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Volumn 72, Issue , 2014, Pages 195-213

Anticancer effects of fucoidan

Author keywords

Akt; Apoptosis; Cancer; Fucoidan; LMWF; PI3K

Indexed keywords

ANTINEOPLASTIC AGENT; FUCOIDIN; POLYSACCHARIDE;

EID: 84904889161     PISSN: 10434526     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-800269-8.00011-7     Document Type: Chapter
Times cited : (29)

References (94)
  • 1
    • 11144297712 scopus 로고    scopus 로고
    • Fucoidan induces apoptosis of human HS Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways
    • Aisa Y., Miyakawa Y., Nakazato T., Shibata H., Saito K., Ikeda Y., et al. Fucoidan induces apoptosis of human HS Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways. American Journal of Hematology 2005, 78(1):7-14.
    • (2005) American Journal of Hematology , vol.78 , Issue.1 , pp. 7-14
    • Aisa, Y.1    Miyakawa, Y.2    Nakazato, T.3    Shibata, H.4    Saito, K.5    Ikeda, Y.6
  • 2
    • 79959618692 scopus 로고    scopus 로고
    • Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo
    • Ale M.T., Maruyama H., Tamauchi H., Mikkelsen J.D., Meyer A.S. Fucoidan from Sargassum sp. and Fucus vesiculosus reduces cell viability of lung carcinoma and melanoma cells in vitro and activates natural killer cells in mice in vivo. International Journal of Biological Macromolecules 2011, 49(3):331-336.
    • (2011) International Journal of Biological Macromolecules , vol.49 , Issue.3 , pp. 331-336
    • Ale, M.T.1    Maruyama, H.2    Tamauchi, H.3    Mikkelsen, J.D.4    Meyer, A.S.5
  • 4
    • 84864466952 scopus 로고    scopus 로고
    • Compositional and structural mass spectrometric analysis of fucoidan preparations from Costaria costata, extracted from alga at different life-stages
    • Anastyuk S.D., Imbs T.I., Shevchenko N.M., Dmitrenok P.S., Zvyagintseva T.N. Compositional and structural mass spectrometric analysis of fucoidan preparations from Costaria costata, extracted from alga at different life-stages. Carbohydrate Polymers 2012, 90:993-1002.
    • (2012) Carbohydrate Polymers , vol.90 , pp. 993-1002
    • Anastyuk, S.D.1    Imbs, T.I.2    Shevchenko, N.M.3    Dmitrenok, P.S.4    Zvyagintseva, T.N.5
  • 5
    • 34250793265 scopus 로고    scopus 로고
    • Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration
    • Arya M., Ahmed H., Silhi N., Williamson M., Patel H.R. Clinical importance and therapeutic implications of the pivotal CXCL12-CXCR4 (chemokine ligand-receptor) interaction in cancer cell migration. Tumor Biology 2007, 28(3):123-131.
    • (2007) Tumor Biology , vol.28 , Issue.3 , pp. 123-131
    • Arya, M.1    Ahmed, H.2    Silhi, N.3    Williamson, M.4    Patel, H.R.5
  • 6
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Ashkenazi A., Dixit V.M. Death receptors: Signaling and modulation. Science 1998, 281(5381):1305-1308.
    • (1998) Science , vol.281 , Issue.5381 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.M.2
  • 7
    • 33748890740 scopus 로고    scopus 로고
    • An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava
    • Athukorala Y., Jung W.-K., Vasanthan T., Jeon Y.-J. An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava. Carbohydrate Polymers 2006, 66(2):184-191.
    • (2006) Carbohydrate Polymers , vol.66 , Issue.2 , pp. 184-191
    • Athukorala, Y.1    Jung, W.-K.2    Vasanthan, T.3    Jeon, Y.-J.4
  • 8
    • 58149288229 scopus 로고    scopus 로고
    • Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets
    • Bachelet L., Bertholon I., Lavigne D., Vassy R., Jandrot-Perrus M., Chaubet F., et al. Affinity of low molecular weight fucoidan for P-selectin triggers its binding to activated human platelets. Biochimica et Biophysica Acta 2009, 1790(2):141-146.
    • (2009) Biochimica et Biophysica Acta , vol.1790 , Issue.2 , pp. 141-146
    • Bachelet, L.1    Bertholon, I.2    Lavigne, D.3    Vassy, R.4    Jandrot-Perrus, M.5    Chaubet, F.6
  • 9
    • 84886265555 scopus 로고    scopus 로고
    • Fucoidan induces G1 phase arrest and apoptosis through caspases-dependent pathway and ROS induction in human breast cancer MCF-7 cells
    • Banafa A.M., Roshan S. Fucoidan induces G1 phase arrest and apoptosis through caspases-dependent pathway and ROS induction in human breast cancer MCF-7 cells. Journal of Huazhong University of Science and Technology 2013, 33(5):717-724.
    • (2013) Journal of Huazhong University of Science and Technology , vol.33 , Issue.5 , pp. 717-724
    • Banafa, A.M.1    Roshan, S.2
  • 10
    • 0038618955 scopus 로고    scopus 로고
    • Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide
    • Berteau O., Mulloy B. Sulfated fucans, fresh perspectives: Structures, functions, and biological properties of sulfated fucans and an overview of enzymes active toward this class of polysaccharide. Glycobiology 2003, 13(6):29-40.
    • (2003) Glycobiology , vol.13 , Issue.6 , pp. 29-40
    • Berteau, O.1    Mulloy, B.2
  • 11
    • 33645131690 scopus 로고    scopus 로고
    • The current status of natural products from marine fungi and their potential as anti-infective agents
    • Bhadury P., Mohammad B.T., Wright P.C. The current status of natural products from marine fungi and their potential as anti-infective agents. Journal of Industrial Microbiology & Biotechnology 2006, 33(5):325-337.
    • (2006) Journal of Industrial Microbiology & Biotechnology , vol.33 , Issue.5 , pp. 325-337
    • Bhadury, P.1    Mohammad, B.T.2    Wright, P.C.3
  • 12
    • 84899667857 scopus 로고    scopus 로고
    • Structural analysis of fucoidans
    • Bilan M.I., Usov A.I. Structural analysis of fucoidans. ChemInform 2009, 40:34.
    • (2009) ChemInform , vol.40 , pp. 34
    • Bilan, M.I.1    Usov, A.I.2
  • 14
    • 67349214601 scopus 로고    scopus 로고
    • MTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3
    • Busch S., Renaud S.J., Schleussner E., Graham C.H., Markert U.R. mTOR mediates human trophoblast invasion through regulation of matrix-remodeling enzymes and is associated with serine phosphorylation of STAT3. Experimental Cell Research 2009, 315(10):1724-1733.
    • (2009) Experimental Cell Research , vol.315 , Issue.10 , pp. 1724-1733
    • Busch, S.1    Renaud, S.J.2    Schleussner, E.3    Graham, C.H.4    Markert, U.R.5
  • 16
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L., Karin M. Mammalian MAP kinase signalling cascades. Nature 2001, 410(6824):37-40.
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 18
    • 0035961371 scopus 로고    scopus 로고
    • A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae
    • Chevolot L., Mulloy B., Ratiskol J., Foucault A., Colliec-Jouault S. A disaccharide repeat unit is the major structure in fucoidans from two species of brown algae. Carbohydrate Research 2001, 330(4):529-535.
    • (2001) Carbohydrate Research , vol.330 , Issue.4 , pp. 529-535
    • Chevolot, L.1    Mulloy, B.2    Ratiskol, J.3    Foucault, A.4    Colliec-Jouault, S.5
  • 21
    • 34447333662 scopus 로고    scopus 로고
    • A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds
    • Cumashi A., Ushakova N.A., Preobrazhenskaya M.E., D'Incecco A., Piccoli A., Totani L., et al. A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology 2007, 17(5):541-552.
    • (2007) Glycobiology , vol.17 , Issue.5 , pp. 541-552
    • Cumashi, A.1    Ushakova, N.A.2    Preobrazhenskaya, M.E.3    D'Incecco, A.4    Piccoli, A.5    Totani, L.6
  • 22
    • 0033535350 scopus 로고    scopus 로고
    • Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis
    • Desagher S., Osen-Sand A., Nichols A., Eskes R., Montessuit S., Lauper S., et al. Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis. The Journal of Cell Biology 1999, 144(5):891-901.
    • (1999) The Journal of Cell Biology , vol.144 , Issue.5 , pp. 891-901
    • Desagher, S.1    Osen-Sand, A.2    Nichols, A.3    Eskes, R.4    Montessuit, S.5    Lauper, S.6
  • 23
    • 0035913184 scopus 로고    scopus 로고
    • Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum
    • Duarte M.E., Cardoso M.A., Noseda M.D., Cerezo A.S. Structural studies on fucoidans from the brown seaweed Sargassum stenophyllum. Carbohydrate Research 2001, 333(4):281-293.
    • (2001) Carbohydrate Research , vol.333 , Issue.4 , pp. 281-293
    • Duarte, M.E.1    Cardoso, M.A.2    Noseda, M.D.3    Cerezo, A.S.4
  • 25
    • 79960107906 scopus 로고    scopus 로고
    • Fucoidans from brown seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural characteristics and anticancer activity
    • Ermakova S., Sokolova R., Kim S.-M., Um B.-H., Isakov V., Zvyagintseva T. Fucoidans from brown seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural characteristics and anticancer activity. Applied Biochemistry and Biotechnology 2011, 164(6):841-850.
    • (2011) Applied Biochemistry and Biotechnology , vol.164 , Issue.6 , pp. 841-850
    • Ermakova, S.1    Sokolova, R.2    Kim, S.-M.3    Um, B.-H.4    Isakov, V.5    Zvyagintseva, T.6
  • 26
    • 0033981577 scopus 로고    scopus 로고
    • Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane
    • Eskes R., Desagher S., Antonsson B., Martinou J.-C. Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane. Molecular and Cellular Biology 2000, 20(3):929-935.
    • (2000) Molecular and Cellular Biology , vol.20 , Issue.3 , pp. 929-935
    • Eskes, R.1    Desagher, S.2    Antonsson, B.3    Martinou, J.-C.4
  • 27
    • 69249159493 scopus 로고    scopus 로고
    • Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro
    • Fukahori S., Yano H., Akiba J., Ogasawara S., Momosaki S., Sanada S., et al. Fucoidan, a major component of brown seaweed, prohibits the growth of human cancer cell lines in vitro. Molecular Medicine Reports 2008, 1:537-542.
    • (2008) Molecular Medicine Reports , vol.1 , pp. 537-542
    • Fukahori, S.1    Yano, H.2    Akiba, J.3    Ogasawara, S.4    Momosaki, S.5    Sanada, S.6
  • 28
    • 57349089536 scopus 로고    scopus 로고
    • Toxicological evaluation of fucoidan from Cladosiphon okamuranus
    • Gideon T.P., Rengasamy R. Toxicological evaluation of fucoidan from Cladosiphon okamuranus. Journal of Medicinal Food 2008, 11(4):638-642.
    • (2008) Journal of Medicinal Food , vol.11 , Issue.4 , pp. 638-642
    • Gideon, T.P.1    Rengasamy, R.2
  • 29
    • 77958566257 scopus 로고    scopus 로고
    • Future scenarios for the treatment of advanced non-small cell lung cancer: Focus on taxane-containing regimens
    • Grossi F., Kubota K., Cappuzzo F., de Marinis F., Gridelli C., Aita M., et al. Future scenarios for the treatment of advanced non-small cell lung cancer: Focus on taxane-containing regimens. The Oncologist 2010, 15(10):1102-1112.
    • (2010) The Oncologist , vol.15 , Issue.10 , pp. 1102-1112
    • Grossi, F.1    Kubota, K.2    Cappuzzo, F.3    de Marinis, F.4    Gridelli, C.5    Aita, M.6
  • 30
    • 27644507488 scopus 로고    scopus 로고
    • Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells
    • Haneji K., Matsuda T., Tomita M., Kawakami H., Ohshiro K., Uchihara J.-N., et al. Fucoidan extracted from Cladosiphon okamuranus Tokida induces apoptosis of human T-cell leukemia virus type 1-infected T-cell lines and primary adult T-cell leukemia cells. Nutrition and Cancer 2005, 52(2):189-201.
    • (2005) Nutrition and Cancer , vol.52 , Issue.2 , pp. 189-201
    • Haneji, K.1    Matsuda, T.2    Tomita, M.3    Kawakami, H.4    Ohshiro, K.5    Uchihara, J.-N.6
  • 32
    • 64949154349 scopus 로고    scopus 로고
    • Effect of fucoidan on the biotinidase kinetics in human hepatocellular carcinoma
    • Hayakawa K., Nagamine T. Effect of fucoidan on the biotinidase kinetics in human hepatocellular carcinoma. Anticancer Research 2009, 29(4):1211-1217.
    • (2009) Anticancer Research , vol.29 , Issue.4 , pp. 1211-1217
    • Hayakawa, K.1    Nagamine, T.2
  • 33
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner M.O. The biochemistry of apoptosis. Nature 2000, 407(6805):770-776.
    • (2000) Nature , vol.407 , Issue.6805 , pp. 770-776
    • Hengartner, M.O.1
  • 34
    • 79958758613 scopus 로고    scopus 로고
    • Bioactive compounds in seaweed: Functional food applications and legislation
    • Holdt S.L., Kraan S. Bioactive compounds in seaweed: Functional food applications and legislation. Journal of Applied Phycology 2011, 23(3):543-597.
    • (2011) Journal of Applied Phycology , vol.23 , Issue.3 , pp. 543-597
    • Holdt, S.L.1    Kraan, S.2
  • 35
    • 84875935094 scopus 로고    scopus 로고
    • Fucoidan induces changes in the epithelial-mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer
    • Hsu H.-Y., Lin T.-Y., Hwang P.-A., Chen R.-H., Tsao S.-M., Hsu J. Fucoidan induces changes in the epithelial-mesenchymal transition and decreases metastasis by enhancing ubiquitin-dependent TGFβ receptor degradation in breast cancer. Carcinogenesis 2013, 34:874-884.
    • (2013) Carcinogenesis , vol.34 , pp. 874-884
    • Hsu, H.-Y.1    Lin, T.-Y.2    Hwang, P.-A.3    Chen, R.-H.4    Tsao, S.-M.5    Hsu, J.6
  • 36
    • 0034190272 scopus 로고    scopus 로고
    • Activator protein 1 (AP-1)- and nuclear factor κB (NF-κB)-dependent transcriptional events in carcinogenesis
    • Hsu T.-C., Young M.R., Cmarik J., Colburn N.H. Activator protein 1 (AP-1)- and nuclear factor κB (NF-κB)-dependent transcriptional events in carcinogenesis. Free Radical Biology and Medicine 2000, 28(9):1338-1348.
    • (2000) Free Radical Biology and Medicine , vol.28 , Issue.9 , pp. 1338-1348
    • Hsu, T.-C.1    Young, M.R.2    Cmarik, J.3    Colburn, N.H.4
  • 38
    • 79958746720 scopus 로고
    • Norwegian Institute of Seaweed Research, Akademisk Trykningssentral, Blindern, Oslo, Report 9
    • Jensen A. Component sugars of some common brown algae 1956, Norwegian Institute of Seaweed Research, Akademisk Trykningssentral, Blindern, Oslo, Report 9.
    • (1956) Component sugars of some common brown algae
    • Jensen, A.1
  • 39
    • 79851484446 scopus 로고    scopus 로고
    • Chemical structures and bioactivities of sulfated polysaccharides from marine algae
    • Jiao G., Yu G., Zhang J., Ewart H.S. Chemical structures and bioactivities of sulfated polysaccharides from marine algae. Marine Drugs 2011, 9(2):196-223.
    • (2011) Marine Drugs , vol.9 , Issue.2 , pp. 196-223
    • Jiao, G.1    Yu, G.2    Zhang, J.3    Ewart, H.S.4
  • 40
    • 77956153829 scopus 로고    scopus 로고
    • The mechanism of fucoidan induced apoptosis in leukemic cells: Involvement of ERK1/2, JNK, glutathione, and nitric oxide
    • Jin J.O., Song M.G., Kim Y.N., Park J.I., Kwak J.Y. The mechanism of fucoidan induced apoptosis in leukemic cells: Involvement of ERK1/2, JNK, glutathione, and nitric oxide. Molecular Carcinogenesis 2010, 49(8):771-782.
    • (2010) Molecular Carcinogenesis , vol.49 , Issue.8 , pp. 771-782
    • Jin, J.O.1    Song, M.G.2    Kim, Y.N.3    Park, J.I.4    Kwak, J.Y.5
  • 41
    • 0037169358 scopus 로고    scopus 로고
    • Apoptosis-A link between cancer genetics and chemotherapy
    • Johnstone R.W., Ruefli A.A., Lowe S.W. Apoptosis-A link between cancer genetics and chemotherapy. Cell 2002, 108(2):153-164.
    • (2002) Cell , vol.108 , Issue.2 , pp. 153-164
    • Johnstone, R.W.1    Ruefli, A.A.2    Lowe, S.W.3
  • 42
    • 0027255417 scopus 로고
    • Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis
    • Kaufmann S.H., Desnoyers S., Ottaviano Y., Davidson N.E., Poirier G.G. Specific proteolytic cleavage of poly(ADP-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Research 1993, 53(17):3976-3985.
    • (1993) Cancer Research , vol.53 , Issue.17 , pp. 3976-3985
    • Kaufmann, S.H.1    Desnoyers, S.2    Ottaviano, Y.3    Davidson, N.E.4    Poirier, G.G.5
  • 43
    • 77955766528 scopus 로고    scopus 로고
    • Fucoidan present in brown algae induces apoptosis of human colon cancer cells
    • Kim E., Park S., Lee J.-Y., Park J. Fucoidan present in brown algae induces apoptosis of human colon cancer cells. BMC Gastroenterology 2010, 10(1):96.
    • (2010) BMC Gastroenterology , vol.10 , Issue.1 , pp. 96
    • Kim, E.1    Park, S.2    Lee, J.-Y.3    Park, J.4
  • 44
    • 0037437728 scopus 로고    scopus 로고
    • Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities
    • Koyanagi S., Tanigawa N., Nakagawa H., Soeda S., Shimeno H. Oversulfation of fucoidan enhances its anti-angiogenic and antitumor activities. Biochemical Pharmacology 2003, 65(2):173-179.
    • (2003) Biochemical Pharmacology , vol.65 , Issue.2 , pp. 173-179
    • Koyanagi, S.1    Tanigawa, N.2    Nakagawa, H.3    Soeda, S.4    Shimeno, H.5
  • 47
    • 33845995846 scopus 로고    scopus 로고
    • Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1
    • Lake A.C., Vassy R., Di Benedetto M., Lavigne D., Le Visage C., Perret G.Y., et al. Low molecular weight fucoidan increases VEGF165-induced endothelial cell migration by enhancing VEGF165 binding to VEGFR-2 and NRP1. Journal of Biological Chemistry 2006, 281(49):37844-37852.
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.49 , pp. 37844-37852
    • Lake, A.C.1    Vassy, R.2    Di Benedetto, M.3    Lavigne, D.4    Le Visage, C.5    Perret, G.Y.6
  • 48
    • 56349106887 scopus 로고    scopus 로고
    • Simple separation of anticoagulant sulfated galactan from marine red algae
    • Lee S.-H., Athukorala Y., Lee J.-S., Jeon Y.-J. Simple separation of anticoagulant sulfated galactan from marine red algae. Journal of Applied Phycology 2008, 20(6):1053-1059.
    • (2008) Journal of Applied Phycology , vol.20 , Issue.6 , pp. 1053-1059
    • Lee, S.-H.1    Athukorala, Y.2    Lee, J.-S.3    Jeon, Y.-J.4
  • 49
    • 40849083373 scopus 로고    scopus 로고
    • Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells
    • Lee N.Y., Ermakova S.P., Zvyagintseva T.N., Kang K.W., Dong Z., Choi H.S. Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 Cl41 cells. Food and Chemical Toxicology 2008, 46(5):1793-1800.
    • (2008) Food and Chemical Toxicology , vol.46 , Issue.5 , pp. 1793-1800
    • Lee, N.Y.1    Ermakova, S.P.2    Zvyagintseva, T.N.3    Kang, K.W.4    Dong, Z.5    Choi, H.S.6
  • 50
    • 84870615277 scopus 로고    scopus 로고
    • Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways
    • Lee H., Kim J.-S., Kim E. Fucoidan from seaweed Fucus vesiculosus inhibits migration and invasion of human lung cancer cell via PI3K-Akt-mTOR pathways. PLoS One 2012, 7(11):e50624.
    • (2012) PLoS One , vol.7 , Issue.11
    • Lee, H.1    Kim, J.-S.2    Kim, E.3
  • 51
    • 54249096028 scopus 로고    scopus 로고
    • Caspases in apoptosis and beyond
    • Li J., Yuan J. Caspases in apoptosis and beyond. Oncogene 2008, 27(48):6194-6206.
    • (2008) Oncogene , vol.27 , Issue.48 , pp. 6194-6206
    • Li, J.1    Yuan, J.2
  • 52
    • 38049019482 scopus 로고    scopus 로고
    • Expression and significance of PTEN/PI3K signal transduction-related proteins in non-small cell lung cancer
    • Liao D., Wang L., Zhang X., Liu M. Expression and significance of PTEN/PI3K signal transduction-related proteins in non-small cell lung cancer. Ai Zheng Aizheng Chinese Journal of Cancer 2006, 25(10):1238.
    • (2006) Ai Zheng Aizheng Chinese Journal of Cancer , vol.25 , Issue.10 , pp. 1238
    • Liao, D.1    Wang, L.2    Zhang, X.3    Liu, M.4
  • 53
    • 84861818270 scopus 로고    scopus 로고
    • Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells
    • Liu F., Wang J., Chang A.K., Liu B., Yang L., Li Q., et al. Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells. Phytomedicine 2012, 19:797-803.
    • (2012) Phytomedicine , vol.19 , pp. 797-803
    • Liu, F.1    Wang, J.2    Chang, A.K.3    Liu, B.4    Yang, L.5    Li, Q.6
  • 55
    • 84862815238 scopus 로고    scopus 로고
    • Comparison of the effects of marchantin C and fucoidan on sFlt-1 and angiogenesis in glioma microenvironment
    • Lv Y., Song Q., Shao Q., Gao W., Mao H., Lou H., et al. Comparison of the effects of marchantin C and fucoidan on sFlt-1 and angiogenesis in glioma microenvironment. Journal of Pharmacy and Pharmacology 2012, 64(4):604-609.
    • (2012) Journal of Pharmacy and Pharmacology , vol.64 , Issue.4 , pp. 604-609
    • Lv, Y.1    Song, Q.2    Shao, Q.3    Gao, W.4    Mao, H.5    Lou, H.6
  • 56
    • 77950276043 scopus 로고    scopus 로고
    • Antiviral activity of sulfated polysaccharide from the brown algae Laminaria japonica against avian influenza A (H5N1) virus infection in the cultured cells
    • Makarenkova I., Deriabin P., L'vov D., Zviagintseva T., Besednova N. Antiviral activity of sulfated polysaccharide from the brown algae Laminaria japonica against avian influenza A (H5N1) virus infection in the cultured cells. Voprosy Virusologii 2010, 55(1):41.
    • (2010) Voprosy Virusologii , vol.55 , Issue.1 , pp. 41
    • Makarenkova, I.1    Deriabin, P.2    L'vov, D.3    Zviagintseva, T.4    Besednova, N.5
  • 57
    • 0028800947 scopus 로고
    • Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl
    • Martin S., Reutelingsperger C., McGahon A.J., Rader J.A., Van Schie R., LaFace D.M., et al. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: Inhibition by overexpression of Bcl-2 and Abl. The Journal of Experimental Medicine 1995, 182(5):1545-1556.
    • (1995) The Journal of Experimental Medicine , vol.182 , Issue.5 , pp. 1545-1556
    • Martin, S.1    Reutelingsperger, C.2    McGahon, A.J.3    Rader, J.A.4    Van Schie, R.5    LaFace, D.M.6
  • 58
    • 33846256216 scopus 로고    scopus 로고
    • The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu)
    • Maruyama H., Tamauchi H., Iizuka M., Nakano T. The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Medica 2006, 72(15):1415.
    • (2006) Planta Medica , vol.72 , Issue.15 , pp. 1415
    • Maruyama, H.1    Tamauchi, H.2    Iizuka, M.3    Nakano, T.4
  • 59
    • 0037092631 scopus 로고    scopus 로고
    • Effect of fucoidan on fibroblast growth factor-2 induced angiogenesis in vitro
    • Matou S., Helley D., Chabut D., Bros A., Fischer A.-M. Effect of fucoidan on fibroblast growth factor-2 induced angiogenesis in vitro. Thrombosis Research 2002, 106(4):213-221.
    • (2002) Thrombosis Research , vol.106 , Issue.4 , pp. 213-221
    • Matou, S.1    Helley, D.2    Chabut, D.3    Bros, A.4    Fischer, A.-M.5
  • 61
    • 77952296059 scopus 로고    scopus 로고
    • Sulfated polysaccharides and their anticoagulant activity: A review
    • Mestechkina N., Shcherbukhin V. Sulfated polysaccharides and their anticoagulant activity: A review. Applied Biochemistry and Microbiology 2010, 46(3):267-273.
    • (2010) Applied Biochemistry and Microbiology , vol.46 , Issue.3 , pp. 267-273
    • Mestechkina, N.1    Shcherbukhin, V.2
  • 64
    • 0032127699 scopus 로고    scopus 로고
    • Inhibitors of angiogenesis enter phase III testing
    • Nelson N.J. Inhibitors of angiogenesis enter phase III testing. Journal of the National Cancer Institute 1998, 90(13):960-963.
    • (1998) Journal of the National Cancer Institute , vol.90 , Issue.13 , pp. 960-963
    • Nelson, N.J.1
  • 66
  • 68
    • 84871769191 scopus 로고    scopus 로고
    • Therapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings
    • Patel S. Therapeutic importance of sulfated polysaccharides from seaweeds: updating the recent findings. Biotech 2012, 3(2):1-15.
    • (2012) Biotech , vol.3 , Issue.2 , pp. 1-15
    • Patel, S.1
  • 70
    • 0031021970 scopus 로고    scopus 로고
    • Biotechnology and the red seaweed polysaccharide industry: Status, needs and prospects
    • Renn D. Biotechnology and the red seaweed polysaccharide industry: Status, needs and prospects. Trends in Biotechnology 1997, 15(1):9-14.
    • (1997) Trends in Biotechnology , vol.15 , Issue.1 , pp. 9-14
    • Renn, D.1
  • 71
    • 8944256874 scopus 로고    scopus 로고
    • Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line
    • Riou D., Colliec-Jouault S., Pinczon du Sel D., Bosch S., Siavoshian S., Le Bert V., et al. Antitumor and antiproliferative effects of a fucan extracted from ascophyllum nodosum against a non-small-cell bronchopulmonary carcinoma line. Anticancer Research 1996, 16(3A):1213.
    • (1996) Anticancer Research , vol.16 , Issue.3 A , pp. 1213
    • Riou, D.1    Colliec-Jouault, S.2    Pinczon du Sel, D.3    Bosch, S.4    Siavoshian, S.5    Le Bert, V.6
  • 72
    • 80052628027 scopus 로고    scopus 로고
    • Radiolabeled fucoidan as a p-selectin targeting agent for in vivo imaging of platelet-rich thrombus and endothelial activation
    • Rouzet F., Bachelet-Violette L., Alsac J.-M., Suzuki M., Meulemans A., Louedec L., et al. Radiolabeled fucoidan as a p-selectin targeting agent for in vivo imaging of platelet-rich thrombus and endothelial activation. Journal of Nuclear Medicine 2011, 52(9):1433-1440.
    • (2011) Journal of Nuclear Medicine , vol.52 , Issue.9 , pp. 1433-1440
    • Rouzet, F.1    Bachelet-Violette, L.2    Alsac, J.-M.3    Suzuki, M.4    Meulemans, A.5    Louedec, L.6
  • 73
    • 77956619235 scopus 로고    scopus 로고
    • Dose-response relationship for lung cancer induction at radiotherapy dose
    • Schneider U., Stipper A., Besserer J. Dose-response relationship for lung cancer induction at radiotherapy dose. Zeitschrift für Medizinische Physik 2010, 20(3):206-214.
    • (2010) Zeitschrift für Medizinische Physik , vol.20 , Issue.3 , pp. 206-214
    • Schneider, U.1    Stipper, A.2    Besserer, J.3
  • 77
    • 0037400975 scopus 로고    scopus 로고
    • A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?
    • Smalley K.S. A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?. International Journal of Cancer 2003, 104(5):527-532.
    • (2003) International Journal of Cancer , vol.104 , Issue.5 , pp. 527-532
    • Smalley, K.S.1
  • 78
    • 1442359848 scopus 로고    scopus 로고
    • The interplay between the Bcl-2 family and death receptor-mediated apoptosis
    • Sprick M.R., Walczak H. The interplay between the Bcl-2 family and death receptor-mediated apoptosis. Biochimica et Biophysica Acta 2004, 1644(2):125-132.
    • (2004) Biochimica et Biophysica Acta , vol.1644 , Issue.2 , pp. 125-132
    • Sprick, M.R.1    Walczak, H.2
  • 80
    • 0033858344 scopus 로고    scopus 로고
    • Chemical characterization of acetyl fucoidan and alginate from commercially cultured Cladosiphon okamuranus
    • Tako M., Yoza E., Tohma S. Chemical characterization of acetyl fucoidan and alginate from commercially cultured Cladosiphon okamuranus. Botanica Marina 2000, 43(4):393-398.
    • (2000) Botanica Marina , vol.43 , Issue.4 , pp. 393-398
    • Tako, M.1    Yoza, E.2    Tohma, S.3
  • 81
    • 34250796744 scopus 로고    scopus 로고
    • Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells
    • Teruya T., Konishi T., Uechi S., Tamaki H., Tako M. Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells. International Journal of Biological Macromolecules 2007, 41(3):221-226.
    • (2007) International Journal of Biological Macromolecules , vol.41 , Issue.3 , pp. 221-226
    • Teruya, T.1    Konishi, T.2    Uechi, S.3    Tamaki, H.4    Tako, M.5
  • 83
    • 81455158705 scopus 로고    scopus 로고
    • Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: Isolation, structural characteristics and antitumor activity
    • Vishchuk O.S., Ermakova S.P., Zvyagintseva T.N. Sulfated polysaccharides from brown seaweeds Saccharina japonica and Undaria pinnatifida: Isolation, structural characteristics and antitumor activity. Carbohydrate Research 2011, 346(17):2769-2776.
    • (2011) Carbohydrate Research , vol.346 , Issue.17 , pp. 2769-2776
    • Vishchuk, O.S.1    Ermakova, S.P.2    Zvyagintseva, T.N.3
  • 84
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T., Penninger J.M. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 2004, 23(16):2838-2849.
    • (2004) Oncogene , vol.23 , Issue.16 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 85
    • 71849093174 scopus 로고    scopus 로고
    • Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica
    • Wang J., Zhang Q., Zhang Z., Song H., Li P. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from Laminaria japonica. International Journal of Biological Macromolecules 2010, 46(1):6-12.
    • (2010) International Journal of Biological Macromolecules , vol.46 , Issue.1 , pp. 6-12
    • Wang, J.1    Zhang, Q.2    Zhang, Z.3    Song, H.4    Li, P.5
  • 86
    • 34248597048 scopus 로고    scopus 로고
    • Role of mitogen-activated protein kinase kinase 4 in cancer
    • Whitmarsh A., Davis R. Role of mitogen-activated protein kinase kinase 4 in cancer. Oncogene 2007, 26(22):3172-3184.
    • (2007) Oncogene , vol.26 , Issue.22 , pp. 3172-3184
    • Whitmarsh, A.1    Davis, R.2
  • 87
    • 43049124720 scopus 로고    scopus 로고
    • Signal cross talks for sustained MAPK activation and cell migration: The potential role of reactive oxygen species
    • Wu W.-S., Wu J.-R., Hu C.-T. Signal cross talks for sustained MAPK activation and cell migration: The potential role of reactive oxygen species. Cancer and Metastasis Reviews 2008, 27(2):303-314.
    • (2008) Cancer and Metastasis Reviews , vol.27 , Issue.2 , pp. 303-314
    • Wu, W.-S.1    Wu, J.-R.2    Hu, C.-T.3
  • 89
    • 28944446844 scopus 로고    scopus 로고
    • Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells
    • Ye J., Li Y., Teruya K., Katakura Y., Ichikawa A., Eto H., et al. Enzyme-digested fucoidan extracts derived from seaweed Mozuku of Cladosiphon novae-caledoniae kylin inhibit invasion and angiogenesis of tumor cells. Cytotechnology 2005, 47(1-3):117-126.
    • (2005) Cytotechnology , vol.47 , Issue.1-3 , pp. 117-126
    • Ye, J.1    Li, Y.2    Teruya, K.3    Katakura, Y.4    Ichikawa, A.5    Eto, H.6
  • 90
    • 15944409932 scopus 로고    scopus 로고
    • Fucoidan inhibits the development of proteinuria in active Heymann nephritis
    • Zhang Q., Li N., Zhao T., Qi H., Xu Z., Li Z. Fucoidan inhibits the development of proteinuria in active Heymann nephritis. Phytotherapy Research 2005, 19(1):50-53.
    • (2005) Phytotherapy Research , vol.19 , Issue.1 , pp. 50-53
    • Zhang, Q.1    Li, N.2    Zhao, T.3    Qi, H.4    Xu, Z.5    Li, Z.6
  • 91
    • 80855135589 scopus 로고    scopus 로고
    • Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways
    • Zhang Z., Teruya K., Eto H., Shirahata S. Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways. PLoS One 2011, 6(11):1-14.
    • (2011) PLoS One , vol.6 , Issue.11 , pp. 1-14
    • Zhang, Z.1    Teruya, K.2    Eto, H.3    Shirahata, S.4
  • 92
    • 84875446913 scopus 로고    scopus 로고
    • Induction of apoptosis by low molecular weight fucoidan through calcium and caspase dependent mitochondrial pathways in MDA-MB-231 breast cancer cells
    • Zhang Z., Teruya K., Eto H., Shirahata S. Induction of apoptosis by low molecular weight fucoidan through calcium and caspase dependent mitochondrial pathways in MDA-MB-231 breast cancer cells. Bioscience, Biotechnology, and Biochemistry 2013, 77:235-242.
    • (2013) Bioscience, Biotechnology, and Biochemistry , vol.77 , pp. 235-242
    • Zhang, Z.1    Teruya, K.2    Eto, H.3    Shirahata, S.4
  • 93
    • 77951667889 scopus 로고    scopus 로고
    • Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation
    • Zhu Z., Zhang Q., Chen L., Ren S., Xu P., Tang Y., et al. Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation. Thrombosis Research 2010, 125(5):419-426.
    • (2010) Thrombosis Research , vol.125 , Issue.5 , pp. 419-426
    • Zhu, Z.1    Zhang, Q.2    Chen, L.3    Ren, S.4    Xu, P.5    Tang, Y.6
  • 94
    • 0029278080 scopus 로고
    • Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii)
    • Zhuang C., Itoh H., Mizuno T., Ito H. Antitumor active fucoidan from the brown seaweed, umitoranoo (Sargassum thunbergii). Bioscience, Biotechnology, and Biochemistry 1995, 59(4):563.
    • (1995) Bioscience, Biotechnology, and Biochemistry , vol.59 , Issue.4 , pp. 563
    • Zhuang, C.1    Itoh, H.2    Mizuno, T.3    Ito, H.4


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