Fucoidan Induces ROS-Dependent Apoptosis in 5637 Human Bladder Cancer Cells by Downregulating Telomerase Activity via Inactivation of the PI3K/Akt Signaling Pathway

Drug Development Research

Volumn 78, Issue 1, 2017, Pages 37-48

  Han, Min Ho ^a   Lee, Dae Sung ^a   Jeong, Jin Woo ^b   Hong, Su Hyun ^b   Choi, Il Whan ^c   Cha, Hee Jae ^d   Kim, Suhkmann ^e   Kim, Heui Soo ^e   Park, Cheol ^b   Kim, Gi Young ^f   Moon, Sung Kwon ^g   Kim, Wun Jae ^h   Hyun Choi, Yung ^a,b  

^a Marine Biodiversity Institute of Korea   (South Korea)

^b Dong Eui University   (South Korea)

^c Inje University   (South Korea)

^d Kosin University   (South Korea)

^e Pusan National University   (South Korea)

^f Jeju National University   (South Korea)

^g Chung Ang University   (South Korea)

^h Chungbuk National University College of Medicine   (South Korea)

Author keywords

fucoidan; ROS; telomerase

Indexed keywords

CYTOCHROME C; FUCOIDIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TELOMERASE; TRANSCRIPTION FACTOR SP1; POLYSACCHARIDE; TERT PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; BLADDER CANCER; CANCER CELL; CELL CYCLE; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; BLADDER TUMOR; CELL SURVIVAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; METABOLISM; MITOCHONDRION; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; DOWN-REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; PHOSPHATIDYLINOSITOL 3-KINASES; POLYSACCHARIDES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TELOMERASE; URINARY BLADDER NEOPLASMS;

EID: 84988661112     PISSN: 02724391     EISSN: 10982299     Source Type: Journal    
DOI: 10.1002/ddr.21367     Document Type: Article

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