Fucoidan inhibits proliferation of the SKM-1 acute myeloid leukaemia cell line via the activation of apoptotic pathways and production of reactive oxygen species

Molecular Medicine Reports

Volumn 12, Issue 5, 2015, Pages 6649-6655

  Wei, Chunmei ^a   Xiao, Qing ^a   Kuang, Xingyi ^a   Zhang, Tao ^a   Yang, Zesong ^a   Wang, Li ^a  

^a THE FIRST AFFILIATED HOSPITAL OF CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

Cell apoptosis; Cell proliferation; Fucoidan; Phosphoinositide 3 kinase AKT; Reactive oxygen species; SKM 1 cells

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 8; CASPASE 9; FAS ANTIGEN; FUCOIDIN; PHOSPHATIDYLINOSITOL 3 KINASE; REACTIVE OXYGEN METABOLITE; POLYSACCHARIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL ACTIVATION; CELL COUNTING; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; G1 PHASE CELL CYCLE CHECKPOINT; G2 PHASE CELL CYCLE CHECKPOINT; HUMAN; HUMAN CELL; MYELODYSPLASTIC SYNDROME; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING; CELL CYCLE CHECKPOINT; DRUG EFFECTS; LEUKEMIA, MYELOID, ACUTE; METABOLISM; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; LEUKEMIA, MYELOID, ACUTE; POLYSACCHARIDES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84943628255     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4252     Document Type: Article

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