mundy, G.R.4
  • 47
    • 25844464180 scopus 로고    scopus 로고
    • Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells
    • 16203869
    • Y.T.Bryceson, M.E.March, D.F.Barber, H.G.Ljunggren, E.O.Long. Cytolytic granule polarization and degranulation controlled by different receptors in resting NK cells. J Exp Med 2005; 202:1001-12; PMID:16203869; http://dx.doi.org/10.1084/jem.20051143
    • (2005) J Exp Med , vol.202 , pp. 1001-1012
    • Bryceson, Y.T.1    March, M.E.2    Barber, D.F.3    Ljunggren, H.G.4    Long, E.O.5
  • 48
    • 0028080739 scopus 로고
    • The CD69 receptor: a multipurpose cell-surface trigger for hematopoietic cells
    • 7945773
    • R.Testi, D.D'Ambrosio, R.De Maria, A.Santoni. The CD69 receptor:a multipurpose cell-surface trigger for hematopoietic cells. Immunol Today 1994; 15:479-83; PMID:7945773; http://dx.doi.org/10.1016/0167-5699(94)90193-7
    • (1994) Immunol Today , vol.15 , pp. 479-483
    • Testi, R.1    D'Ambrosio, D.2    De Maria, R.3    Santoni, A.4
  • 49
    • 0027966088 scopus 로고
    • The activation antigen CD69
    • 7804122
    • S.F.Ziegler, F.Ramsdell, M.R.Alderson. The activation antigen CD69. Stem Cells 1994; 12:456-65; PMID:7804122; http://dx.doi.org/10.1002/stem.5530120502
    • (1994) Stem Cells , vol.12 , pp. 456-465
    • Ziegler, S.F.1    Ramsdell, F.2    Alderson, M.R.3
  • 50
    • 84255197842 scopus 로고    scopus 로고
    • Cancer immunotherapy comes of age
    • 22193102
    • I.Mellman, G.Coukos, G.Dranoff. Cancer immunotherapy comes of age. Nature 2011; 480:480-9; PMID:22193102; http://dx.doi.org/10.1038/nature10673
    • (2011) Nature , vol.480 , pp. 480-489
    • Mellman, I.1    Coukos, G.2    Dranoff, G.3
  • 52
    • 1542781658 scopus 로고    scopus 로고
    • Do tumor-suppressive mechanisms contribute to organism aging by inducing stem cell senescence?
    • 14702099
    • P.G.Pelicci. Do tumor-suppressive mechanisms contribute to organism aging by inducing stem cell senescence? J Clin Invest 2004; 113:4-7; PMID:14702099; http://dx.doi.org/10.1172/JCI200420750
    • (2004) J Clin Invest , vol.113 , pp. 4-7
    • Pelicci, P.G.1
  • 53
    • 84889592106 scopus 로고    scopus 로고
    • A new development in senescence
    • 24267881
    • A.Banito, S.W.Lowe. A new development in senescence. Cell 2013; 155:977-8; PMID:24267881; http://dx.doi.org/10.1016/j.cell.2013.10.050
    • (2013) Cell , vol.155 , pp. 977-978
    • Banito, A.1    Lowe, S.W.2
  • 54
    • 84873638532 scopus 로고    scopus 로고
    • Aging, cellular senescence, and cancer
    • 23140366
    • J.Campisi. Aging, cellular senescence, and cancer. Annu Rev Physiol 2013; 75:685-705; PMID:23140366; http://dx.doi.org/10.1146/annurev-physiol-030212-183653
    • (2013) Annu Rev Physiol , vol.75 , pp. 685-705
    • Campisi, J.1
  • 56
    • 33846937033 scopus 로고    scopus 로고
    • Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
    • 17251933
    • W.Xue, L.Zender, C.Miething, R.A.Dickins, E.Hernando, V.Krizhanovsky, C.Cordon-Cardo, S.W.Lowe. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007; 445:656-60; PMID:17251933; http://dx.doi.org/10.1038/nature05529
    • (2007) Nature , vol.445 , pp. 656-660
    • Xue, W.1    Zender, L.2    Miething, C.3    Dickins, R.A.4    Hernando, E.5    Krizhanovsky, V.6    Cordon-Cardo, C.7    Lowe, S.W.8
  • 58
    • 24144443517 scopus 로고    scopus 로고
    • The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor
    • 15995699
    • S.Gasser, S.Orsulic, E.J.Brown, D.H.Raulet. The DNA damage pathway regulates innate immune system ligands of the NKG2D receptor. Nature 2005; 436:1186-90; PMID:15995699; http://dx.doi.org/10.1038/nature03884
    • (2005) Nature , vol.436 , pp. 1186-1190
    • Gasser, S.1    Orsulic, S.2    Brown, E.J.3    Raulet, D.H.4
  • 59
    • 84871915611 scopus 로고    scopus 로고
    • RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry
    • 23166357
    • H.Jung, B.Hsiung, K.Pestal, E.Procyk, D.H.Raulet. RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med 2012; 209:2409-22; PMID:23166357; http://dx.doi.org/10.1084/jem.20120565
    • (2012) J Exp Med , vol.209 , pp. 2409-2422
    • Jung, H.1    Hsiung, B.2    Pestal, K.3    Procyk, E.4    Raulet, D.H.5
  • 60
    • 84936791354 scopus 로고    scopus 로고
    • Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells
    • 26071561
    • A.Zingoni, F.Cecere, E.Vulpis, C.Fionda, R.Molfetta, A.Soriani, M.T.Petrucci, M.R.Ricciardi, D.Fuerst, M.G.Amendola et al. Genotoxic Stress Induces Senescence-Associated ADAM10-Dependent Release of NKG2D MIC Ligands in Multiple Myeloma Cells. J Immunol 2015; 195:736-48; PMID:26071561; http://dx.doi.org/10.4049/jimmunol.1402643
    • (2015) J Immunol , vol.195 , pp. 736-748
    • Zingoni, A.1    Cecere, F.2    Vulpis, E.3    Fionda, C.4    Molfetta, R.5    Soriani, A.6    Petrucci, M.T.7    Ricciardi, M.R.8    Fuerst, D.9    Amendola, M.G.10
  • 62
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • 9054499
    • M.Serrano, A.W.Lin, M.E.McCurrach, D.Beach, S.W.Lowe. Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 1997; 88:593-602; PMID:9054499; http://dx.doi.org/10.1016/S0092-8674(00)81902-9
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 63
    • 16844373387 scopus 로고    scopus 로고
    • Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers
    • 15805280
    • R.S.Roberson, S.J.Kussick, E.Vallieres, S.Y.Chen, D.Y.Wu. Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers. Cancer Res 2005; 65:2795-803; PMID:15805280; http://dx.doi.org/10.1158/0008-5472.CAN-04-1270
    • (2005) Cancer Res , vol.65 , pp. 2795-2803
    • Roberson, R.S.1    Kussick, S.J.2    Vallieres, E.3    Chen, S.Y.4    Wu, D.Y.5
  • 64
    • 0037013154 scopus 로고    scopus 로고
    • A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy
    • 12015983
    • C.A.Schmitt, J.S.Fridman, M.Yang, S.Lee, E.Baranov, R.M.Hoffman, S.W.Lowe. A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy. Cell 2002; 109:335-46; PMID:12015983; http://dx.doi.org/10.1016/S0092-8674(02)00734-1
    • (2002) Cell , vol.109 , pp. 335-346
    • Schmitt, C.A.1    Fridman, J.S.2    Yang, M.3    Lee, S.4    Baranov, E.5    Hoffman, R.M.6    Lowe, S.W.7
  • 66
    • 84922552740 scopus 로고    scopus 로고
    • Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells
    • 25560408
    • X.Lu, Z.C.Ding, Y.Cao, C.Liu, T.Habtetsion, M.Yu, H.Lemos, H.Salman, H.Xu, A.L.Mellor et al. Alkylating agent melphalan augments the efficacy of adoptive immunotherapy using tumor-specific CD4+ T cells. J Immunol 2015; 194:2011-21; PMID:25560408; http://dx.doi.org/10.4049/jimmunol.1401894
    • (2015) J Immunol , vol.194 , pp. 2011-2021
    • Lu, X.1    Ding, Z.C.2    Cao, Y.3    Liu, C.4    Habtetsion, T.5    Yu, M.6    Lemos, H.7    Salman, H.8    Xu, H.9    Mellor, A.L.10
  • 67
    • 74949127989 scopus 로고    scopus 로고
    • Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo
    • 20010931
    • F.Debacq-Chainiaux, J.D.Erusalimsky, J.Campisi, O.Toussaint. Protocols to detect senescence-associated beta-galactosidase (SA-betagal) activity, a biomarker of senescent cells in culture and in vivo. Nat Protoc 2009; 4:1798-806; PMID:20010931; http://dx.doi.org/10.1038/nprot.2009.191
    • (2009) Nat Protoc , vol.4 , pp. 1798-1806
    • Debacq-Chainiaux, F.1    Erusalimsky, J.D.2    Campisi, J.3    Toussaint, O.4
  • 68
    • 20444408804 scopus 로고    scopus 로고
    • CD8 cell division maintaining cytotoxic memory occurs predominantly in the bone marrow
    • 15944266
    • E.Parretta, G.Cassese, P.Barba, A.Santoni, J.Guardiola, F.Di Rosa. CD8 cell division maintaining cytotoxic memory occurs predominantly in the bone marrow. J Immunol 2005; 174:7654-64; PMID:15944266; http://dx.doi.org/10.4049/jimmunol.174.12.7654
    • (2005) J Immunol , vol.174 , pp. 7654-7664
    • Parretta, E.1    Cassese, G.2    Barba, P.3    Santoni, A.4    Guardiola, J.5    Di Rosa, F.6
  • 69
    • 84888374956 scopus 로고    scopus 로고
    • CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation
    • 24184559
    • A.Ponzetta, G.Sciume, G.Benigni, F.Antonangeli, S.Morrone, A.Santoni, G.Bernardini. CX3CR1 regulates the maintenance of KLRG1+ NK cells into the bone marrow by promoting their entry into circulation. J Immunol 2013; 191:5684-94; PMID:24184559; http://dx.doi.org/10.4049/jimmunol.1300090
    • (2013) J Immunol , vol.191 , pp. 5684-5694
    • Ponzetta, A.1    Sciume, G.2    Benigni, G.3    Antonangeli, F.4    Morrone, S.5    Santoni, A.6    Bernardini, G.7


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